JP2008534568A5 - - Google Patents
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- Publication number
- JP2008534568A5 JP2008534568A5 JP2008503608A JP2008503608A JP2008534568A5 JP 2008534568 A5 JP2008534568 A5 JP 2008534568A5 JP 2008503608 A JP2008503608 A JP 2008503608A JP 2008503608 A JP2008503608 A JP 2008503608A JP 2008534568 A5 JP2008534568 A5 JP 2008534568A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- disorder
- dihydro
- alkyl
- piperazin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 C[C@](CNCC1)N1c1nc([C@](CC2)OC(*)*)c2cc1 Chemical compound C[C@](CNCC1)N1c1nc([C@](CC2)OC(*)*)c2cc1 0.000 description 8
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66718405P | 2005-03-31 | 2005-03-31 | |
| US76215906P | 2006-01-26 | 2006-01-26 | |
| PCT/IB2006/000655 WO2006103511A1 (en) | 2005-03-31 | 2006-03-21 | Cyclopentapyridine and tetrahydroquinoline derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008534568A JP2008534568A (ja) | 2008-08-28 |
| JP2008534568A5 true JP2008534568A5 (enExample) | 2008-10-09 |
| JP4318744B2 JP4318744B2 (ja) | 2009-08-26 |
Family
ID=36218589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008503608A Expired - Fee Related JP4318744B2 (ja) | 2005-03-31 | 2006-03-21 | シクロペンタピリジンおよびテトラヒドロキノリン誘導体 |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US7507732B2 (enExample) |
| EP (1) | EP1869000A1 (enExample) |
| JP (1) | JP4318744B2 (enExample) |
| KR (1) | KR100894006B1 (enExample) |
| AP (1) | AP2007004144A0 (enExample) |
| AR (1) | AR054021A1 (enExample) |
| AU (1) | AU2006228378A1 (enExample) |
| BR (1) | BRPI0609268A2 (enExample) |
| CA (1) | CA2602348C (enExample) |
| CR (1) | CR9386A (enExample) |
| DO (1) | DOP2006000076A (enExample) |
| EA (1) | EA200701853A1 (enExample) |
| GT (1) | GT200600128A (enExample) |
| IL (1) | IL185492A0 (enExample) |
| MA (1) | MA29354B1 (enExample) |
| MX (1) | MX2007012082A (enExample) |
| NL (1) | NL1031473C2 (enExample) |
| NO (1) | NO20074368L (enExample) |
| NZ (1) | NZ560917A (enExample) |
| PE (1) | PE20061333A1 (enExample) |
| TN (1) | TNSN07367A1 (enExample) |
| TW (1) | TW200722423A (enExample) |
| UY (1) | UY29446A1 (enExample) |
| WO (1) | WO2006103511A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1701943A1 (en) | 2003-12-23 | 2006-09-20 | Myogen, Inc. | 5-ht2 receptors modulators, their pharmaceutical compositions and their use for the treatment of cardiovascular and muscle diseases |
| TW200633721A (en) * | 2004-12-14 | 2006-10-01 | Shionogi & Co | A pharmaceutical composition for treating constipation |
| JP5528699B2 (ja) | 2006-05-16 | 2014-06-25 | 武田薬品工業株式会社 | 縮合複素環化合物およびその用途 |
| ATE496894T1 (de) * | 2006-07-14 | 2011-02-15 | Pfizer Prod Inc | Tartratsalz von (7s)-7-ä(5-fluor-2- |
| JP2010500300A (ja) | 2006-08-08 | 2010-01-07 | サノフィ−アベンティス | アリールアミノアリール−アルキル−置換イミダゾリジン−２，４−ジオン、それらの製造法、それらの化合物を含有する薬剤、およびそれらの使用 |
| WO2008068157A1 (en) * | 2006-12-07 | 2008-06-12 | F. Hoffmann-La Roche Ag | 2-aminoquinolines as 5-ht(5a) receptor antagonists |
| JP5520051B2 (ja) | 2007-11-15 | 2014-06-11 | 武田薬品工業株式会社 | 縮合ピリジン誘導体およびその用途 |
| CN101959864A (zh) | 2008-03-07 | 2011-01-26 | 弗·哈夫曼-拉罗切有限公司 | 2-氨基喹啉衍生物 |
| SG157299A1 (en) | 2008-05-09 | 2009-12-29 | Agency Science Tech & Res | Diagnosis and treatment of kawasaki disease |
| WO2010003624A2 (en) | 2008-07-09 | 2010-01-14 | Sanofi-Aventis | Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof |
| WO2010068601A1 (en) | 2008-12-08 | 2010-06-17 | Sanofi-Aventis | A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof |
| SG178880A1 (en) | 2009-08-26 | 2012-04-27 | Sanofi Sa | Novel crystalline heteroaromatic fluoroglycoside hydrates, pharmaceuticals comprising these compounds and their use |
| TWI558398B (zh) | 2009-09-22 | 2016-11-21 | 諾華公司 | 菸鹼乙醯膽鹼受體α７活化劑之用途 |
