JP2008533022A5 - - Google Patents
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- Publication number
- JP2008533022A5 JP2008533022A5 JP2008500871A JP2008500871A JP2008533022A5 JP 2008533022 A5 JP2008533022 A5 JP 2008533022A5 JP 2008500871 A JP2008500871 A JP 2008500871A JP 2008500871 A JP2008500871 A JP 2008500871A JP 2008533022 A5 JP2008533022 A5 JP 2008533022A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- aminopterin
- patient
- cycle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/078,271 US7312217B2 (en) | 2005-03-11 | 2005-03-11 | Aminopterin dosage forms and methods for inflammatory disorders |
| US11/078,271 | 2005-03-11 | ||
| PCT/US2006/008233 WO2006098979A2 (en) | 2005-03-11 | 2006-03-08 | Aminopterin dosage forms and methods for inflammatory disorders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013098407A Division JP2013209384A (ja) | 2005-03-11 | 2013-05-08 | 炎症性疾患に対するアミノプテリン投与形態及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008533022A JP2008533022A (ja) | 2008-08-21 |
| JP2008533022A5 true JP2008533022A5 (cg-RX-API-DMAC7.html) | 2009-07-16 |
| JP5791864B2 JP5791864B2 (ja) | 2015-10-07 |
Family
ID=36971856
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008500871A Active JP5791864B2 (ja) | 2005-03-11 | 2006-03-08 | 炎症性疾患に対するアミノプテリン投与形態及び方法 |
| JP2013098407A Withdrawn JP2013209384A (ja) | 2005-03-11 | 2013-05-08 | 炎症性疾患に対するアミノプテリン投与形態及び方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013098407A Withdrawn JP2013209384A (ja) | 2005-03-11 | 2013-05-08 | 炎症性疾患に対するアミノプテリン投与形態及び方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (5) | US7312217B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1855682B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP5791864B2 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2658070T3 (cg-RX-API-DMAC7.html) |
| PL (1) | PL1855682T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2006098979A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1789391B1 (en) | 2004-07-23 | 2017-06-28 | Endocyte, Inc. | Bivalent linkers and conjugates thereof |
| US7312217B2 (en) * | 2005-03-11 | 2007-12-25 | Syntrix Biosystems, Inc. | Aminopterin dosage forms and methods for inflammatory disorders |
| CN101678124A (zh) | 2007-03-14 | 2010-03-24 | 恩多塞特公司 | 结合配体连接的微管溶素递药缀合物 |
| US9877965B2 (en) | 2007-06-25 | 2018-01-30 | Endocyte, Inc. | Vitamin receptor drug delivery conjugates for treating inflammation |
| EP3569251A1 (en) | 2007-06-25 | 2019-11-20 | Endocyte, Inc. | Conjugates containing hydrophilic spacer linkers |
| DK2384119T3 (en) * | 2009-01-24 | 2015-10-12 | Aminopterin Llc | A pharmaceutical composition comprising racemic aminopterin |
| CA2812543A1 (en) * | 2010-09-27 | 2012-04-12 | Endocyte, Inc. | Folate conjugates for treating inflammation of the eye |
| WO2013126797A1 (en) | 2012-02-24 | 2013-08-29 | Purdue Research Foundation | Cholecystokinin b receptor targeting for imaging and therapy |
| US20140080175A1 (en) | 2012-03-29 | 2014-03-20 | Endocyte, Inc. | Processes for preparing tubulysin derivatives and conjugates thereof |
| KR20150070318A (ko) | 2012-10-16 | 2015-06-24 | 엔도사이트, 인코포레이티드 | 비천연 아미노산을 함유하는 약물 전달 컨쥬게이트 및 사용 방법 |
| CN108135941B (zh) * | 2015-08-19 | 2021-07-27 | 儿研所儿童医学中心 | 用于治疗移植物抗宿主病的组合物和方法 |
| CN106046005A (zh) * | 2016-08-19 | 2016-10-26 | 常州市新鸿医药化工技术有限公司 | 一种叶酸合成方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2575168A (en) | 1948-07-22 | 1951-11-13 | American Cyanamid Co | Rodenticide comprising 4-aminopteroylglutamic acid |
| US3536809A (en) | 1969-02-17 | 1970-10-27 | Alza Corp | Medication method |
| US3598123A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
| US3630200A (en) | 1969-06-09 | 1971-12-28 | Alza Corp | Ocular insert |
| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| US4079056A (en) | 1975-03-31 | 1978-03-14 | The United States Of America As Represented By The Department Of Health, Education And Welfare | Method of making pteridine compounds |
| US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
| CH630380A5 (de) | 1977-08-12 | 1982-06-15 | Lonza Ag | Verfahren zur herstellung von l-methotrexat. |
| GB8322007D0 (en) | 1983-08-16 | 1983-09-21 | Wellcome Found | Pharmaceutical delivery system |
| FR2590255B1 (fr) | 1985-11-19 | 1987-12-24 | Rhone Poulenc Sante | Procede de preparation de derives de la pteridine |
| US6489346B1 (en) * | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
| US6673908B1 (en) * | 1999-02-22 | 2004-01-06 | Nuvelo, Inc. | Tumor necrosis factor receptor 2 |
| MXPA03001247A (es) * | 2000-08-10 | 2003-10-15 | Uab Research Foundation | Composiciones que contienen inhibidor de dihidrofolato reductasa y folato. |
| US20040176381A1 (en) * | 2003-03-06 | 2004-09-09 | Walsh Michael J. | Methotrexate compliance packaging |
| US7612071B2 (en) * | 2004-03-12 | 2009-11-03 | Syntrix Biosystems, Inc. | Compositions and methods employing aminopterin |
| DE102004016355A1 (de) * | 2004-04-02 | 2005-11-03 | Rösner Research GmbH & Co.KG | Herstellung und Verwendung des Konjugats Methotrexat-Albumin als Mittel zur Immunosuppression bei GVHD |
| US7312217B2 (en) | 2005-03-11 | 2007-12-25 | Syntrix Biosystems, Inc. | Aminopterin dosage forms and methods for inflammatory disorders |
| DK2384119T3 (en) * | 2009-01-24 | 2015-10-12 | Aminopterin Llc | A pharmaceutical composition comprising racemic aminopterin |
-
2005
- 2005-03-11 US US11/078,271 patent/US7312217B2/en not_active Expired - Lifetime
-
2006
- 2006-03-08 PL PL06748317T patent/PL1855682T3/pl unknown
- 2006-03-08 WO PCT/US2006/008233 patent/WO2006098979A2/en not_active Ceased
- 2006-03-08 ES ES06748317.2T patent/ES2658070T3/es active Active
- 2006-03-08 EP EP06748317.2A patent/EP1855682B1/en active Active
- 2006-03-08 JP JP2008500871A patent/JP5791864B2/ja active Active
-
2007
- 2007-10-25 US US11/924,250 patent/US20080096893A1/en not_active Abandoned
- 2007-10-30 US US11/928,890 patent/US8129383B2/en active Active
-
2012
- 2012-01-29 US US13/360,778 patent/US20120128703A1/en not_active Abandoned
-
2013
- 2013-05-08 JP JP2013098407A patent/JP2013209384A/ja not_active Withdrawn
-
2016
- 2016-10-14 US US15/294,642 patent/US9867828B2/en not_active Expired - Fee Related