JP2009517695A - バイオセンサー表面上での抗原のリアルタイム結合解析 - Google Patents
バイオセンサー表面上での抗原のリアルタイム結合解析 Download PDFInfo
- Publication number
- JP2009517695A JP2009517695A JP2008543421A JP2008543421A JP2009517695A JP 2009517695 A JP2009517695 A JP 2009517695A JP 2008543421 A JP2008543421 A JP 2008543421A JP 2008543421 A JP2008543421 A JP 2008543421A JP 2009517695 A JP2009517695 A JP 2009517695A
- Authority
- JP
- Japan
- Prior art keywords
- phage
- biosensor
- antibody
- binding
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
- G01N33/567—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds utilising isolate of tissue or organ as binding agent
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6878—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in epitope analysis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/290,036 US7524625B2 (en) | 2000-10-30 | 2005-11-30 | Real time binding analysis of antigens on a biosensor surface |
| PCT/US2006/045684 WO2007064702A1 (en) | 2005-11-30 | 2006-11-29 | Real time binding analysis of antigens on a biosensor surface |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009517695A true JP2009517695A (ja) | 2009-04-30 |
| JP2009517695A5 JP2009517695A5 (enExample) | 2010-01-21 |
Family
ID=37865867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008543421A Pending JP2009517695A (ja) | 2005-11-30 | 2006-11-29 | バイオセンサー表面上での抗原のリアルタイム結合解析 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7524625B2 (enExample) |
| EP (2) | EP2383580A1 (enExample) |
| JP (1) | JP2009517695A (enExample) |
| CN (1) | CN101336376A (enExample) |
| AU (1) | AU2006320660A1 (enExample) |
| CA (1) | CA2632055A1 (enExample) |
| NZ (1) | NZ569311A (enExample) |
| WO (1) | WO2007064702A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013128614A1 (ja) * | 2012-03-01 | 2013-09-06 | 日本精工株式会社 | 標的物質検出装置及び標的物質検出方法 |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8111401B2 (en) * | 1999-11-05 | 2012-02-07 | Robert Magnusson | Guided-mode resonance sensors employing angular, spectral, modal, and polarization diversity for high-precision sensing in compact formats |
| US7167615B1 (en) | 1999-11-05 | 2007-01-23 | Board Of Regents, The University Of Texas System | Resonant waveguide-grating filters and sensors and methods for making and using same |
| US7575939B2 (en) | 2000-10-30 | 2009-08-18 | Sru Biosystems, Inc. | Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements |
| US7524625B2 (en) * | 2000-10-30 | 2009-04-28 | Sru Biosystems, Inc. | Real time binding analysis of antigens on a biosensor surface |
| US7371562B2 (en) * | 2000-10-30 | 2008-05-13 | Sru Biosystems, Inc. | Guided mode resonant filter biosensor using a linear grating surface structure |
| AU2006236090B2 (en) * | 2000-10-30 | 2008-01-03 | Sru Biosystems, Inc. | A label-free high-throughput optical technique for detecting biomolecular interactions |
| US7094595B2 (en) | 2000-10-30 | 2006-08-22 | Sru Biosystems, Inc. | Label-free high-throughput optical technique for detecting biomolecular interactions |
| US7927822B2 (en) | 2002-09-09 | 2011-04-19 | Sru Biosystems, Inc. | Methods for screening cells and antibodies |
| US7309614B1 (en) | 2002-12-04 | 2007-12-18 | Sru Biosystems, Inc. | Self-referencing biodetection method and patterned bioassays |
| US8298780B2 (en) | 2003-09-22 | 2012-10-30 | X-Body, Inc. | Methods of detection of changes in cells |