| WO2011071136A1 (ja) | 2009-12-11 | 2011-06-16 | アステラス製薬株式会社 | 線維筋痛症治療剤 |
| US8674218B2 (en) | 2010-12-15 | 2014-03-18 | General Electric Company | Restraint system for an energy storage device |
| EP2766349B1 (de) | 2011-03-08 | 2016-06-01 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| WO2012120054A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| WO2012120056A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| WO2012120055A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| EP2683704B1 (de) | 2011-03-08 | 2014-12-17 | Sanofi | Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| WO2015066344A1 (en) | 2013-11-01 | 2015-05-07 | Arena Pharmaceuticals, Inc. | 5-ht2c receptor agonists and compositions and methods of use |
| WO2019131902A1 (ja) | 2017-12-27 | 2019-07-04 | 武田薬品工業株式会社 | 腹圧性尿失禁および便失禁の治療薬 |
| US20210393621A1 (en) | 2018-10-26 | 2021-12-23 | The Research Foundation For The State University Of New York | Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia |
| CN110236526B (zh) * | 2019-06-28 | 2022-01-28 | 李秋 | 基于咀嚼吞咽动作及心电活动的摄食行为分析和检测方法 |
| WO2024026423A1 (en) * | 2022-07-27 | 2024-02-01 | Black Diamond Therapeutics, Inc. | Substituted quinoline derivatives as pi3k inhibitors |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01211581A (ja) | 1988-02-18 | 1989-08-24 | Meiji Seika Kaisha Ltd | シクロペンテノピリジン誘導体および抗潰瘍剤 |
| US4985352A (en) | 1988-02-29 | 1991-01-15 | The Trustees Of Columbia University In The City Of New York | DNA encoding serotonin 1C (5HT1c) receptor, isolated 5HT1c receptor, mammalian cells expressing same and uses thereof |
| EP0361489A3 (en) | 1988-09-30 | 1991-06-12 | Chugai Seiyaku Kabushiki Kaisha | Novel 3,4-diaminoquinoline and pyridine compounds |
| DK0385237T3 (da) | 1989-03-03 | 1994-07-25 | Dainippon Pharmaceutical Co | 2-(1-Piperazinyl)-4-phenylcycloalkanopyridinderivater, fremgangsmåde til fremstilling deraf og farmaceutisk præparat indeholdende dem |
| JP2660086B2 (ja) | 1990-07-03 | 1997-10-08 | 明治製菓株式会社 | 脳及び心機能障害改善剤 |
| JPH04103572A (ja) | 1990-08-20 | 1992-04-06 | Dainippon Pharmaceut Co Ltd | ４―フェニル―２―（１―ピペラジニル）ピリジン誘導体 |
| EP0572863A1 (de) | 1992-06-05 | 1993-12-08 | F. Hoffmann-La Roche Ag | ZNS Pyrazinoindole |
| DE4326151A1 (de) | 1993-08-04 | 1995-02-09 | Hoechst Ag | Aromatische Verbindungen und ihre Verwendung in flüssigkristallinen Mischungen |
| TW270114B (enExample) | 1993-10-22 | 1996-02-11 | Hoffmann La Roche | |
| TW334423B (en) | 1993-10-22 | 1998-06-21 | Hoffmann La Roche | Tricyclic 1-aminoethylpyrrole-derivatives |
| US5698766A (en) | 1995-04-05 | 1997-12-16 | The Regents Of The University Of California | Transgenic animal model for testing drugs for treating eating disorders and epilepsy |
| TW477787B (en) | 1996-08-27 | 2002-03-01 | Pfizer | Pyrido six-membered nitrogen-containing cyclic ring derivatives having corticotropin releasing factor antagonist activity and pharmaceutical composition containing same |
| AU5343298A (en) | 1997-01-13 | 1998-08-03 | Yamanouchi Pharmaceutical Co., Ltd. | 5-ht2c receptor agonists and aminoalkylindazole derivatives |
| PT863136E (pt) | 1997-02-25 | 2004-01-30 | Akzo Nobel Nv | Derivados de azetidina e de pirrolidina |
| US6322738B1 (en) | 1997-07-24 | 2001-11-27 | Husky Injection Molding Systems Ltd. | Method of injection over-molding articles |
| AU9810498A (en) | 1997-10-24 | 1999-05-17 | Neurogen Corporation | 1-(2-naphthyl) and 1-(2-azanaphthyl)-4 -(1-phenylmethyl)piperazines being dopamine d4 receptor subtyp e ligands |
| US6040448A (en) | 1997-10-24 | 2000-03-21 | Neurogen Corporation | Certain 1-(2-naphthyl) and 1-(2-azanaphthyl)-4-(1-phenylmethyl) piperazines, dopamine receptor subtype specific ligands |
| AU4037699A (en) | 1998-05-08 | 1999-11-29 | Akzo Nobel N.V. | Novel aryl-hydro naphthalenal kanamines |
