JP2009514813A5 - - Google Patents
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- JP2009514813A5 JP2009514813A5 JP2008536725A JP2008536725A JP2009514813A5 JP 2009514813 A5 JP2009514813 A5 JP 2009514813A5 JP 2008536725 A JP2008536725 A JP 2008536725A JP 2008536725 A JP2008536725 A JP 2008536725A JP 2009514813 A5 JP2009514813 A5 JP 2009514813A5
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- JP
- Japan
- Prior art keywords
- composition
- ligand
- antibody
- plgf
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000203 mixture Substances 0.000 claims 25
- 239000003446 ligand Substances 0.000 claims 21
- 101000595923 Homo sapiens Placenta growth factor Proteins 0.000 claims 19
- 102100035194 Placenta growth factor Human genes 0.000 claims 19
- 108090000765 processed proteins & peptides Proteins 0.000 claims 13
- 206010028980 Neoplasm Diseases 0.000 claims 11
- 239000000427 antigen Substances 0.000 claims 10
- 108091007433 antigens Proteins 0.000 claims 10
- 102000036639 antigens Human genes 0.000 claims 10
- 238000000034 method Methods 0.000 claims 7
- -1 antibody analog Proteins 0.000 claims 6
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- 101100381481 Caenorhabditis elegans baz-2 gene Proteins 0.000 claims 4
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- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 4
- 101100372762 Rattus norvegicus Flt1 gene Proteins 0.000 claims 4
- 108020001507 fusion proteins Proteins 0.000 claims 4
- 102000037865 fusion proteins Human genes 0.000 claims 4
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 3
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- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims 3
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- 102100032768 Complement receptor type 2 Human genes 0.000 claims 1
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- 102000004190 Enzymes Human genes 0.000 claims 1
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- 108010066687 Epithelial Cell Adhesion Molecule Proteins 0.000 claims 1
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- 102100037362 Fibronectin Human genes 0.000 claims 1
- 108010067306 Fibronectins Proteins 0.000 claims 1
- 208000010412 Glaucoma Diseases 0.000 claims 1
- 102100041003 Glutamate carboxypeptidase 2 Human genes 0.000 claims 1
- 102100030595 HLA class II histocompatibility antigen gamma chain Human genes 0.000 claims 1
- 102000006354 HLA-DR Antigens Human genes 0.000 claims 1
- 108010058597 HLA-DR Antigens Proteins 0.000 claims 1
- 102100032742 Histone-lysine N-methyltransferase SETD2 Human genes 0.000 claims 1
- 208000017604 Hodgkin disease Diseases 0.000 claims 1
- 208000021519 Hodgkin lymphoma Diseases 0.000 claims 1
- 208000010747 Hodgkins lymphoma Diseases 0.000 claims 1
- 101001022185 Homo sapiens Alpha-(1,3)-fucosyltransferase 4 Proteins 0.000 claims 1
- 101000884305 Homo sapiens B-cell receptor CD22 Proteins 0.000 claims 1
- 101000980825 Homo sapiens B-lymphocyte antigen CD19 Proteins 0.000 claims 1
- 101000897405 Homo sapiens B-lymphocyte antigen CD20 Proteins 0.000 claims 1
- 101000914326 Homo sapiens Carcinoembryonic antigen-related cell adhesion molecule 6 Proteins 0.000 claims 1
- 101000721661 Homo sapiens Cellular tumor antigen p53 Proteins 0.000 claims 1
- 101000941929 Homo sapiens Complement receptor type 2 Proteins 0.000 claims 1
- 101000892862 Homo sapiens Glutamate carboxypeptidase 2 Proteins 0.000 claims 1
- 101001082627 Homo sapiens HLA class II histocompatibility antigen gamma chain Proteins 0.000 claims 1
- 101000654725 Homo sapiens Histone-lysine N-methyltransferase SETD2 Proteins 0.000 claims 1