| US20090218514A1 (en) * | 2004-12-10 | 2009-09-03 | Koninklijke Philips Electronics, N.V. | Multi-spot investigation apparatus |
| JP4783422B2 (ja) * | 2005-04-12 | 2011-09-28 | エス アール ユー バイオシステムズ,インコーポレイテッド | プロテオリピド膜及び脂質膜バイオセンサー |
| CA2693700A1 (en) | 2007-07-11 | 2009-01-15 | Sru Biosystems, Inc. | Methods for identifying modulators of ion channels |
| US9134307B2 (en) | 2007-07-11 | 2015-09-15 | X-Body, Inc. | Method for determining ion channel modulating properties of a test reagent |
| US8257936B2 (en) | 2008-04-09 | 2012-09-04 | X-Body Inc. | High resolution label free analysis of cellular properties |
| JP2011527573A (ja) * | 2008-07-11 | 2011-11-04 | エス アール ユー バイオシステムズ,インコーポレイテッド | イオンチャネルの調節因子を同定する方法 |
| KR101165720B1 (ko) * | 2008-11-18 | 2012-07-18 | 한국전자통신연구원 | 휴대용 광바이오 센서 측정 장치 및 그 측정 방법 |
| KR101123641B1 (ko) | 2008-12-31 | 2012-03-20 | 키스트 유럽 에프게엠베하 | 검출 물질에 특이적으로 반응할 수 있는 분자 인지 물질이 진열된 박테리오파아지의 제조 방법 및 상기 제조 방법으로제조된 박테리오파아지를 미량 검출물을 검출하는데 활용하는 방법 및 상기 박테리오파아지를 이용한 질량 분석장치 |
| KR101123640B1 (ko) | 2008-12-31 | 2012-04-19 | 키스트 유럽 에프게엠베하 | 전기 전도성을 지니게 하는 박테리오파아지의 제조 방법 및상기 제조 방법으로 제조된 박테리오파아지 및 상기 박테리오파아지를 분자 인지 센서로 이용하는 방법 및 상기박테리오파아지를 이용한 분자 인지 센서 |
| US20100273185A1 (en) * | 2009-04-27 | 2010-10-28 | Sru Biosystems, Inc. | Detection of Biased Agonist Activation |
| WO2010132890A1 (en) * | 2009-05-15 | 2010-11-18 | Sru Biosystems, Inc | Detection of changes in cell populations and mixed cell populations |
| US8525237B1 (en) * | 2010-10-04 | 2013-09-03 | The Regents Of The University Of California | Electrically conductive polymer nanowires with incorporated viruses |
| CN103728447B (zh) * | 2014-01-03 | 2016-07-13 | 北京纳晶生物科技有限公司 | 可控量子点位点特异性桥接偶联的抗体标记方法及其应用 |
| US9903816B2 (en) * | 2014-12-02 | 2018-02-27 | Infineon Technologies Ag | Photonic crystal sensor structure and a method for manufacturing the same |
| WO2017136187A2 (en) * | 2016-02-01 | 2017-08-10 | Micro Detect, Inc. | Uv solid state detection and methods therefor |
| US11740399B2 (en) * | 2018-02-06 | 2023-08-29 | Raytheon Company | Low cost dispersive optical elements |
| US11686013B2 (en) | 2018-02-23 | 2023-06-27 | Meso Scale Technologies, Llc. | Methods of screening antigen-binding molecules by normalizing for the concentration of antigen-binding molecule |
| CN108956983B (zh) * | 2018-05-07 | 2021-05-07 | 西北工业大学 | 一种以烟草花叶病毒为模板的微传感器可控阵列化制备方法 |
| WO2023039342A1 (en) * | 2021-09-08 | 2023-03-16 | Arizona Board Of Regents On Behalf Of Arizona State University | Charge-sensitive optical detection of binding kinetics between phage displayed peptide ligands and protein targets |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05211871A (ja) * | 1992-01-31 | 1993-08-24 | Rikagaku Kenkyusho | 領域指定突然変異導入法 |
| WO2001079559A1 (en) * | 2000-04-18 | 2001-10-25 | Wayne State University | System to detect protein-protein interactions |
| JP2002526111A (ja) * | 1998-10-07 | 2002-08-20 | ストライカー・コーポレーション | 形態形成タンパク質を含むTGF−βスーパーファミリー変異体メンバー |
| WO2004036177A2 (en) * | 2002-10-15 | 2004-04-29 | Regents Of The University Of Minnesota | Assays to detect or quantify bacterial or viral pathogens and contaminants |
| US20040229215A1 (en) * | 2003-03-04 | 2004-11-18 | Auburn University | Methods of forming monolayers of phage-derived products and uses thereof |
