JP2008546397A5 - - Google Patents
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- JP2008546397A5 JP2008546397A5 JP2008517346A JP2008517346A JP2008546397A5 JP 2008546397 A5 JP2008546397 A5 JP 2008546397A5 JP 2008517346 A JP2008517346 A JP 2008517346A JP 2008517346 A JP2008517346 A JP 2008517346A JP 2008546397 A5 JP2008546397 A5 JP 2008546397A5
- Authority
- JP
- Japan
- Prior art keywords
- stem cells
- adipose tissue
- derived stromal
- markers
- stromal stem
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 210000000130 stem cell Anatomy 0.000 claims description 20
- 210000000577 adipose tissue Anatomy 0.000 claims description 18
- 239000000203 mixture Substances 0.000 claims description 10
- 230000000735 allogeneic effect Effects 0.000 claims description 6
- 210000004027 cell Anatomy 0.000 claims description 3
- -1 CD49A Proteins 0.000 claims 8
- 239000008194 pharmaceutical composition Substances 0.000 claims 7
- 102100031573 Hematopoietic progenitor cell antigen CD34 Human genes 0.000 claims 6
- 101000777663 Homo sapiens Hematopoietic progenitor cell antigen CD34 Proteins 0.000 claims 6
- 101000800116 Homo sapiens Thy-1 membrane glycoprotein Proteins 0.000 claims 6
- 102100033523 Thy-1 membrane glycoprotein Human genes 0.000 claims 6
- 102100035248 Alpha-(1,3)-fucosyltransferase 4 Human genes 0.000 claims 4
- 102100022749 Aminopeptidase N Human genes 0.000 claims 4
- 102100032912 CD44 antigen Human genes 0.000 claims 4
- 102100022002 CD59 glycoprotein Human genes 0.000 claims 4
- 102100037904 CD9 antigen Human genes 0.000 claims 4
- 102100025680 Complement decay-accelerating factor Human genes 0.000 claims 4
- 102100037241 Endoglin Human genes 0.000 claims 4
- 101001022185 Homo sapiens Alpha-(1,3)-fucosyltransferase 4 Proteins 0.000 claims 4
- 101000757160 Homo sapiens Aminopeptidase N Proteins 0.000 claims 4
- 101000868273 Homo sapiens CD44 antigen Proteins 0.000 claims 4
- 101000897400 Homo sapiens CD59 glycoprotein Proteins 0.000 claims 4
- 101000738354 Homo sapiens CD9 antigen Proteins 0.000 claims 4
- 101000856022 Homo sapiens Complement decay-accelerating factor Proteins 0.000 claims 4
- 101000881679 Homo sapiens Endoglin Proteins 0.000 claims 4
- 101000994365 Homo sapiens Integrin alpha-6 Proteins 0.000 claims 4
- 101001046686 Homo sapiens Integrin alpha-M Proteins 0.000 claims 4
- 101001046677 Homo sapiens Integrin alpha-V Proteins 0.000 claims 4
- 101000935043 Homo sapiens Integrin beta-1 Proteins 0.000 claims 4
- 101001015006 Homo sapiens Integrin beta-4 Proteins 0.000 claims 4
- 101000599852 Homo sapiens Intercellular adhesion molecule 1 Proteins 0.000 claims 4
- 101000599858 Homo sapiens Intercellular adhesion molecule 2 Proteins 0.000 claims 4
- 101000917858 Homo sapiens Low affinity immunoglobulin gamma Fc region receptor III-A Proteins 0.000 claims 4
- 101000917839 Homo sapiens Low affinity immunoglobulin gamma Fc region receptor III-B Proteins 0.000 claims 4
- 101001063392 Homo sapiens Lymphocyte function-associated antigen 3 Proteins 0.000 claims 4
- 101000946889 Homo sapiens Monocyte differentiation antigen CD14 Proteins 0.000 claims 4
- 101000738771 Homo sapiens Receptor-type tyrosine-protein phosphatase C Proteins 0.000 claims 4
