JP2008536098A5 - - Google Patents
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- Publication number
- JP2008536098A5 JP2008536098A5 JP2007556224A JP2007556224A JP2008536098A5 JP 2008536098 A5 JP2008536098 A5 JP 2008536098A5 JP 2007556224 A JP2007556224 A JP 2007556224A JP 2007556224 A JP2007556224 A JP 2007556224A JP 2008536098 A5 JP2008536098 A5 JP 2008536098A5
- Authority
- JP
- Japan
- Prior art keywords
- adamts
- cancer
- antibody
- level
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000051352 ADAMTS7 Human genes 0.000 claims 19
- 108091005667 ADAMTS7 Proteins 0.000 claims 19
- 238000000034 method Methods 0.000 claims 16
- 239000000523 sample Substances 0.000 claims 8
- 210000002700 urine Anatomy 0.000 claims 6
- 206010028980 Neoplasm Diseases 0.000 claims 4
- 239000012472 biological sample Substances 0.000 claims 4
- 201000011510 cancer Diseases 0.000 claims 4
- 239000013068 control sample Substances 0.000 claims 4
- 206010036790 Productive cough Diseases 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 2
- 239000013592 cell lysate Substances 0.000 claims 2
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims 2
- 238000003745 diagnosis Methods 0.000 claims 2
- 239000012530 fluid Substances 0.000 claims 2
- 210000002445 nipple Anatomy 0.000 claims 2
- 210000002966 serum Anatomy 0.000 claims 2
- 210000003802 sputum Anatomy 0.000 claims 2
- 208000024794 sputum Diseases 0.000 claims 2
- 210000001519 tissue Anatomy 0.000 claims 2
- 208000005440 Basal Cell Neoplasms Diseases 0.000 claims 1
- 206010004146 Basal cell carcinoma Diseases 0.000 claims 1
- 206010005003 Bladder cancer Diseases 0.000 claims 1
- 208000003174 Brain Neoplasms Diseases 0.000 claims 1
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 201000009030 Carcinoma Diseases 0.000 claims 1
- 206010008342 Cervix carcinoma Diseases 0.000 claims 1
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 208000000461 Esophageal Neoplasms Diseases 0.000 claims 1
- 206010017993 Gastrointestinal neoplasms Diseases 0.000 claims 1
- 206010062038 Lip neoplasm Diseases 0.000 claims 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 1
- 208000003445 Mouth Neoplasms Diseases 0.000 claims 1
- 206010030155 Oesophageal carcinoma Diseases 0.000 claims 1
- 206010033128 Ovarian cancer Diseases 0.000 claims 1
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
- 208000006265 Renal cell carcinoma Diseases 0.000 claims 1
- 208000000453 Skin Neoplasms Diseases 0.000 claims 1
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 1
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 claims 1
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 claims 1
- 208000009956 adenocarcinoma Diseases 0.000 claims 1
- 201000010881 cervical cancer Diseases 0.000 claims 1
- 208000029742 colonic neoplasm Diseases 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 210000000981 epithelium Anatomy 0.000 claims 1
- 201000004101 esophageal cancer Diseases 0.000 claims 1
- 239000007850 fluorescent dye Substances 0.000 claims 1
- 206010017758 gastric cancer Diseases 0.000 claims 1
- 208000012987 lip and oral cavity carcinoma Diseases 0.000 claims 1
- 201000006721 lip cancer Diseases 0.000 claims 1
- 201000007270 liver cancer Diseases 0.000 claims 1
- 208000014018 liver neoplasm Diseases 0.000 claims 1
- 201000005202 lung cancer Diseases 0.000 claims 1
- 208000020816 lung neoplasm Diseases 0.000 claims 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 1
- 201000002528 pancreatic cancer Diseases 0.000 claims 1
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 1
