JP2009504791A5 - - Google Patents

Download PDF

Info

Publication number
JP2009504791A5
JP2009504791A5 JP2008527370A JP2008527370A JP2009504791A5 JP 2009504791 A5 JP2009504791 A5 JP 2009504791A5 JP 2008527370 A JP2008527370 A JP 2008527370A JP 2008527370 A JP2008527370 A JP 2008527370A JP 2009504791 A5 JP2009504791 A5 JP 2009504791A5
Authority
JP
Japan
Prior art keywords
formula
compound according
methyl
group
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2008527370A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009504791A (ja
JP5237807B2 (ja
Filing date
Publication date
Priority claimed from GB0517202A external-priority patent/GB0517202D0/en
Priority claimed from GB0517181A external-priority patent/GB0517181D0/en
Application filed filed Critical
Priority claimed from PCT/EP2006/008200 external-priority patent/WO2007022933A1/en
Publication of JP2009504791A publication Critical patent/JP2009504791A/ja
Publication of JP2009504791A5 publication Critical patent/JP2009504791A5/ja
Application granted granted Critical
Publication of JP5237807B2 publication Critical patent/JP5237807B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2008527370A 2005-08-22 2006-08-18 ドーパミンｄ３受容体の調節因子としてのトリアゾール誘導体 Expired - Fee Related JP5237807B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0517181.4 2005-08-22
GB0517202A GB0517202D0 (en) 2005-08-22 2005-08-22 Compounds
GB0517202.8 2005-08-22
GB0517181A GB0517181D0 (en) 2005-08-22 2005-08-22 Compounds
PCT/EP2006/008200 WO2007022933A1 (en) 2005-08-22 2006-08-18 Triazole derivatives as modulators of dopamine d3 receptors

Publications (3)

Publication Number Publication Date
JP2009504791A JP2009504791A (ja) 2009-02-05
JP2009504791A5 true JP2009504791A5 (OSRAM) 2009-10-01
JP5237807B2 JP5237807B2 (ja) 2013-07-17

Family

ID=37309176

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008527370A Expired - Fee Related JP5237807B2 (ja) 2005-08-22 2006-08-18 ドーパミンｄ３受容体の調節因子としてのトリアゾール誘導体

Country Status (6)

