JP2009501938A - サンプルの調製および分析のための微小流動による方法および微小流動装置 - Google Patents

サンプルの調製および分析のための微小流動による方法および微小流動装置 Download PDF

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JP2009501938A
JP2009501938A JP2008522826A JP2008522826A JP2009501938A JP 2009501938 A JP2009501938 A JP 2009501938A JP 2008522826 A JP2008522826 A JP 2008522826A JP 2008522826 A JP2008522826 A JP 2008522826A JP 2009501938 A JP2009501938 A JP 2009501938A
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fluid
microchannel
microfluidic device
polymer
carrier fluid
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JP2009501938A5 (https=
Inventor
グレゴリー アール． ヤンツ，
ジョナサン ダブリュー． ラーソン，
ルドルフ ギルマンシン，
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ユー．エス． ジェノミクス， インコーポレイテッド
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y10/00—Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads or physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502776—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0636—Focussing flows, e.g. to laminate flows
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0663—Stretching or orienting elongated molecules or particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Nanotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Fluid Mechanics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mathematical Physics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Theoretical Computer Science (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
JP2008522826A 2005-07-18 2006-07-13 サンプルの調製および分析のための微小流動による方法および微小流動装置 Withdrawn JP2009501938A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US70049005P 2005-07-18 2005-07-18
US70048005P 2005-07-18 2005-07-18
US70068905P 2005-07-18 2005-07-18
PCT/US2006/027111 WO2007011622A2 (en) 2005-07-18 2006-07-13 Microfluidic methods and apparatuses for sample preparation and analysis

Publications (2)

Publication Number Publication Date
JP2009501938A true JP2009501938A (ja) 2009-01-22
JP2009501938A5 JP2009501938A5 (https=) 2009-08-13

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JP2008522826A Withdrawn JP2009501938A (ja) 2005-07-18 2006-07-13 サンプルの調製および分析のための微小流動による方法および微小流動装置

Country Status (3)

Country Link
EP (1) EP1904653A4 (https=)
JP (1) JP2009501938A (https=)
WO (1) WO2007011622A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013501936A (ja) * 2009-08-12 2013-01-17 カリパー・ライフ・サイエンシズ・インク． 断片化した試料の分別のための挟持チャンネル

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CA2580589C (en) 2006-12-19 2016-08-09 Fio Corporation Microfluidic detection system
WO2009012340A2 (en) * 2007-07-16 2009-01-22 California Institute Of Technology Microfluidic devices, methods and systems for detecting target molecules
US8551763B2 (en) 2007-10-12 2013-10-08 Fio Corporation Flow focusing method and system for forming concentrated volumes of microbeads, and microbeads formed further thereto
WO2009155704A1 (en) 2008-06-25 2009-12-30 Fio Corporation Bio-threat alert system
EP2329278A4 (en) 2008-08-29 2014-05-14 Fio Corp PORTABLE DIAGNOSTIC TEST UNIT FOR ONE-TIME USE AND ASSOCIATED SYSTEM AND METHOD FOR TESTING BIOLOGICAL AND ECOLOGICAL SAMPLES
CN102348986B (zh) 2009-01-13 2015-05-06 Fio公司 与电子设备和快速诊断测试中的测试盒结合使用的手持诊断测试设备和方法
WO2012040098A2 (en) 2010-09-21 2012-03-29 The University Of North Carolina At Chapel Hill Methods, systems and devices for forming nanochannels
WO2013039778A2 (en) 2011-09-12 2013-03-21 The University Of North Carolina At Chapel Hill Devices with a fluid transport nanochannel intersected by a fluid sensing nanochannel and related methods
EP2812708B1 (en) 2012-02-10 2019-09-04 The University of North Carolina At Chapel Hill Method of analysing an analyte with fluidic nanofunnels
US10261065B2 (en) 2013-02-28 2019-04-16 The University Of North Carolina At Chapel Hill Nanofluidic devices with integrated components for the controlled capture, trapping, and transport of macromolecules and related methods of analysis
WO2014164739A1 (en) 2013-03-13 2014-10-09 The University Of North Carolina At Chapel Hill Nanofluidic devices for the rapid mapping of whole genomes and related systems and methods of analysis
EP3295148A4 (en) 2015-05-11 2018-11-07 The University of North Carolina at Chapel Hill Fluidic devices with nanoscale manifolds for molecular transport, related systems and methods of analysis
EP3645167A4 (en) 2017-06-28 2021-02-24 Bio-rad Laboratories, Inc. SYSTEM AND METHOD FOR DROPLET DETECTION
US11045805B2 (en) 2017-11-01 2021-06-29 Bio-Rad Laboratories, Inc. Microfluidic system and method for arranging objects
US10898895B2 (en) 2018-09-13 2021-01-26 Talis Biomedical Corporation Vented converging capillary biological sample port and reservoir
EP3932562A4 (en) * 2019-02-27 2022-12-07 Kyocera Corporation PARTICLE SEPARATION AND MEASURING DEVICE AND PARTICLE SEPARATION AND MEASURING DEVICE

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US4793705A (en) * 1987-10-07 1988-12-27 The United States Of America As Represented By The United States Department Of Energy Single molecule tracking
US5274240A (en) * 1990-01-12 1993-12-28 The Regents Of The University Of California Capillary array confocal fluorescence scanner and method
JP3123249B2 (ja) * 1991-09-10 2001-01-09 株式会社日立製作所 Ｄｎａ分子の長さ計測方法および計測装置
AU673245B2 (en) * 1993-02-01 1996-10-31 Seq, Ltd. Methods and apparatus for DNA sequencing
CN1251609A (zh) * 1997-02-12 2000-04-26 尤金·Y·查恩 分析聚合物的方法和产品
US6790671B1 (en) * 1998-08-13 2004-09-14 Princeton University Optically characterizing polymers
WO2000070080A1 (en) * 1999-05-17 2000-11-23 Caliper Technologies Corp. Focusing of microparticles in microfluidic systems
US6818395B1 (en) * 1999-06-28 2004-11-16 California Institute Of Technology Methods and apparatus for analyzing polynucleotide sequences
US6770182B1 (en) * 2000-11-14 2004-08-03 Sandia National Laboratories Method for producing a thin sample band in a microchannel device
CA2451753A1 (en) * 2001-06-20 2003-01-03 Cytonome, Inc. Microfluidic system including a virtual wall fluid interface port for interfacing fluids with the microfluidic system
US7118910B2 (en) * 2001-11-30 2006-10-10 Fluidigm Corporation Microfluidic device and methods of using same
US7318902B2 (en) * 2002-02-04 2008-01-15 Colorado School Of Mines Laminar flow-based separations of colloidal and cellular particles
EP1380337B1 (en) * 2002-07-12 2012-11-14 Tosoh Corporation Fine channel device and a chemically operating method for fluid using the device
WO2004091795A2 (en) * 2003-04-10 2004-10-28 U.S. Genomics, Inc. Manipulation of polymers in a microchannel

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013501936A (ja) * 2009-08-12 2013-01-17 カリパー・ライフ・サイエンシズ・インク． 断片化した試料の分別のための挟持チャンネル

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WO2007011622A3 (en) 2007-05-24
WO2007011622A2 (en) 2007-01-25
EP1904653A2 (en) 2008-04-02
EP1904653A4 (en) 2010-04-14

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