JP2008539240A5 - - Google Patents
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- Publication number
- JP2008539240A5 JP2008539240A5 JP2008508975A JP2008508975A JP2008539240A5 JP 2008539240 A5 JP2008539240 A5 JP 2008539240A5 JP 2008508975 A JP2008508975 A JP 2008508975A JP 2008508975 A JP2008508975 A JP 2008508975A JP 2008539240 A5 JP2008539240 A5 JP 2008539240A5
- Authority
- JP
- Japan
- Prior art keywords
- granules
- formulation
- sustained release
- mesh
- wax
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000009472 formulation Methods 0.000 claims 23
- 239000000203 mixture Substances 0.000 claims 23
- 239000008187 granular material Substances 0.000 claims 21
- 238000013268 sustained release Methods 0.000 claims 20
- 239000012730 sustained-release form Substances 0.000 claims 20
- 239000000463 material Substances 0.000 claims 11
- 238000000034 method Methods 0.000 claims 11
- 239000001993 wax Substances 0.000 claims 11
- 239000004480 active ingredient Substances 0.000 claims 10
- FFGPTBGBLSHEPO-UHFFFAOYSA-N carbamazepine Chemical compound C1=CC2=CC=CC=C2N(C(=O)N)C2=CC=CC=C21 FFGPTBGBLSHEPO-UHFFFAOYSA-N 0.000 claims 7
- 229960000623 carbamazepine Drugs 0.000 claims 7
- 230000000717 retained effect Effects 0.000 claims 6
- 238000005029 sieve analysis Methods 0.000 claims 4
- 238000000338 in vitro Methods 0.000 claims 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 3
- 239000000654 additive Substances 0.000 claims 2
- CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 claims 2
- 238000002844 melting Methods 0.000 claims 2
- 230000008018 melting Effects 0.000 claims 2
- VEPOHXYIFQMVHW-PVJVQHJQSA-N (2r,3r)-2,3-dihydroxybutanedioic acid;(2s,3s)-3,4-dimethyl-2-phenylmorpholine Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O.O1CCN(C)[C@@H](C)[C@@H]1C1=CC=CC=C1 VEPOHXYIFQMVHW-PVJVQHJQSA-N 0.000 claims 1
- 235000013871 bee wax Nutrition 0.000 claims 1
- 239000012166 beeswax Substances 0.000 claims 1
- 239000011230 binding agent Substances 0.000 claims 1
- 235000013869 carnauba wax Nutrition 0.000 claims 1
- 239000004203 carnauba wax Substances 0.000 claims 1
- CGDDQFMPGMYYQP-UHFFFAOYSA-N disopyramide phosphate Chemical compound OP(O)(O)=O.C=1C=CC=NC=1C(C(N)=O)(CCN(C(C)C)C(C)C)C1=CC=CC=C1 CGDDQFMPGMYYQP-UHFFFAOYSA-N 0.000 claims 1
- 229960001863 disopyramide phosphate Drugs 0.000 claims 1
- 238000004090 dissolution Methods 0.000 claims 1
- 239000012738 dissolution medium Substances 0.000 claims 1
- 238000013265 extended release Methods 0.000 claims 1
- 239000000945 filler Substances 0.000 claims 1
- 229960000905 indomethacin Drugs 0.000 claims 1
- DKYWVDODHFEZIM-UHFFFAOYSA-N ketoprofen Chemical compound OC(=O)C(C)C1=CC=CC(C(=O)C=2C=CC=CC=2)=C1 DKYWVDODHFEZIM-UHFFFAOYSA-N 0.000 claims 1
- 229960000991 ketoprofen Drugs 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 229960003725 phendimetrazine tartrate Drugs 0.000 claims 1
- 230000036470 plasma concentration Effects 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 239000000080 wetting agent Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67444405P | 2005-04-25 | 2005-04-25 | |
| PCT/US2006/015373 WO2006116247A1 (en) | 2005-04-25 | 2006-04-25 | Extended release formulations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008539240A JP2008539240A (ja) | 2008-11-13 |
| JP2008539240A5 true JP2008539240A5 (https=) | 2009-05-21 |
Family
ID=36698750
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008508975A Withdrawn JP2008539240A (ja) | 2005-04-25 | 2006-04-25 | 持続放出性処方物 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20060275367A1 (https=) |
| EP (1) | EP1877040A1 (https=) |
| JP (1) | JP2008539240A (https=) |
| AU (1) | AU2006239838A1 (https=) |
| BR (1) | BRPI0610257A2 (https=) |
| CA (1) | CA2605792A1 (https=) |
| MX (1) | MX2007013327A (https=) |
| RU (1) | RU2007143556A (https=) |
| WO (1) | WO2006116247A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007122636A1 (en) * | 2006-04-25 | 2007-11-01 | Panacea Biotec Ltd | Pharmaceutical compositions containing long chain fatty acids as excipients as well as a process for manufacturing the same |
| AU2014201170B2 (en) * | 2006-12-20 | 2015-09-24 | Mylan Pharmaceuticals Ulc | Pharmaceutical composition comprising a hot-melt granulated lubricant |
| AU2007335156A1 (en) * | 2006-12-20 | 2008-06-26 | Mylan Pharmaceuticals Ulc | Pharmaceutical composition comprising a hot-melt granulated lubricant |
| EP1972336A1 (en) * | 2007-03-19 | 2008-09-24 | LEK Pharmaceuticals D.D. | Hot-melt micropellets |
| CN102036656A (zh) * | 2008-03-21 | 2011-04-27 | 米兰制药有限公司 | 含有蜡的缓释制剂 |
| EP2872121B1 (en) | 2012-07-12 | 2018-09-05 | SpecGx LLC | Extended release, abuse deterrent pharmaceutical compositions |
