JP2008540573A - 4−ビアリーリル−1−フェニラゼチジン−2−オン類 - Google Patents
4−ビアリーリル−1−フェニラゼチジン−2−オン類 Download PDFInfo
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- JP2008540573A JP2008540573A JP2008511448A JP2008511448A JP2008540573A JP 2008540573 A JP2008540573 A JP 2008540573A JP 2008511448 A JP2008511448 A JP 2008511448A JP 2008511448 A JP2008511448 A JP 2008511448A JP 2008540573 A JP2008540573 A JP 2008540573A
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- Prior art keywords
- group
- lower alkyl
- fluorophenyl
- hydroxypropyl
- phenyl
- Prior art date
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- 0 C1***=SC1 Chemical compound C1***=SC1 0.000 description 6
- LFGKPUCTYYCRJF-WTFPZYKNSA-N C/C=C(\C=C(/C=C)\C#N)/c1ccc([C@H]([C@@H](CC[C@@H](c(cc2)ccc2F)O)C2=O)N2c(cc2)ccc2F)cc1 Chemical compound C/C=C(\C=C(/C=C)\C#N)/c1ccc([C@H]([C@@H](CC[C@@H](c(cc2)ccc2F)O)C2=O)N2c(cc2)ccc2F)cc1 LFGKPUCTYYCRJF-WTFPZYKNSA-N 0.000 description 1
- MAAGPEHGZKDYQJ-UKFGPCBMSA-N CC1OC1Oc1cc(Br)ccc1[C@H](C(C)(CCC(c(cc1)ccc1F)O[Si](C)(C)C(C)(C)C)C1=O)N1c1ccccc1 Chemical compound CC1OC1Oc1cc(Br)ccc1[C@H](C(C)(CCC(c(cc1)ccc1F)O[Si](C)(C)C(C)(C)C)C1=O)N1c1ccccc1 MAAGPEHGZKDYQJ-UKFGPCBMSA-N 0.000 description 1
- JNBUOIVIUDKUKB-FHKSGDNWSA-N C[C@@H]([C@@H]1O)N[C@H](CO)[C@H]2O[C@@]12O Chemical compound C[C@@H]([C@@H]1O)N[C@H](CO)[C@H]2O[C@@]12O JNBUOIVIUDKUKB-FHKSGDNWSA-N 0.000 description 1
- IPRFMZNOGZWMGY-TUYDOOLMSA-N OC(CC[C@H]([C@@H](c(ccc(-c1cc(O)ccc1)c1)c1O)N1c2ccccc2)C1=O)c(cc1)ccc1F Chemical compound OC(CC[C@H]([C@@H](c(ccc(-c1cc(O)ccc1)c1)c1O)N1c2ccccc2)C1=O)c(cc1)ccc1F IPRFMZNOGZWMGY-TUYDOOLMSA-N 0.000 description 1
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- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68123205P | 2005-05-13 | 2005-05-13 | |
US69598805P | 2005-07-01 | 2005-07-01 | |
PCT/US2006/018616 WO2006124713A2 (en) | 2005-05-13 | 2006-05-15 | 4-biarylyl-1-phenylazetidin-2-ones |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2008540573A true JP2008540573A (ja) | 2008-11-20 |
Family
ID=37431955
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008511448A Pending JP2008540573A (ja) | 2005-05-13 | 2006-05-15 | 4−ビアリーリル−1−フェニラゼチジン−2−オン類 |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1885694A2 (de) |
JP (1) | JP2008540573A (de) |
TW (1) | TW200740752A (de) |
WO (1) | WO2006124713A2 (de) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10983108B2 (en) | 2017-03-31 | 2021-04-20 | Quest Diagnostics Investments Llc | Methods for quantitation of insulin and C-peptide |
US11486874B2 (en) | 2015-03-03 | 2022-11-01 | Quest Diagnostics Investments Llc | Methods for quantitation of insulin levels by mass spectrometry |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060287254A1 (en) * | 2001-01-26 | 2006-12-21 | Schering Corporation | Use of substituted azetidinone compounds for the treatment of sitosterolemia |
US7871998B2 (en) | 2003-12-23 | 2011-01-18 | Astrazeneca Ab | Diphenylazetidinone derivatives possessing cholesterol absorption inhibitory activity |
UY29607A1 (es) | 2005-06-20 | 2007-01-31 | Astrazeneca Ab | Compuestos quimicos |