- 101000622304 Homo sapiens Vascular cell adhesion protein 1 Proteins 0.000 claims 4
- 102100032816 Integrin alpha-6 Human genes 0.000 claims 4
- 102100022338 Integrin alpha-M Human genes 0.000 claims 4
- 102100022337 Integrin alpha-V Human genes 0.000 claims 4
- 102100025304 Integrin beta-1 Human genes 0.000 claims 4
- 102100033000 Integrin beta-4 Human genes 0.000 claims 4
- 102100037877 Intercellular adhesion molecule 1 Human genes 0.000 claims 4
- 102100037872 Intercellular adhesion molecule 2 Human genes 0.000 claims 4
- 102100029185 Low affinity immunoglobulin gamma Fc region receptor III-B Human genes 0.000 claims 4
- 102100030984 Lymphocyte function-associated antigen 3 Human genes 0.000 claims 4
- 102100035877 Monocyte differentiation antigen CD14 Human genes 0.000 claims 4
- 102000003729 Neprilysin Human genes 0.000 claims 4
- 108090000028 Neprilysin Proteins 0.000 claims 4
- 102100024616 Platelet endothelial cell adhesion molecule Human genes 0.000 claims 4
- 102100037422 Receptor-type tyrosine-protein phosphatase C Human genes 0.000 claims 4
- 102100023543 Vascular cell adhesion protein 1 Human genes 0.000 claims 4
- 102000007469 Actins Human genes 0.000 claims 2
- 108010085238 Actins Proteins 0.000 claims 2
- 102100036912 Desmin Human genes 0.000 claims 2
- 108010044052 Desmin Proteins 0.000 claims 2
- 102000001690 Factor VIII Human genes 0.000 claims 2
- 108010054218 Factor VIII Proteins 0.000 claims 2
- 102000011782 Keratins Human genes 0.000 claims 2
- 108010076876 Keratins Proteins 0.000 claims 2
- 102000016971 Proto-Oncogene Proteins c-kit Human genes 0.000 claims 2
- 108010014608 Proto-Oncogene Proteins c-kit Proteins 0.000 claims 2
- 102000013127 Vimentin Human genes 0.000 claims 2
- 108010065472 Vimentin Proteins 0.000 claims 2
- 239000000853 adhesive Substances 0.000 claims 2
- 230000001070 adhesive effect Effects 0.000 claims 2
- 210000005045 desmin Anatomy 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 206010015037 epilepsy Diseases 0.000 claims 2
- 229960000301 factor viii Drugs 0.000 claims 2
- 210000005048 vimentin Anatomy 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 1
- 241000124008 Mammalia Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 210000001185 bone marrow Anatomy 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 210000002536 stromal cell Anatomy 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/167,061 US20060045872A1 (en) | 2004-08-25 | 2005-06-24 | Use of adipose tissue-derived stromal stem cells in treating fistula |
| PCT/EP2006/004605 WO2006136244A2 (en) | 2005-06-24 | 2006-05-16 | Use of adipose tissue-derived stromal stem cells in treating fistula |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013218552A Division JP6289858B2 (ja) | 2005-06-24 | 2013-10-21 | 瘻の治療における脂肪組織由来間質幹細胞の使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008546397A JP2008546397A (ja) | 2008-12-25 |
| JP2008546397A5 true JP2008546397A5 (cg-RX-API-DMAC7.html) | 2012-07-26 |
Family
ID=37116048
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008517346A Pending JP2008546397A (ja) | 2005-06-24 | 2006-05-16 | 瘻の治療における脂肪組織由来間質幹細胞の使用 |
| JP2013218552A Active JP6289858B2 (ja) | 2005-06-24 | 2013-10-21 | 瘻の治療における脂肪組織由来間質幹細胞の使用 |
