JP2009519313A - 医薬組成物 - Google Patents

医薬組成物 Download PDF

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Publication number
JP2009519313A
JP2009519313A JP2008545097A JP2008545097A JP2009519313A JP 2009519313 A JP2009519313 A JP 2009519313A JP 2008545097 A JP2008545097 A JP 2008545097A JP 2008545097 A JP2008545097 A JP 2008545097A JP 2009519313 A JP2009519313 A JP 2009519313A
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JP
Japan
Prior art keywords
composition
composition according
drug
stearic acid
ethylcellulose
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Pending
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JP2008545097A
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English (en)
Japanese (ja)
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JP2009519313A5 (https=
Inventor
スミス アラン
マーガレット ダイアー アン
Original Assignee
アルキメデス ディヴェロプメント リミテッド
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Application filed by アルキメデス ディヴェロプメント リミテッド filed Critical アルキメデス ディヴェロプメント リミテッド
Publication of JP2009519313A publication Critical patent/JP2009519313A/ja
Publication of JP2009519313A5 publication Critical patent/JP2009519313A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2008545097A 2005-12-15 2006-12-15 医薬組成物 Pending JP2009519313A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0525461.0A GB0525461D0 (en) 2005-12-15 2005-12-15 Pharmaceutical compositions
PCT/GB2006/004710 WO2007068948A2 (en) 2005-12-15 2006-12-15 Pharmaceutical sustained release compositions comprising in particular thyroid hormones

Publications (2)

Publication Number Publication Date
JP2009519313A true JP2009519313A (ja) 2009-05-14
JP2009519313A5 JP2009519313A5 (https=) 2009-12-24

Family

ID=35736122

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008545097A Pending JP2009519313A (ja) 2005-12-15 2006-12-15 医薬組成物

Country Status (8)

Country Link
US (1) US8460702B2 (https=)
EP (1) EP1978950A2 (https=)
JP (1) JP2009519313A (https=)
BR (1) BRPI0619934A2 (https=)
CA (1) CA2634006C (https=)
GB (1) GB0525461D0 (https=)
IL (1) IL192091A (https=)
WO (1) WO2007068948A2 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008057464A2 (en) * 2006-11-01 2008-05-15 King Pharmaceuticals Research And Development, Inc. Compositions and methods for improving the bioavailability of liothyronine
WO2013096596A1 (en) * 2011-12-20 2013-06-27 Latham Keith R Sustained drug release and improved product stability using non-covalent particle coating methods
EP3125873B1 (en) * 2014-04-04 2020-06-03 Pharmaquest International Center, LLC Disintegrating monolithic modified release tablets containing quadri-layer extended release granules
DK3006045T3 (en) * 2014-10-07 2017-07-17 Cyprumed Gmbh Pharmaceutical formulations for oral administration of peptide or protein drugs
US10695309B2 (en) 2017-03-31 2020-06-30 Western New England University Sustained-release liothyronine formulations, method of preparation and method of use thereof
WO2020044314A1 (en) 2018-08-31 2020-03-05 Opko Ireland Global Holdings, Ltd. Vitamin d pediatric dosage forms, methods of making and using
US20220409567A1 (en) * 2021-06-23 2022-12-29 Thomas Winston Adjuvant and complementary therapies for the treatment of cancer

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05255081A (ja) * 1991-12-30 1993-10-05 Akzo Nv 持続性放出甲状腺作用性組成物
US6288117B1 (en) * 2000-03-23 2001-09-11 North Shore-Long Island Jewish Research Institute Method for treating congestive heart failure
JP2002526402A (ja) * 1998-10-01 2002-08-20 ノバルティス アクチエンゲゼルシャフト 新規徐放性経口製剤
US6500459B1 (en) * 1999-07-21 2002-12-31 Harinderpal Chhabra Controlled onset and sustained release dosage forms and the preparation thereof
WO2004043452A1 (en) * 2002-11-13 2004-05-27 Bracco S.P.A. 3,5,3’-triiodothyronine sulfate as thyromimetic agent and pharmaceutical formulations thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4806359A (en) 1987-04-22 1989-02-21 Mcneilab, Inc. Iburprofen sustained release matrix and process
US4820522A (en) 1987-07-27 1989-04-11 Mcneilab, Inc. Oral sustained release acetaminophen formulation and process
GB9401892D0 (en) * 1994-02-01 1994-03-30 Boots Co Plc Therapeutic agents
US6469035B1 (en) * 1997-07-31 2002-10-22 Eugenio A. Cefali Methods of pretreating hyperlipidemic individuals with a flush inhibiting agent prior to the start of single daily dose nicotinic acid therapy to reduce flushing provoked by nicotinic acid
US6365180B1 (en) 1998-01-20 2002-04-02 Glenn A. Meyer Oral liquid compositions
EP1049459B1 (en) 1998-01-20 2009-04-22 Applied Analytical Industries, Inc. Oral liquid compositions
DE19821625C1 (de) * 1998-05-15 2000-01-05 Merck Patent Gmbh Pharmazeutische Zubereitung
US6190696B1 (en) * 1998-06-08 2001-02-20 Pieter J. Groenewoud Stabilized thyroxine medications
CN1187052C (zh) 2000-03-30 2005-02-02 布里斯托尔-迈尔斯斯奎布公司 含有司他夫定(stavudine)的持续释放微球
EP1274401B2 (en) * 2000-04-10 2014-08-13 Teva Pharmaceutical Industries Ltd. Stable pharmaceutical compositions containing 7-substituted-3,5-dihydroxyheptanoic acids or 7-substituted-3,5-dihydroxyheptenoic acids
WO2003075830A2 (en) * 2002-03-14 2003-09-18 Sun Pharmaceutical Industries Limited Oral controlled drug delivery system containing carbamazepine
AU2006230557A1 (en) * 2005-03-31 2006-10-05 King Pharmaceuticals Research & Development, Inc. Controlled release pharmaceutical compositions of liothyronine and methods of making and using the same