| WO2005001475A2 (en) * | 2003-04-10 | 2005-01-06 | Kent Voorhees | Apparatus and method for detecting microscopic living organisms using bacteriophage |
| JP2005535870A (ja) * | 2001-11-07 | 2005-11-24 | オーバーン ユニバーシティ | ファージリガンドセンサーデバイスおよびその使用 |
Family Cites Families (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8423204D0 (en) | 1984-09-14 | 1984-10-17 | Comtech Res Unit | Assay technique and equipment |
| US4815843A (en) | 1985-05-29 | 1989-03-28 | Oerlikon-Buhrle Holding Ag | Optical sensor for selective detection of substances and/or for the detection of refractive index changes in gaseous, liquid, solid and porous samples |
| SE8804074D0 (sv) * | 1988-11-10 | 1988-11-10 | Pharmacia Ab | Sensorenhet och dess anvaendning i biosensorsystem |
| SE8902043L (sv) * | 1988-11-10 | 1990-05-11 | Pharmacia Ab | Foerfarande foer karakterisering av makromolekyler |
| US5216680A (en) | 1991-07-11 | 1993-06-01 | Board Of Regents, The University Of Texas System | Optical guided-mode resonance filter |
| GB9314991D0 (en) | 1993-07-20 | 1993-09-01 | Sandoz Ltd | Mechanical device |
| WO1996038726A1 (en) | 1995-05-30 | 1996-12-05 | Ecole Polytechnique Federale De Lausanne (Epfl) | Covalently immobilized phospholipid bilayers on solid surfaces |
| GB9602542D0 (en) | 1996-02-08 | 1996-04-10 | Fisons Plc | Analytical device |
| US5666197A (en) | 1996-08-21 | 1997-09-09 | Polaroid Corporation | Apparatus and methods employing phase control and analysis of evanescent illumination for imaging and metrology of subwavelength lateral surface topography |
| JP2001504213A (ja) | 1996-08-29 | 2001-03-27 | ツェプトゼンス アクチエンゲゼルシャフト | 化学的/生化学的な光センサ |
| EP1443320A3 (de) | 1997-09-10 | 2005-02-02 | Artificial Sensing Instruments ASI AG | Sensorchip zur Charakterisierung einer chemischen und/oder biochemischen Substanz |
| US6346376B1 (en) | 1998-06-03 | 2002-02-12 | Centre Suisse D'electronique Et De Mictotechnique Sa | Optical sensor unit and procedure for the ultrasensitive detection of chemical or biochemical analytes |
| US6684007B2 (en) | 1998-10-09 | 2004-01-27 | Fujitsu Limited | Optical coupling structures and the fabrication processes |
| DE69933193T2 (de) | 1999-02-25 | 2007-08-02 | C.S.E.M. Centre Suisse D'electronique Et De Microtechnique S.A. | Integrierter optischer Sensor und Verfahren zum integrierten optischen Nachweis einer Substanz |
| EP1192448B1 (en) | 1999-07-05 | 2006-09-27 | Novartis AG | Process of using a sensor platform |
| US6771376B2 (en) | 1999-07-05 | 2004-08-03 | Novartis Ag | Sensor platform, apparatus incorporating the platform, and process using the platform |
| ATE244883T1 (de) | 1999-09-15 | 2003-07-15 | Suisse Electronique Microtech | Integriert-optischer sensor |
| US6541071B1 (en) | 2000-03-23 | 2003-04-01 | Corning Incorporated | Method for fabricating supported bilayer-lipid membranes |
| WO2001092870A2 (de) | 2000-06-02 | 2001-12-06 | Zeptosens Ag | Kit und verfahren zur multianalytbestimmung |
| US7312043B2 (en) | 2000-07-10 | 2007-12-25 | Vertex Pharmaceuticals (San Diego) Llc | Ion channel assay methods |
| US20040219619A1 (en) | 2000-07-21 | 2004-11-04 | Ester Fernandez-Salas | Methods of identifying compounds that alter toxin persistence and/or protease activity |
| US7264973B2 (en) | 2000-10-30 | 2007-09-04 | Sru Biosystems, Inc. | Label-free methods for performing assays using a colorimetric resonant optical biosensor |