| JP2016000288A Active JP6545624B2 (ja) | 2005-06-24 | 2016-01-04 | 瘻の治療における脂肪組織由来間質幹細胞の使用 |
| JP2019018275A Active JP6812475B2 (ja) | 2005-06-24 | 2019-02-04 | 瘻の治療における脂肪組織由来間質幹細胞の使用 |
| JP2020088068A Active JP7027484B2 (ja) | 2005-06-24 | 2020-05-20 | 瘻の治療における脂肪組織由来間質幹細胞の使用 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013218552A Active JP6289858B2 (ja) | 2005-06-24 | 2013-10-21 | 瘻の治療における脂肪組織由来間質幹細胞の使用 |
| JP2016000288A Active JP6545624B2 (ja) | 2005-06-24 | 2016-01-04 | 瘻の治療における脂肪組織由来間質幹細胞の使用 |
| JP2019018275A Active JP6812475B2 (ja) | 2005-06-24 | 2019-02-04 | 瘻の治療における脂肪組織由来間質幹細胞の使用 |
| JP2020088068A Active JP7027484B2 (ja) | 2005-06-24 | 2020-05-20 | 瘻の治療における脂肪組織由来間質幹細胞の使用 |
Country Status (23)
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8455458B2 (en) | 2002-10-16 | 2013-06-04 | Arthrodynamic Technologies, Animal Health Division, Inc. | Composition and method for treating connective tissue damage |
| US7803787B2 (en) * | 2002-10-16 | 2010-09-28 | Arthrodynamic Technologies, Animal Health Division, Inc. | Composition and method for treating connective tissue damage by transmucosal administration |
| US20060045872A1 (en) * | 2004-08-25 | 2006-03-02 | Universidad Autonoma De Madrid Ciudad Universitaria de Cantoblanco | Use of adipose tissue-derived stromal stem cells in treating fistula |
| AU2006244479B2 (en) | 2005-05-05 | 2012-08-09 | Nyse Group, Inc. | Unpriced order auction and routing |
| US20070027543A1 (en) * | 2005-08-01 | 2007-02-01 | Gimble Jeffrey M | Use of adipose tissue-derived stromal cells in spinal fusion |
| PT1926813T (pt) | 2005-09-23 | 2016-09-06 | Consejo Superior Investigacion | Populações de células que têm atividade imunorreguladora, método para isolamento e usos |
| JP5131833B2 (ja) * | 2005-10-05 | 2013-01-30 | 晃文 松山 | 脂肪組織由来細胞から膵内分泌細胞を得る方法 |
| CA2630452C (en) * | 2005-12-02 | 2011-02-22 | Cook Incorporated | Devices, systems, and methods for occluding a defect |
| US20090209031A1 (en) * | 2006-01-26 | 2009-08-20 | Tyco Healthcare Group Lp | Medical device package |
| EP1984488B1 (en) * | 2006-01-30 | 2017-12-27 | University Of Virginia Patent Foundation | Methods of preparing and characterizing mesenchymal stem cell aggregates and uses thereof |
| US20070224173A1 (en) * | 2006-03-21 | 2007-09-27 | Koullick Edouard A | Nonexpansion Protocol for Autologous Cell-Based Therapies |
| US8021882B2 (en) | 2006-08-24 | 2011-09-20 | Johnstone Brian H | Production of neural protective and regenerative factors from stem cells and treatment of nervous system conditions therewith |
| AU2007320031B2 (en) * | 2006-10-06 | 2013-05-02 | University Of Virginia Patent Foundation | Methods and compositions useful for diabetic wound healing |
| KR20080103637A (ko) | 2007-05-25 | 2008-11-28 | 주식회사 알앤엘바이오 | 지방유래 줄기세포를 함유하는 사지말단부 허혈성 질환의세포치료용 조성물 |
| US9186375B2 (en) | 2007-06-21 | 2015-11-17 | Arthrodynamic Technologies, Animal Health Division, Inc. | Glycosaminoglycan compositions in combination with stem cells |
| AU2014227541B2 (en) * | 2007-09-19 | 2015-10-01 | Pluristem Ltd. | Methods of Treating Inflammatory Colon Diseases |
| CN102123717A (zh) * | 2008-05-27 | 2011-07-13 | 普拉里斯坦有限公司 | 治疗炎性结肠疾病的方法 |
| WO2009152084A2 (en) * | 2008-06-11 | 2009-12-17 | Cell4Vet Llc | Adipose tissue-derived stem cells for veterinary use |
