JP2008534433A5 - - Google Patents
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- Publication number
- JP2008534433A5 JP2008534433A5 JP2007544754A JP2007544754A JP2008534433A5 JP 2008534433 A5 JP2008534433 A5 JP 2008534433A5 JP 2007544754 A JP2007544754 A JP 2007544754A JP 2007544754 A JP2007544754 A JP 2007544754A JP 2008534433 A5 JP2008534433 A5 JP 2008534433A5
- Authority
- JP
- Japan
- Prior art keywords
- acid
- tartrate
- magnesium
- fumarate
- citrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002253 acid Substances 0.000 claims 9
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims 4
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims 3
- 229940095064 tartrate Drugs 0.000 claims 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 claims 2
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 claims 2
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims 2
- RDHQFKQIGNGIED-MRVPVSSYSA-N O-acetyl-L-carnitine Chemical compound CC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C RDHQFKQIGNGIED-MRVPVSSYSA-N 0.000 claims 2
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 claims 2
- 229910019142 PO4 Inorganic materials 0.000 claims 2
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims 2
- 229940009098 aspartate Drugs 0.000 claims 2
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 claims 2
- -1 mucate Chemical compound 0.000 claims 2
- 235000016709 nutrition Nutrition 0.000 claims 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 2
- 239000010452 phosphate Substances 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- NDVRKEKNSBMTAX-BTVCFUMJSA-N (2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanal;phosphoric acid Chemical compound OP(O)(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O NDVRKEKNSBMTAX-BTVCFUMJSA-N 0.000 claims 1
- XOAAWQZATWQOTB-UHFFFAOYSA-M 2-aminoethanesulfonate Chemical compound NCCS([O-])(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-M 0.000 claims 1
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 claims 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims 1
- 208000001640 Fibromyalgia Diseases 0.000 claims 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 claims 1
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 claims 1
- DTQVDTLACAAQTR-UHFFFAOYSA-M Trifluoroacetate Chemical compound [O-]C(=O)C(F)(F)F DTQVDTLACAAQTR-UHFFFAOYSA-M 0.000 claims 1
- AWUCVROLDVIAJX-UHFFFAOYSA-N alpha-glycerophosphate Natural products OCC(O)COP(O)(O)=O AWUCVROLDVIAJX-UHFFFAOYSA-N 0.000 claims 1
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 claims 1
- 229960001231 choline Drugs 0.000 claims 1
- 229960005336 magnesium citrate Drugs 0.000 claims 1
- 235000002538 magnesium citrate Nutrition 0.000 claims 1
- 239000004337 magnesium citrate Substances 0.000 claims 1
- 229940095060 magnesium tartrate Drugs 0.000 claims 1
- MUZDLCBWNVUYIR-ZVGUSBNCSA-L magnesium;(2r,3r)-2,3-dihydroxybutanedioate Chemical compound [Mg+2].[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O MUZDLCBWNVUYIR-ZVGUSBNCSA-L 0.000 claims 1
- QUIOHQITLKCGNW-TYYBGVCCSA-L magnesium;(e)-but-2-enedioate Chemical compound [Mg+2].[O-]C(=O)\C=C\C([O-])=O QUIOHQITLKCGNW-TYYBGVCCSA-L 0.000 claims 1
- YZURQOBSFRVSEB-UHFFFAOYSA-L magnesium;2-aminoethanesulfonate Chemical compound [Mg+2].NCCS([O-])(=O)=O.NCCS([O-])(=O)=O YZURQOBSFRVSEB-UHFFFAOYSA-L 0.000 claims 1
- PXQPEWDEAKTCGB-UHFFFAOYSA-N orotic acid Chemical compound OC(=O)C1=CC(=O)NC(=O)N1 PXQPEWDEAKTCGB-UHFFFAOYSA-N 0.000 claims 1
- AWUCVROLDVIAJX-GSVOUGTGSA-N sn-glycerol 3-phosphate Chemical compound OC[C@@H](O)COP(O)(O)=O AWUCVROLDVIAJX-GSVOUGTGSA-N 0.000 claims 1
- 229940066528 trichloroacetate Drugs 0.000 claims 1
- YNJBWRMUSHSURL-UHFFFAOYSA-N trichloroacetic acid Chemical compound OC(=O)C(Cl)(Cl)Cl YNJBWRMUSHSURL-UHFFFAOYSA-N 0.000 claims 1
- PLSARIKBYIPYPF-UHFFFAOYSA-H trimagnesium dicitrate Chemical compound [Mg+2].[Mg+2].[Mg+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O PLSARIKBYIPYPF-UHFFFAOYSA-H 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000606A ITRM20040606A1 (it) | 2004-12-13 | 2004-12-13 | Uso della acetil l-carnitina per il trattamento della sindrome fibromialgica. |
