JP2008528534A5 - - Google Patents
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- Publication number
- JP2008528534A5 JP2008528534A5 JP2007552587A JP2007552587A JP2008528534A5 JP 2008528534 A5 JP2008528534 A5 JP 2008528534A5 JP 2007552587 A JP2007552587 A JP 2007552587A JP 2007552587 A JP2007552587 A JP 2007552587A JP 2008528534 A5 JP2008528534 A5 JP 2008528534A5
- Authority
- JP
- Japan
- Prior art keywords
- opioid
- salt
- dosage form
- less
- controlled release
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0501638.1 | 2005-01-28 | ||
| GBGB0501638.1A GB0501638D0 (en) | 2005-01-28 | 2005-01-28 | Particulates |
| GBPCT/GB2005/050014 | 2005-02-11 | ||
| PCT/GB2005/050014 WO2005079760A1 (en) | 2004-02-12 | 2005-02-11 | Particulates |
| US67050605P | 2005-04-12 | 2005-04-12 | |
| US60/670,506 | 2005-04-12 | ||
| US73033905P | 2005-10-26 | 2005-10-26 | |
| US60/730,339 | 2005-10-26 | ||
| PCT/EP2006/000727 WO2006079550A2 (en) | 2005-01-28 | 2006-01-27 | Alcohol resistant dosage forms |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012284017A Division JP2013100306A (ja) | 2005-01-28 | 2012-12-27 | 耐アルコール性剤形 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008528534A JP2008528534A (ja) | 2008-07-31 |
| JP2008528534A5 true JP2008528534A5 (enExample) | 2008-10-23 |
| JP5704789B2 JP5704789B2 (ja) | 2015-04-22 |
Family
ID=36297284
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007552587A Expired - Lifetime JP5704789B2 (ja) | 2005-01-28 | 2006-01-27 | 耐アルコール性剤形 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20070259045A1 (enExample) |
| EP (4) | EP3228308A1 (enExample) |
| JP (1) | JP5704789B2 (enExample) |
| KR (2) | KR20090029856A (enExample) |
| CN (1) | CN101132772B (enExample) |
| AP (1) | AP2274A (enExample) |
| AU (1) | AU2006208627B8 (enExample) |
| BR (1) | BRPI0606339A2 (enExample) |
| CA (1) | CA2594373A1 (enExample) |
| EA (1) | EA015615B1 (enExample) |
| GE (1) | GEP20105052B (enExample) |
| IL (1) | IL184858A (enExample) |
| MX (1) | MX2007009162A (enExample) |
| WO (1) | WO2006079550A2 (enExample) |
Families Citing this family (85)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2266564B1 (en) | 1997-12-22 | 2013-03-13 | Euro-Celtique S.A. | Pharmaceutical oral dosage form comprising a combination of an opioid agonist and an opioid antagonist |
| US6375957B1 (en) | 1997-12-22 | 2002-04-23 | Euro-Celtique, S.A. | Opioid agonist/opioid antagonist/acetaminophen combinations |
| JP4522652B2 (ja) | 2001-05-11 | 2010-08-11 | エンドー ファーマシューティカルズ, インコーポレイティド | 乱用防止制御放出オピオイド投薬形態 |
| LT2425824T (lt) | 2002-04-05 | 2017-07-25 | Euro-Celtique S.A. | Farmacinis preparatas, turintis oksikodono ir naloksono |
| US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
| US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
| DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
| TWI350762B (en) * | 2004-02-12 | 2011-10-21 | Euro Celtique Sa | Particulates |
| GB0403098D0 (en) * | 2004-02-12 | 2004-03-17 | Euro Celtique Sa | Extrusion |
| DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
| DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| EP1702558A1 (en) | 2005-02-28 | 2006-09-20 | Euro-Celtique S.A. | Method and device for the assessment of bowel function |
| EP1810678A1 (de) | 2006-01-19 | 2007-07-25 | Holger Lars Hermann | Verwendung einer Kombination von Morphin und Naloxon zur Drogensubstitution |
| US20090317355A1 (en) * | 2006-01-21 | 2009-12-24 | Abbott Gmbh & Co. Kg, | Abuse resistant melt extruded formulation having reduced alcohol interaction |
| US20070212414A1 (en) * | 2006-03-08 | 2007-09-13 | Penwest Pharmaceuticals Co. | Ethanol-resistant sustained release formulations |