| GB9819033D0 (en) | 1998-09-01 | 1998-10-28 | Cerebrus Ltd | Chemical compounds VI |
| GB9819035D0 (en) | 1998-09-01 | 1998-10-28 | Cerebrus Res Ltd | Chemical compounds VII |
| GB9819020D0 (en) | 1998-09-01 | 1998-10-28 | Cerebrus Ltd | Chemical compounds III |
| JP2002523451A (ja) | 1998-09-01 | 2002-07-30 | ブリストル−マイヤーズ スクイブ カンパニー | カリウムチャネル抑制剤および方法 |
| GB9819019D0 (en) | 1998-09-01 | 1998-10-28 | Cerebrus Ltd | Chemical compounds II |
| JP2000191533A (ja) | 1998-10-19 | 2000-07-11 | Eisai Co Ltd | 鎮痛剤 |
| AU1738900A (en) | 1998-11-19 | 2000-06-05 | Nortran Pharmaceuticals Inc. | Serotonin ligands as pro-erectile compounds |
| CA2361516A1 (en) | 1999-01-27 | 2000-08-03 | Jeffrey Thomas Mullaney | Aminoalkylbenzofurans as serotonin (5-ht(2c)) agonists |
| CA2374898C (en) | 1999-05-21 | 2009-12-08 | Biovitrum Ab | Pyrazinyl-piperazine compounds, their use and preparation |
| AU2001279056A1 (en) * | 2000-07-28 | 2002-02-13 | Goodrich Corporation | Optical waveguides and methods for making the same |
| SE0004245D0 (sv) * | 2000-11-20 | 2000-11-20 | Pharmacia Ab | Novel compounds and their use |
| AU2426602A (en) | 2000-11-20 | 2002-05-27 | Biovitrum Ab | Piperazinylpyrazine compounds as agonist or antagonist of serotonin 5ht-2 receptor |
| TWI245761B (en) | 2001-03-01 | 2005-12-21 | Telik Inc | Antagonists of MCP-1 function and methods of use thereof |
| WO2002081443A1 (en) | 2001-04-09 | 2002-10-17 | Chiron Corporation | Novel guanidino compounds |
| US6825198B2 (en) | 2001-06-21 | 2004-11-30 | Pfizer Inc | 5-HT receptor ligands and uses thereof |
| US6953787B2 (en) | 2002-04-12 | 2005-10-11 | Arena Pharmaceuticals, Inc. | 5HT2C receptor modulators |
| CA2521619A1 (en) | 2003-04-11 | 2004-10-28 | Taigen Biotechnology | Aminoquinoline compounds |
| US7101881B2 (en) | 2003-06-11 | 2006-09-05 | Pfizer Inc | Tetrahydroquinolines |
| TW200612918A (en) | 2004-07-29 | 2006-05-01 | Threshold Pharmaceuticals Inc | Lonidamine analogs |
-
2006
- 2006-03-21 NZ NZ560917A patent/NZ560917A/en not_active IP Right Cessation
- 2006-03-21 EP EP06710585A patent/EP1869000A1/en not_active Withdrawn
- 2006-03-21 BR BRPI0609268-3A patent/BRPI0609268A2/pt not_active IP Right Cessation
- 2006-03-21 AU AU2006228378A patent/AU2006228378A1/en not_active Abandoned
- 2006-03-21 AP AP2007004144A patent/AP2007004144A0/xx unknown
- 2006-03-21 WO PCT/IB2006/000655 patent/WO2006103511A1/en not_active Ceased
- 2006-03-21 EA EA200701853A patent/EA200701853A1/ru unknown
- 2006-03-21 CA CA2602348A patent/CA2602348C/en not_active Expired - Fee Related
- 2006-03-21 JP JP2008503608A patent/JP4318744B2/ja not_active Expired - Fee Related
- 2006-03-21 KR KR1020077022374A patent/KR100894006B1/ko not_active Expired - Fee Related
- 2006-03-21 MX MX2007012082A patent/MX2007012082A/es active IP Right Grant
- 2006-03-28 PE PE2006000343A patent/PE20061333A1/es not_active Application Discontinuation
- 2006-03-29 GT GT200600128A patent/GT200600128A/es unknown
- 2006-03-29 AR ARP060101218A patent/AR054021A1/es unknown
- 2006-03-30 UY UY29446A patent/UY29446A1/es not_active Application Discontinuation
- 2006-03-30 DO DO2006000076A patent/DOP2006000076A/es unknown
- 2006-03-30 NL NL1031473A patent/NL1031473C2/nl not_active IP Right Cessation
- 2006-03-30 TW TW095111125A patent/TW200722423A/zh unknown
- 2006-03-31 US US11/395,327 patent/US7507732B2/en not_active Expired - Fee Related
-
2007
- 2007-08-23 IL IL185492A patent/IL185492A0/en unknown
- 2007-08-27 NO NO20074368A patent/NO20074368L/no not_active Application Discontinuation
- 2007-09-19 CR CR9386A patent/CR9386A/es not_active Application Discontinuation
- 2007-09-28 TN TNP2007000367A patent/TNSN07367A1/fr unknown
- 2007-09-28 MA MA30262A patent/MA29354B1/fr unknown
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