| US7371562B2 (en) | 2000-10-30 | 2008-05-13 | Sru Biosystems, Inc. | Guided mode resonant filter biosensor using a linear grating surface structure |
| US20030113766A1 (en) | 2000-10-30 | 2003-06-19 | Sru Biosystems, Llc | Amine activated colorimetric resonant biosensor |
| DE60111408T2 (de) | 2000-10-30 | 2006-05-11 | Ato Findley Inc., Wauwatosa | Heissschmelzklebezusammensetzung mit nässeindikator |
| US7142296B2 (en) | 2000-10-30 | 2006-11-28 | Sru Biosystems, Inc. | Method and apparatus for detecting biomolecular interactions |
| US7217574B2 (en) | 2000-10-30 | 2007-05-15 | Sru Biosystems, Inc. | Method and apparatus for biosensor spectral shift detection |
| US7575939B2 (en) | 2000-10-30 | 2009-08-18 | Sru Biosystems, Inc. | Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements |
| US7306827B2 (en) | 2000-10-30 | 2007-12-11 | Sru Biosystems, Inc. | Method and machine for replicating holographic gratings on a substrate |
| US7070987B2 (en) | 2000-10-30 | 2006-07-04 | Sru Biosystems, Inc. | Guided mode resonant filter biosensor using a linear grating surface structure |
| US7524625B2 (en) | 2000-10-30 | 2009-04-28 | Sru Biosystems, Inc. | Real time binding analysis of antigens on a biosensor surface |
| US7153702B2 (en) | 2000-10-30 | 2006-12-26 | Sru Biosystems, Inc. | Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor |
| US6951715B2 (en) | 2000-10-30 | 2005-10-04 | Sru Biosystems, Inc. | Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements |
| US7023544B2 (en) | 2000-10-30 | 2006-04-04 | Sru Biosystems, Inc. | Method and instrument for detecting biomolecular interactions |
| US20030092075A1 (en) | 2000-10-30 | 2003-05-15 | Sru Biosystems, Llc | Aldehyde chemical surface activation processes and test methods for colorimetric resonant sensors |
| US7101660B2 (en) | 2000-10-30 | 2006-09-05 | Sru Biosystems, Inc. | Method for producing a colorimetric resonant reflection biosensor on rigid surfaces |
| US7202076B2 (en) | 2000-10-30 | 2007-04-10 | Sru Biosystems, Inc. | Label-free high-throughput optical technique for detecting biomolecular interactions |
| US7094595B2 (en) | 2000-10-30 | 2006-08-22 | Sru Biosystems, Inc. | Label-free high-throughput optical technique for detecting biomolecular interactions |
| US7175980B2 (en) | 2000-10-30 | 2007-02-13 | Sru Biosystems, Inc. | Method of making a plastic colorimetric resonant biosensor device with liquid handling capabilities |
| CA2453528C (en) | 2001-08-01 | 2011-07-26 | Cellomics, Inc. | Novel fusion proteins and assays for molecular binding |
| US7927822B2 (en) | 2002-09-09 | 2011-04-19 | Sru Biosystems, Inc. | Methods for screening cells and antibodies |
| US20040091397A1 (en) | 2002-11-07 | 2004-05-13 | Corning Incorporated | Multiwell insert device that enables label free detection of cells and other objects |
| US7309614B1 (en) | 2002-12-04 | 2007-12-18 | Sru Biosystems, Inc. | Self-referencing biodetection method and patterned bioassays |
| US7497992B2 (en) | 2003-05-08 | 2009-03-03 | Sru Biosystems, Inc. | Detection of biochemical interactions on a biosensor using tunable filters and tunable lasers |
| US8298780B2 (en) | 2003-09-22 | 2012-10-30 | X-Body, Inc. | Methods of detection of changes in cells |
| AU2004290375A1 (en) | 2003-11-06 | 2005-05-26 | Sru Biosystems, Inc. | High-density amine-functionalized surface |
