JP2009510093A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009510093A5 JP2009510093A5 JP2008533624A JP2008533624A JP2009510093A5 JP 2009510093 A5 JP2009510093 A5 JP 2009510093A5 JP 2008533624 A JP2008533624 A JP 2008533624A JP 2008533624 A JP2008533624 A JP 2008533624A JP 2009510093 A5 JP2009510093 A5 JP 2009510093A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- seq
- disease
- isolated
- soluble polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72116205P | 2005-09-28 | 2005-09-28 | |
| US75379405P | 2005-12-22 | 2005-12-22 | |
| US77202206P | 2006-02-10 | 2006-02-10 | |
| US78224706P | 2006-03-14 | 2006-03-14 | |
| PCT/US2006/037950 WO2007038703A2 (en) | 2005-09-28 | 2006-09-28 | Il-17a and il-17f antagonists and methods of using the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009510093A JP2009510093A (ja) | 2009-03-12 |
| JP2009510093A5 true JP2009510093A5 (https=) | 2009-11-12 |
Family
ID=37672342
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008533624A Pending JP2009510093A (ja) | 2005-09-28 | 2006-09-28 | Ｉｌ−１７ａおよびｉｌ−１７ｆアンタゴニストならびにその使用方法 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20070238658A1 (https=) |
| EP (1) | EP1931697B1 (https=) |
| JP (1) | JP2009510093A (https=) |
| KR (1) | KR20080056241A (https=) |
| AT (1) | ATE481424T1 (https=) |
| AU (1) | AU2006294511B2 (https=) |
| BR (1) | BRPI0616589A2 (https=) |
| CA (1) | CA2621623A1 (https=) |
| CY (1) | CY1110856T1 (https=) |
| DE (1) | DE602006016965D1 (https=) |
| DK (1) | DK1931697T3 (https=) |
| EA (1) | EA015351B1 (https=) |
| IL (1) | IL189726A0 (https=) |
| PL (1) | PL1931697T3 (https=) |
| PT (1) | PT1931697E (https=) |
| WO (1) | WO2007038703A2 (https=) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2784084B2 (en) | 2003-07-08 | 2023-10-04 | Novartis Pharma AG | Antagonist antibodies to IL-17A/F heterologous polypeptides |
| US7910540B2 (en) * | 2004-06-10 | 2011-03-22 | Zymogenetics, Inc. | Soluble ZcytoR14, anti-ZcytoR14 antibodies and binding partners and methods of using in inflammation |
| JP2008507288A (ja) | 2004-07-23 | 2008-03-13 | アクセルロン ファーマ インコーポレーテッド | ＡｃｔＲＩＩ受容体ポリペプチド、方法、および組成物 |
| US7723477B2 (en) | 2005-10-31 | 2010-05-25 | Oncomed Pharmaceuticals, Inc. | Compositions and methods for inhibiting Wnt-dependent solid tumor cell growth |
| CA2628221A1 (en) | 2005-10-31 | 2007-05-10 | Oncomed Pharmaceuticals, Inc. | Anti-frizzled receptor antibodies for treating cancer |
| ES2649983T3 (es) | 2005-11-23 | 2018-01-16 | Acceleron Pharma, Inc. | Antagonistas de activina-ActRIIa en su uso para promover el crecimiento óseo |
| US8128933B2 (en) | 2005-11-23 | 2012-03-06 | Acceleron Pharma, Inc. | Method of promoting bone growth by an anti-activin B antibody |
| AU2006328899A1 (en) * | 2005-12-22 | 2007-06-28 | Merck Serono Sa | Soluble IL-17RC variant and uses thereof |
| WO2008039553A1 (en) * | 2006-02-10 | 2008-04-03 | Zymogenetics, Inc. | Soluble il-17rcx4 and methods of using in inflammation |
| US8895016B2 (en) | 2006-12-18 | 2014-11-25 | Acceleron Pharma, Inc. | Antagonists of activin-actriia and uses for increasing red blood cell levels |