| US20080119501A1 (en) * | 2006-04-28 | 2008-05-22 | Hein William A | Immediate release oxymorphone compositions and methods of using same |
| US20080069891A1 (en) * | 2006-09-15 | 2008-03-20 | Cima Labs, Inc. | Abuse resistant drug formulation |
| US20080075771A1 (en) * | 2006-07-21 | 2008-03-27 | Vaughn Jason M | Hydrophilic opioid abuse deterrent delivery system using opioid antagonists |
| SA07280459B1 (ar) | 2006-08-25 | 2011-07-20 | بيورديو فارما إل. بي. | أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني |
| DE102006051020A1 (de) * | 2006-10-26 | 2008-04-30 | Evonik Röhm Gmbh | Verwendung von (Meth)acrylat-Copolymeren in Retard-Arzneiformen zur Verringerung des Einflusses von Ethanol auf die Wirkstofffreisetzung |
| NZ580972A (en) | 2007-06-04 | 2012-02-24 | Egalet Ltd | Controlled release pharmaceutical compositions for prolonged effect |
| JP5965583B2 (ja) | 2007-08-13 | 2016-08-10 | インスピリオン デリバリー テクノロジーズ エルエルシー | 乱用抵抗性医薬組成物、その使用方法および作製方法 |
| MX2010003032A (es) * | 2007-09-21 | 2010-04-09 | Evonik R Hm Gmbh | Composicion farmaceutica opioide de liberacion controlada ph dependiente con resistencia contra la influencia del etanol. |
| CN101801356B (zh) * | 2007-09-21 | 2016-10-19 | 赢创罗姆有限公司 | 耐受乙醇影响的非阿片类的pH依赖性受控释放的药物组合物 |
| TW200950776A (en) * | 2008-01-24 | 2009-12-16 | Abbott Gmbh & Co Kg | Abuse resistant melt extruded formulation having reduced alcohol interaction |
| JP5774853B2 (ja) | 2008-01-25 | 2015-09-09 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 医薬投薬形 |
| US9226907B2 (en) | 2008-02-01 | 2016-01-05 | Abbvie Inc. | Extended release hydrocodone acetaminophen and related methods and uses thereof |
| AU2009223061B2 (en) | 2008-03-11 | 2014-10-09 | Depomed Inc. | Gastric retentive extended-release dosage forms comprising combinations of a non-opioid analgesic and an opioid analgesic |
| US8372432B2 (en) | 2008-03-11 | 2013-02-12 | Depomed, Inc. | Gastric retentive extended-release dosage forms comprising combinations of a non-opioid analgesic and an opioid analgesic |
| MX2010012039A (es) | 2008-05-09 | 2010-11-30 | Gruenenthal Gmbh | Proceso para la preparacion de una formulacion de polvo intermedia y una forma de dosificacion solida final bajo el uso de un paso de congelacion por rocio. |
| AU2009294308B2 (en) * | 2008-09-18 | 2013-05-30 | Purdue Pharma L.P. | Pharmaceutical dosage forms comprising poly(e-caprolactone) |
| CA2738078C (en) * | 2008-09-24 | 2015-12-29 | Evonik Operations Gmbh | Ph-dependent controlled release pharmaceutical opioid composition with resistance against the influence of ethanol |
| CA2748409C (en) * | 2008-12-30 | 2016-03-08 | Farhad Farshi | Pharmaceutical formulations of olmesartan |
| WO2010089132A1 (en) | 2009-02-06 | 2010-08-12 | Egalet A/S | Immediate release composition resistant to abuse by intake of alcohol |
| HUE042105T2 (hu) | 2009-03-10 | 2019-06-28 | Euro Celtique Sa | Oxikodont és naloxont tartalmazó azonnali hatóanyagleadású orális gyógyászati készítmények |
| JP5619130B2 (ja) * | 2009-03-18 | 2014-11-05 | エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツングEvonik RoehmGmbH | 中性ビニルポリマーおよび賦形剤を含むコーティングを使用するエタノールの影響に対する耐性を有する制御放出性医薬組成物 |
| CA2755814A1 (en) * | 2009-03-18 | 2010-09-23 | Evonik Roehm Gmbh | Controlled release pharmaceutical composition with resistance against the influence of ethanol employing a coating comprising a polymer mixture and excipients |
| GB0909680D0 (en) * | 2009-06-05 | 2009-07-22 | Euro Celtique Sa | Dosage form |
| EP2445487A2 (en) | 2009-06-24 | 2012-05-02 | Egalet Ltd. | Controlled release formulations |
| BR112012001547A2 (pt) | 2009-07-22 | 2016-03-08 | Gruenenthal Gmbh | forma de dosagem farmacêutica extrusada por fusão a quente |
