JP2009506759A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009506759A5 JP2009506759A5 JP2008528294A JP2008528294A JP2009506759A5 JP 2009506759 A5 JP2009506759 A5 JP 2009506759A5 JP 2008528294 A JP2008528294 A JP 2008528294A JP 2008528294 A JP2008528294 A JP 2008528294A JP 2009506759 A5 JP2009506759 A5 JP 2009506759A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- round
- reaction
- acid molecules
- amplification
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000006243 chemical reaction Methods 0.000 claims description 34
- 230000003321 amplification Effects 0.000 claims description 23
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 23
- 238000005382 thermal cycling Methods 0.000 claims description 9
- 150000007523 nucleic acids Chemical class 0.000 claims 36
- 238000000034 method Methods 0.000 claims 28
- 108020004707 nucleic acids Proteins 0.000 claims 28
- 102000039446 nucleic acids Human genes 0.000 claims 28
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 5
- 108091093088 Amplicon Proteins 0.000 claims 4
- 108020004414 DNA Proteins 0.000 claims 3
- 102000053602 DNA Human genes 0.000 claims 3
- 108090000790 Enzymes Proteins 0.000 claims 2
- 102000004190 Enzymes Human genes 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 238000001514 detection method Methods 0.000 claims 2
- 230000029087 digestion Effects 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 238000012544 monitoring process Methods 0.000 claims 2
- 239000000523 sample Substances 0.000 claims 2
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 1
- 206010071602 Genetic polymorphism Diseases 0.000 claims 1
- 108091034117 Oligonucleotide Proteins 0.000 claims 1
- 108020004682 Single-Stranded DNA Proteins 0.000 claims 1
- 238000011109 contamination Methods 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037765 diseases and disorders Diseases 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 238000012224 gene deletion Methods 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 238000011880 melting curve analysis Methods 0.000 claims 1
- 230000035772 mutation Effects 0.000 claims 1
- 230000037452 priming Effects 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71363605P | 2005-09-01 | 2005-09-01 | |
| AU2005205791A AU2005205791B1 (en) | 2005-09-01 | 2005-09-01 | Methods for the amplification and quantitation of nucleic acids |
| CA2545613A CA2545613C (en) | 2005-09-01 | 2006-04-05 | Methods for the amplification and quantitation of nucleic acids |
| PCT/AU2006/001265 WO2007025340A1 (en) | 2005-09-01 | 2006-08-31 | Methods for the amplification, quantitation and identification of nucleic acids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009506759A JP2009506759A (ja) | 2009-02-19 |
| JP2009506759A5 true JP2009506759A5 (cg-RX-API-DMAC10.html) | 2009-10-15 |
Family
ID=39807232
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008528294A Pending JP2009506759A (ja) | 2005-09-01 | 2006-08-31 | 核酸の増幅、定量化、及び同定の方法。 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8962250B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP1937834B1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP2009506759A (cg-RX-API-DMAC10.html) |
| KR (1) | KR101515821B1 (cg-RX-API-DMAC10.html) |
| ES (1) | ES2494922T3 (cg-RX-API-DMAC10.html) |
| PL (1) | PL1937834T3 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2007025340A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2674907C (en) * | 2007-01-31 | 2017-04-04 | Celera Corporation | A molecular prognostic signature for predicting breast cancer distant metastasis, and uses thereof |
| AU2008301233A1 (en) * | 2007-09-20 | 2009-03-26 | Molecular Plant Breeding Nominees Ltd | Method of amplifying nucleic acid |
| US20100285468A1 (en) * | 2007-09-24 | 2010-11-11 | Allelogic Biosciences Corporation | Detection and/or quantification of nucleic acids |