| MX2009008222A (es) | 2007-02-01 | 2009-10-12 | Acceleron Pharma Inc | Antagonistas de activina-actriia y usos para tratar o prevenir cancer de mama. |
| TW201803890A (zh) | 2007-02-02 | 2018-02-01 | 艾瑟勒朗法瑪公司 | 衍生自ＡｃｔＲＩＩＢ的變體與其用途 |
| EA018221B1 (ru) | 2007-02-09 | 2013-06-28 | Акселерон Фарма Инк. | АНТАГОНИСТЫ АКТИВИНА-ActRIIa И ПРИМЕНЕНИЕ ДЛЯ СТИМУЛЯЦИИ РОСТА КОСТИ У БОЛЬНЫХ РАКОМ |
| US7790676B2 (en) | 2007-03-28 | 2010-09-07 | Zymogenetics, Inc. | Soluble IL-17RA/RC fusion proteins |
| EP2144930A1 (en) | 2007-04-18 | 2010-01-20 | ZymoGenetics, Inc. | Single chain fc, methods of making and methods of treatment |
| EP2144928A2 (en) * | 2007-04-20 | 2010-01-20 | Amgen Inc. | Jacquelinidentification and method for using the pre-ligand assembly domain of the il-17 receptor |
| US20100239590A1 (en) * | 2007-06-20 | 2010-09-23 | Schering Corporation | Joint destruction biomarkers for anti-il-17a therapy of inflammatory joint disease |
| CN101861161B (zh) | 2007-09-18 | 2017-04-19 | 阿塞勒隆制药公司 | 活化素‑actriia拮抗剂和减少或抑制fsh分泌的用途 |
| TW201803586A (zh) | 2008-08-14 | 2018-02-01 | 艾瑟勒朗法瑪公司 | 使用ｇｄｆ阱以增加紅血球水平 |
| US8216997B2 (en) | 2008-08-14 | 2012-07-10 | Acceleron Pharma, Inc. | Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators |
| SG190568A1 (en) | 2008-09-26 | 2013-06-28 | Oncomed Pharm Inc | Frizzled-binding agents and uses thereof |
| AU2010204985A1 (en) | 2009-01-13 | 2011-08-04 | Acceleron Pharma Inc. | Methods for increasing adiponectin |
| JP5755635B2 (ja) | 2009-03-30 | 2015-07-29 | アクセルロン ファーマ， インコーポレイテッド | Ｂｍｐ−ａｌｋ３アンタゴニストおよび骨成長促進のためのその使用 |
| KR20120049214A (ko) | 2009-06-08 | 2012-05-16 | 악셀레론 파마 인코포레이티드 | 발열성 지방세포를 증가시키는 방법 |
| KR20180026795A (ko) | 2009-06-12 | 2018-03-13 | 악셀레론 파마 인코포레이티드 | 절두된 ＡｃｔＲＩＩＢ-ＦＣ 융합 단백질 |
| MX2012002428A (es) | 2009-08-27 | 2012-09-12 | Covagen Ag | Compuestos de union il-17 y usos medicos de los mismos. |
| CA2774326C (en) | 2009-09-14 | 2023-11-07 | Donald Bellgrau | Modulation of yeast-based immunotherapy products and responses |
| EP3332796A1 (en) | 2009-11-17 | 2018-06-13 | Acceleron Pharma Inc. | Actriib proteins and variants and uses therefore relating to utrophin induction for muscular dystrophy therapy |
| TWI535445B (zh) | 2010-01-12 | 2016-06-01 | 安可美德藥物股份有限公司 | Ｗｎｔ拮抗劑及治療和篩選方法 |
| CA2794674A1 (en) | 2010-04-01 | 2011-10-06 | Oncomed Pharmaceuticals, Inc. | Frizzled-binding agents and uses thereof |
| AU2011326586A1 (en) | 2010-11-08 | 2013-05-30 | Acceleron Pharma, Inc. | ActRIIA binding agents and uses thereof |
| EP2809660B1 (en) | 2012-02-02 | 2016-01-20 | Ensemble Therapeutics Corporation | Macrocyclic compounds for modulating il-17 |
| AU2013334790A1 (en) | 2012-10-23 | 2015-04-30 | Oncomed Pharmaceuticals, Inc. | Methods of treating neuroendocrine tumors using Wnt pathway-binding agents |
| US10195249B2 (en) | 2012-11-02 | 2019-02-05 | Celgene Corporation | Activin-ActRII antagonists and uses for treating bone and other disorders |
| AU2014212081A1 (en) | 2013-02-04 | 2015-08-13 | Oncomed Pharmaceuticals, Inc. | Methods and monitoring of treatment with a Wnt pathway inhibitor |
| US9168300B2 (en) | 2013-03-14 | 2015-10-27 | Oncomed Pharmaceuticals, Inc. | MET-binding agents and uses thereof |
| CN103992400B (zh) * | 2014-05-29 | 2017-01-04 | 江苏吴中医药集团有限公司苏州中凯生物制药厂 | 重组人血管内皮抑素的复性液及其制备、使用方法 |