- 230000002285 radioactive effect Effects 0.000 claims 1
- 201000000849 skin cancer Diseases 0.000 claims 1
- 201000002314 small intestine cancer Diseases 0.000 claims 1
- 239000007790 solid phase Substances 0.000 claims 1
- 201000011549 stomach cancer Diseases 0.000 claims 1
- 201000005112 urinary bladder cancer Diseases 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65381805P | 2005-02-17 | 2005-02-17 | |
| PCT/US2006/004985 WO2006091412A2 (en) | 2005-02-17 | 2006-02-13 | Adamts-7 as a biomarker for cancers of epithelial origin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008536098A JP2008536098A (ja) | 2008-09-04 |
| JP2008536098A5 true JP2008536098A5 (https=) | 2009-04-30 |
Family
ID=36927896
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007556224A Pending JP2008536098A (ja) | 2005-02-17 | 2006-02-13 | 上皮由来の癌のためのバイオマーカーとしてのａｄａｍｔｓ−７ |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20080268473A1 (https=) |
| EP (1) | EP1848739A4 (https=) |
| JP (1) | JP2008536098A (https=) |
| CN (1) | CN101120016A (https=) |
| AU (1) | AU2006216925A1 (https=) |
| CA (1) | CA2598004A1 (https=) |
| WO (1) | WO2006091412A2 (https=) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0307403D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Selection by compartmentalised screening |
| GB0307428D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Compartmentalised combinatorial chemistry |
| US20060078893A1 (en) | 2004-10-12 | 2006-04-13 | Medical Research Council | Compartmentalised combinatorial chemistry by microfluidic control |
| US20050221339A1 (en) | 2004-03-31 | 2005-10-06 | Medical Research Council Harvard University | Compartmentalised screening by microfluidic control |
| US7968287B2 (en) | 2004-10-08 | 2011-06-28 | Medical Research Council Harvard University | In vitro evolution in microfluidic systems |
| JP2009536313A (ja) | 2006-01-11 | 2009-10-08 | レインダンス テクノロジーズ， インコーポレイテッド | ナノリアクターの形成および制御において使用するマイクロ流体デバイスおよび方法 |
| US9562837B2 (en) | 2006-05-11 | 2017-02-07 | Raindance Technologies, Inc. | Systems for handling microfludic droplets |
| ATE540750T1 (de) | 2006-05-11 | 2012-01-15 | Raindance Technologies Inc | Mikrofluidische vorrichtung und verfahren |
| EP3536396B1 (en) | 2006-08-07 | 2022-03-30 | The President and Fellows of Harvard College | Fluorocarbon emulsion stabilizing surfactants |
| US8772046B2 (en) | 2007-02-06 | 2014-07-08 | Brandeis University | Manipulation of fluids and reactions in microfluidic systems |
| US8592221B2 (en) | 2007-04-19 | 2013-11-26 | Brandeis University | Manipulation of fluids, fluid components and reactions in microfluidic systems |
| US12038438B2 (en) | 2008-07-18 | 2024-07-16 | Bio-Rad Laboratories, Inc. | Enzyme quantification |
| EP2315629B1 (en) | 2008-07-18 | 2021-12-15 | Bio-Rad Laboratories, Inc. | Droplet libraries |
| EP3415235B1 (en) | 2009-03-23 | 2025-11-12 | Bio-Rad Laboratories, Inc. | Manipulation of microfluidic droplets |
| WO2011042564A1 (en) | 2009-10-09 | 2011-04-14 | Universite De Strasbourg | Labelled silica-based nanomaterial with enhanced properties and uses thereof |
| EP2517025B1 (en) | 2009-12-23 | 2019-11-27 | Bio-Rad Laboratories, Inc. | Methods for reducing the exchange of molecules between droplets |
| US9399797B2 (en) | 2010-02-12 | 2016-07-26 | Raindance Technologies, Inc. | Digital analyte analysis |
| CA2789425C (en) | 2010-02-12 | 2020-04-28 | Raindance Technologies, Inc. | Digital analyte analysis with polymerase error correction |
| US10351905B2 (en) | 2010-02-12 | 2019-07-16 | Bio-Rad Laboratories, Inc. | Digital analyte analysis |
