JP2009522054A5 - - Google Patents
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- Publication number
- JP2009522054A5 JP2009522054A5 JP2008549520A JP2008549520A JP2009522054A5 JP 2009522054 A5 JP2009522054 A5 JP 2009522054A5 JP 2008549520 A JP2008549520 A JP 2008549520A JP 2008549520 A JP2008549520 A JP 2008549520A JP 2009522054 A5 JP2009522054 A5 JP 2009522054A5
- Authority
- JP
- Japan
- Prior art keywords
- dialysis
- solution
- combinations
- group
- heparin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000000502 dialysis Methods 0.000 claims 29
- 238000000034 method Methods 0.000 claims 28
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims 27
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims 24
- 239000000385 dialysis solution Substances 0.000 claims 19
- 239000000243 solution Substances 0.000 claims 18
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims 17
- 229920000669 heparin Polymers 0.000 claims 17
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 16
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 15
- 229960002897 heparin Drugs 0.000 claims 13
- LCTONWCANYUPML-UHFFFAOYSA-M Pyruvate Chemical compound CC(=O)C([O-])=O LCTONWCANYUPML-UHFFFAOYSA-M 0.000 claims 12
- 230000003204 osmotic effect Effects 0.000 claims 12
- 229940076788 pyruvate Drugs 0.000 claims 12
- 239000000872 buffer Substances 0.000 claims 11
- 230000001954 sterilising effect Effects 0.000 claims 11
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 10
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 10
- 239000008103 glucose Substances 0.000 claims 10
- 229920002683 Glycosaminoglycan Polymers 0.000 claims 9
- 239000000543 intermediate Substances 0.000 claims 9
- 230000004102 tricarboxylic acid cycle Effects 0.000 claims 9
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims 8
- 239000004310 lactic acid Substances 0.000 claims 8
- 235000014655 lactic acid Nutrition 0.000 claims 8
- 239000003055 low molecular weight heparin Substances 0.000 claims 8
- 229940127215 low-molecular weight heparin Drugs 0.000 claims 8
- 238000004659 sterilization and disinfection Methods 0.000 claims 8
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 claims 6
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 claims 6
- 239000002253 acid Substances 0.000 claims 6
- 239000003792 electrolyte Substances 0.000 claims 6
- 239000002357 osmotic agent Substances 0.000 claims 6
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims 5
- 229920001612 Hydroxyethyl starch Polymers 0.000 claims 5
- 229920000881 Modified starch Polymers 0.000 claims 5
- 239000004368 Modified starch Substances 0.000 claims 5
- 229940050526 hydroxyethylstarch Drugs 0.000 claims 5
- 235000019426 modified starch Nutrition 0.000 claims 5
- 229920000642 polymer Polymers 0.000 claims 5
- 229920005862 polyol Polymers 0.000 claims 5
- 150000003077 polyols Chemical class 0.000 claims 5
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical group OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims 4
- LCTONWCANYUPML-UHFFFAOYSA-N Pyruvic acid Chemical compound CC(=O)C(O)=O LCTONWCANYUPML-UHFFFAOYSA-N 0.000 claims 4
- 239000003795 chemical substances by application Substances 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 150000001413 amino acids Chemical class 0.000 claims 3
- 108090000765 processed proteins & peptides Proteins 0.000 claims 3
- 230000000694 effects Effects 0.000 claims 2
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 claims 2
- 238000010438 heat treatment Methods 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 229940107700 pyruvic acid Drugs 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000003607 modifier Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/326,236 US20070155672A1 (en) | 2006-01-05 | 2006-01-05 | Sterilized peritoneal dialysis solutions containing heparin |
| PCT/US2006/062077 WO2007079338A2 (en) | 2006-01-05 | 2006-12-14 | Sterilized peritoneal dialysis solutions containing heparin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009522054A JP2009522054A (ja) | 2009-06-11 |
| JP2009522054A5 true JP2009522054A5 (https=) | 2010-01-28 |
Family
ID=38225289
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008549520A Withdrawn JP2009522054A (ja) | 2006-01-05 | 2006-12-14 | ヘパリンを含む滅菌済腹膜透析溶液 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20070155672A1 (https=) |
| EP (1) | EP1988908A2 (https=) |
| JP (1) | JP2009522054A (https=) |
| CN (1) | CN101394855A (https=) |
| AR (1) | AR058923A1 (https=) |
| MX (1) | MX2008008701A (https=) |
| TW (1) | TW200800237A (https=) |
| WO (1) | WO2007079338A2 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090286740A1 (en) * | 2008-05-15 | 2009-11-19 | Fibrex Medical Research & Development Gmbh | Peptides and derivatives thereof, the manufacturing thereof as well as their use for preparing a therapeutically and/or preventively active pharmaceutical composition |
| BR112017014467A2 (pt) * | 2015-01-30 | 2018-01-16 | Fresenius Kabi Deutschland Gmbh | uso de uma mistura de polímeros modificados de glicose para reduzir a metástase tumoral |
| CN110269867B (zh) * | 2018-03-14 | 2022-06-21 | 必康生技（香港）有限公司 | 用于生物流体净化的组合物 |
| CN114504953B (zh) * | 2022-03-14 | 2023-06-16 | 上海翊科聚合物科技有限公司 | 一种中空纤维血液透析膜的制备方法 |
| CN118436679B (zh) * | 2024-05-07 | 2024-09-17 | 南京汉科明德医疗科技有限公司 | 一种高稳定性的艾考糊精透析液及其制备方法和应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3030272A (en) * | 1960-05-26 | 1962-04-17 | Abbott Lab | Stable heaparin solution |
| DE69320078T2 (de) * | 1992-02-04 | 1999-03-25 | Baxter International Inc., Deerfield, Ill. 60015 | Peritonealdialyselösungen die mindestens ein Dipeptid enthalten |
| SE9900043D0 (sv) * | 1999-01-11 | 1999-01-11 | Astra Ab | New use |
| IT1274351B (it) * | 1994-10-06 | 1997-07-17 | Alfa Wassermann Spa | Uso di alcuni glicosaminoglicani nella dialisi peritoneale. |
| CA2155910C (en) * | 1995-08-11 | 1999-12-14 | George Wu | Biocompatible aqueous solution for use in continuous ambulatory peritoneal dialysis |
| JP4882054B2 (ja) * | 2000-09-13 | 2012-02-22 | 独立行政法人科学技術振興機構 | 腹膜透析液およびその調製法 |
| US20060046975A1 (en) * | 2002-12-10 | 2006-03-02 | Ola Carlsson | Method for preparing a medical solution for the manufacture of a medicament for peritoneal dialysis |
| US7141544B2 (en) * | 2003-10-10 | 2006-11-28 | Baxter International, Inc. | Stabilization of pharmaceutical protein formulations with small peptides |
-
2006
- 2006-01-05 US US11/326,236 patent/US20070155672A1/en not_active Abandoned
- 2006-12-14 EP EP06849137A patent/EP1988908A2/en not_active Withdrawn
- 2006-12-14 WO PCT/US2006/062077 patent/WO2007079338A2/en not_active Ceased
- 2006-12-14 MX MX2008008701A patent/MX2008008701A/es not_active Application Discontinuation
- 2006-12-14 CN CNA200680050532XA patent/CN101394855A/zh active Pending
- 2006-12-14 JP JP2008549520A patent/JP2009522054A/ja not_active Withdrawn
- 2006-12-18 TW TW095147387A patent/TW200800237A/zh unknown
-
2007
- 2007-01-04 AR ARP070100045A patent/AR058923A1/es not_active Application Discontinuation
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