JP2009501776A - 遊離脂肪酸に起因した障害におけるチアゾール誘導体およびアナログの使用 - Google Patents
遊離脂肪酸に起因した障害におけるチアゾール誘導体およびアナログの使用 Download PDFInfo
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- JP2009501776A JP2009501776A JP2008522065A JP2008522065A JP2009501776A JP 2009501776 A JP2009501776 A JP 2009501776A JP 2008522065 A JP2008522065 A JP 2008522065A JP 2008522065 A JP2008522065 A JP 2008522065A JP 2009501776 A JP2009501776 A JP 2009501776A
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- benzyl
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- trifluoromethyl
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| DE102005024012A1 (de) * | 2005-05-20 | 2006-11-23 | Grünenthal GmbH | Verwendung von 2,5-disubstituierten Thiazol-4-on-Derivaten in Arzneimitteln |
| WO2008065409A2 (en) * | 2006-12-01 | 2008-06-05 | Betagenon Ab | Combination for use in the treatment of cancer, comprising tamoxifen or an aromatase inhibitor |
| WO2008090327A1 (en) * | 2007-01-22 | 2008-07-31 | Betagenon Ab | New combination for use in the treatment of cancer |
| EP2136809A4 (en) * | 2007-03-20 | 2012-01-04 | Curis Inc | INHIBITORS OF RAF KINASE CONTAINING A ZINC BINDING FRAGMENT |
| CN101274918A (zh) * | 2007-03-30 | 2008-10-01 | 中国科学院上海药物研究所 | 一类取代五元杂环化合物,其制备方法和医学用途 |
| AR067770A1 (es) * | 2007-08-03 | 2009-10-21 | Betagenon Ab | Derivados de tiazol y ditiazol para el tratamiento de diabetes |
| AU2008310097B2 (en) | 2007-10-09 | 2013-05-16 | Merck Patent Gmbh | Pyridine derivatives useful as glucokinase activators |
| EP2217235A4 (en) * | 2007-11-15 | 2011-01-12 | Musc Found For Res Dev | INHIBITORS OF PIM PROTEIN KINASES, COMPOSITIONS AND METHOD FOR THE TREATMENT OF CANCER |
| KR100998572B1 (ko) * | 2007-12-14 | 2010-12-07 | 한국생명공학연구원 | 단백질 포스파타제의 활성을 억제하는 페닐아미노티아졸론유도체 또는 이의 약학적으로 허용가능한 염을유효성분으로 함유하는 암 예방 및 치료용 조성물 |
| WO2010073011A2 (en) | 2008-12-23 | 2010-07-01 | Betagenon Ab | Compounds useful as medicaments |
| WO2010086613A1 (en) | 2009-01-30 | 2010-08-05 | Betagenon Ab | Compounds useful as inhibitors as ampk |
| ES2567753T3 (es) | 2009-07-08 | 2016-04-26 | Baltic Bio Ab | Derivados de 1,2,4-tiazolidin-3-ona y su uso en el tratamiento del cáncer |
| US9221773B2 (en) * | 2009-12-22 | 2015-12-29 | The Translational Genomics Research Institute | Benzamide derivatives |
| WO2012118935A1 (en) | 2011-03-03 | 2012-09-07 | Proteotech Inc | Compounds for the treatment of neurodegenerative diseases |
| WO2013049119A1 (en) * | 2011-09-30 | 2013-04-04 | Bristol-Myers Squibb Company | Selective nr2b antagonists |
| WO2013108026A1 (en) | 2012-01-17 | 2013-07-25 | Baltic Bio Ab | Thiadiazolone derivatives useful in the treatment of diabetes |
| CN104059060B (zh) * | 2014-05-30 | 2017-08-01 | 西安交通大学 | 一种5‑(1h‑吲哚‑3‑亚甲基)‑1,3‑噻唑烷‑4‑酮类衍生物及其合成方法和应用 |
| EP4013744A1 (de) * | 2019-08-15 | 2022-06-22 | Bayer Aktiengesellschaft | Verfahren zur herstellung von 2-(phenylimino)-3-alkyl-1,3-thiazolidin-4-onen |
| WO2023111996A1 (en) | 2021-12-17 | 2023-06-22 | Reglagene Holding, Inc. | Compositions and methods of making and using small molecules in the treatment of cancer |
