JP2009517386A5 - - Google Patents
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- Publication number
- JP2009517386A5 JP2009517386A5 JP2008542377A JP2008542377A JP2009517386A5 JP 2009517386 A5 JP2009517386 A5 JP 2009517386A5 JP 2008542377 A JP2008542377 A JP 2008542377A JP 2008542377 A JP2008542377 A JP 2008542377A JP 2009517386 A5 JP2009517386 A5 JP 2009517386A5
- Authority
- JP
- Japan
- Prior art keywords
- aag
- pharmaceutical suspension
- phosphatidylcholine
- ester
- block copolymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000007971 pharmaceutical suspension Substances 0.000 claims 8
- 150000002148 esters Chemical class 0.000 claims 5
- 238000009472 formulation Methods 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 5
- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 claims 5
- 229920001400 block copolymer Polymers 0.000 claims 4
- 229920001214 Polysorbate 60 Polymers 0.000 claims 3
- 235000014113 dietary fatty acids Nutrition 0.000 claims 3
- 239000000194 fatty acid Substances 0.000 claims 3
- 229930195729 fatty acid Natural products 0.000 claims 3
- 150000004665 fatty acids Chemical class 0.000 claims 3
- 239000002245 particle Substances 0.000 claims 3
- 239000000546 pharmaceutical excipient Substances 0.000 claims 3
- 239000004094 surface-active agent Substances 0.000 claims 3
- 150000001720 carbohydrates Chemical class 0.000 claims 2
- 229920002503 polyoxyethylene-polyoxypropylene Polymers 0.000 claims 2
- 229930006000 Sucrose Natural products 0.000 claims 1
- 239000012736 aqueous medium Substances 0.000 claims 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 claims 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims 1
- 229920000053 polysorbate 80 Polymers 0.000 claims 1
- 239000005720 sucrose Substances 0.000 claims 1
- 125000000185 sucrose group Chemical group 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73922505P | 2005-11-23 | 2005-11-23 | |
| US80952706P | 2006-05-30 | 2006-05-30 | |
| US11/595,005 US7648976B2 (en) | 2005-11-23 | 2006-11-08 | 17-allylamino-17-demethoxygeldanamycin polymorphs and formulations |
| PCT/US2006/044746 WO2007061878A2 (en) | 2005-11-23 | 2006-11-16 | 17-allylamino-17-demethoxygeldanamycin polymorphs and formulations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009517386A JP2009517386A (ja) | 2009-04-30 |
| JP2009517386A5 true JP2009517386A5 (https=) | 2010-01-07 |
Family
ID=38067791
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008542377A Abandoned JP2009517386A (ja) | 2005-11-23 | 2006-11-16 | １７−アリルアミノ−１７−デメトキシゲルダナマイシン多形体及び製剤 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7648976B2 (https=) |
| EP (1) | EP1951223A4 (https=) |
| JP (1) | JP2009517386A (https=) |
| KR (1) | KR20080089357A (https=) |
| AU (1) | AU2006318771A1 (https=) |
| BR (1) | BRPI0618873A2 (https=) |
| CA (1) | CA2629196A1 (https=) |
| WO (1) | WO2007061878A2 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090042847A1 (en) * | 2005-11-23 | 2009-02-12 | Kosan Biosciences Incorporated | 17-allylamino-17-demethoxygeldanamycin polymorphs and formulations |
| US20070167422A1 (en) * | 2006-01-18 | 2007-07-19 | Yu Kwok S | Pharmaceutical compositions comprising 17-allylamino-17-demethoxygeldanamycin |
| GB0612928D0 (en) * | 2006-06-29 | 2006-08-09 | Ucb Sa | Biological products |
| CN101688227B (zh) | 2007-01-26 | 2013-07-24 | 科森生物科学公司 | 通过工程化生物合成制备的大环内酰胺 |
| US20090258869A1 (en) * | 2008-02-08 | 2009-10-15 | The Regents Of The University Of California | Methods and compounds for treatment or prevention of substance-related disorders |
| MX2019000342A (es) * | 2016-07-08 | 2019-09-04 | Ranedis Pharmaceuticals Llc | Composiciones y metodos para tratar y/o prevenir enfermedades de almacenamiento lisosomal y otras enfermedades metabolicas monogeneticas. |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4261989A (en) | 1979-02-19 | 1981-04-14 | Kaken Chemical Co. Ltd. | Geldanamycin derivatives and antitumor drug |
| US5932566A (en) | 1994-06-16 | 1999-08-03 | Pfizer Inc. | Ansamycin derivatives as antioncogene and anticancer agents |
| US5662883A (en) | 1995-01-10 | 1997-09-02 | Nanosystems L.L.C. | Microprecipitation of micro-nanoparticulate pharmaceutical agents |