| JP5763535B2 (ja) | 2008-06-24 | 2015-08-12 | バイオアクティブ サージカル インコーポレイテッド | 幹細胞または他の生理活性材料が組み込まれた外科手術用縫合糸 |
| US20100098739A1 (en) * | 2008-10-20 | 2010-04-22 | University Of Virginia Patent Foundation | Compositions and methods for modular soft tissue repair |
| US20100112696A1 (en) * | 2008-11-03 | 2010-05-06 | Baxter International Inc. | Apparatus And Methods For Processing Tissue To Release Cells |
| US8309343B2 (en) | 2008-12-01 | 2012-11-13 | Baxter International Inc. | Apparatus and method for processing biological material |
| JP5647230B2 (ja) * | 2009-04-28 | 2014-12-24 | アントロジェン カンパニー リミテッドＡｎｔｅｒｏｇｅｎ Ｃｏ．， Ｌｔｄ． | 瘻孔治療のための自家及び同種異系の脂肪由来間質幹細胞組成物 |
| US8883210B1 (en) | 2010-05-14 | 2014-11-11 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US9352003B1 (en) | 2010-05-14 | 2016-05-31 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US10130736B1 (en) | 2010-05-14 | 2018-11-20 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US9669200B2 (en) | 2010-08-06 | 2017-06-06 | Boston Scientific Scimed, Inc. | Systems and methods for the treatment of pelvic disorders including magnetic particulates |
| US20120087933A1 (en) | 2010-10-08 | 2012-04-12 | Samson Tom | Enhanced msc preparations |
| US9180172B2 (en) | 2010-12-15 | 2015-11-10 | Ams Research Corporation | Treatment of Peyronies disease |
| US8979797B2 (en) | 2010-12-16 | 2015-03-17 | Ams Research Corporation | High pressure delivery system and method for treating pelvic disorder using large molecule therapeutics |
| US20140154274A1 (en) | 2011-01-12 | 2014-06-05 | Tigenix Nv | Methods and compositions for use in intralymphatic cellular therapies |
| KR20140016933A (ko) | 2011-03-11 | 2014-02-10 | 타이제닉스, 에스.에이.유. | 면역조절 활성을 갖는 세포군, 분리방법 및 용도들 |
| US8834928B1 (en) | 2011-05-16 | 2014-09-16 | Musculoskeletal Transplant Foundation | Tissue-derived tissugenic implants, and methods of fabricating and using same |
| CL2011001904A1 (es) * | 2011-08-08 | 2012-03-09 | Univ Pontificia Catolica Chile | Formulacion farmaceutica que comprende celulas madres mesenquimales vivas suspendidas en un vehiculo farmaceuticamente aceptable, sistema de aplicacion topica en aerosol que las comprende; y su uso para tratar heridas. |
| US20130072903A1 (en) * | 2011-09-20 | 2013-03-21 | John Chapman | Adipose Tissue Graft for Wound Healing |
| GB201202319D0 (en) * | 2012-02-10 | 2012-03-28 | Orbsen Therapeutics Ltd | Stromal stem cells |
| US20140024011A1 (en) * | 2012-07-23 | 2014-01-23 | AdiCyte, Inc. | Method for Preparing Adipose Tissue |
| DK2908871T3 (en) * | 2012-10-18 | 2018-12-03 | Mayo Found Medical Education & Res | METHODS OF TREATING ABSTRACTS |
| WO2014186854A1 (pt) * | 2013-05-24 | 2014-11-27 | Universidade Estadual De Campinas - Unicamp | Processo de obtenção de fio de sutura enriquecido com celulas-tronco, fios obtidos, kit de sutura e seus usos |
| CA2919374C (en) | 2013-07-30 | 2019-12-03 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
| WO2016086147A1 (en) * | 2014-11-26 | 2016-06-02 | Millennium Pharmaceuticals, Inc. | Vedolizumab for the treatment of fistulizing crohn's disease |
| RU2588835C1 (ru) * | 2014-11-27 | 2016-07-10 | Олег Германович Макеев | Способ терапии повреждений кожи и биотрансплантат для его осуществления |
