JP2009506301A - Pifファミリーの新たなタンパク質アイソフォーム及びその使用 - Google Patents

Pifファミリーの新たなタンパク質アイソフォーム及びその使用 Download PDF

Info

Publication number
JP2009506301A
JP2009506301A JP2008524596A JP2008524596A JP2009506301A JP 2009506301 A JP2009506301 A JP 2009506301A JP 2008524596 A JP2008524596 A JP 2008524596A JP 2008524596 A JP2008524596 A JP 2008524596A JP 2009506301 A JP2009506301 A JP 2009506301A
Authority
JP
Japan
Prior art keywords
protein
protein isoform
pif
isoform
family
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008524596A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009506301A5 (enExample
Inventor
ロフルフフ クフリスチアン
Original Assignee
オクフォルド ゲノメ スシエンセス (ユーケー) エルティーディー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by オクフォルド ゲノメ スシエンセス (ユーケー) エルティーディー filed Critical オクフォルド ゲノメ スシエンセス (ユーケー) エルティーディー
Publication of JP2009506301A publication Critical patent/JP2009506301A/ja
Publication of JP2009506301A5 publication Critical patent/JP2009506301A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
JP2008524596A 2005-08-04 2006-08-04 Pifファミリーの新たなタンパク質アイソフォーム及びその使用 Pending JP2009506301A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0516058.5A GB0516058D0 (en) 2005-08-04 2005-08-04 New protein isoforms and uses thereof
US72208705P 2005-09-30 2005-09-30
PCT/GB2006/050232 WO2007015113A2 (en) 2005-08-04 2006-08-04 New protein isoforms of the pif-family and uses thereof

Publications (2)

Publication Number Publication Date
JP2009506301A true JP2009506301A (ja) 2009-02-12
JP2009506301A5 JP2009506301A5 (enExample) 2009-09-17

Family

ID=34984093

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008524596A Pending JP2009506301A (ja) 2005-08-04 2006-08-04 Pifファミリーの新たなタンパク質アイソフォーム及びその使用

Country Status (5)

Country Link
US (1) US20100223678A1 (enExample)
EP (1) EP1987356A2 (enExample)
JP (1) JP2009506301A (enExample)
GB (1) GB0516058D0 (enExample)
WO (1) WO2007015113A2 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011033546A (ja) * 2009-08-04 2011-02-17 Hoyu Co Ltd 等電点電気泳動方法及び粗雑物除去の判定方法
JP2011033547A (ja) * 2009-08-04 2011-02-17 Hoyu Co Ltd 2次元電気泳動方法
JP2014527175A (ja) * 2011-08-26 2014-10-09 エフ.ホフマン−ラ ロシュ アーゲー 精神発達、神経または神経精神障害の処置における臨床的有用性を予測するための方法

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2502628B1 (en) 2006-06-23 2016-12-14 Alethia Biotherapeutics Inc. Polynucleotides and polypeptide sequences involved in cancer
WO2010060186A1 (en) 2008-11-03 2010-06-03 Alethia Biotherapeutics Inc. Antibodies that specifically block the biological activity of a tumor antigen
WO2010096331A1 (en) 2009-02-11 2010-08-26 Duke University Sensors incorporating antibodies and methods of making and using the same
DK3173427T3 (da) 2011-03-31 2019-08-05 Adc Therapeutics Sa Antistoffer mod nyre-associeret antigen 1 og antigen-bindende fragmenter deraf
HRP20190946T1 (hr) 2012-01-09 2019-07-26 Adc Therapeutics Sa Sredstva za liječenje trostruko negativnog raka dojke
US9244946B2 (en) 2012-11-26 2016-01-26 International Business Machines Corporation Data mining shape based data
US10407716B2 (en) 2014-03-13 2019-09-10 Duke University Electronic platform for sensing and control of electrochemical reactions