| DK2271767T3 (en) * | 2008-04-03 | 2016-08-29 | Cb Biotechnologies Inc | Amplikonredning-multiplex polymerase chain reaction for the amplification of multiple target |
| CA2749950C (en) * | 2009-01-30 | 2018-01-09 | Metcraft, Inc. | Silverware, flatware or parts washer apparatus and method thereof |
| CA2766391C (en) | 2009-07-01 | 2021-04-20 | Gen-Probe Incorporated | Methods and compositions for multiplex nucleic acid amplification |
| US9416419B2 (en) | 2009-11-16 | 2016-08-16 | Michael E. Hogan | Methods for PCR and HLA typing using unpurified samples |
| US8771951B2 (en) * | 2009-11-16 | 2014-07-08 | Genomics Usa, Inc. | Methods for PCR and HLA typing using raw blood |
| US8361720B2 (en) | 2010-11-15 | 2013-01-29 | Exact Sciences Corporation | Real time cleavage assay |
| US8916344B2 (en) | 2010-11-15 | 2014-12-23 | Exact Sciences Corporation | Methylation assay |
| EP3246416B1 (en) | 2011-04-15 | 2024-06-05 | The Johns Hopkins University | Safe sequencing system |
| EP2744916A4 (en) | 2011-07-13 | 2015-06-17 | Primeradx Inc | MULTIMODAL PROCEDURE FOR THE SIMULTANEOUS DETECTION AND QUANTIFICATION OF MULTIPLE NUCLEIC ACIDS IN ONE SAMPLE |
| HU229967B1 (hu) | 2011-12-20 | 2015-03-30 | Kps Diagnosztika Zrt | Eljárás töredezett nukleinsavak szekvenciájának meghatározására |
| EP4361606A3 (en) | 2012-02-03 | 2024-07-10 | California Institute of Technology | Signal encoding and decoding in multiplexed biochemical assays |
| CN108753932B (zh) | 2012-08-03 | 2022-12-02 | 加州理工学院 | Pcr中具有减少的硬件和要求的多重化和定量 |
| WO2014070462A1 (en) | 2012-10-29 | 2014-05-08 | The Johns Hopkins University | Papanicolaou test for ovarian and endometrial cancers |
| EP3303637B1 (en) * | 2015-06-02 | 2021-04-07 | BioFire Defense, LLC | Sample to sequence |
| US11286531B2 (en) | 2015-08-11 | 2022-03-29 | The Johns Hopkins University | Assaying ovarian cyst fluid |
| DK3356558T3 (da) | 2015-09-30 | 2022-04-25 | Immunexpress Pty Ltd | Sirs patogenbiomarkører og anvendelser deraf |
| CA3002196C (en) | 2015-10-30 | 2024-05-14 | Exact Sciences Development Company, Llc | Multiplex amplification detection assay and isolation and detection of dna from plasma |
| US20200371099A1 (en) | 2015-12-24 | 2020-11-26 | Immunexpress Pty Ltd | Triage biomarkers and uses therefor |
| KR101919190B1 (ko) * | 2016-04-27 | 2018-11-15 | 하이트진로 주식회사 | 미생물의 ２ 단계 분석 방법 |
| AU2017260630B2 (en) | 2016-05-05 | 2023-07-13 | Exact Sciences Corporation | Detection of lung neoplasia by analysis of methylated DNA |
| WO2017218777A1 (en) | 2016-06-17 | 2017-12-21 | California Institute Of Technology | Nucleic acid reactions and related methods and compositions |
| KR101785687B1 (ko) * | 2016-07-20 | 2017-10-17 | (주)다이오진 | 다중 증폭 이중 시그널 증폭에 의한 타겟 핵산 서열의 검출 방법 |
| AU2018211956B2 (en) | 2017-01-27 | 2024-06-20 | Exact Sciences Corporation | Detection of colon neoplasia by analysis of methylated DNA |
| AU2018273791A1 (en) | 2017-05-22 | 2019-12-12 | Edith Cowan University | Biomarker of disease |
| KR20250047324A (ko) | 2017-08-07 | 2025-04-03 | 더 존스 홉킨스 유니버시티 | 암을 평가하고 치료하기 위한 방법 및 재료 |
| US10648025B2 (en) | 2017-12-13 | 2020-05-12 | Exact Sciences Development Company, Llc | Multiplex amplification detection assay II |
| EP3731959B1 (en) | 2017-12-29 | 2025-10-08 | Clear Labs, Inc. | Automated priming and library loading device |
| EP3781710A4 (en) | 2018-04-17 | 2022-01-05 | Chromacode, Inc. | METHODS AND SYSTEMS FOR MULTIPLEX ANALYSIS |
| US12203129B2 (en) | 2018-07-03 | 2025-01-21 | ChromaCode, Inc. | Formulations and signal encoding and decoding methods for massively multiplexed biochemical assays |
| WO2021163546A1 (en) | 2020-02-14 | 2021-08-19 | The Johns Hopkins University | Methods and materials for assessing nucleic acids |