| US12215102B2 (en) | 2023-02-28 | 2025-02-04 | Reglagene, Inc. | Compositions and methods for making and using small molecules for tubulin-targeted therapy in the treatment of cancers and related conditions |
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| US3345374A (en) * | 1962-09-04 | 1967-10-03 | Bayer Ag | Certain oxathiazole and dithiazole derivatives |
| US3671537A (en) * | 1969-06-05 | 1972-06-20 | Gyogyszerkutato Intezet | Certain 3-(2,6-dichlorophenyl)-2-iminothiazolidines |
| US4103018A (en) * | 1976-10-12 | 1978-07-25 | Schering Corporation | 2-[4-(Polyhalo-2-hydroxy-2-propyl)anilino]-2-oxazolin-4-ones and thiazolin-4-ones corresponding thereto |
| HU191408B (en) * | 1984-04-25 | 1987-02-27 | Egis Gyogyszergyar,Hu | Process for preparing new imino-thiazolidine derivatives |
| DD246541A1 (de) * | 1986-01-27 | 1987-06-10 | Univ Halle Wittenberg | Verfahren zur herstellung von 5-arylidenthiazolidin-4-onen |
| DD270072A1 (de) * | 1988-03-14 | 1989-07-19 | Univ Halle Wittenberg | Verfahren zur herstellung von 5-aryliden- hoch 2-thiazolin-4-onen |
| US6353006B1 (en) * | 1999-01-14 | 2002-03-05 | Bayer Corporation | Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents |
| AU2003282980A1 (en) * | 2002-10-23 | 2004-05-13 | Beyond Genomics, Inc. | 4-alkenylthiazoles comprising epoxide functionality, and methods of use thereof |
| WO2005082363A1 (en) * | 2004-02-20 | 2005-09-09 | Board Of Regents, The University Of Texas System | Thiazolone compounds for treatment of cancer |
| EP1747218A2 (en) * | 2004-04-30 | 2007-01-31 | Schering Corporation | Neuropeptide receptor modulators |
| AU2005259512A1 (en) * | 2004-07-01 | 2006-01-12 | F. Hoffmann-La Roche Ag | Thiazolinone unsubstituted quinolines |
| EP1776112A4 (en) * | 2004-08-10 | 2009-11-25 | Exelixis Inc | HETEROCYCLIC COMPOUNDS AS PHARMACEUTICAL AGENTS |
| RU2405782C2 (ru) * | 2004-10-14 | 2010-12-10 | Ф.Хоффманн-Ля Рош Аг | Хиназолинилметилентиазолиноны в качестве cdk-1 ингибиторов |
| CN100525929C (zh) * | 2005-04-20 | 2009-08-12 | 郭文礼 | 喷水枪出水控制装置 |
| JP2009500351A (ja) * | 2005-07-04 | 2009-01-08 | ドクター レディズ ラボラトリーズ リミテッド | Ａｍｐｋアクチベータとしてのチアゾール誘導体 |
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| AU2006271383A1 (en) | 2007-01-25 |
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| WO2007010281A2 (en) | 2007-01-25 |
| EA200800302A1 (ru) | 2008-08-29 |
| WO2007010273A2 (en) | 2007-01-25 |
| CA2615752A1 (en) | 2007-01-25 |
| EP1906956A2 (en) | 2008-04-09 |
| IL188031A0 (en) | 2011-08-01 |
| NO20076420L (no) | 2008-04-09 |
| KR20080034436A (ko) | 2008-04-21 |
| US20090136472A1 (en) | 2009-05-28 |
| EP1906955A2 (en) | 2008-04-09 |
| AU2006271375A2 (en) | 2007-01-25 |
| IL188163A0 (en) | 2008-03-20 |
| AU2006271375A1 (en) | 2007-01-25 |
| WO2007010281A3 (en) | 2007-06-07 |
| CA2614327A1 (en) | 2007-01-25 |
| US20090156644A1 (en) | 2009-06-18 |
| WO2007010273A3 (en) | 2007-05-10 |
| KR20080032096A (ko) | 2008-04-14 |
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