| WO2016187413A1 (en) | 2015-05-21 | 2016-11-24 | Musculoskeletal Transplant Foundation | Modified demineralized cortical bone fibers |
| US10912864B2 (en) | 2015-07-24 | 2021-02-09 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
| US11052175B2 (en) | 2015-08-19 | 2021-07-06 | Musculoskeletal Transplant Foundation | Cartilage-derived implants and methods of making and using same |
| SI3365432T1 (sl) | 2015-10-23 | 2020-08-31 | Rigshospitalet | Terapija z matičnimi celicami, na osnovi matičnih celic iz adipoze |
| GB201604304D0 (en) | 2016-03-14 | 2016-04-27 | Tigenix S A U | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| WO2018011192A1 (en) * | 2016-07-12 | 2018-01-18 | Centre National De La Recherche Scientifique | Compositions useful for mucosal healing |
| IT201700043316A1 (it) * | 2017-04-20 | 2018-10-20 | Lipogems Int S P A | Drug delivery system |
| JP6999918B2 (ja) | 2017-08-21 | 2022-02-04 | 学校法人慶應義塾 | 血小板表面抗原と間葉系細胞表面抗原を共発現する血小板様細胞を含む創傷治癒促進剤 |
| WO2019102268A1 (en) | 2017-11-22 | 2019-05-31 | Mesoblast International Sarl | Cellular compositions and methods of treatment i |
| US11116737B1 (en) | 2020-04-10 | 2021-09-14 | University Of Georgia Research Foundation, Inc. | Methods of using probenecid for treatment of coronavirus infections |
| CN111840645B (zh) * | 2020-07-29 | 2022-04-01 | 沈阳细胞治疗工程技术研发中心有限公司 | 一种瘘洞修补制剂及其制备方法 |
| CN115103696B (zh) * | 2020-12-24 | 2024-07-09 | 罗基医疗保健公司 | 用于构建组织再生贴片的方法 |
| CN114949361A (zh) * | 2021-12-31 | 2022-08-30 | 浙江金时代生物技术有限公司 | 一种用于子宫内膜修复的聚乳酸-羟基乙酸共聚物支架与人脐带间充质干细胞复合物的制备方法 |
| WO2024227193A2 (en) * | 2023-04-28 | 2024-10-31 | Angiocrine Bioscience, Inc. | Endothelial cells for treatment of gastrointestinal fistula |
Family Cites Families (78)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4298002A (en) | 1979-09-10 | 1981-11-03 | National Patent Development Corporation | Porous hydrophilic materials, chambers therefrom, and devices comprising such chambers and biologically active tissue and methods of preparation |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5143842A (en) | 1988-11-01 | 1992-09-01 | The University Of Colorado Foundation, Inc. | Media for normal human muscle satellite cells |
| US5145770A (en) * | 1990-06-04 | 1992-09-08 | Biosurface Technology, Inc. | Cryopreservation of cultured epithelial sheets |
| US5149543A (en) | 1990-10-05 | 1992-09-22 | Massachusetts Institute Of Technology | Ionically cross-linked polymeric microcapsules |
| US6010696A (en) * | 1990-11-16 | 2000-01-04 | Osiris Therapeutics, Inc. | Enhancing hematopoietic progenitor cell engraftment using mesenchymal stem cells |
| US5486359A (en) | 1990-11-16 | 1996-01-23 | Osiris Therapeutics, Inc. | Human mesenchymal stem cells |
| US5733542A (en) | 1990-11-16 | 1998-03-31 | Haynesworth; Stephen E. | Enhancing bone marrow engraftment using MSCS |
| EP0662882B1 (de) | 1992-10-10 | 1998-01-07 | HEMSCHEIDT FAHRWERKTECHNIK GmbH & Co. | Hydropneumatisches federungssystem |
| HUT71914A (en) | 1992-12-02 | 1996-02-28 | Shell Int Research | Azoxycyanobenzene-derivatives, process for their preparation, fungicidal compositions containing them |
| US5709854A (en) * | 1993-04-30 | 1998-01-20 | Massachusetts Institute Of Technology | Tissue formation by injecting a cell-polymeric solution that gels in vivo |
