JP2009518293A5 - - Google Patents

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Publication number
JP2009518293A5
JP2009518293A5 JP2008543435A JP2008543435A JP2009518293A5 JP 2009518293 A5 JP2009518293 A5 JP 2009518293A5 JP 2008543435 A JP2008543435 A JP 2008543435A JP 2008543435 A JP2008543435 A JP 2008543435A JP 2009518293 A5 JP2009518293 A5 JP 2009518293A5
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JP
Japan
Prior art keywords
composition
pirfenidone
administration
medicament
day
Prior art date
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Application number
JP2008543435A
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English (en)
Japanese (ja)
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JP5175740B2 (ja
JP2009518293A (ja
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Publication date
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Priority claimed from PCT/US2006/045750 external-priority patent/WO2007064738A1/en
Publication of JP2009518293A publication Critical patent/JP2009518293A/ja
Publication of JP2009518293A5 publication Critical patent/JP2009518293A5/ja
Application granted granted Critical
Publication of JP5175740B2 publication Critical patent/JP5175740B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2008543435A 2005-12-02 2006-11-29 ピルフェニドン療法に付随する有害事象を低減する方法 Active JP5175740B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74197605P 2005-12-02 2005-12-02
US60/741,976 2005-12-02
PCT/US2006/045750 WO2007064738A1 (en) 2005-12-02 2006-11-29 Methods of reducing adverse events associated with pirfenidone therapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012187515A Division JP2012229275A (ja) 2005-12-02 2012-08-28 ピルフェニドン療法に付随する有害事象を低減する方法

Publications (3)

Publication Number Publication Date
JP2009518293A JP2009518293A (ja) 2009-05-07
JP2009518293A5 true JP2009518293A5 (cg-RX-API-DMAC7.html) 2009-12-17
JP5175740B2 JP5175740B2 (ja) 2013-04-03

Family

ID=37807840

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2008543435A Active JP5175740B2 (ja) 2005-12-02 2006-11-29 ピルフェニドン療法に付随する有害事象を低減する方法
JP2012187515A Withdrawn JP2012229275A (ja) 2005-12-02 2012-08-28 ピルフェニドン療法に付随する有害事象を低減する方法
JP2015002231A Pending JP2015061888A (ja) 2005-12-02 2015-01-08 ピルフェニドン療法に付随する有害事象を低減する方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2012187515A Withdrawn JP2012229275A (ja) 2005-12-02 2012-08-28 ピルフェニドン療法に付随する有害事象を低減する方法
JP2015002231A Pending JP2015061888A (ja) 2005-12-02 2015-01-08 ピルフェニドン療法に付随する有害事象を低減する方法

Country Status (13)

Country Link
US (1) US20070203202A1 (cg-RX-API-DMAC7.html)
EP (2) EP2316453B1 (cg-RX-API-DMAC7.html)
JP (3) JP5175740B2 (cg-RX-API-DMAC7.html)
AT (1) ATE497766T1 (cg-RX-API-DMAC7.html)
CA (1) CA2631646C (cg-RX-API-DMAC7.html)
CY (1) CY1111355T1 (cg-RX-API-DMAC7.html)
DE (1) DE602006020070D1 (cg-RX-API-DMAC7.html)
DK (1) DK1965797T3 (cg-RX-API-DMAC7.html)
ES (2) ES2565190T3 (cg-RX-API-DMAC7.html)
PL (1) PL1965797T3 (cg-RX-API-DMAC7.html)
PT (1) PT1965797E (cg-RX-API-DMAC7.html)
SI (1) SI1965797T1 (cg-RX-API-DMAC7.html)
WO (1) WO2007064738A1 (cg-RX-API-DMAC7.html)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070203202A1 (en) 2005-12-02 2007-08-30 Robinson Cynthia Y Methods of reducing adverse events associated with pirfenidone therapy
WO2008077068A1 (en) * 2006-12-18 2008-06-26 Intermune, Inc. Method of providing pirfenidone therapy to a patient
US20080287508A1 (en) * 2007-05-18 2008-11-20 Intermune, Inc. Altering pharmacokinetics of pirfenidone therapy
WO2008157786A1 (en) 2007-06-20 2008-12-24 Auspex Pharmaceutical, Inc. Substituted n-aryl pyridinones as fibrotic inhibitors
US7635707B1 (en) 2008-11-10 2009-12-22 Intermune, Inc. Pirfenidone treatment for patients with atypical liver function
US7566729B1 (en) 2008-11-10 2009-07-28 Intermune, Inc. Modifying pirfenidone treatment for patients with atypical liver function
EP2389227A4 (en) * 2009-01-26 2012-08-08 Intermune Inc METHOD FOR THE TREATMENT OF ACUTE MYOCARDINE CARDS AND ASSOCIATED ILLNESSES THEREOF
US7816383B1 (en) 2009-12-04 2010-10-19 Intermune, Inc. Methods of administering pirfenidone therapy
US8084475B2 (en) 2009-12-04 2011-12-27 Intermune, Inc. Pirfenidone therapy and inducers of cytochrome P450
US10105356B2 (en) 2011-01-31 2018-10-23 Avalyn Pharma Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
HUE058753T2 (hu) 2011-01-31 2022-09-28 Avalyn Pharma Inc Aeroszol formájú pirfenidon- és piridon-analóg vegyületek és alkalmazásaik
CA2828895A1 (en) * 2011-03-08 2012-09-13 Auspex Pharamaceuticals, Inc. Substituted n-aryl pyridinones
MX2011007675A (es) * 2011-07-19 2012-07-11 Cell Therapy And Technology S A De C V Procedimiento para la fabricacion de una composicion farmaceutica en forma de tabletas de liberacion prolongada conteniendo pirfenidona y su aplicacion en la regresion de la insuficiencia renal cronica, contractura capsular mamaria y fibrosis hepatica humanas.
CN103917223B (zh) * 2011-09-14 2017-08-08 盐野义制药株式会社 供吸入的药用组合物
CA2819967C (en) 2012-08-31 2016-03-22 Intermune, Inc. Use of pirfenidone concomitantly with ciprofloxacin
HK1220133A1 (zh) 2013-03-15 2017-04-28 Intermune, Inc. 改善微血管完整性的方法
AU2015204558B2 (en) 2014-01-10 2020-04-30 Avalyn Pharma Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
CA2937365C (en) 2016-03-29 2018-09-18 F. Hoffmann-La Roche Ag Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same
TWI745396B (zh) 2016-07-12 2021-11-11 日商鹽野義製藥股份有限公司 吸入用醫藥組成物
WO2021107060A1 (ja) * 2019-11-27 2021-06-03 塩野義製薬株式会社 ピルフェニドンの副作用を軽減するための医薬

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3839346A (en) * 1972-12-18 1974-10-01 Affiliated Med Res N-substituted pyridone and general method for preparing pyridones
US5310562A (en) 1989-11-22 1994-05-10 Margolin Solomon B Composition and method for reparation and prevention of fibrotic lesions
ATE452637T1 (de) 2001-01-29 2010-01-15 Shionogi & Co Arzneipräparat, das als wirkstoff 5-methyl-1- phenyl-2-(1h)-pyridon enthält
US20070032457A1 (en) * 2003-05-16 2007-02-08 Blatt Lawrence M Combination therapy for cancer treatment
US20070203202A1 (en) 2005-12-02 2007-08-30 Robinson Cynthia Y Methods of reducing adverse events associated with pirfenidone therapy

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