JP2009519903A5 - - Google Patents
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- Publication number
- JP2009519903A5 JP2009519903A5 JP2008542509A JP2008542509A JP2009519903A5 JP 2009519903 A5 JP2009519903 A5 JP 2009519903A5 JP 2008542509 A JP2008542509 A JP 2008542509A JP 2008542509 A JP2008542509 A JP 2008542509A JP 2009519903 A5 JP2009519903 A5 JP 2009519903A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- dimethyl
- ylsulfanyl
- ylmethyl
- thiophene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CC(CC1)C*C1=C Chemical compound CC(CC1)C*C1=C 0.000 description 1
- NMMDOQBBANJZNV-UHFFFAOYSA-N CCC(c1ccc(C(NCC(N=N)=N)=O)[s]1)Sc(cc1C)cc(C)c1-c1ccc(C(C)(C)C)cc1 Chemical compound CCC(c1ccc(C(NCC(N=N)=N)=O)[s]1)Sc(cc1C)cc(C)c1-c1ccc(C(C)(C)C)cc1 NMMDOQBBANJZNV-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73969205P | 2005-11-23 | 2005-11-23 | |
| US60/739,692 | 2005-11-23 | ||
| PCT/US2006/061132 WO2007120284A2 (en) | 2005-11-23 | 2006-11-21 | Glucagon receptor antagonists, preparation and therapeutic uses |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009519903A JP2009519903A (ja) | 2009-05-21 |
| JP2009519903A5 true JP2009519903A5 (https=) | 2009-12-03 |
| JP5140599B2 JP5140599B2 (ja) | 2013-02-06 |
Family
ID=38521482
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008542509A Expired - Fee Related JP5140599B2 (ja) | 2005-11-23 | 2006-11-21 | グルカゴン受容体アンタゴニスト、並びにその調製及び治療への使用 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7807702B2 (https=) |
| EP (1) | EP1957484B1 (https=) |
| JP (1) | JP5140599B2 (https=) |
| CN (1) | CN101312963B (https=) |
| AT (1) | ATE459619T1 (https=) |
| AU (1) | AU2006342059B2 (https=) |
| BR (1) | BRPI0618745A2 (https=) |
| CA (1) | CA2629311C (https=) |
| CY (1) | CY1110922T1 (https=) |
| DE (1) | DE602006012725D1 (https=) |
| DK (1) | DK1957484T3 (https=) |
| ES (1) | ES2339599T3 (https=) |
| PL (1) | PL1957484T3 (https=) |
| PT (1) | PT1957484E (https=) |
| SI (1) | SI1957484T1 (https=) |
| WO (1) | WO2007120284A2 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1968921B (zh) * | 2004-06-14 | 2011-11-23 | 伊莱利利公司 | 胰高血糖素受体拮抗剂、制备和治疗用途 |
| KR20190126460A (ko) | 2007-02-09 | 2019-11-11 | 메타베이시스 테라퓨틱스, 인크. | 글루카곤 수용체의 길항제 |
| EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| CA2770298C (en) | 2008-08-13 | 2017-06-20 | Metabasis Therapeutics, Inc. | Glucagon antagonists |
| WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
| WO2011157827A1 (de) | 2010-06-18 | 2011-12-22 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
| TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
| TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
| MX2013006768A (es) | 2010-12-23 | 2013-07-22 | Pfizer | Moduladores de receptor de glucagon. |
| HRP20161177T1 (hr) | 2011-02-08 | 2016-11-04 | Pfizer Inc. | Modulator glukagonskog receptora |
| US8871758B2 (en) | 2011-03-08 | 2014-10-28 | Sanofi | Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
| WO2012120052A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| EP2683699B1 (de) | 2011-03-08 | 2015-06-24 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| US8828995B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
| EP2683705B1 (de) | 2011-03-08 | 2015-04-22 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| AU2012288493B2 (en) | 2011-07-22 | 2015-08-06 | Pfizer Inc. | Quinolinyl glucagon receptor modulators |
| WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| EP2760862B1 (en) | 2011-09-27 | 2015-10-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| EP3065736B1 (en) | 2013-11-04 | 2018-11-14 | Merck Sharp & Dohme Corp. | Glucagon receptor antagonist compounds, compositions thereof, and methods of use |
| WO2015191900A1 (en) | 2014-06-12 | 2015-12-17 | Ligand Pharmaceuticals, Inc. | Glucagon antagonists |
| WO2019160940A1 (en) | 2018-02-13 | 2019-08-22 | Ligand Pharmaceuticals Incorporated | Glucagon receptor antagonists |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9420557D0 (en) * | 1994-10-12 | 1994-11-30 | Zeneca Ltd | Aromatic compounds |
| PL359619A1 (en) * | 2000-06-23 | 2004-08-23 | Novo Nordisk A/S | Glucagon antagonists/inverse agonists |
| EP1463715A1 (en) * | 2001-12-03 | 2004-10-06 | Novo Nordisk A/S | Novel glucagon antagonists |
| AU2003233780A1 (en) | 2002-06-27 | 2004-01-19 | Novo Nordisk A/S | Novel glucagon antagonists/inverse agonists |
| AU2003291959A1 (en) | 2002-12-20 | 2004-07-14 | Novo Nordisk A/S | Novel glucagon antagonists |
| US8318760B2 (en) | 2005-03-21 | 2012-11-27 | Merck Sharp & Dohme Corp. | Substituted aryl and heteroaryl derivatives, compositions containing such compounds and methods of use |
-
2006
- 2006-11-21 PL PL06850798T patent/PL1957484T3/pl unknown
- 2006-11-21 AT AT06850798T patent/ATE459619T1/de active
- 2006-11-21 US US12/094,406 patent/US7807702B2/en not_active Expired - Fee Related
- 2006-11-21 DE DE602006012725T patent/DE602006012725D1/de active Active
- 2006-11-21 EP EP06850798A patent/EP1957484B1/en not_active Not-in-force
- 2006-11-21 SI SI200630650T patent/SI1957484T1/sl unknown
- 2006-11-21 WO PCT/US2006/061132 patent/WO2007120284A2/en not_active Ceased
- 2006-11-21 CN CN2006800438950A patent/CN101312963B/zh not_active Expired - Fee Related
- 2006-11-21 AU AU2006342059A patent/AU2006342059B2/en not_active Ceased
- 2006-11-21 JP JP2008542509A patent/JP5140599B2/ja not_active Expired - Fee Related
- 2006-11-21 BR BRPI0618745-5A patent/BRPI0618745A2/pt not_active IP Right Cessation
- 2006-11-21 PT PT06850798T patent/PT1957484E/pt unknown
- 2006-11-21 DK DK06850798.7T patent/DK1957484T3/da active
- 2006-11-21 CA CA2629311A patent/CA2629311C/en not_active Expired - Fee Related
- 2006-11-21 ES ES06850798T patent/ES2339599T3/es active Active
-
2010
- 2010-04-23 CY CY20101100366T patent/CY1110922T1/el unknown