AR057072A1 (es) | 2005-06-22 | 2007-11-14 | Astrazeneca Ab | Compuestos quimicos derivados de 2-azetidinona, formulacion farmaceutica y un proceso de preparacion del compuesto |
SA06270191B1 (ar) | 2005-06-22 | 2010-03-29 | استرازينيكا ايه بي | مشتقات من 2- أزيتيدينون جديدة باعتبارها مثبطات لامتصاص الكوليسترول لعلاج حالات فرط نسبة الدهون في الدم |
AR060623A1 (es) | 2006-04-27 | 2008-07-02 | Astrazeneca Ab | Compuestos derivados de 2-azetidinona y un metodo de preparacion |
JO3598B1 (ar) | 2006-10-10 | 2020-07-05 | Infinity Discovery Inc | الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني |
WO2008061238A2 (en) * | 2006-11-16 | 2008-05-22 | Ironwood Pharmaceuticals, Inc. | Processes for production of 4-biphenylyazetidin-2-ones |
JPWO2008108486A1 (ja) | 2007-03-06 | 2010-06-17 | 帝人ファーマ株式会社 | 1−ビアリールアゼチジノン誘導体 |
AR065850A1 (es) * | 2007-03-28 | 2009-07-08 | Takeda Pharmaceutical | Composicion farmaceutica solida que comprende un derivado de benzimidazol-7-carboxilato y un agente de control de ph |
TW201000107A (en) | 2008-04-09 | 2010-01-01 | Infinity Pharmaceuticals Inc | Inhibitors of fatty acid amide hydrolase |
CA2732018C (en) | 2008-07-31 | 2017-07-04 | Takeda Pharmaceutical Company Limited | Solid pharmaceutical composition |
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WO2010118155A1 (en) | 2009-04-07 | 2010-10-14 | Infinity Pharmaceuticals, Inc. | Inhibitors of fatty acid amide hydrolase |
CN102834401B (zh) | 2010-02-03 | 2016-08-24 | 无限药品股份有限公司 | 脂肪酸酰胺水解酶抑制剂 |
EP2575821B1 (de) | 2010-05-26 | 2015-08-12 | Satiogen Pharmaceuticals, Inc. | Gallensäurerückflusshemmer und satiogene zur behandlung von diabetes, adipositas und entzündlichen magen-darm-erkrankungen |
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EA029581B1 (ru) | 2011-10-28 | 2018-04-30 | ЛУМЕНА ФАРМАСЬЮТИКАЛС ЭлЭлСи | Применение ингибиторов рециркуляции желчных кислот для лечения холестатического заболевания печени или прурита |
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EP1660446A2 (de) * | 2003-08-28 | 2006-05-31 | Microbia, Inc. | Angebundene dimere und trimere von 1,4-diphenylazetidin-2-onen |
EP1682499B1 (de) * | 2003-11-10 | 2007-08-08 | Microbia, Inc. | 4-biarylyl-1-phenylazetidin-2-one |
-
2006
- 2006-05-15 TW TW095117088A patent/TW200740752A/zh unknown
- 2006-05-15 WO PCT/US2006/018616 patent/WO2006124713A2/en active Application Filing
- 2006-05-15 EP EP06759778A patent/EP1885694A2/de not_active Withdrawn
- 2006-05-15 JP JP2008511448A patent/JP2008540573A/ja active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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US11486874B2 (en) | 2015-03-03 | 2022-11-01 | Quest Diagnostics Investments Llc | Methods for quantitation of insulin levels by mass spectrometry |
US10983108B2 (en) | 2017-03-31 | 2021-04-20 | Quest Diagnostics Investments Llc | Methods for quantitation of insulin and C-peptide |
Also Published As
Publication number | Publication date |
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TW200740752A (en) | 2007-11-01 |
WO2006124713A2 (en) | 2006-11-23 |
EP1885694A2 (de) | 2008-02-13 |
WO2006124713A3 (en) | 2007-01-18 |
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