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003029423A2 (en) * 2001-10-02 2003-04-10 Curagen Corporation Therapeutic polypeptides, nucleic acids encoding same, and methods of use
JP2003284574A (ja) * 2001-10-03 2003-10-07 Pfizer Prod Inc 核酸分子、ポリペプチド、ならびにアルツハイマー病の診断および処置を含むそれらの使用
JP2005132738A (ja) * 2003-10-28 2005-05-26 Protein Express:Kk アルツハイマー病のタンパク質分子レベルにおける検出方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6319687B1 (en) * 1992-09-24 2001-11-20 The United States Of America As Represented By The Department Of Health And Human Services Pigment epithelium-derived factor: characterization, genomic organization and sequence of PEDF gene
US6613740B1 (en) * 1997-02-07 2003-09-02 Ramot University Authority For Applied Research And Industrial Development Ltd. Activity dependent neurotrophic factor III (ADNF III)
AU2003235789A1 (en) * 2002-01-11 2003-07-24 Xantos Biomedicine Ag Novel apoptosis-inducing dna sequences
US20090162363A1 (en) * 2003-08-07 2009-06-25 Sofia Patricia Becerra Pedf-r receptor and uses

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003029423A2 (en) * 2001-10-02 2003-04-10 Curagen Corporation Therapeutic polypeptides, nucleic acids encoding same, and methods of use
JP2003284574A (ja) * 2001-10-03 2003-10-07 Pfizer Prod Inc 核酸分子、ポリペプチド、ならびにアルツハイマー病の診断および処置を含むそれらの使用
JP2005132738A (ja) * 2003-10-28 2005-05-26 Protein Express:Kk アルツハイマー病のタンパク質分子レベルにおける検出方法

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011033546A (ja) * 2009-08-04 2011-02-17 Hoyu Co Ltd 等電点電気泳動方法及び粗雑物除去の判定方法
JP2011033547A (ja) * 2009-08-04 2011-02-17 Hoyu Co Ltd 2次元電気泳動方法
JP2014527175A (ja) * 2011-08-26 2014-10-09 エフ.ホフマン−ラ ロシュ アーゲー 精神発達、神経または神経精神障害の処置における臨床的有用性を予測するための方法

Also Published As

Publication number Publication date
GB0516058D0 (en) 2005-09-14
US20100223678A1 (en) 2010-09-02
WO2007015113A3 (en) 2007-12-27
EP1987356A2 (en) 2008-11-05
WO2007015113A2 (en) 2007-02-08

Similar Documents

Publication Publication Date Title
US20070015217A1 (en) Nucleic acid molecules, polypeptides and uses therefor, including diagnosis and treatment of Alzheimer's disease
US20040110938A1 (en) Proteins, genes and their use for diagnosis and treatment of schizophrenia
JP2004532386A (ja) 多発性硬化症を診断および治療するためのタンパク質、遺伝子、およびこれらの使用
JP2009515183A (ja) 新たなタンパク質アイソフォーム及びその使用
EP1408333A2 (en) Diagnosis and treatment of Alzheimer's disease
US20030064411A1 (en) Nucleic acid molecules, polypeptides and uses therefor, including diagnosis and treatment of Alzheimer's disease
US20030152935A1 (en) Proteins, genes and their use for diagnosis and treatment of breast cancer
US20030092614A1 (en) ADPI-41, a novel protein isolated from brain tissue homogenate and uses therefor
JP2009506301A (ja) Pifファミリーの新たなタンパク質アイソフォーム及びその使用
US20020142303A1 (en) Proteins, genes and their use for diagnosis and treatment of Schizophrenia
WO2001063294A2 (en) Diagnosis of bipolar affective disorder (bad) and unipolar depression
US20090258376A1 (en) Protein isoforms and uses thereof
US20030032200A1 (en) Proteins, genes and their use for diagnosis and treatment of bipolar affective disorder (BAD) and unipolar depression
EP1259818A2 (en) Diagnosis and treatment of schizophrenia
EP1264183A2 (en) Diagnosis and treatment of vascular dementia
EP1395828A2 (en) Proteins and genes for diagnosis and treatment of erbb2-related cancer
US20040022794A1 (en) Nucleic acid molecules, polypeptides and uses therefor, including diagnosis and treatment of Alzheimer's disease
US20030092197A1 (en) Proteins, genes and their use for diagnosis and treatment of cardiac response
US20040043425A1 (en) Proteins, genes and their use for diagnosis and treatment of chronic asthma
WO2002054080A2 (en) Proteins, genes and their use for diagnosis and treatment of vascular response

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20090731

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20090731

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20111205

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120313

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20120821