- 101001057504 Homo sapiens Interferon-stimulated gene 20 kDa protein Proteins 0.000 claims 1
- 101001055144 Homo sapiens Interleukin-2 receptor subunit alpha Proteins 0.000 claims 1
- 101000878605 Homo sapiens Low affinity immunoglobulin epsilon Fc receptor Proteins 0.000 claims 1
- 101001133056 Homo sapiens Mucin-1 Proteins 0.000 claims 1
- 101001133081 Homo sapiens Mucin-2 Proteins 0.000 claims 1
- 101000972284 Homo sapiens Mucin-3A Proteins 0.000 claims 1
- 101000972286 Homo sapiens Mucin-4 Proteins 0.000 claims 1
- 101001012157 Homo sapiens Receptor tyrosine-protein kinase erbB-2 Proteins 0.000 claims 1
- 101000738771 Homo sapiens Receptor-type tyrosine-protein phosphatase C Proteins 0.000 claims 1
- 101000934341 Homo sapiens T-cell surface glycoprotein CD5 Proteins 0.000 claims 1
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- 208000015914 Non-Hodgkin lymphomas Diseases 0.000 claims 1
- KUIFHYPNNRVEKZ-VIJRYAKMSA-N O-(N-acetyl-alpha-D-galactosaminyl)-L-threonine Chemical compound OC(=O)[C@@H](N)[C@@H](C)O[C@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1NC(C)=O KUIFHYPNNRVEKZ-VIJRYAKMSA-N 0.000 claims 1
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- QCQYVCMYGCHVMR-AAZUGDAUSA-N n-[(2r,3r,4s,5r)-4,5,6-trihydroxy-1-oxo-3-[(2r,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexan-2-yl]acetamide Chemical compound CC(=O)N[C@@H](C=O)[C@H]([C@@H](O)[C@H](O)CO)O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O QCQYVCMYGCHVMR-AAZUGDAUSA-N 0.000 claims 1
- YOHYSYJDKVYCJI-UHFFFAOYSA-N n-[3-[[6-[3-(trifluoromethyl)anilino]pyrimidin-4-yl]amino]phenyl]cyclopropanecarboxamide Chemical compound FC(F)(F)C1=CC=CC(NC=2N=CN=C(NC=3C=C(NC(=O)C4CC4)C=CC=3)C=2)=C1 YOHYSYJDKVYCJI-UHFFFAOYSA-N 0.000 claims 1
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72829205P | 2005-10-19 | 2005-10-19 | |
| US60/728,292 | 2005-10-19 | ||
| PCT/US2006/040431 WO2007047609A2 (en) | 2005-10-19 | 2006-10-16 | INHIBITION OF PLACENTA GROWTH FACTOR (PlGF) MEDICATED METASTASIS AND/OR ANGIOGENESIS |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009514813A JP2009514813A (ja) | 2009-04-09 |
| JP2009514813A5 true JP2009514813A5 (enExample) | 2009-10-15 |
| JP5498018B2 JP5498018B2 (ja) | 2014-05-21 |
Family
ID=37963183
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008536725A Expired - Fee Related JP5498018B2 (ja) | 2005-10-19 | 2006-10-16 | 胎盤成長因子（ＰｌＧＦ）媒介性の転移および／または血管新生の阻害 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US7642239B2 (enExample) |
| EP (1) | EP1937724A4 (enExample) |
| JP (1) | JP5498018B2 (enExample) |
| KR (1) | KR101287280B1 (enExample) |
| CN (2) | CN101534865A (enExample) |
| AU (1) | AU2006304418B2 (enExample) |
| CA (1) | CA2625992C (enExample) |
| WO (1) | WO2007047609A2 (enExample) |
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7591994B2 (en) | 2002-12-13 | 2009-09-22 | Immunomedics, Inc. | Camptothecin-binding moiety conjugates |
| US7878978B2 (en) | 2004-03-18 | 2011-02-01 | University Of Pittsburgh- Of The Commonwealth System Of Higher Education | Use of relaxin to increase arterial compliance |
| US8067006B2 (en) | 2005-04-06 | 2011-11-29 | Immunomedics, Inc. | Polymeric carriers of therapeutic agents and recognition moieties for antibody-based targeting of disease sites |
| WO2008073828A2 (en) * | 2006-12-08 | 2008-06-19 | Northwestern University | Compositions and methods for magnetic resonance imaging contrast agents |
| US20080299077A1 (en) * | 2007-06-01 | 2008-12-04 | Nevada Cancer Institute | Isolation and growth of stem cells from hemangiomas |
| WO2008151021A1 (en) * | 2007-06-01 | 2008-12-11 | Nevada Cancer Institute | Isolation and growth of stem cells from hemangiomas |