| WO1995002698A1 (en) | 1993-07-12 | 1995-01-26 | Life Technologies, Inc. | Composition and methods for transfecting eukaryotic cells |
| US6174333B1 (en) * | 1994-06-06 | 2001-01-16 | Osiris Therapeutics, Inc. | Biomatrix for soft tissue regeneration using mesenchymal stem cells |
| EP0952792B1 (en) * | 1994-06-06 | 2003-08-27 | Case Western Reserve University | Biomatrix for tissue regeneration |
| DE69634084T2 (de) | 1995-06-07 | 2005-12-08 | Inex Pharmaceuticals Corp. | Herstellung von lipid-nukleinsäure partikeln duch ein hydrophobische lipid-nukleinsäuree komplexe zwischenprodukt und zur verwendung in der gentransfer |
| US6051429A (en) | 1995-06-07 | 2000-04-18 | Life Technologies, Inc. | Peptide-enhanced cationic lipid transfections |
| AU723003C (en) | 1995-08-04 | 2004-01-29 | General Hospital Corporation, The | Transgenic swine and swine cells having human HLA genes |
| US5744335A (en) | 1995-09-19 | 1998-04-28 | Mirus Corporation | Process of transfecting a cell with a polynucleotide mixed with an amphipathic compound and a DNA-binding protein |
| US5705308A (en) | 1996-09-30 | 1998-01-06 | Eastman Kodak Company | Infrared-sensitive, negative-working diazonaphthoquinone imaging composition and element |
| WO1998031316A1 (en) * | 1997-01-17 | 1998-07-23 | Celadon Science, Llc | Methods for promoting healing of corneal resurfacing wounds |
| AU1615599A (en) | 1997-12-02 | 1999-06-16 | Zen Bio, Inc. | Differentiation of adipose stromal cells into osteoblasts and uses thereof |
| JP2002502824A (ja) | 1998-02-04 | 2002-01-29 | ザ・ジェネラル・ホスピタル・コーポレイション | 同種移植における補刺激遮断および混合キメラ現象 |
| US6368636B1 (en) * | 1998-03-18 | 2002-04-09 | Osiris Therapeutics, Inc. | Mesenchymal stem cells for prevention and treatment of immune responses in transplantation |
| US9585916B2 (en) | 1999-03-26 | 2017-03-07 | Northern Therapeutics Inc. | Cell based therapy for the pulmonary system |
| DK1066060T3 (da) | 1998-04-03 | 2003-11-24 | Osiris Therapeutics Inc | Mesenkymale stamceller som immunsuppresive midler |
| US6546105B1 (en) | 1998-10-30 | 2003-04-08 | Matsushita Electric Industrial Co., Ltd. | Sound image localization device and sound image localization method |
| US6777231B1 (en) | 1999-03-10 | 2004-08-17 | The Regents Of The University Of California | Adipose-derived stem cells and lattices |
| US20050153442A1 (en) * | 1999-03-10 | 2005-07-14 | Adam Katz | Adipose-derived stem cells and lattices |
| US20030082152A1 (en) * | 1999-03-10 | 2003-05-01 | Hedrick Marc H. | Adipose-derived stem cells and lattices |
| BR0008552A (pt) | 1999-03-10 | 2002-05-07 | Univ Pittsburgh | Células tronco e redes derivadas de tecido adiposo |
| WO2000073418A2 (en) * | 1999-05-28 | 2000-12-07 | Pacgen Technologies Llc | A method of using autologous fibroblasts to promote healing of wounds and fistulas |
| US7670628B2 (en) | 1999-07-07 | 2010-03-02 | Angioblast Systems, Inc. | Mesenchymal precursor cell |
| US6555374B1 (en) | 1999-08-19 | 2003-04-29 | Artecel Sciences, Inc. | Multiple mesodermal lineage differentiation potentials for adipose tissue-derived stromal cells and uses thereof |
