JP2009517480A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009517480A5 JP2009517480A5 JP2008543418A JP2008543418A JP2009517480A5 JP 2009517480 A5 JP2009517480 A5 JP 2009517480A5 JP 2008543418 A JP2008543418 A JP 2008543418A JP 2008543418 A JP2008543418 A JP 2008543418A JP 2009517480 A5 JP2009517480 A5 JP 2009517480A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- enantiomer
- group
- compounds
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74131505P | 2005-12-01 | 2005-12-01 | |
| US60/741,315 | 2005-12-01 | ||
| US84136606P | 2006-08-30 | 2006-08-30 | |
| US60/841,366 | 2006-08-30 | ||
| PCT/US2006/045673 WO2007064697A1 (en) | 2005-12-01 | 2006-11-30 | Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009517480A JP2009517480A (ja) | 2009-04-30 |
| JP2009517480A5 true JP2009517480A5 (enExample) | 2013-01-17 |
| JP5302005B2 JP5302005B2 (ja) | 2013-10-02 |
Family
ID=37776574
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008543418A Expired - Fee Related JP5302005B2 (ja) | 2005-12-01 | 2006-11-30 | セロトニン作動性および/またはノルエピネフリン作動性の活性を有する置換フェネチルアミン |
Country Status (18)
| Country | Link |
|---|---|
| US (9) | US7456317B2 (enExample) |
| EP (2) | EP2998288B1 (enExample) |
| JP (1) | JP5302005B2 (enExample) |
| KR (1) | KR101068180B1 (enExample) |
| AU (1) | AU2006320655A1 (enExample) |
| BR (1) | BRPI0620587A2 (enExample) |
| CA (1) | CA2631581C (enExample) |
| DK (1) | DK1954669T3 (enExample) |
| EA (1) | EA200801488A1 (enExample) |
| ES (1) | ES2549079T3 (enExample) |
| HU (1) | HUE027865T2 (enExample) |
| IL (1) | IL191847A0 (enExample) |
| MA (1) | MA30088B1 (enExample) |
| NZ (1) | NZ568720A (enExample) |
| PL (1) | PL1954669T3 (enExample) |
| PT (1) | PT1954669E (enExample) |
| SI (1) | SI1954669T1 (enExample) |
| WO (1) | WO2007064697A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100076087A1 (en) * | 2005-10-06 | 2010-03-25 | Auspex Pharmaceuticals, Inc. | Methods of reduction of interpatient variability |
| EP2998288B1 (en) | 2005-12-01 | 2022-08-24 | ACADIA Pharmaceuticals Inc. | Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity |
| US7968874B2 (en) * | 2006-08-31 | 2011-06-28 | Nippon Steel Chemical Co., Ltd. | Organic electroluminescent device material and organic electroluminescent device |
| CA2680912C (en) | 2007-03-15 | 2017-11-14 | Auspex Pharmaceuticals, Inc. | Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity |
| US7767860B2 (en) | 2007-09-06 | 2010-08-03 | Auspex Pharmaceuticals, Inc | Substituted amino alcohols |
| US20110053968A1 (en) | 2009-06-09 | 2011-03-03 | Auspex Pharmaceuticals, Inc. | Aminopyrimidine inhibitors of tyrosine kinase |
| WO2010147830A2 (en) * | 2009-06-15 | 2010-12-23 | Auspex Pharmaceuticals, Inc. | Aminothiazole modulators of beta-3-adrenoreceptor |
| CN102639700A (zh) | 2009-09-30 | 2012-08-15 | 哈佛大学校长及研究员协会 | 通过调节自噬增强基因产物调节自噬的方法 |
| LT3135656T (lt) | 2011-06-20 | 2019-04-25 | H. Lundbeck A/S | Deuterinti 1-piperazin-3-fenilindanai, skirti šizofrenijos gydymui |
| MX2016010213A (es) | 2014-02-07 | 2017-04-13 | Auspex Pharmaceuticals Inc | Formulaciones farmaceuticas novedosas. |
| CN104059030B (zh) | 2014-05-30 | 2016-05-04 | 镇江圣安医药有限公司 | [(苯硫烷基)-苯基]哌嗪的衍生物及其药物组合物和用途 |
| WO2017079102A1 (en) * | 2015-11-03 | 2017-05-11 | Albert Einstein College Of Medicine, Inc. | Use of 13c derivatization reagents for gas or liquid chromatography-mass spectroscopy chemical identification and quantification |