| US20240425925A1 (en) | 2021-10-29 | 2024-12-26 | GenoDx Pty Ltd | Biomarkers and uses therefor |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4965188A (en) * | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| US5210015A (en) * | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| KR100236506B1 (ko) | 1990-11-29 | 2000-01-15 | 퍼킨-엘머시터스인스트루먼츠 | 폴리머라제 연쇄 반응 수행 장치 |
| US5994056A (en) * | 1991-05-02 | 1999-11-30 | Roche Molecular Systems, Inc. | Homogeneous methods for nucleic acid amplification and detection |
| US5436134A (en) * | 1993-04-13 | 1995-07-25 | Molecular Probes, Inc. | Cyclic-substituted unsymmetrical cyanine dyes |
| US5658751A (en) * | 1993-04-13 | 1997-08-19 | Molecular Probes, Inc. | Substituted unsymmetrical cyanine dyes with selected permeability |
| US5538848A (en) * | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
| US5792611A (en) * | 1996-05-23 | 1998-08-11 | Natural Resources Canada, Canadian Forest Service | Detection of plant pathogenic fungi |
| DE69739357D1 (de) * | 1996-06-04 | 2009-05-28 | Univ Utah Res Found | Überwachung der hybridisierung während pcr |
| GB9725197D0 (en) * | 1997-11-29 | 1998-01-28 | Secr Defence | Detection system |
| US6432642B1 (en) * | 1999-01-15 | 2002-08-13 | Pe Corporation (Ny) | Binary probe and clamp composition and methods for a target hybridization detection |
| US6783934B1 (en) * | 2000-05-01 | 2004-08-31 | Cepheid, Inc. | Methods for quantitative analysis of nucleic acid amplification reaction |
| US6605451B1 (en) * | 2000-06-06 | 2003-08-12 | Xtrana, Inc. | Methods and devices for multiplexing amplification reactions |
| EP1474529B1 (en) * | 2002-02-08 | 2008-10-22 | Olympus Corporation | Specific multiplex analysis of nucleic acids |
-
2006
- 2006-08-31 JP JP2008528294A patent/JP2009506759A/ja active Pending
- 2006-08-31 WO PCT/AU2006/001265 patent/WO2007025340A1/en not_active Ceased
- 2006-08-31 EP EP06774894.7A patent/EP1937834B1/en active Active
- 2006-08-31 ES ES06774894.7T patent/ES2494922T3/es active Active
- 2006-08-31 PL PL06774894T patent/PL1937834T3/pl unknown
- 2006-08-31 KR KR1020087007791A patent/KR101515821B1/ko active Active
- 2006-09-01 US US11/515,377 patent/US8962250B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20230038055A1 (en) | Nucleic acid reactions and related methods and compositions | |
| CN106119363B (zh) | 用于抗结核药物肝损伤易感基因型检测的snp组合、检测方法和试剂盒 | |
| Hellyer et al. | Strand displacement amplification: a versatile tool for molecular diagnostics | |
| JP2015156872A5 (cg-RX-API-DMAC10.html) | ||
| JP6723925B2 (ja) | 核酸増幅のための方法およびシステム | |
| JP2009506759A (ja) | 核酸の増幅、定量化、及び同定の方法。 | |
| EP3105324B1 (en) | Ngs systems control and methods involving the same | |
| US9850533B2 (en) | Ligase reaction mediated amplification method and use thereof | |
| Obliosca et al. | LNA thymidine monomer enables differentiation of the four single-nucleotide variants by melting temperature | |
| US20160208240A1 (en) | Ngs workflow | |
| Ma et al. | Ultrafast and highly specific detection of one-base mutated cell-free DNA at a very low abundance | |
| JPWO2017170644A1 (ja) | 遺伝子変異検出法 | |
| Zhang et al. | Single nucleotide polymorphism genotyping of ALDH2 gene based on asymmetric PCR and fluorescent probe-mediated melting curves | |
| US20240352508A1 (en) | Methods, systems and compositions for detection of multiple analytes | |
| JP5916740B2 (ja) | 核酸標的の定量的多重同定 | |
| US20170137807A1 (en) | Improved ngs workflow | |
| Jacobsen et al. | Profiling microRNAs by real-time PCR | |
| JP2022517008A (ja) | 脊髄性筋萎縮症の識別のための方法およびシステム | |
| CN108291254B (zh) | 用于检测单核苷酸多态性的试剂盒和方法 | |
| Zhussupova | PCR–diagnostics | |
| JP2003508074A5 (cg-RX-API-DMAC10.html) | ||
| TWI570242B (zh) | 用於基因型鑑定晶片之雙重等位基因特異性聚合酶鏈鎖反應的方法 | |
| CN101278061B (zh) | 用于扩增、定量和鉴定核酸的方法 | |
| CN102191314A (zh) | 一种基于pcr的低成本、简单、高效的snp检测方法 | |
| JP2009533063A5 (cg-RX-API-DMAC10.html) |