| WO2009080764A2 (en) * | 2007-12-20 | 2009-07-02 | Abylnx N.V. | Oral or nasal administration of compounds comprising amino acid sequences |
| US8034396B2 (en) * | 2008-04-01 | 2011-10-11 | Tyco Healthcare Group Lp | Bioadhesive composition formed using click chemistry |
| EP2116555A1 (en) * | 2008-05-08 | 2009-11-11 | Bayer Schering Pharma Aktiengesellschaft | Use of a radioactively labelled molecule specifically binding to ED-B fibronectin in a method of treatment of Hodgkin lymphoma |
| BRPI0912560A2 (pt) * | 2008-05-16 | 2019-09-24 | Corthera Inc | método de promoção da cura de feridas |
| US20100004306A1 (en) * | 2008-06-18 | 2010-01-07 | Abbott Laboratories | PIGF-1 Assay and kits and components thereof |
| WO2009155381A1 (en) * | 2008-06-18 | 2009-12-23 | Abbott Laboratories | P/gf-1 companion diagnostic methods and products |
| US8741287B2 (en) * | 2008-06-18 | 2014-06-03 | Abbott Laboratories | PlGF-1 assay and kits and components thereof |
| AU2009299744B2 (en) * | 2008-10-02 | 2015-08-20 | Life Sciences Research Partners Vzw | Inhibition of PLGF to treat Philadelphia chromosome positive leukemia |
| US8940331B2 (en) * | 2008-11-22 | 2015-01-27 | The Board Of Trustees Of The Leland Stanford Junior University | Hydrogels, methods of making hydrogels, methods of using hydrogels, and methods of isolating, trapping, attracting, and/or killing cancer cells |
| KR20160021308A (ko) * | 2008-12-23 | 2016-02-24 | 제넨테크, 인크. | 암 환자에서의 진단 목적용 방법 및 조성물 |
| PL3939617T3 (pl) | 2009-02-13 | 2025-03-17 | Immunomedics, Inc. | Związki pośrednie do wytwarzania koniugatów z wiązaniem rozszczepialnym wewnątrzkomórkowo |
| US8535477B2 (en) * | 2009-02-21 | 2013-09-17 | Sofradim Production | Medical devices incorporating functional adhesives |
| US8512728B2 (en) | 2009-02-21 | 2013-08-20 | Sofradim Production | Method of forming a medical device on biological tissue |
| US8648144B2 (en) | 2009-02-21 | 2014-02-11 | Sofradim Production | Crosslinked fibers and method of making same by extrusion |
| EP2398850B1 (en) | 2009-02-21 | 2018-08-22 | Sofradim Production | Medical devices with an activated coating |
| AU2010215194A1 (en) | 2009-02-21 | 2011-10-13 | Sofradim Production | Apparatus and method of reacting polymers passing through metal ion chelated resin matrix to produce injectable medical devices |
| US8663689B2 (en) * | 2009-02-21 | 2014-03-04 | Sofradim Production | Functionalized adhesive medical gel |
| AU2010215931A1 (en) | 2009-02-21 | 2011-10-13 | Covidien Lp | Medical devices having activated surfaces |
| US8968733B2 (en) * | 2009-02-21 | 2015-03-03 | Sofradim Production | Functionalized surgical adhesives |
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-
2006
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- 2006-10-16 WO PCT/US2006/040431 patent/WO2007047609A2/en not_active Ceased
- 2006-10-16 US US11/581,287 patent/US7642239B2/en not_active Expired - Fee Related
- 2006-10-16 KR KR1020087009357A patent/KR101287280B1/ko not_active Expired - Fee Related
- 2006-10-16 CA CA2625992A patent/CA2625992C/en not_active Expired - Fee Related
- 2006-10-16 AU AU2006304418A patent/AU2006304418B2/en not_active Ceased
- 2006-10-16 JP JP2008536725A patent/JP5498018B2/ja not_active Expired - Fee Related
- 2006-10-16 CN CNA200680039268XA patent/CN101534849A/zh active Pending
- 2006-10-16 EP EP06826058A patent/EP1937724A4/en not_active Withdrawn
-
2009
- 2009-11-17 US US12/620,013 patent/US7932212B2/en not_active Expired - Fee Related
-
2011
- 2011-03-11 US US13/046,205 patent/US20110189268A1/en not_active Abandoned
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