| US9366632B2 (en) | 2010-02-12 | 2016-06-14 | Raindance Technologies, Inc. | Digital analyte analysis |
| CA2796217A1 (en) * | 2010-04-13 | 2011-10-20 | The Trustees Of Columbia University In The City Of New York | Biomarkers based on a multi-cancer invasion-associated mechanism |
| WO2012045012A2 (en) | 2010-09-30 | 2012-04-05 | Raindance Technologies, Inc. | Sandwich assays in droplets |
| EP3859011A1 (en) | 2011-02-11 | 2021-08-04 | Bio-Rad Laboratories, Inc. | Methods for forming mixed droplets |
| EP3736281A1 (en) | 2011-02-18 | 2020-11-11 | Bio-Rad Laboratories, Inc. | Compositions and methods for molecular labeling |
| US8841071B2 (en) | 2011-06-02 | 2014-09-23 | Raindance Technologies, Inc. | Sample multiplexing |
| EP3709018A1 (en) | 2011-06-02 | 2020-09-16 | Bio-Rad Laboratories, Inc. | Microfluidic apparatus for identifying components of a chemical reaction |
| US8658430B2 (en) | 2011-07-20 | 2014-02-25 | Raindance Technologies, Inc. | Manipulating droplet size |
| EP3495817B1 (en) | 2012-02-10 | 2024-10-16 | Bio-Rad Laboratories, Inc. | Molecular diagnostic screening assay |
| EP3524693A1 (en) | 2012-04-30 | 2019-08-14 | Raindance Technologies, Inc. | Digital analyte analysis |
| EP2986762B1 (en) | 2013-04-19 | 2019-11-06 | Bio-Rad Laboratories, Inc. | Digital analyte analysis |
| US11901041B2 (en) | 2013-10-04 | 2024-02-13 | Bio-Rad Laboratories, Inc. | Digital analysis of nucleic acid modification |
| US9944977B2 (en) | 2013-12-12 | 2018-04-17 | Raindance Technologies, Inc. | Distinguishing rare variations in a nucleic acid sequence from a sample |
| US11193176B2 (en) | 2013-12-31 | 2021-12-07 | Bio-Rad Laboratories, Inc. | Method for detecting and quantifying latent retroviral RNA species |
| US10647981B1 (en) | 2015-09-08 | 2020-05-12 | Bio-Rad Laboratories, Inc. | Nucleic acid library generation methods and compositions |
| CN105420366B (zh) * | 2015-12-17 | 2018-07-06 | 张军利 | Adamts-2基因及其表达产物在诊治胃癌中的应用 |
| US10998178B2 (en) | 2017-08-28 | 2021-05-04 | Purdue Research Foundation | Systems and methods for sample analysis using swabs |
| CN112553184B (zh) * | 2019-09-25 | 2021-08-03 | 北京大学 | 金属蛋白酶adamts-7的免疫原性肽段及其在抗动脉粥样硬化及相关疾病的应用 |
| EP4399324A4 (en) * | 2021-09-10 | 2025-08-27 | Broad Inst Inc | ADAMTS7 SUBSTRATES AND BIOMARKERS |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US639161A (en) * | 1899-08-07 | 1899-12-12 | Grant Mccargo | Incandescent lamp. |
| US6391610B1 (en) * | 1999-08-06 | 2002-05-21 | The Cleveland Clinic Foundation | Nucleic acids encoding zinc metalloproteases |
| US7482135B2 (en) * | 2000-05-17 | 2009-01-27 | Nederlandse Organisatie Voor Toegepast | Proteolytic enzymes in urine as diagnostic parameters in diseases involving matrix remodelling |
| US6613970B2 (en) * | 2001-08-02 | 2003-09-02 | Maurice P. Davies | Process of making acoustic devices |
| EP1639090A4 (en) * | 2003-06-09 | 2008-04-16 | Univ Michigan | COMPOSITIONS AND METHODS OF TREATMENT AND DIAGNOSIS OF CANCER |
-
2006
- 2006-02-13 CA CA002598004A patent/CA2598004A1/en not_active Abandoned
- 2006-02-13 US US11/815,821 patent/US20080268473A1/en not_active Abandoned
- 2006-02-13 AU AU2006216925A patent/AU2006216925A1/en not_active Abandoned
- 2006-02-13 WO PCT/US2006/004985 patent/WO2006091412A2/en not_active Ceased
- 2006-02-13 JP JP2007556224A patent/JP2008536098A/ja active Pending
- 2006-02-13 CN CNA2006800051666A patent/CN101120016A/zh active Pending
- 2006-02-13 EP EP06734907A patent/EP1848739A4/en not_active Withdrawn
-
2009
- 2009-09-08 US US12/555,763 patent/US20100209944A1/en not_active Abandoned
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