| US6990259B2 (en) | 2004-03-29 | 2006-01-24 | Sru Biosystems, Inc. | Photonic crystal defect cavity biosensor |
| EP1769230A2 (en) | 2004-06-28 | 2007-04-04 | SRU Biosystems, Inc. | Integration of direct binding sensors with mass spectrometry for functional and structural characterization of molecules |
| DE102004052510A1 (de) | 2004-10-21 | 2006-04-27 | Wilhelm Stahlecker Gmbh | Luftdüsenspinnmaschine |
| US7803619B2 (en) | 2004-11-24 | 2010-09-28 | Geneprotech, Inc. | Embryoid body-based screen |
| JP4783422B2 (ja) | 2005-04-12 | 2011-09-28 | エス アール ユー バイオシステムズ,インコーポレイテッド | プロテオリピド膜及び脂質膜バイオセンサー |
| US7162125B1 (en) | 2005-06-23 | 2007-01-09 | Sru Biosystems, Inc. | Optimized grating based biosensor and substrate combination |
| US7197198B2 (en) | 2005-06-23 | 2007-03-27 | Sru Biosystems, Inc. | Biosensor substrate structure for reducing the effects of optical interference |
| US7479404B2 (en) | 2005-07-08 | 2009-01-20 | The Board Of Trustees Of The University Of Illinois | Photonic crystal biosensor structure and fabrication method |
| US7521769B2 (en) | 2005-07-08 | 2009-04-21 | Sru Biosystems, Inc. | Photonic crystal biosensor structure and fabrication method |
| US7483127B1 (en) | 2005-08-08 | 2009-01-27 | Sru Biosystems, Inc. | Method and apparatus for generating an image of biomolecular sensor target area |
| US7790406B2 (en) | 2005-08-11 | 2010-09-07 | Sru Biosystems, Inc | Grating-based sensor combining label-free binding detection and fluorescence amplification and readout system for sensor |
| KR101006793B1 (ko) | 2005-08-11 | 2011-01-10 | 에스알유 바이오시스템즈, 인코포레이티드 | 라벨 없는 바인딩 검출 및 형광 증폭과 조합된 격자-기반센서 및 센서를 위한 판독 시스템 |
| WO2008008247A2 (en) | 2006-07-07 | 2008-01-17 | The Board Of Trustees Of The University Of Illinois | Near ultraviolet-wavelength photonic-crystal biosensor with enhanced surface to bulk sensitivity ratio |
| EP2087353A2 (en) | 2006-10-31 | 2009-08-12 | SRU Biosystems, Inc. | Method for blocking non-specific protein binding on a functionalized surface |
| WO2008060415A1 (en) | 2006-11-09 | 2008-05-22 | The Board Of Trustees Of The University Of Illinois | Photonic crystal sensors with integrated fluid containment structure |
| US7628085B2 (en) | 2006-11-17 | 2009-12-08 | Sru Biosystems, Inc. | Simultaneous aspirator and dispenser for multiwell plates and similar devices |
| US20080240543A1 (en) | 2007-03-30 | 2008-10-02 | Wolfgang Ernst Gustav Budach | Calibration and normalization method for biosensors |
| CA2683082A1 (en) | 2007-04-19 | 2008-10-30 | Sru Biosystems, Inc. | Method for employing a biosensor to detect small molecules that bind directly to immobilized targets |
| CA2693700A1 (en) | 2007-07-11 | 2009-01-15 | Sru Biosystems, Inc. | Methods for identifying modulators of ion channels |
| US9134307B2 (en) | 2007-07-11 | 2015-09-15 | X-Body, Inc. | Method for determining ion channel modulating properties of a test reagent |
| US8268637B2 (en) | 2008-01-11 | 2012-09-18 | The Board Of Trustees Of The University Of Illinois | Label-free biosensors based upon distributed feedback laser |
| US20090213910A1 (en) * | 2008-02-25 | 2009-08-27 | Grant Stephen J | Code Power Estimation for MIMO Signals |
| WO2009114133A1 (en) | 2008-03-10 | 2009-09-17 | The J. David Gladstone Institutes | Cells and assays for use in detecting long qt syndrome |
| US8257936B2 (en) | 2008-04-09 | 2012-09-04 | X-Body Inc. | High resolution label free analysis of cellular properties |
