JP2009502125A5 - - Google Patents

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Publication number
JP2009502125A5
JP2009502125A5 JP2008521775A JP2008521775A JP2009502125A5 JP 2009502125 A5 JP2009502125 A5 JP 2009502125A5 JP 2008521775 A JP2008521775 A JP 2008521775A JP 2008521775 A JP2008521775 A JP 2008521775A JP 2009502125 A5 JP2009502125 A5 JP 2009502125A5
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Japan
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lysostaphin
expression
coli
sequence
protein
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JP2008521775A
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English (en)
Japanese (ja)
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JP2009502125A (ja
JP5242388B2 (ja
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Priority claimed from CNB2005100280380A external-priority patent/CN100475965C/zh
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JP2008521775A 2005-07-22 2006-07-11 高レベルでの、大腸菌におけるリソスタフィンの分泌発現の方法 Active JP5242388B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN200510028038.0 2005-07-22
CNB2005100280380A CN100475965C (zh) 2005-07-22 2005-07-22 一种大肠杆菌高效外分泌表达溶葡萄球菌酶的方法
PCT/CN2006/001640 WO2007009351A1 (fr) 2005-07-22 2006-07-11 Méthode d'expression à haut niveau de la sécrétion de lysostaphine dans escherichia coli

Publications (3)

Publication Number Publication Date
JP2009502125A JP2009502125A (ja) 2009-01-29
JP2009502125A5 true JP2009502125A5 (https=) 2009-03-19
JP5242388B2 JP5242388B2 (ja) 2013-07-24

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ID=37656277

Family Applications (1)

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JP2008521775A Active JP5242388B2 (ja) 2005-07-22 2006-07-11 高レベルでの、大腸菌におけるリソスタフィンの分泌発現の方法

Country Status (6)

Country Link
US (1) US8241901B2 (https=)
EP (1) EP1918369B1 (https=)
JP (1) JP5242388B2 (https=)
KR (1) KR101098353B1 (https=)
CN (2) CN100475965C (https=)
WO (1) WO2007009351A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
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CN101302504B (zh) * 2007-05-11 2011-12-21 上海高科联合生物技术研发有限公司 一种抗体亲和层析纯化溶葡萄球菌酶的方法
WO2012137187A1 (en) * 2011-04-08 2012-10-11 Anthem Biosciences Pvt Ltd Novel expression and secretion vector systems for heterologous protein production in escherichia coli
WO2014078373A1 (en) * 2012-11-13 2014-05-22 Iogenetics, Llc Antimicrobial compositions
WO2015020765A2 (en) * 2013-08-06 2015-02-12 Trustees Of Dartmouth College Unglycosylated lysostaphin variant protein
CN103509777B (zh) * 2013-09-30 2016-03-30 中国人民解放军军事医学科学院微生物流行病研究所 一种特异定量检测葡萄球菌的方法
WO2015100448A2 (en) 2013-12-28 2015-07-02 Longhorn Vaccines And Diagnostics, Llc Multimodal antimicrobial therapy
EP3116999B1 (en) 2014-03-14 2021-09-15 F. Hoffmann-La Roche AG Methods and compositions for secretion of heterologous polypeptides
KR20170122216A (ko) 2015-03-06 2017-11-03 제넨테크, 인크. 초순수화 dsba 및 dsbc와 이를 제조하고 사용하는 방법
WO2017201036A1 (en) 2016-05-17 2017-11-23 Genentech, Inc. Stromal gene signatures for diagnosis and use in immunotherapy
CN109563124A (zh) 2016-06-17 2019-04-02 豪夫迈·罗氏有限公司 多特异性抗体的纯化
CN107916244A (zh) * 2017-06-20 2018-04-17 江西嘉博生物工程有限公司 一种表达溶葡球菌素基因的重组乳酸乳球菌的构建方法及应用
CN111560048B (zh) * 2020-06-03 2021-08-13 成都正能生物技术有限责任公司 用于提取金黄色葡萄球菌总蛋白的方法及试剂盒
CN112062820B (zh) * 2020-08-24 2023-05-26 黑龙江八一农垦大学 大肠杆菌重组外膜蛋白a包涵体蛋白的复性纯化方法
CN113005134B (zh) * 2021-03-12 2022-06-03 厦门宝太生物科技股份有限公司 一种促进胶质纤维酸性蛋白在大肠杆菌中大量表达的方法
CN114540385B (zh) * 2022-03-21 2023-06-23 齐鲁工业大学 一种利用大肠杆菌产溶葡萄球菌酶的方法
CN115873834B (zh) * 2022-08-26 2024-06-04 山东大学 一种溶葡萄球菌酶变体及其制备方法和应用
CN115975979A (zh) * 2022-10-28 2023-04-18 硅羿科技（上海）有限公司 一种DNaseI的分泌表达方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3278378A (en) 1962-04-19 1966-10-11 Schindler Charles Alvin Staphylococcus-derived antibiotic
US4931390A (en) 1986-04-16 1990-06-05 Public Health Research Institute Of The City Of New York, Inc. Expression of the cloned lysostaphin gene
JP3226289B2 (ja) * 1991-02-13 2001-11-05 株式会社ジャパンエナジー 分泌ベクター、該ベクターで形質転換した微生物及び該微生物から産生される産物の製造法
DE4425645A1 (de) 1994-07-20 1996-02-22 Mueller Karl & Co Kg Deletiertes Lysostaphingen von Staphylococcus simulans
US6132954A (en) * 1996-08-20 2000-10-17 Baylor College Of Medicine Methods of screening for agents that delay a cell cycle and compositions comprising era and an analogue of wild-type era
US6083715A (en) * 1997-06-09 2000-07-04 Board Of Regents, The University Of Texas System Methods for producing heterologous disulfide bond-containing polypeptides in bacterial cells
US6875903B2 (en) * 1998-06-22 2005-04-05 University Of Vermont Treatment of Staphylococcus infections
MXPA02003885A (es) 1999-10-19 2005-06-03 Bharat Biotech International L Expresion de lisostafina madura recombinante.
ES2281409T3 (es) * 2000-02-28 2007-10-01 Novartis Vaccines And Diagnostics S.R.L. Expresion heterologa de proteinas de neisseria.
AU2002241922B2 (en) * 2001-01-17 2007-10-25 Aptevo Research And Development Llc Binding domain-immunoglobulin fusion proteins
KR100968664B1 (ko) * 2001-08-27 2010-07-06 제넨테크, 인크. 항체 발현 및 조립을 위한 시스템
EP1465990B1 (en) * 2001-12-21 2011-07-13 Biosynexus Incorporated Truncated lysostaphin molecule with enhanced staphylolytic activity
EP1482043A4 (en) * 2002-03-01 2005-08-10 Japan Enviro Chemicals Ltd FOR BINDING TO ENVIRONMENTAL MORNES, PROTEINS AND METHOD FOR THE PRODUCTION THEREOF

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