| US5534270A (en) | 1995-02-09 | 1996-07-09 | Nanosystems Llc | Method of preparing stable drug nanoparticles |
| US5510118A (en) | 1995-02-14 | 1996-04-23 | Nanosystems Llc | Process for preparing therapeutic compositions containing nanoparticles |
| US6682758B1 (en) | 1998-12-22 | 2004-01-27 | The United States Of America As Represented By The Department Of Health And Human Services | Water-insoluble drug delivery system |
| EP1373215B1 (en) | 2001-03-30 | 2006-07-26 | THE UNITED STATES OF AMERICA, represented by THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH | Geldanamycin derivatives useful for treating cancer |
| US20040138160A1 (en) | 2001-04-27 | 2004-07-15 | Kenichiro Naito | Preventive/therapeutic method for cancer |
| US6872715B2 (en) | 2001-08-06 | 2005-03-29 | Kosan Biosciences, Inc. | Benzoquinone ansamycins |
| EP1435939B1 (en) * | 2001-09-24 | 2008-02-27 | Conforma Therapeutic Corporation | Process for preparing 17-allyl amino geldanamycin (17-aag) and other ansamycins |
| JP2005528390A (ja) | 2002-04-10 | 2005-09-22 | コンフォーマ・セラピューティクス・コーポレイション | アンサマイシン製剤およびその製造ならびに使用方法 |
| US20060148776A1 (en) | 2003-03-13 | 2006-07-06 | Conforma Therapeutics Corporation | Drug formulations having long and medium chain triglycerides |
| US20050043233A1 (en) | 2003-04-29 | 2005-02-24 | Boehringer Ingelheim International Gmbh | Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis |
| US7691838B2 (en) | 2003-05-30 | 2010-04-06 | Kosan Biosciences Incorporated | Method for treating diseases using HSP90-inhibiting agents in combination with antimitotics |
| US20050054589A1 (en) | 2003-05-30 | 2005-03-10 | Kosan Biosciences, Inc. | Method for treating diseases using HSP90-inhibiting agents in combination with antibiotics |
| US20050020556A1 (en) | 2003-05-30 | 2005-01-27 | Kosan Biosciences, Inc. | Method for treating diseases using HSP90-inhibiting agents in combination with platinum coordination complexes |
| US20050020534A1 (en) | 2003-05-30 | 2005-01-27 | Kosan Biosciences, Inc. | Method for treating diseases using HSP90-inhibiting agents in combination with antimetabolites |
| US20050054625A1 (en) | 2003-05-30 | 2005-03-10 | Kosan Biosciences, Inc. | Method for treating diseases using HSP90-inhibiting agents in combination with nuclear export inhibitors |
| US20050020557A1 (en) | 2003-05-30 | 2005-01-27 | Kosan Biosciences, Inc. | Method for treating diseases using HSP90-inhibiting agents in combination with enzyme inhibitors |
| US20050026893A1 (en) | 2003-05-30 | 2005-02-03 | Kosan Biosciences, Inc. | Method for treating diseases using HSP90-inhibiting agents in combination with immunosuppressants |
| US6887993B1 (en) | 2003-11-12 | 2005-05-03 | Kosan Biosciences, Inc. | 11-O-methylgeldanamycin compounds |
| US20050256097A1 (en) | 2004-05-11 | 2005-11-17 | Kosan Biosciences, Inc. | Pharmaceutical solution formulations containing 17-AAG |
| US20080171687A1 (en) | 2004-09-16 | 2008-07-17 | Abraxis Bioscience, Inc. | Compositions And Methods For The Preparation And Administration Of Poorly Water Soluble Drugs |
| US20060067953A1 (en) | 2004-09-29 | 2006-03-30 | Conforma Therapeutics Corporation | Oral pharmaceutical formulations and methods for producing and using same |
| JP2008531708A (ja) | 2005-02-28 | 2008-08-14 | コーザン バイオサイエンシス インコーポレイテッド | １７−アリルアミノ−１７−デメトキシゲルダナマイシンを含有する医薬製剤 |
| BRPI0608661A2 (pt) * | 2005-04-07 | 2010-01-19 | Conforma Therapeutics Corp | formulaÇço farmacÊutica, uso de formulaÇço farmacÊutica, e, mÉtodo de preparaÇço de uma formulaÇço farmacÊutica |
-
2006
- 2006-11-08 US US11/595,005 patent/US7648976B2/en not_active Expired - Fee Related
- 2006-11-16 KR KR1020087015304A patent/KR20080089357A/ko not_active Withdrawn
- 2006-11-16 JP JP2008542377A patent/JP2009517386A/ja not_active Abandoned
- 2006-11-16 WO PCT/US2006/044746 patent/WO2007061878A2/en not_active Ceased
- 2006-11-16 AU AU2006318771A patent/AU2006318771A1/en not_active Abandoned
- 2006-11-16 EP EP06837958A patent/EP1951223A4/en not_active Withdrawn
- 2006-11-16 BR BRPI0618873A patent/BRPI0618873A2/pt not_active IP Right Cessation
- 2006-11-16 CA CA002629196A patent/CA2629196A1/en not_active Abandoned
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