| US20100015721A1 (en) | 2008-06-04 | 2010-01-21 | Sru Biosystems, Inc. | Detection of Promiscuous Small Submicrometer Aggregates |
| US20100008826A1 (en) | 2008-07-10 | 2010-01-14 | Sru Biosystems, Inc. | Biosensors featuring confinement of deposited material and intra-well self-referencing |
| JP2011527573A (ja) | 2008-07-11 | 2011-11-04 | エス アール ユー バイオシステムズ,インコーポレイテッド | イオンチャネルの調節因子を同定する方法 |
| WO2010087806A1 (en) | 2009-02-02 | 2010-08-05 | Sru Biosystems, Inc | Efficient optical arrangement for illumination and detection of label-free biosensors and method to reduce interference fringes in label-free imaging |
| WO2010132890A1 (en) | 2009-05-15 | 2010-11-18 | Sru Biosystems, Inc | Detection of changes in cell populations and mixed cell populations |
-
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- 2005-11-30 US US11/290,036 patent/US7524625B2/en not_active Expired - Lifetime
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2006
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- 2006-11-29 EP EP11170906A patent/EP2383580A1/en not_active Withdrawn
- 2006-11-29 EP EP06838572A patent/EP1960791A1/en not_active Withdrawn
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- 2006-11-29 JP JP2008543421A patent/JP2009517695A/ja active Pending
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- 2006-11-29 WO PCT/US2006/045684 patent/WO2007064702A1/en not_active Ceased
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Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05211871A (ja) * | 1992-01-31 | 1993-08-24 | Rikagaku Kenkyusho | 領域指定突然変異導入法 |
| JP2002526111A (ja) * | 1998-10-07 | 2002-08-20 | ストライカー・コーポレーション | 形態形成タンパク質を含むTGF−βスーパーファミリー変異体メンバー |
| WO2001079559A1 (en) * | 2000-04-18 | 2001-10-25 | Wayne State University | System to detect protein-protein interactions |
| JP2005535870A (ja) * | 2001-11-07 | 2005-11-24 | オーバーン ユニバーシティ | ファージリガンドセンサーデバイスおよびその使用 |
| WO2004036177A2 (en) * | 2002-10-15 | 2004-04-29 | Regents Of The University Of Minnesota | Assays to detect or quantify bacterial or viral pathogens and contaminants |
| US20040229215A1 (en) * | 2003-03-04 | 2004-11-18 | Auburn University | Methods of forming monolayers of phage-derived products and uses thereof |
| WO2005001475A2 (en) * | 2003-04-10 | 2005-01-06 | Kent Voorhees | Apparatus and method for detecting microscopic living organisms using bacteriophage |
Non-Patent Citations (3)
| Title |
|---|
| JPN5008020027; CEKAITE LINA: PROTEOMICS V4 N9, 200409, P2572-2582 * |
| JPN5008020028; SUN W: JOURNAL OF INDUSTRIAL MICROBIOLOGY AND BIOTECHNOLOGY V25 N5, 200011, P273-275 * |
| JPN5008020029; WAN JIEHUI: PROCEEDINGS OF THE FOURTH IEEE CONFERENCE ON SENSORS V2005, 20051103, P1308-1311 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013128614A1 (ja) * | 2012-03-01 | 2013-09-06 | 日本精工株式会社 | 標的物質検出装置及び標的物質検出方法 |
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| CA2632055A1 (en) | 2007-06-07 |
| CN101336376A (zh) | 2008-12-31 |
| NZ569311A (en) | 2011-10-28 |
| US20090176658A1 (en) | 2009-07-09 |
| US20060148100A1 (en) | 2006-07-06 |
| EP1960791A1 (en) | 2008-08-27 |
| EP2383580A1 (en) | 2011-11-02 |
| US8293542B2 (en) | 2012-10-23 |
| AU2006320660A1 (en) | 2007-06-07 |
| US7524625B2 (en) | 2009-04-28 |
| WO2007064702A1 (en) | 2007-06-07 |
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