JP2008540594A5 - - Google Patents

Download PDF

Info

Publication number
JP2008540594A5
JP2008540594A5 JP2008511621A JP2008511621A JP2008540594A5 JP 2008540594 A5 JP2008540594 A5 JP 2008540594A5 JP 2008511621 A JP2008511621 A JP 2008511621A JP 2008511621 A JP2008511621 A JP 2008511621A JP 2008540594 A5 JP2008540594 A5 JP 2008540594A5
Authority
JP
Japan
Prior art keywords
pain
treatment
research
effective
field
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2008511621A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008540594A (ja
JP5376942B2 (ja
Filing date
Publication date
Priority claimed from DE102005044814A external-priority patent/DE102005044814A1/de
Application filed filed Critical
Publication of JP2008540594A publication Critical patent/JP2008540594A/ja
Publication of JP2008540594A5 publication Critical patent/JP2008540594A5/ja
Application granted granted Critical
Publication of JP5376942B2 publication Critical patent/JP5376942B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2008511621A 2005-05-19 2006-05-17 置換されたスピロ化合物及び医薬の製造へのその使用 Expired - Fee Related JP5376942B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE102005023779 2005-05-19
DE102005023779.7 2005-05-19
DE102005044814.3 2005-09-20
DE102005044814A DE102005044814A1 (de) 2005-05-19 2005-09-20 Substituierte Sprio-Verbindungen und deren Verwendung zur Herstellung von Arzneimitteln
PCT/EP2006/004653 WO2006136245A1 (de) 2005-05-19 2006-05-17 Substituierte spiro-verbindungen und deren verwendung zur herstellung von arzneimitteln

Publications (3)

Publication Number Publication Date
JP2008540594A JP2008540594A (ja) 2008-11-20
JP2008540594A5 true JP2008540594A5 (enExample) 2012-06-14
JP5376942B2 JP5376942B2 (ja) 2013-12-25

Family

ID=36917274

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008511621A Expired - Fee Related JP5376942B2 (ja) 2005-05-19 2006-05-17 置換されたスピロ化合物及び医薬の製造へのその使用

Country Status (6)

Country Link
US (1) US7981883B2 (enExample)
EP (1) EP1888542A1 (enExample)
JP (1) JP5376942B2 (enExample)
CA (1) CA2608319C (enExample)
DE (1) DE102005044814A1 (enExample)
WO (1) WO2006136245A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110166124A1 (en) * 2008-07-23 2011-07-07 Mccormick Kevin D Tricyclic spirocycle derivatives and methods of use
US8232409B2 (en) 2008-10-15 2012-07-31 Janssen Pharmaceutica N.V. Heterocyclic benzimidazoles as TRPM8 modulators
US8349852B2 (en) 2009-01-13 2013-01-08 Novartis Ag Quinazolinone derivatives useful as vanilloid antagonists
CA2749856A1 (en) * 2009-02-04 2010-08-12 N.V. Organon Isoxazole-3-carboxamide derivatives
CN102762572A (zh) 2010-02-01 2012-10-31 诺瓦提斯公司 作为CRF-1受体拮抗剂的吡唑并[5,1b]*唑衍生物
WO2011092293A2 (en) 2010-02-01 2011-08-04 Novartis Ag Cyclohexyl amide derivatives as crf receptor antagonists
US8835444B2 (en) 2010-02-02 2014-09-16 Novartis Ag Cyclohexyl amide derivatives as CRF receptor antagonists
LT3786160T (lt) * 2017-10-27 2022-09-26 Boehringer Ingelheim International Gmbh Piridino dariniai ir jų terapinis panaudojimas kaip trpc6 inhibitorių

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997033887A1 (en) * 1996-03-15 1997-09-18 Du Pont Pharmaceuticals Company Spirocycle integrin inhibitors
AU6780398A (en) * 1997-03-28 1998-10-22 Du Pont Merck Pharmaceutical Company, The Heterocyclic integrin inhibitor prodrugs
JP2003505388A (ja) * 1999-07-21 2003-02-12 アストラゼネカ・アクチエボラーグ 新規化合物
DE10130020A1 (de) * 2001-06-25 2003-12-04 Gruenenthal Gmbh Substituierte 1-Oxa-2,8-diaza-spiro[4.5]dec-2-en-derivate
ATE533743T1 (de) * 2002-05-17 2011-12-15 Janssen Pharmaceutica Nv Harnstoffderivate von aminotetralin als modulatoren des vanilloid-rezeptors vr1
EP1542692B1 (en) * 2002-05-22 2011-01-05 Amgen Inc. Aminopyrimidine derivatives for use as vanilloid receptor ligands for the treatment of pain
US7125870B2 (en) * 2002-11-06 2006-10-24 Bristol-Myers Squibb Company Isoxazoline derivatives as inhibitors of matrix metalloproteinases and/or TNF-α converting enzyme
RU2387646C2 (ru) * 2003-08-29 2010-04-27 Рэнбакси Лабораториз Лимитед Ингибиторы фосфодиэстеразы типа-iv
US7786141B2 (en) * 2004-08-19 2010-08-31 Vertex Pharmaceuticals Incorporated Dihydrospiroindene modulators of muscarinic receptors
WO2007103719A2 (en) * 2006-03-03 2007-09-13 Incyte Corporation MODULATORS OF 11-β HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME

Similar Documents

Publication Publication Date Title
WO2008083097A3 (en) Steerable ablation device
JP2009526751A5 (enExample)
CA2683786C (en) Use of tapentadol in the treatment of pain and with a reduced incidence of tapentadol-induced side-effects
WO2007002927A3 (en) Imaging geometry
EP3150204A3 (en) Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral or non-oral antidiabetic drug
EP2103290A3 (en) Vacuum Wound Therapy Wound Dressing with Variable Performance Zones
JP2009517473A5 (enExample)
JP2007014793A5 (enExample)
EP2308885A3 (en) Novel compounds and methods for therapy
JP2011511805A5 (enExample)
WO2008027449A3 (en) Methods, compositions and apparatuses to treat wounds with pressures altered from atmospheric
WO2009051706A3 (en) Peptide compounds for treating obesity and insulin resistance
NO20054861L (no) Antisens oligonukleotider (ODN) mot SMAD7 og anvendelser derav i det medisinske omradet
EP3276004A3 (en) Methods for treating chronic kidney disease
JP2007515393A5 (enExample)
WO2008130037A1 (ja) マッサージ装置
EP2116274A3 (en) Obstructive sleep apnea treatment devices, systems and methods
JP2008540594A5 (enExample)
IL184037A0 (en) Combination therapy with glatiramer acetate and rasagiline for the treatment of multiple sclerosis
MA29489B1 (fr) Utilisation de tfpi dans le traitement d'infections bacteriennes aigues
EA201300421A1 (ru) Комбинированная терапия для лечения инфекции hcv
NO20075153L (no) Terapeutisk anvendelse av nefopam og analoger derav
WO2006087717A3 (en) Non-immediate effects of therapy
WO2008016640A3 (en) Use of poloxamer for the prevention and/or treatment of heart failure
JP2008545703A5 (enExample)