| CN114699529A (zh) | 2014-06-13 | 2022-07-05 | 阿塞勒隆制药公司 | 用于治疗溃疡的方法和组合物 |
| MA41052A (fr) | 2014-10-09 | 2017-08-15 | Celgene Corp | Traitement d'une maladie cardiovasculaire à l'aide de pièges de ligands d'actrii |
| JP2018501307A (ja) | 2014-12-03 | 2018-01-18 | セルジーン コーポレイション | アクチビン−ＡｃｔＲＩＩアンタゴニスト及び貧血を治療するための使用 |
| CN112543642A (zh) * | 2018-08-29 | 2021-03-23 | 戊瑞治疗有限公司 | CD80胞外结构域Fc融合蛋白给药方案 |
| CN113789346A (zh) * | 2021-08-25 | 2021-12-14 | 北京伟德杰生物科技有限公司 | 长效化重组人白细胞介素2融合蛋白及其制备方法和应用 |
| WO2025226984A1 (en) * | 2024-04-24 | 2025-10-30 | Mopac Biologics, Inc. | Human il-17 binding polypeptides |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4486533A (en) | 1982-09-02 | 1984-12-04 | St. Louis University | Filamentous fungi functional replicating extrachromosomal element |
| DE3572982D1 (en) | 1984-03-06 | 1989-10-19 | Takeda Chemical Industries Ltd | Chemically modified lymphokine and production thereof |
| US4882279A (en) | 1985-10-25 | 1989-11-21 | Phillips Petroleum Company | Site selective genomic modification of yeast of the genus pichia |
| US4935349A (en) | 1986-01-17 | 1990-06-19 | Zymogenetics, Inc. | Expression of higher eucaryotic genes in aspergillus |
| US5162228A (en) | 1988-12-28 | 1992-11-10 | Takeda Chemical Industries, Ltd. | Gylceraldehyde-3-phosphate dehydrogenase gene and promoter |
| US5252714A (en) | 1990-11-28 | 1993-10-12 | The University Of Alabama In Huntsville | Preparation and use of polyethylene glycol propionaldehyde |
| US5382657A (en) | 1992-08-26 | 1995-01-17 | Hoffmann-La Roche Inc. | Peg-interferon conjugates |
| US5738846A (en) | 1994-11-10 | 1998-04-14 | Enzon, Inc. | Interferon polymer conjugates and process for preparing the same |
| US5965389A (en) | 1995-11-09 | 1999-10-12 | Zymogenetics, Inc. | Production of GAD65 in methylotrophic yeast |
| US5716808A (en) | 1995-11-09 | 1998-02-10 | Zymogenetics, Inc. | Genetic engineering of pichia methanolica |
| JP2002514049A (ja) | 1996-07-17 | 2002-05-14 | ザイモジェネティクス，インコーポレイティド | ピヒア・メタノリカの栄養要求性突然変異体の製造 |
| US5736383A (en) | 1996-08-26 | 1998-04-07 | Zymogenetics, Inc. | Preparation of Pichia methanolica auxotrophic mutants |
| JP2002515746A (ja) | 1996-07-17 | 2002-05-28 | ザイモジェネティクス，インコーポレイティド | ピヒア・メタノリカの形質転換 |
| US6569645B2 (en) * | 1999-05-14 | 2003-05-27 | Genentech, Inc. | IL-17 homologous polypeptides and therapeutic uses thereof |
| US6579520B2 (en) * | 1998-05-15 | 2003-06-17 | Genentech, Inc. | IL-17 related mammalian cytokine polypeptides (IL-17E) |
| AU740405B2 (en) * | 1998-05-15 | 2001-11-01 | Genentech Inc. | IL-17 homologous polypeptides and therapeutic uses thereof |
| US20050147609A1 (en) * | 1998-05-15 | 2005-07-07 | Genentech, Inc. | Use of anti-IL-17 antibody for the treatment of cartilage damaged by osteoarthritis |
| EP2241623A3 (en) | 1999-07-07 | 2010-12-01 | ZymoGenetics, Inc. | Monoclonal antibody against a human cytokine receptor |
| US20030199041A1 (en) * | 1999-07-07 | 2003-10-23 | Presnell Scott R. | Interleukin-17 receptor homologue |
| US20030092881A1 (en) * | 2000-05-24 | 2003-05-15 | Gorman Daniel M. | Mammalian receptor proteins; related reagents and methods |