| ES2428938T3 (es) | 2009-07-22 | 2013-11-12 | Grünenthal GmbH | Forma de dosificación resistente a la manipulación y estabilizada frente a la oxidación |
| US8597681B2 (en) | 2009-12-22 | 2013-12-03 | Mallinckrodt Llc | Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans |
| US9198861B2 (en) | 2009-12-22 | 2015-12-01 | Mallinckrodt Llc | Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans |
| CN102821757B (zh) | 2010-02-03 | 2016-01-20 | 格吕伦塔尔有限公司 | 通过挤出机制备粉末状药物组合物 |
| AU2011252040C1 (en) | 2010-05-10 | 2015-04-02 | Euro-Celtique S.A. | Manufacturing of active-free granules and tablets comprising the same |
| CA2798885C (en) * | 2010-05-10 | 2014-11-18 | Euro-Celtique S.A. | Combination of active loaded granules with additional actives |
| BR112012028773A2 (pt) * | 2010-05-10 | 2016-07-19 | Euro Celtique Sa | composições farmacêuticas compreendendo hidromorfona e naloxona |
| CN103179954A (zh) | 2010-09-02 | 2013-06-26 | 格吕伦塔尔有限公司 | 包含阴离子聚合物的抗破碎剂型 |
| CA2808219C (en) | 2010-09-02 | 2019-05-14 | Gruenenthal Gmbh | Tamper resistant dosage form comprising inorganic salt |
| GB201020895D0 (en) * | 2010-12-09 | 2011-01-26 | Euro Celtique Sa | Dosage form |
| US9050335B1 (en) | 2011-05-17 | 2015-06-09 | Mallinckrodt Llc | Pharmaceutical compositions for extended release of oxycodone and acetaminophen resulting in a quick onset and prolonged period of analgesia |
| US8741885B1 (en) | 2011-05-17 | 2014-06-03 | Mallinckrodt Llc | Gastric retentive extended release pharmaceutical compositions |
| US8858963B1 (en) | 2011-05-17 | 2014-10-14 | Mallinckrodt Llc | Tamper resistant composition comprising hydrocodone and acetaminophen for rapid onset and extended duration of analgesia |
| AT511581A1 (de) | 2011-05-26 | 2012-12-15 | G L Pharma Gmbh | Orale retardierende formulierung |
| EP2714015B1 (en) * | 2011-06-01 | 2017-03-15 | FMC Corporation | Controlled release solid dose forms |
| CA2839123A1 (en) | 2011-07-29 | 2013-02-07 | Grunenthal Gmbh | Tamper-resistant tablet providing immediate drug release |
| PL2736497T3 (pl) | 2011-07-29 | 2018-01-31 | Gruenenthal Gmbh | Tabletka odporna na ingerencję, zapewniająca natychmiastowe uwalnianie leku |
| ES2641437T3 (es) * | 2011-09-16 | 2017-11-10 | Purdue Pharma Lp | Formulaciones farmacéuticas resistentes a la manipulación indebida |
| JP6246720B2 (ja) * | 2011-10-18 | 2017-12-13 | パーデュー、ファーマ、リミテッド、パートナーシップ | アクリルポリマー製剤 |
| MX356421B (es) | 2012-02-28 | 2018-05-29 | Gruenenthal Gmbh | Forma de dosificacion resistente a la manipulacion indebida que comprende un compuesto farmacologicamente activo y un polimero anionico. |
| PL2838512T3 (pl) * | 2012-04-18 | 2018-12-31 | Grünenthal GmbH | Farmaceutyczna postać dawkowania odporna na niewłaściwe użycie i odporna na uderzeniowe uwalnianie dawki |
| US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
| CA2795324C (en) * | 2012-11-09 | 2015-07-14 | Purdue Pharma | Pharmaceutical compositions comprising hydromorphone and naloxone |
| AP2015008579A0 (en) | 2013-02-05 | 2015-07-31 | Purdue Pharma Lp | Tamper resistant pharmaceutical formulations |
| CA2907428A1 (en) | 2013-03-15 | 2014-09-18 | Inspirion Delivery Technologies, Llc | Abuse deterrent compositions and methods of use |
| US10751287B2 (en) | 2013-03-15 | 2020-08-25 | Purdue Pharma L.P. | Tamper resistant pharmaceutical formulations |
| MX371432B (es) | 2013-05-29 | 2020-01-30 | Gruenenthal Gmbh | Forma de dosificacion resistente al uso indebido que contiene una o mas particulas. |
| WO2014191396A1 (en) | 2013-05-29 | 2014-12-04 | Grünenthal GmbH | Tamper resistant dosage form with bimodal release profile |