| US7078232B2 (en) * | 1999-08-19 | 2006-07-18 | Artecel, Inc. | Adipose tissue-derived adult stem or stromal cells for the repair of articular cartilage fractures and uses thereof |
| JP2003523323A (ja) | 1999-12-06 | 2003-08-05 | ザ ジェネラル ホスピタル コーポレーション | 膵臓幹細胞および移植におけるその使用 |
| EP1372398B1 (en) | 2001-02-23 | 2013-07-10 | The University of Pittsburgh | Rapid preparation of stem cell matrices for use in tissue and organ treatement and repair |
| US20030054331A1 (en) | 2001-09-14 | 2003-03-20 | Stemsource, Inc. | Preservation of non embryonic cells from non hematopoietic tissues |
| JP2005508393A (ja) | 2001-11-09 | 2005-03-31 | アーテセル・サイエンシズ・インコーポレーテツド | 胚および成人幹細胞をサポートするための間質細胞の使用の方法および組成物 |
| EP1461053A2 (en) * | 2001-12-04 | 2004-09-29 | Christopher J. Woolverton | Storage-stable fibrin sealant |
| US7771716B2 (en) | 2001-12-07 | 2010-08-10 | Cytori Therapeutics, Inc. | Methods of using regenerative cells in the treatment of musculoskeletal disorders |
| US20050118714A1 (en) * | 2002-02-19 | 2005-06-02 | Chul-Won Ha | Isolation and culture-expansion methods of mesenchymal stem/progenitor cells from umbilical cord blood and differentation method of umbilical cord blood-derived mesenchymal stem/progenitor cells into various mesenchymal tissues |
| EP1499347A2 (en) | 2002-03-15 | 2005-01-26 | Department of Veterans Affairs, Rehabilitation R&D Service | Methods and compositions using cellular asialodeterminants and glycoconjugates for targeting cells to tissues and organs |
| US20040009534A1 (en) * | 2002-06-14 | 2004-01-15 | Dyax Corporation | Protein analysis |
| ATE384079T1 (de) | 2002-06-14 | 2008-02-15 | Cartela Ab | Marker für stammzellen und dessen verwendung |
| US20040101959A1 (en) * | 2002-11-21 | 2004-05-27 | Olga Marko | Treatment of tissue with undifferentiated mesenchymal cells |
| JP2004190976A (ja) * | 2002-12-12 | 2004-07-08 | Sony Corp | 熱輸送装置及び電子デバイス |
| CA2515594A1 (en) * | 2003-02-13 | 2004-08-26 | Anthrogenesis Corporation | Use of umbilical cord blood to treat individuals having a disease, disorder or condition |
| EP1608411B1 (en) | 2003-04-01 | 2010-09-29 | United States Government as represented by the Department of Veteran's Affaires | Stem-cell, precursor cell, or target cell-based treatment of multi-organ failure. |
| ES2265199B1 (es) | 2003-06-12 | 2008-02-01 | Cellerix, S.L. | Celulas madre adultas multipotentes procedentes de condrocitos desdiferenciados y sus aplicaciones. |
| PL1641916T3 (pl) | 2003-06-27 | 2016-08-31 | Depuy Synthes Products Inc | Regeneracja i naprawa tkanki nerwowej z wykorzystaniem komórek poporodowych |
| US7645229B2 (en) * | 2003-09-26 | 2010-01-12 | Armstrong David N | Instrument and method for endoscopic visualization and treatment of anorectal fistula |
| US9074190B2 (en) | 2003-10-07 | 2015-07-07 | Biomaster, Inc. | Cell differentiation of adipose-derived precursor cells |
| EP1692275B1 (en) | 2003-11-04 | 2010-12-29 | Biomaster, Inc. | Method and system for preparing stem cells from fat tissue |
| WO2005062857A2 (en) | 2003-12-24 | 2005-07-14 | The Trustees Of Columbia University In The City Of New York | Creation of a biological atrioventricular bypass to compensate for atrioventricular block |
| US20080095749A1 (en) | 2004-03-22 | 2008-04-24 | Sudeepta Aggarwal | Mesenchymal stem cells and uses therefor |