| US20040197306A1 (en) * | 2000-05-24 | 2004-10-07 | Gorman Daniel M. | Mammalian receptor proteins; related reagents and methods |
| CA2425506A1 (en) * | 2000-10-18 | 2002-08-01 | Immunex Corporation | Methods for treating rheumatoid arthritis using il-17 antagonists |
| US20040097447A1 (en) * | 2002-11-16 | 2004-05-20 | Isis Pharmaceuticals Inc. | Modulation of interleukin 22 receptor expression |
| JP2006508056A (ja) * | 2002-08-28 | 2006-03-09 | イミュネックス・コーポレーション | 心臓血管疾患を治療するための組成物および方法 |
| EP2784084B2 (en) * | 2003-07-08 | 2023-10-04 | Novartis Pharma AG | Antagonist antibodies to IL-17A/F heterologous polypeptides |
| US7910540B2 (en) | 2004-06-10 | 2011-03-22 | Zymogenetics, Inc. | Soluble ZcytoR14, anti-ZcytoR14 antibodies and binding partners and methods of using in inflammation |
-
2006
- 2006-09-28 JP JP2008533624A patent/JP2009510093A/ja active Pending
- 2006-09-28 WO PCT/US2006/037950 patent/WO2007038703A2/en not_active Ceased
- 2006-09-28 PL PL06815733T patent/PL1931697T3/pl unknown
- 2006-09-28 PT PT06815733T patent/PT1931697E/pt unknown
- 2006-09-28 BR BRPI0616589-3A patent/BRPI0616589A2/pt not_active IP Right Cessation
- 2006-09-28 DK DK06815733.8T patent/DK1931697T3/da active
- 2006-09-28 KR KR1020087010048A patent/KR20080056241A/ko not_active Ceased
- 2006-09-28 AU AU2006294511A patent/AU2006294511B2/en not_active Ceased
- 2006-09-28 AT AT06815733T patent/ATE481424T1/de active
- 2006-09-28 US US11/536,461 patent/US20070238658A1/en not_active Abandoned
- 2006-09-28 EA EA200800956A patent/EA015351B1/ru not_active IP Right Cessation
- 2006-09-28 CA CA002621623A patent/CA2621623A1/en not_active Abandoned
- 2006-09-28 DE DE602006016965T patent/DE602006016965D1/de active Active
- 2006-09-28 EP EP06815733A patent/EP1931697B1/en not_active Not-in-force
-
2008
- 2008-02-25 IL IL189726A patent/IL189726A0/en unknown
-
2010
- 2010-10-26 CY CY20101100962T patent/CY1110856T1/el unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2009510093A5 (https=) | ||
| JP2009526084A5 (https=) | ||
| JP2011526792A5 (https=) | ||
| JP2010273685A5 (https=) | ||
| JP2008509227A5 (https=) | ||
| JP2009527226A5 (https=) | ||
| JP2010511056A5 (https=) | ||
| JP2016510736A5 (https=) | ||
| JP2010220614A5 (https=) | ||
| US11279935B2 (en) | Method for screening prophylactic or therapeutic agents for diseases caused by interleukin 6, interleukin 13, TNF, G-CSF, CXCL1, CXCL2, or CXCL5 and agent for the prevention or treatment of diseases caused by interleukin 6, interleukin 13, TNF, G-CSF, CXCL1, CXCL2, or CXCL5 | |
| JP2007530435A5 (https=) | ||
| JP2012517818A5 (https=) | ||
| FI3842456T3 (fi) | Monoklonaalinen interleukiini-31-vasta-aine | |
| CN114957472B (zh) | 抗IL-4Rα的单域抗体以及应用和药物 | |
| JP2006516189A5 (https=) | ||
| ME02607B (me) | Molekuli antitela koji imaju specifično vezivanje za humani il-13 | |
| JP2010501167A5 (https=) | ||
| CA2465156A1 (en) | Il-21 antagonists | |
| JP2003527078A5 (https=) | ||
| JP2007075118A5 (https=) | ||
| JP2023080074A5 (https=) | ||
| WO2008049106A3 (en) | Process for preparing unaggregated antibody fc domains | |
| CN110003329B (zh) | 多肽、il17a/f单域抗体、核苷酸序列及试剂盒 | |
| CN102625836B (zh) | Hmgb1结合核酸分子及其用途 | |
| CN110003337B (zh) | Il17ra单域抗体、核酸及试剂盒 |