| US10624862B2 (en) | 2013-07-12 | 2020-04-21 | Grünenthal GmbH | Tamper-resistant dosage form containing ethylene-vinyl acetate polymer |
| EP3024461B1 (en) | 2013-07-23 | 2020-05-13 | Euro-Celtique S.A. | A combination of oxycodone and naloxone for use in treating pain in patients suffering from pain and a disease resulting in intestinal dysbiosis and/or increasing the risk for intestinal bacterial translocation |
| EP3068397A1 (en) | 2013-11-13 | 2016-09-21 | Euro-Celtique S.A. | Hydromorphone and naloxone for treatment of pain and opioid bowel dysfunction syndrome |
| WO2015078891A1 (en) | 2013-11-26 | 2015-06-04 | Farmaceutici Formenti S.P.A. | Preparation of a powdery pharmaceutical composition by means of cryo-milling |
| US20150320690A1 (en) | 2014-05-12 | 2015-11-12 | Grünenthal GmbH | Tamper resistant immediate release capsule formulation comprising tapentadol |
| EP3148512A1 (en) | 2014-05-26 | 2017-04-05 | Grünenthal GmbH | Multiparticles safeguarded against ethanolic dose-dumping |
| US10729685B2 (en) | 2014-09-15 | 2020-08-04 | Ohemo Life Sciences Inc. | Orally administrable compositions and methods of deterring abuse by intranasal administration |
| BR112017021475A2 (pt) | 2015-04-24 | 2018-07-10 | Gruenenthal Gmbh | forma de dosagem resistente à adulteração (tamper) com liberação imediata e resistência contra extração de solvente |
| AU2016319203A1 (en) | 2015-09-10 | 2018-02-22 | Grünenthal GmbH | Protecting oral overdose with abuse deterrent immediate release formulations |
| US9943513B1 (en) | 2015-10-07 | 2018-04-17 | Banner Life Sciences Llc | Opioid abuse deterrent dosage forms |
| US10335405B1 (en) | 2016-05-04 | 2019-07-02 | Patheon Softgels, Inc. | Non-burst releasing pharmaceutical composition |
| US10335375B2 (en) | 2017-05-30 | 2019-07-02 | Patheon Softgels, Inc. | Anti-overingestion abuse deterrent compositions |
| WO2019089330A1 (en) | 2017-11-01 | 2019-05-09 | Edgemont Pharmceuticals, Llc Trust | Alcohol-resistant oral pharmaceutical compositions of lorazepam |
| US12161754B2 (en) | 2017-12-20 | 2024-12-10 | Purdue Pharma L.P. | Abuse deterrent morphine sulfate dosage forms |
| US20210401826A1 (en) * | 2018-08-13 | 2021-12-30 | Avekshan, Llc. | Abuse deterrent pharmaceutical formulations |
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-
2006
- 2006-01-27 EP EP17154428.1A patent/EP3228308A1/en not_active Withdrawn
- 2006-01-27 GE GEAP200610246A patent/GEP20105052B/en unknown
- 2006-01-27 EP EP10180425A patent/EP2319499A1/en not_active Withdrawn
- 2006-01-27 AP AP2007004099A patent/AP2274A/xx active
- 2006-01-27 WO PCT/EP2006/000727 patent/WO2006079550A2/en not_active Ceased
- 2006-01-27 EP EP10180364A patent/EP2289491A1/en not_active Withdrawn
- 2006-01-27 BR BRPI0606339-0A patent/BRPI0606339A2/pt not_active Application Discontinuation
- 2006-01-27 AU AU2006208627A patent/AU2006208627B8/en not_active Expired
- 2006-01-27 EP EP06703915A patent/EP1771160A2/en not_active Withdrawn
- 2006-01-27 JP JP2007552587A patent/JP5704789B2/ja not_active Expired - Lifetime
- 2006-01-27 KR KR1020097004935A patent/KR20090029856A/ko not_active Withdrawn
- 2006-01-27 CA CA002594373A patent/CA2594373A1/en not_active Abandoned
- 2006-01-27 MX MX2007009162A patent/MX2007009162A/es active IP Right Grant
- 2006-01-27 EA EA200701595A patent/EA015615B1/ru not_active IP Right Cessation
- 2006-01-27 US US11/574,778 patent/US20070259045A1/en not_active Abandoned
- 2006-01-27 CN CN2006800033121A patent/CN101132772B/zh not_active Expired - Lifetime
-
2007
- 2007-07-26 IL IL184858A patent/IL184858A/en active IP Right Grant
- 2007-08-27 KR KR1020077019593A patent/KR100905511B1/ko not_active Expired - Lifetime
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