Country Link
US (1) US7799815B2 (OSRAM)
EP (1) EP1919908B1 (OSRAM)
JP (1) JP5237807B2 (OSRAM)
AT (1) ATE487715T1 (OSRAM)
DE (1) DE602006018152D1 (OSRAM)
WO (1) WO2007022933A1 (OSRAM)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20100114T1 (hr) * 2004-02-23 2010-04-30 Glaxo Group Limited Derivati azabiciklo[3.1.0]heksana korisni kao modulatori dopaminskih receptora d3
US20070043100A1 (en) 2005-08-16 2007-02-22 Hagen Eric J Novel polymorphs of azabicyclohexane
GB0507602D0 (en) * 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0507601D0 (en) * 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0507680D0 (en) * 2005-04-15 2005-05-25 Glaxo Group Ltd Compounds
GB0512099D0 (en) * 2005-06-14 2005-07-20 Glaxo Group Ltd Compounds
DE602006017543D1 (de) * 2005-06-14 2010-11-25 Glaxo Group Ltd Neue verbindungen
CN101272781A (zh) 2005-07-27 2008-09-24 多夫药品公司 新的1-芳基-3-氮杂二环[3.1.0]己烷：其制备方法和用于治疗神经精神障碍的用途
GB0517187D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517191D0 (en) 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517175D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517193D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Novel use
US8163927B2 (en) * 2006-04-03 2012-04-24 Glaxo Group Limited Azabicyclo [3.1.0] hexane derivatives as modulators of dopamine D3 receptors
WO2007113260A1 (en) * 2006-04-03 2007-10-11 Glaxo Group Limited Azabicyclo [3. 1. o] hexyl derivatives as modulators of dopamine d3 receptors
US20080045725A1 (en) 2006-04-28 2008-02-21 Murry Jerry A Process For The Synthesis of (+) And (-)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane
US8138377B2 (en) 2006-11-07 2012-03-20 Dov Pharmaceutical, Inc. Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use
WO2008153937A2 (en) * 2007-06-06 2008-12-18 Dov Pharmaceutical, Inc. Novel 1- heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
US9133159B2 (en) 2007-06-06 2015-09-15 Neurovance, Inc. 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
CN102803224A (zh) 2009-06-26 2012-11-28 万能药生物有限公司 新的氮杂双环己烷类化合物
US20140206740A1 (en) 2011-07-30 2014-07-24 Neurovance, Inc. Use Of (1R,5S)-(+)-(Napthalen-2-yl)-3-Azabicyclo[3.1.0]Hexane In The Treatment Of Conditions Affected By Monoamine Neurotransmitters
JP7250405B2 (ja) 2018-01-26 2023-04-03 塩野義製薬株式会社 ドーパミンｄ３受容体拮抗作用を有する環式化合物
CN113956157B (zh) * 2021-11-18 2024-05-03 西安都创医药科技有限公司 一种合成2-甲酰基-1-环丙烷甲酸乙酯的方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI244481B (en) * 1998-12-23 2005-12-01 Pfizer 3-azabicyclo[3.1.0]hexane derivatives useful in therapy
TWI274750B (en) * 1999-01-12 2007-03-01 Abbott Gmbh & Co Kg Triazole compounds showing high affinity to dopamine D3 receptor and pharmaceutical composition comprising the same
EP1549639B1 (en) * 2002-10-07 2006-05-24 Glaxo Group Limited Sulphonamide derivatives as antipsychotic agents
DE10304870A1 (de) * 2003-02-06 2004-08-19 Abbott Gmbh & Co. Kg Triazolverbindungen und ihre therapeutische Verwendung
HRP20100114T1 (hr) 2004-02-23 2010-04-30 Glaxo Group Limited Derivati azabiciklo[3.1.0]heksana korisni kao modulatori dopaminskih receptora d3
GB0507601D0 (en) * 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0507602D0 (en) 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0507680D0 (en) * 2005-04-15 2005-05-25 Glaxo Group Ltd Compounds
GB0512099D0 (en) * 2005-06-14 2005-07-20 Glaxo Group Ltd Compounds
DE602006017543D1 (de) * 2005-06-14 2010-11-25 Glaxo Group Ltd Neue verbindungen
GB0517175D0 (en) 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517191D0 (en) 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517187D0 (en) 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517193D0 (en) 2005-08-22 2005-09-28 Glaxo Group Ltd Novel use
ES2434337T3 (es) 2006-04-03 2013-12-16 Glaxo Group Limited Derivados de azabiciclo[3.1.0]hexilo como moduladores de los receptores D3 de la dopamina
GB0616574D0 (en) 2006-08-21 2006-09-27 Glaxo Group Ltd Compounds

Similar Documents

Publication Publication Date Title
JP2009504791A5 (OSRAM)
US9493446B2 (en) Orexin receptor antagonists which are [ortho bi-(hetero-)aryl]-[2-(meta bi-(hetero-)aryl)-pyrrolidin-1-yl]-methanone derivatives
AU2011205283B2 (en) Compounds and methods
JP6503336B2 (ja) シアノトリアゾール化合物
JP2009504794A5 (OSRAM)
JP6853619B2 (ja) シアノトリアゾール化合物の医薬用途
US20100305093A1 (en) Inhibitors of mTOR and Methods of Making and Using
US9926285B2 (en) Allosteric modulators of nicotinic acetylcholine receptors
JP2009504792A5 (OSRAM)
ES2325865T3 (es) Derivados de oxazol como agentes receptores de histamina h3, preparacion y usos terapeuticos.
RU2018138707A (ru) Замещенные гетероарилом пиридины и способы применения
RU2012126083A (ru) Производные аминооксазина
MXPA03003174A (es) Indoles substituidos, composiciones farmaceuticas que contienen dichos indoles y su uso como agentes de enlace ppar-y..
PE20090297A1 (es) Derivados de pirazol sustituidos con heteroarilo utiles para tratar trastornos hiperproliferativos y enfermedades asociadas con angiogenesis
RU2015101102A (ru) Гетероароматическое метильное производное циклического амина
CA2557115A1 (en) Azabicyclo (3.1.0) hexane derivatives useful as modulators of dopamine d3 receptors
JP2015533157A5 (OSRAM)
RU2016111138A (ru) Гетероциклические соединения и способы их применения
JP2011513221A5 (OSRAM)
JP2017519818A5 (OSRAM)
WO2010005572A2 (en) Alpha-keto heterocycles as faah inhibitors
JP2008516922A5 (OSRAM)
RU2014132044A (ru) Гетероциклические производные в качестве рецепторов, ассоциированных со следовыми аминами (taars)
AU2007284599B2 (en) Oxazolidone derivatives as PR modulators
JP2014513122A5 (OSRAM)