| ITRM2004A000606 | 2004-12-13 | ||
| PCT/EP2005/012054 WO2006063639A1 (en) | 2004-12-13 | 2005-11-10 | Use of acetyl l-carnitine for the treatment of fibromyalgic syndrome |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008534433A JP2008534433A (ja) | 2008-08-28 |
| JP2008534433A5 true JP2008534433A5 (enExample) | 2008-12-25 |
| JP5057990B2 JP5057990B2 (ja) | 2012-10-24 |
Family
ID=35708966
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007544754A Expired - Fee Related JP5057990B2 (ja) | 2004-12-13 | 2005-11-10 | 線維筋痛症候群の治療のためのアセチルｌ−カルニチンの使用 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US8013016B2 (enExample) |
| EP (1) | EP1824472B1 (enExample) |
| JP (1) | JP5057990B2 (enExample) |
| KR (1) | KR101240182B1 (enExample) |
| AT (1) | ATE419847T1 (enExample) |
| CA (1) | CA2585560C (enExample) |
| CY (1) | CY1110576T1 (enExample) |
| DE (1) | DE602005012317D1 (enExample) |
| DK (1) | DK1824472T3 (enExample) |
| ES (1) | ES2320788T3 (enExample) |
| IT (1) | ITRM20040606A1 (enExample) |
| MX (1) | MX2007006954A (enExample) |
| PL (1) | PL1824472T3 (enExample) |
| PT (1) | PT1824472E (enExample) |
| SI (1) | SI1824472T1 (enExample) |
| WO (1) | WO2006063639A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2840363A1 (en) * | 2011-06-24 | 2012-12-27 | K-Pax Pharmaceuticals, Inc. | Compositions comprising a central nervous system stimulant and select micronutrients useful in the treatment of chronic fatigue |
| ES2962933T3 (es) | 2020-12-14 | 2024-03-21 | Ims Gear Se & Co Kgaa | Procedimiento para la corrección de una señal de medición dependiente del tiempo de una unidad de motor-engranaje, así como procedimiento para detectar desgaste y/o un deterioro de la misma mediante este procedimiento de corrección |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1150396B (it) * | 1982-12-09 | 1986-12-10 | Sigma Tau Ind Farmaceuti | Impiego di alcanoil l-carnitine per il trattamento terapeutico di miopa tie e distrofie muscolari |
| EP0681839A3 (en) * | 1994-05-12 | 1997-11-12 | Hirohiko Kuratsune | A pharmaceutical preparation comprising an acylcarnitine |
| US6025368A (en) * | 1997-02-25 | 2000-02-15 | Celtrix Pharmaceuticals, Inc. | Method for treating the symptoms of chronic stress-related disorders using IGF |
| US5935949A (en) * | 1998-03-20 | 1999-08-10 | Trustees Of Dartmouth College | Use of androgen therapy in fibromyalgia and chronic fatigue syndrome |
| US6803387B1 (en) | 1999-03-19 | 2004-10-12 | Abbott Gmbh & Co. Kg | Treatment of neuropathic pain or fibromyalgia |
| ITRM20010293A1 (it) | 2001-05-29 | 2002-11-29 | Sigma Tau Ind Farmaceuti | Uso della acetil-l-carnetina per la preparazione di un medicamento per la prevenzione del dolore. |
| KR101027570B1 (ko) * | 2002-05-03 | 2011-04-06 | 이스라엘 인스티튜트 포 바이올로지컬 리서치 | 중추 및 말초 신경계 장애의 치료를 위한 방법 및 조성물, 및 그에 유용한 신규 화합물 |
-
2004
- 2004-12-13 IT IT000606A patent/ITRM20040606A1/it unknown
-
2005
- 2005-11-10 SI SI200530579T patent/SI1824472T1/sl unknown
- 2005-11-10 US US11/719,447 patent/US8013016B2/en not_active Expired - Fee Related
- 2005-11-10 CA CA2585560A patent/CA2585560C/en not_active Expired - Fee Related
- 2005-11-10 JP JP2007544754A patent/JP5057990B2/ja not_active Expired - Fee Related
- 2005-11-10 AT AT05807584T patent/ATE419847T1/de active
- 2005-11-10 PL PL05807584T patent/PL1824472T3/pl unknown
- 2005-11-10 MX MX2007006954A patent/MX2007006954A/es active IP Right Grant
- 2005-11-10 WO PCT/EP2005/012054 patent/WO2006063639A1/en not_active Ceased
- 2005-11-10 EP EP05807584A patent/EP1824472B1/en not_active Expired - Lifetime
- 2005-11-10 DE DE602005012317T patent/DE602005012317D1/de not_active Expired - Lifetime
- 2005-11-10 PT PT05807584T patent/PT1824472E/pt unknown
- 2005-11-10 DK DK05807584T patent/DK1824472T3/da active
- 2005-11-10 KR KR1020077015272A patent/KR101240182B1/ko not_active Expired - Fee Related
- 2005-11-10 ES ES05807584T patent/ES2320788T3/es not_active Expired - Lifetime
-
2009
- 2009-03-31 CY CY20091100383T patent/CY1110576T1/el unknown
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