| US20050239897A1 (en) | 2004-03-22 | 2005-10-27 | Pittenger Mark F | Mesenchymal stem cells and uses therefor |
| RU2252252C1 (ru) | 2004-04-09 | 2005-05-20 | Тепляшин Александр Сергеевич | Способ выделения мезенхимальных стволовых клеток |
| US20060045872A1 (en) * | 2004-08-25 | 2006-03-02 | Universidad Autonoma De Madrid Ciudad Universitaria de Cantoblanco | Use of adipose tissue-derived stromal stem cells in treating fistula |
| ES2313805B1 (es) | 2004-10-04 | 2009-12-23 | Cellerix, S.L. | Identificacion y aislamiento de celulas multipotentes de tejido mesenquimal no osteocondral. |
| ES2264862B8 (es) | 2004-08-25 | 2017-01-20 | Cellerix, S.L. | Biomaterial para sutura. |
| WO2006029347A2 (en) | 2004-09-03 | 2006-03-16 | University Of Maryland, Baltimore | Integrin cd18 is a novel stromal stem cell marker and functions to promote osteogenesis |
| WO2006110582A1 (en) | 2005-04-08 | 2006-10-19 | Xcyte Therapies, Inc. | Compositions and methods for the treatment of burns and sepsis |
| PT1926813T (pt) | 2005-09-23 | 2016-09-06 | Consejo Superior Investigacion | Populações de células que têm atividade imunorreguladora, método para isolamento e usos |
| EP1795588A1 (en) | 2005-12-07 | 2007-06-13 | Cellerix, S.L. | Use of adipose tissue derived mesenchymal stem cells for the treatment of graft versus host disease |
| WO2008036374A2 (en) | 2006-09-21 | 2008-03-27 | Medistem Laboratories, Inc. | Allogeneic stem cell transplants in non-conditioned recipients |
| EP2191835A4 (en) | 2007-09-07 | 2011-12-14 | Japan Chem Res | THERAPEUTIC AND PROPHYLACTIC AGENTS FOR ARTHRITIS |
| EP2591789B2 (en) | 2007-09-19 | 2022-07-20 | Pluristem Ltd. | Adherent cells from adipose or placenta tissues and use thereof in therapy |
| JP5539886B2 (ja) | 2007-10-17 | 2014-07-02 | ティクセル | Ｔｒ１細胞、間葉系幹細胞およびその使用 |
| GB0814249D0 (en) | 2008-08-04 | 2008-09-10 | Cellerix Sa | Uses of mesenchymal stem cells |
| ES2345867B1 (es) | 2009-04-03 | 2011-07-28 | Fundacion Instituto Mediterraneo Para La Biotecnologia Y La Investigacion Sanitaria (Imabis) | Celulas madre multipotentes derivadas de estroma de mesenterio. |
| JP5647230B2 (ja) | 2009-04-28 | 2014-12-24 | アントロジェン カンパニー リミテッドＡｎｔｅｒｏｇｅｎ Ｃｏ．， Ｌｔｄ． | 瘻孔治療のための自家及び同種異系の脂肪由来間質幹細胞組成物 |
| US8679834B2 (en) | 2009-07-09 | 2014-03-25 | TiGenix S.A.U | Methods and compositions for use in cellular therapies |
| US20140154274A1 (en) | 2011-01-12 | 2014-06-05 | Tigenix Nv | Methods and compositions for use in intralymphatic cellular therapies |
| KR20140016933A (ko) | 2011-03-11 | 2014-02-10 | 타이제닉스, 에스.에이.유. | 면역조절 활성을 갖는 세포군, 분리방법 및 용도들 |
| US20140134140A1 (en) | 2012-11-09 | 2014-05-15 | Case Western Reserve University | Mesenchymal stem cell compositions for the treatment of microbial infections |
| EP3581932A1 (en) | 2013-03-15 | 2019-12-18 | TiGenix, S.A.U. | Lymphocyte biomarkers for determining the clinical response to cell therapy |
| US20160120910A1 (en) | 2013-06-25 | 2016-05-05 | Tigenix S.A.U. | Cell populations having immunoregulatory activity, methods for the preparation and uses thereof |
| GB201604304D0 (en) | 2016-03-14 | 2016-04-27 | Tigenix S A U | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
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