JP2009511597A5 - - Google Patents
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- Publication number
- JP2009511597A5 JP2009511597A5 JP2008535706A JP2008535706A JP2009511597A5 JP 2009511597 A5 JP2009511597 A5 JP 2009511597A5 JP 2008535706 A JP2008535706 A JP 2008535706A JP 2008535706 A JP2008535706 A JP 2008535706A JP 2009511597 A5 JP2009511597 A5 JP 2009511597A5
- Authority
- JP
- Japan
- Prior art keywords
- acute
- renal failure
- use according
- acute renal
- medicament
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 208000009304 Acute Kidney Injury Diseases 0.000 claims 4
- 208000033626 Renal failure acute Diseases 0.000 claims 4
- 201000011040 acute kidney failure Diseases 0.000 claims 4
- 208000012998 acute renal failure Diseases 0.000 claims 4
- 102000012607 Thrombomodulin Human genes 0.000 claims 2
- 108010079274 Thrombomodulin Proteins 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 208000003918 Acute Kidney Tubular Necrosis Diseases 0.000 claims 1
- 206010063897 Renal ischaemia Diseases 0.000 claims 1
- 206010038540 Renal tubular necrosis Diseases 0.000 claims 1
- 206010048302 Tubulointerstitial nephritis Diseases 0.000 claims 1
- 230000002757 inflammatory effect Effects 0.000 claims 1
- 230000000302 ischemic effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72637605P | 2005-10-13 | 2005-10-13 | |
| US60/726,376 | 2005-10-13 | ||
| PCT/US2006/040069 WO2007047430A2 (en) | 2005-10-13 | 2006-10-12 | Method of treating acute failure with thrombomodulin variant |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009511597A JP2009511597A (ja) | 2009-03-19 |
| JP2009511597A5 true JP2009511597A5 (enExample) | 2009-11-12 |
| JP5405829B2 JP5405829B2 (ja) | 2014-02-05 |
Family
ID=37670944
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008535706A Expired - Fee Related JP5405829B2 (ja) | 2005-10-13 | 2006-10-12 | トロンボモジュリン変異体を用いた急性障害の治療方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20080255047A1 (enExample) |
| EP (1) | EP1948216B1 (enExample) |
| JP (1) | JP5405829B2 (enExample) |
| AT (1) | ATE503489T1 (enExample) |
| CA (1) | CA2625888C (enExample) |
| CY (1) | CY1112438T1 (enExample) |
| DE (1) | DE602006021048D1 (enExample) |
| DK (1) | DK1948216T3 (enExample) |
| ES (1) | ES2360610T3 (enExample) |
| PL (1) | PL1948216T3 (enExample) |
| PT (1) | PT1948216E (enExample) |
| SI (1) | SI1948216T1 (enExample) |
| WO (1) | WO2007047430A2 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8076298B2 (en) | 2006-12-12 | 2011-12-13 | Eli Lilly And Company | Treating acute renal failure with soluble thrombomodulin variants |
| BRPI0922033A2 (pt) * | 2008-11-12 | 2015-12-15 | Lilly Co Eli | composições e métodos de uso de variantes de trombomodulina |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2022713A1 (en) * | 1989-08-11 | 1991-02-12 | Nils U. Bang | Human thrombomodulin derivatives |
| CA2129370A1 (en) * | 1992-02-05 | 1993-08-19 | David Richard Light | Protease-resistant thrombomodulin analogs |
| ATE249234T1 (de) * | 1993-12-17 | 2003-09-15 | Mochida Pharm Co Ltd | Lösliches thrombomodulin enthaltende zubereitung |
| US20050106124A1 (en) * | 2003-02-25 | 2005-05-19 | Sehgal Lakshman R. | Therapeutic applications of thrombomodulin gene via viral and non-viral vectors |
-
2006
- 2006-10-12 US US12/088,564 patent/US20080255047A1/en not_active Abandoned
- 2006-10-12 JP JP2008535706A patent/JP5405829B2/ja not_active Expired - Fee Related
- 2006-10-12 CA CA2625888A patent/CA2625888C/en not_active Expired - Fee Related
- 2006-10-12 WO PCT/US2006/040069 patent/WO2007047430A2/en not_active Ceased
- 2006-10-12 EP EP06825898A patent/EP1948216B1/en not_active Not-in-force
- 2006-10-12 DK DK06825898.7T patent/DK1948216T3/da active
- 2006-10-12 DE DE602006021048T patent/DE602006021048D1/de active Active
- 2006-10-12 ES ES06825898T patent/ES2360610T3/es active Active
- 2006-10-12 PT PT06825898T patent/PT1948216E/pt unknown
- 2006-10-12 PL PL06825898T patent/PL1948216T3/pl unknown
- 2006-10-12 SI SI200631016T patent/SI1948216T1/sl unknown
- 2006-10-12 AT AT06825898T patent/ATE503489T1/de active
-
2011
- 2011-05-13 CY CY20111100452T patent/CY1112438T1/el unknown