| CN113056457B (zh) | 2018-12-03 | 2025-06-20 | H.隆德贝克有限公司 | 用于治疗cns疾病的前药 |
| IL312785B2 (en) | 2020-05-19 | 2026-06-01 | Cybin Irl Ltd | Deuterated tryptamine derivatives and methods of use |
| WO2024194352A1 (en) | 2023-03-23 | 2024-09-26 | Glaxosmithkline Intellectual Property (No.3) Limited | Deuterated p2x3 modulators |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4069346A (en) | 1977-02-14 | 1978-01-17 | The Dow Chemical Company | Compositions and methods for anesthetizing an animal using deuterated analogues of halothane and chloroform |
| IE56324B1 (en) * | 1982-12-13 | 1991-06-19 | American Home Prod | Phenethylamine derivatives and intermediates therefor |
| US4535186A (en) | 1983-04-19 | 1985-08-13 | American Home Products Corporation | 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives |
| SE9002043D0 (sv) | 1990-06-07 | 1990-06-07 | Astra Ab | Improved method for synthesis |
| US6440457B1 (en) | 1993-05-27 | 2002-08-27 | Alza Corporation | Method of administering antidepressant dosage form |
| DK0639374T3 (da) | 1993-06-28 | 2002-05-06 | American Home Prod | Nye behandlingsmetoder ved anvendelse af phenethylderivater |
| TW344661B (en) | 1993-11-24 | 1998-11-11 | Lilly Co Eli | Pharmaceutical composition for treatment of incontinence |
| US6221335B1 (en) | 1994-03-25 | 2001-04-24 | Isotechnika, Inc. | Method of using deuterated calcium channel blockers |
| US6334997B1 (en) | 1994-03-25 | 2002-01-01 | Isotechnika, Inc. | Method of using deuterated calcium channel blockers |
| KR100477070B1 (ko) | 1994-03-25 | 2006-04-21 | 이소테크니카 인코포레이티드 | 중수소화작용에의한의약품의효능강화법 |
| US20030215507A1 (en) | 1996-03-25 | 2003-11-20 | Wyeth | Extended release formulation |
| US6274171B1 (en) | 1996-03-25 | 2001-08-14 | American Home Products Corporation | Extended release formulation of venlafaxine hydrochloride |
| US6342507B1 (en) | 1997-09-05 | 2002-01-29 | Isotechnika, Inc. | Deuterated rapamycin compounds, method and uses thereof |
| US6884429B2 (en) | 1997-09-05 | 2005-04-26 | Isotechnika International Inc. | Medical devices incorporating deuterated rapamycin for controlled delivery thereof |
| DE69832984T2 (de) | 1997-10-08 | 2006-09-21 | Isotechnika, Inc., Edmonton | DEUTERIERtE und undeuterierte CYCLOSPORIN-ANALOGA UND IHRE VERWENDUNG ALS IMMUNMODULIERENDE AGENtIEN |
| US6579899B1 (en) | 1998-07-16 | 2003-06-17 | Massachusetts Institute Of Technology | Composition for treatment of stress |
| US6333342B1 (en) | 1998-11-04 | 2001-12-25 | Isotechnika, Inc | Methods of pharmacological treatment using S(−) amlodipine |
| US6197828B1 (en) * | 1998-12-01 | 2001-03-06 | Sepracor, Inc. | Derivatives of (+)-venlafaxine and methods of preparing and using the same |
| US6440710B1 (en) * | 1998-12-10 | 2002-08-27 | The Scripps Research Institute | Antibody-catalyzed deuteration, tritiation, dedeuteration or detritiation of carbonyl compounds |
| US6071918A (en) * | 1999-07-21 | 2000-06-06 | Dupont Pharmaceuticals Company | Combination of an opioid antagonist and a selective serotonin reuptake inhibitor for treatment of alcoholism and alcohol dependence |
| AR025110A1 (es) | 1999-08-13 | 2002-11-06 | Vela Pharmaceuticals Inc | Metodos y composiciones para tratar o prevenir alteraciones del sueno y enfermedades asociadas usando dosis muy bajas de ciclobenzaprina |
