JP2009512844A - アグリカンおよびそのフラグメントの検出または定量 - Google Patents

アグリカンおよびそのフラグメントの検出または定量 Download PDF

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JP2009512844A
JP2009512844A JP2008536049A JP2008536049A JP2009512844A JP 2009512844 A JP2009512844 A JP 2009512844A JP 2008536049 A JP2008536049 A JP 2008536049A JP 2008536049 A JP2008536049 A JP 2008536049A JP 2009512844 A JP2009512844 A JP 2009512844A
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aggrecan
binding partner
sample
immune
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JP2008536049A
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English (en)
Japanese (ja)
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JP2009512844A5 (https=
Inventor
シュメール，エレン・ウフク
クヴィスト，ペール
Original Assignee
ノルディック・バイオサイエンス・ダイアグノスティクス・アクティーゼルスカブ
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Priority claimed from GB0521392A external-priority patent/GB0521392D0/en
Priority claimed from GB0608947A external-priority patent/GB0608947D0/en
Application filed by ノルディック・バイオサイエンス・ダイアグノスティクス・アクティーゼルスカブ filed Critical ノルディック・バイオサイエンス・ダイアグノスティクス・アクティーゼルスカブ
Publication of JP2009512844A publication Critical patent/JP2009512844A/ja
Publication of JP2009512844A5 publication Critical patent/JP2009512844A5/ja
Withdrawn legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4722—Proteoglycans, e.g. aggreccan
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2008536049A 2005-10-20 2006-10-17 アグリカンおよびそのフラグメントの検出または定量 Withdrawn JP2009512844A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0521392A GB0521392D0 (en) 2005-10-20 2005-10-20 Detection or quantification of aggrecan and its fragments
GB0608947A GB0608947D0 (en) 2006-05-05 2006-05-05 Detection or quantification of aggrecan and its fragments
PCT/EP2006/067520 WO2007045661A1 (en) 2005-10-20 2006-10-17 Detection or quantification of aggrecan and its fragments

Publications (2)

Publication Number Publication Date
JP2009512844A true JP2009512844A (ja) 2009-03-26
JP2009512844A5 JP2009512844A5 (https=) 2009-12-03

Family

ID=37622298

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008536049A Withdrawn JP2009512844A (ja) 2005-10-20 2006-10-17 アグリカンおよびそのフラグメントの検出または定量

Country Status (4)

Country Link
US (1) US20090291462A1 (https=)
EP (1) EP1938106A1 (https=)
JP (1) JP2009512844A (https=)
WO (1) WO2007045661A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021526131A (ja) * 2018-05-30 2021-09-30 中外製薬株式会社 アグリカン結合ドメインおよび運搬部分を含むポリペプチド
US11932697B2 (en) 2016-11-28 2024-03-19 Chugai Seiyaku Kabushiki Kaisha Antigen-binding domain, and polypeptide including conveying section
US12030955B2 (en) 2017-11-28 2024-07-09 Chugai Seiyaku Kabushiki Kaisha Polypeptide including antigen-binding domain and carrying section

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102246045B (zh) 2008-10-16 2014-04-02 希托尼克斯公司 用于检测和治疗脊柱和关节疼痛的生物标志物和方法
US20110189694A1 (en) * 2008-10-22 2011-08-04 Biomarker Design Forschungs Gmbh Methods for detection and diagnosis of a bone or cartilage disorder
AU2012367247B2 (en) * 2012-01-24 2018-04-05 Cd Diagnostics, Inc. System for detecting infection in synovial fluid
EP3630818A1 (en) * 2017-06-02 2020-04-08 Ablynx NV Aggrecan binding immunoglobulins
CN114217078A (zh) * 2021-12-23 2022-03-22 西安依朵生物科技有限公司 一种检测聚集蛋白聚糖的试纸条、试剂盒及检测方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8304836D0 (sv) * 1983-09-09 1983-09-09 Pharmacia Ab Sett att bestemma forendringar i ledbrosk
US4704356A (en) * 1984-03-27 1987-11-03 Rush-Presbyterian-St. Luke's Medical Center Method of diagnosing cartilage tissue abnormalities
US5185245A (en) * 1989-02-24 1993-02-09 Thomas Jefferson University Immumoassays and kit for detection of proteoglycans
US5217903A (en) * 1990-05-15 1993-06-08 Trustees Of Boston University Measuring connective tissue breakdown products in body fluids
US5427954A (en) * 1992-04-29 1995-06-27 Shriner's Hospitals For Crippled Children Compositions and methods for detection and treatment of human osteoarthritis
US5387504A (en) * 1992-09-30 1995-02-07 Merck & Co., Inc. Monospecific antibodies and assay system for detecting stromelysin cleavage products
WO1995022765A1 (en) * 1994-02-19 1995-08-24 Seikagaku Kogyo Kabushiki Kaisha Method of assaying normal aglycan, assaying kit, and method of judging joint-related information
US5935796A (en) * 1995-06-30 1999-08-10 The University Of Melbourne Diagnostic methods and compositions relating to the proteoglycan proteins of cartilage breakdown
RU2164914C2 (ru) * 1995-11-13 2001-04-10 Хехст Акциенгезелльшафт ЦИКЛИЧЕСКИЕ И ГЕТЕРОЦИКЛИЧЕСКИЕ N-ЗАМЕЩЕННЫЕ α-ИМИНОГИДРОКСАМОВЫЕ И КАРБОНОВЫЕ КИСЛОТЫ

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11932697B2 (en) 2016-11-28 2024-03-19 Chugai Seiyaku Kabushiki Kaisha Antigen-binding domain, and polypeptide including conveying section
US12030955B2 (en) 2017-11-28 2024-07-09 Chugai Seiyaku Kabushiki Kaisha Polypeptide including antigen-binding domain and carrying section
JP2021526131A (ja) * 2018-05-30 2021-09-30 中外製薬株式会社 アグリカン結合ドメインおよび運搬部分を含むポリペプチド
JP7414736B2 (ja) 2018-05-30 2024-01-16 中外製薬株式会社 アグリカン結合ドメインおよび運搬部分を含むポリペプチド
US12077577B2 (en) 2018-05-30 2024-09-03 Chugai Seiyaku Kabushiki Kaisha Polypeptide comprising aggrecan binding domain and carrying moiety

Also Published As

Publication number Publication date
EP1938106A1 (en) 2008-07-02
WO2007045661A1 (en) 2007-04-26
US20090291462A1 (en) 2009-11-26

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