| WO2014051443A1 (en) * | 2012-09-27 | 2014-04-03 | Mendoza Wendell G | Method for producing extended-release potassium citrate wax matrix tablet |
| US10369108B2 (en) * | 2013-03-15 | 2019-08-06 | Mylan Laboratories, Inc. | Hot melt granulation formulations of poorly water-soluble active agents |
| WO2022266311A1 (en) * | 2021-06-16 | 2022-12-22 | Summit Biomedical Imaging | PARPi-FL FORMULATIONS |
| CN117100711A (zh) * | 2022-05-16 | 2023-11-24 | 江苏万珺医药科技有限公司 | 一种含有盐酸曲唑酮的缓释片剂及其制备方法 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2489439A (en) * | 1947-06-27 | 1949-11-29 | Samuel M Taylor | Record controlled printing machine |
| US4443428A (en) * | 1982-06-21 | 1984-04-17 | Euroceltique, S.A. | Extended action controlled release compositions |
| USRE34990E (en) * | 1986-08-07 | 1995-07-04 | Ciba-Geigy Corporation | Oral therapeutic system having systemic action |
| CH668187A5 (de) * | 1986-08-07 | 1988-12-15 | Ciba Geigy Ag | Therapeutisches system mit systemischer wirkung. |
| FI894611L (fi) * | 1988-09-30 | 1990-03-31 | May & Baker Ltd | Granulaera farmaceutiska preparat. |
| US5169645A (en) * | 1989-10-31 | 1992-12-08 | Duquesne University Of The Holy Ghost | Directly compressible granules having improved flow properties |
| TW209174B (https=) * | 1991-04-19 | 1993-07-11 | Takeda Pharm Industry Co Ltd | |
| US5326570A (en) * | 1991-07-23 | 1994-07-05 | Pharmavene, Inc. | Advanced drug delivery system and method of treating psychiatric, neurological and other disorders with carbamazepine |
| JP2616252B2 (ja) * | 1992-10-16 | 1997-06-04 | 日本新薬株式会社 | ワックスマトリックスの製法 |
| KR100354702B1 (ko) * | 1993-11-23 | 2002-12-28 | 유로-셀티크 소시에떼 아노뉨 | 약학조성물의제조방법및서방형조성물 |
| DE4423078B4 (de) * | 1994-07-01 | 2005-01-13 | Awd.Pharma Gmbh & Co. Kg | Verfahren zur Herstellung einer Carbamazepin-Arzneiform mit verzögerter Wirkstofffreisetzung |
| US5980942A (en) * | 1997-01-23 | 1999-11-09 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Zero-order sustained release matrix tablet formulations of carbamazepine |
| US6296873B1 (en) * | 1997-01-23 | 2001-10-02 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Zero-order sustained release delivery system for carbamazephine derivatives |
| DE19729487A1 (de) * | 1997-07-10 | 1999-01-14 | Dresden Arzneimittel | Verfahren zur Herstellung von Wirkstoff-Zubereitungen mit kontrollierter Freisetzung aus einer Matrix |
| DE19747261A1 (de) * | 1997-10-25 | 1999-04-29 | Bayer Ag | Osmotisches Arzneimittelfreisetzungssystem |
| IL125244A (en) * | 1998-07-07 | 2002-12-01 | Yissum Res Dev Co | Pharmaceutical compositions containing low-melting waxes |
| US6378526B1 (en) * | 1998-08-03 | 2002-04-30 | Insite Vision, Incorporated | Methods of ophthalmic administration |
| US6162466A (en) * | 1999-04-15 | 2000-12-19 | Taro Pharmaceutical Industries Ltd. | Sustained release formulation of carbamazepine |
| US20020015730A1 (en) * | 2000-03-09 | 2002-02-07 | Torsten Hoffmann | Pharmaceutical formulations and method for making |
| ITMI20012749A1 (it) * | 2001-12-21 | 2003-06-21 | Chiesi Farma Spa | Procedimento per la preparazione mediante trattamento con microonde di composti di inclusione tra farmaco e ciclodestrine e prodotti ottenut |
| US6572889B1 (en) * | 2002-03-07 | 2003-06-03 | Noveon Ip Holdings Corp. | Controlled release solid dosage carbamazepine formulations |
| NZ542303A (en) * | 2003-03-14 | 2008-12-24 | Nirmal Mulye | A process for preparing sustained release tablets |
| US20040241234A1 (en) * | 2003-06-02 | 2004-12-02 | Alpharma, Inc. | Controlled release press-coated formulations of water-soluble active agents |
| WO2005079752A2 (en) * | 2004-02-11 | 2005-09-01 | Rubicon Research Private Limited | Controlled release pharmaceutical compositions with improved bioavailability |
| US20080075785A1 (en) * | 2006-09-22 | 2008-03-27 | San-Laung Chow | Controlled release hydrogel formulation |
-
2006
- 2006-04-25 JP JP2008508975A patent/JP2008539240A/ja not_active Withdrawn
- 2006-04-25 WO PCT/US2006/015373 patent/WO2006116247A1/en not_active Ceased
- 2006-04-25 US US11/410,502 patent/US20060275367A1/en not_active Abandoned
- 2006-04-25 MX MX2007013327A patent/MX2007013327A/es unknown
- 2006-04-25 EP EP06751176A patent/EP1877040A1/en not_active Withdrawn
- 2006-04-25 BR BRPI0610257-3A patent/BRPI0610257A2/pt not_active IP Right Cessation
- 2006-04-25 AU AU2006239838A patent/AU2006239838A1/en not_active Abandoned
- 2006-04-25 CA CA002605792A patent/CA2605792A1/en not_active Abandoned
- 2006-04-25 RU RU2007143556/15A patent/RU2007143556A/ru not_active Application Discontinuation
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