| US20050233459A1 (en) * | 2003-11-26 | 2005-10-20 | Melker Richard J | Marker detection method and apparatus to monitor drug compliance |
| DK1104760T3 (da) | 1999-12-03 | 2003-06-30 | Pfizer Prod Inc | Sulfamoylheteroarylpyrazolforbindelser som anti-inflammatoriske/analgetiske midler |
| EP1134290A3 (en) * | 2000-03-14 | 2004-01-02 | Pfizer Products Inc. | Pharmacophore models for the identification of the CYP2D6 inhibitory potency of selective serotonin reuptake inhibitors |
| US20020183553A1 (en) | 2000-10-19 | 2002-12-05 | Ben-Zion Dolitzky | Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof |
| US20050054942A1 (en) | 2002-01-22 | 2005-03-10 | Melker Richard J. | System and method for therapeutic drug monitoring |
| EA011451B1 (ru) * | 2001-02-12 | 2009-04-28 | Уайт | Новая соль сукцинат о-десметилвенлафаксина |
| AU2002303427A1 (en) | 2001-04-24 | 2002-11-05 | East Carolina University | Compositions and formulations with a non-glucocorticoid steroid and/or a ubiquinone and kit for treatment of respiratory and lung disease |
| IL146462A (en) | 2001-11-13 | 2015-02-26 | Lycored Bio Ltd | Prolonged-release preparations containing as an active compound and analapaxin hydrochloride |
| TW200413273A (en) * | 2002-11-15 | 2004-08-01 | Wako Pure Chem Ind Ltd | Heavy hydrogenation method of heterocyclic rings |
| KR20060121178A (ko) | 2003-12-12 | 2006-11-28 | 일라이 릴리 앤드 캄파니 | 일과성 전신 열감, 충동 조절 장애 및 일반적인 의학상태로 인한 인격 변화 치료용 선택적 노르에피네프린재흡수 억제제 |
| US20050181071A1 (en) | 2004-02-18 | 2005-08-18 | Binder Michael R. | Method for the treatment of clinical depression |
| JP5036532B2 (ja) * | 2004-04-08 | 2012-09-26 | アルメテオン、インコーポレイテッド | 血液凝固疾患治療のための物質およびその方法 |
| US20050261278A1 (en) | 2004-05-21 | 2005-11-24 | Weiner David M | Selective serotonin receptor inverse agonists as therapeutics for disease |
| US20060069086A1 (en) | 2004-09-23 | 2006-03-30 | Alexander Michalow | Methods for regulating neurotransmitter systems by inducing counteradaptations |
| US20060135443A1 (en) | 2004-10-18 | 2006-06-22 | Bionaut Pharmaceuticals, Inc. | Use of Na*/K*-ATPase inhibitors and antagonists thereof |
| US20080033011A1 (en) * | 2005-07-29 | 2008-02-07 | Concert Pharmaceuticals Inc. | Novel benzo[d][1,3]-dioxol derivatives |
| US20100076087A1 (en) | 2005-10-06 | 2010-03-25 | Auspex Pharmaceuticals, Inc. | Methods of reduction of interpatient variability |
| WO2007052274A2 (en) * | 2005-11-06 | 2007-05-10 | Brain Watch Ltd. | Magnetic resonance imaging and spectroscopy means and methods thereof |
| EP2998288B1 (en) | 2005-12-01 | 2022-08-24 | ACADIA Pharmaceuticals Inc. | Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity |
| US7750168B2 (en) * | 2006-02-10 | 2010-07-06 | Sigma-Aldrich Co. | Stabilized deuteroborane-tetrahydrofuran complex |
| US20090312435A1 (en) | 2006-08-30 | 2009-12-17 | Auspex Pharmaceuticals, Inc | Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity |
| CA2680912C (en) | 2007-03-15 | 2017-11-14 | Auspex Pharmaceuticals, Inc. | Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity |
| US20080280991A1 (en) * | 2007-05-08 | 2008-11-13 | Auspex Pharmaceuticals, Inc. | Substituted naphthalenes |
| WO2009018169A1 (en) | 2007-07-27 | 2009-02-05 | Auspex Pharmaceuticals, Inc. | Substituted cyclohexanols |