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05255081A (ja) * 1991-12-30 1993-10-05 Akzo Nv 持続性放出甲状腺作用性組成物
JP2002526402A (ja) * 1998-10-01 2002-08-20 ノバルティス アクチエンゲゼルシャフト 新規徐放性経口製剤
US6500459B1 (en) * 1999-07-21 2002-12-31 Harinderpal Chhabra Controlled onset and sustained release dosage forms and the preparation thereof
US6288117B1 (en) * 2000-03-23 2001-09-11 North Shore-Long Island Jewish Research Institute Method for treating congestive heart failure
WO2004043452A1 (en) * 2002-11-13 2004-05-27 Bracco S.P.A. 3,5,3’-triiodothyronine sulfate as thyromimetic agent and pharmaceutical formulations thereof

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
JPN6012030514; 新・薬剤学総論 改訂第３版, 19870410, ｐｐ．２６２-２６６, 株式会社　南江堂 *
JPN6012030520; Ｚｈａｎｇ　Ｑ　ｅｔ　ａｌ．: 'Ｓｔｕｄｉｅｓ　ｏｎ　ｔｈｅ　ｃｙｃｌｏｓｐｏｒｉｎ　Ａ　ｌｏａｄｅｄ　ｓｔｅａｒｉｃ　ａｃｉｄ　ｎａｎｏｐａｒｔｉｃｌｅｓ．' Ｉｎｔ　Ｊ　Ｐｈａｒｍ． Ｖｏｌ．２００　Ｎｏ．２, 20000510, ｐｐ．１５３-１５９ *
JPN6012030521; Ｙａｎｇ　Ｚ　ｅｔ　ａｌ．: 'Ｐｒｅｐａｒａｔｉｏｎ　ｏｆ　ｃｏｍｐｌｅｘ　ｐｈｅｎｏｂａｒｂｉｔａｌ　ｆｒａｍｅｗｏｒｋ　ｓｕｓｔａｉｎｅｄ-　ｒｅｌｅａｓｅ　ｔａｂｌｅｔｓ' Ｚｈｏｎｇｇｕｏ　Ｙｉｙｕａｎ　Ｙａｏｘｕｅ　Ｚａｚｈｉ Ｖｏｌ．１８　Ｎｏ．７, 1998, ｐｐ．３１３-３１４ *
JPN6012030523; Ｓｔａｒｈａ Ｌ． ａｎｄ Ｃｈａｌａｂａｌａ Ｍ．: 'Ｏｒａｌ ｌｏｎｇ-ａｃｔｉｎｇ ｄｒｕｇｓ． ＶＩ． Ｅｆｆｅｃｔ ｏｆ ｓｔｅａｒｉｃ ａｃｉｄ ａｎｄ ｉｔｓ ｇｌｙｃｅｒｏｌ' Ｃｅｓｋｏ-Ｓｌｏｖｅｎｓｋａ Ｆａｒｍａｃｉｅ Ｖｏｌ．２０ Ｎｏ．２, 1971, ｐｐ．６０-６２ *

Also Published As

Publication number Publication date
CA2634006A1 (en) 2007-06-21
US20090130202A1 (en) 2009-05-21
IL192091A0 (en) 2008-12-29
BRPI0619934A2 (pt) 2011-10-25
GB0525461D0 (en) 2006-01-25
WO2007068948A2 (en) 2007-06-21
EP1978950A2 (en) 2008-10-15
US8460702B2 (en) 2013-06-11
WO2007068948A3 (en) 2007-08-16
CA2634006C (en) 2013-07-30
IL192091A (en) 2012-04-30

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