| US20090069431A1 (en) | 2007-09-12 | 2009-03-12 | Protia, Llc | Deuterium-enriched milnacipran |
| US20090076162A1 (en) | 2007-09-17 | 2009-03-19 | Protia, Llc | Deuterium-enriched desvenlafaxine |
| US20100007087A1 (en) * | 2008-07-09 | 2010-01-14 | John Michael Pryke | Six fold game board and method of folding game board |
| WO2010028130A2 (en) | 2008-09-03 | 2010-03-11 | Concert Pharmaceuticals, Inc. | Antidepressant compounds |
-
2006
- 2006-11-30 EP EP15175770.5A patent/EP2998288B1/en not_active Not-in-force
- 2006-11-30 HU HUE06844628A patent/HUE027865T2/en unknown
- 2006-11-30 JP JP2008543418A patent/JP5302005B2/ja not_active Expired - Fee Related
- 2006-11-30 DK DK06844628.5T patent/DK1954669T3/en active
- 2006-11-30 EP EP06844628.5A patent/EP1954669B1/en not_active Not-in-force
- 2006-11-30 PL PL06844628T patent/PL1954669T3/pl unknown
- 2006-11-30 EA EA200801488A patent/EA200801488A1/ru unknown
- 2006-11-30 ES ES06844628.5T patent/ES2549079T3/es active Active
- 2006-11-30 NZ NZ568720A patent/NZ568720A/en not_active IP Right Cessation
- 2006-11-30 BR BRPI0620587-9A patent/BRPI0620587A2/pt not_active IP Right Cessation
- 2006-11-30 CA CA2631581A patent/CA2631581C/en active Active
- 2006-11-30 PT PT68446285T patent/PT1954669E/pt unknown
- 2006-11-30 AU AU2006320655A patent/AU2006320655A1/en not_active Abandoned
- 2006-11-30 SI SI200631981T patent/SI1954669T1/sl unknown
- 2006-11-30 KR KR1020087015962A patent/KR101068180B1/ko not_active Expired - Fee Related
- 2006-11-30 WO PCT/US2006/045673 patent/WO2007064697A1/en not_active Ceased
- 2006-11-30 US US11/565,451 patent/US7456317B2/en active Active
-
2008
- 2008-05-29 IL IL191847A patent/IL191847A0/en unknown
- 2008-06-26 MA MA31078A patent/MA30088B1/fr unknown
- 2008-09-19 US US12/234,318 patent/US8138226B2/en active Active
- 2008-09-19 US US12/234,236 patent/US9422225B2/en active Active
-
2014
- 2014-06-17 US US14/306,396 patent/US9458082B2/en active Active
-
2016
- 2016-07-08 US US15/205,491 patent/US20160318847A1/en not_active Abandoned
- 2016-08-23 US US15/244,575 patent/US20160361275A1/en not_active Abandoned
-
2017
- 2017-05-17 US US15/597,516 patent/US20180085327A1/en not_active Abandoned
-
2018
- 2018-05-09 US US15/975,570 patent/US20180256517A1/en not_active Abandoned
-
2019
- 2019-03-04 US US16/291,126 patent/US20200060995A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US8138226B2 (en) | Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity | |
| US20110130424A1 (en) | Substituted phenylpiperidines with serotoninergic activity and enhanced therapeutic properties | |
| US20110136914A1 (en) | Substituted aryloxypropylamines with serotoninergic and/or norepinephrinergic activity | |
| US20090312435A1 (en) | Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity | |
| CN101336226B (zh) | 具有5-羟色胺能活性和/或去甲肾上腺素能活性的取代的苯乙胺 | |
| US20100137244A1 (en) | Preparation and utility of hmg-coa reductase inhibitors | |
| HK1216635A1 (en) | Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity | |
| CN101360698A (zh) | 具有血清素源性活性和/或去甲肾上腺素能活性的取代芳氧基丙胺 | |
| HK1126751A (en) | Substituted aryloxypropylamines with serotoninergic and/or norepinephrinergic activity | |
| HK1125626B (en) | Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity | |
| HK1126774A (en) | Substituted phenylpiperidines with serotoninergic activity and enhanced therapeutic properties |