JP2008526715A5 - - Google Patents

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Publication number
JP2008526715A5
JP2008526715A5 JP2007548841A JP2007548841A JP2008526715A5 JP 2008526715 A5 JP2008526715 A5 JP 2008526715A5 JP 2007548841 A JP2007548841 A JP 2007548841A JP 2007548841 A JP2007548841 A JP 2007548841A JP 2008526715 A5 JP2008526715 A5 JP 2008526715A5
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JP
Japan
Prior art keywords
alkyl
piperazin
butyl
cycloalkyl
alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007548841A
Other languages
English (en)
Japanese (ja)
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JP2008526715A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2006/050001 external-priority patent/WO2006072608A2/en
Publication of JP2008526715A publication Critical patent/JP2008526715A/ja
Publication of JP2008526715A5 publication Critical patent/JP2008526715A5/ja
Pending legal-status Critical Current

Links

JP2007548841A 2005-01-03 2006-01-02 神経精神障害の治療のためのアリールピペラジン誘導体 Pending JP2008526715A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200500004 2005-01-03
US64100605P 2005-01-04 2005-01-04
PCT/EP2006/050001 WO2006072608A2 (en) 2005-01-03 2006-01-02 Aryl piperazine derivatives for the treatment of neuropsychiatric disorders

Publications (2)

Publication Number Publication Date
JP2008526715A JP2008526715A (ja) 2008-07-24
JP2008526715A5 true JP2008526715A5 (https=) 2009-02-19

Family

ID=36600734

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007548841A Pending JP2008526715A (ja) 2005-01-03 2006-01-02 神経精神障害の治療のためのアリールピペラジン誘導体

Country Status (7)

Country Link
US (1) US20090238761A1 (https=)
EP (1) EP1836192A2 (https=)
JP (1) JP2008526715A (https=)
AU (1) AU2006204522A1 (https=)
CA (1) CA2593266A1 (https=)
NZ (1) NZ555491A (https=)
WO (1) WO2006072608A2 (https=)

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MX2009003390A (es) * 2006-10-13 2009-04-09 Univ Siena Derivados de aril piperazina utiles para el tratamiento de trastornos neuropsiquiatricos.
CA2672860C (en) * 2006-12-28 2013-01-29 Abbott Laboratories Inhibitors of poly(adp-ribose)polymerase
CA2690789C (en) 2007-06-15 2014-08-05 Amy Hauck Newman 4-phenylpiperazine derivatives with functionalized linkers as dopamine d3 receptor selective ligands and methods of use
CA2690748A1 (en) * 2007-06-25 2008-12-31 Neurogen Corporation Piperazinyl oxoalkyl tetrahydro-beta-carbolines and related analogues
WO2009095438A1 (en) * 2008-02-01 2009-08-06 Neurosearch A/S Novel aryl piperazine derivatives useful as modulators of dopamine and serotonin receptors
WO2010040808A1 (en) * 2008-10-10 2010-04-15 Neurosearch A/S Novel quinolinylamide derivatives useful as modulators of dopamine and serotonin receptors
WO2013138568A1 (en) 2012-03-16 2013-09-19 Vitae Pharmaceuticals, Inc. Liver x reception modulators
CN104203951B (zh) 2012-03-16 2016-11-02 生命医药公司 肝x受体调节剂
JP6345651B2 (ja) * 2012-05-09 2018-06-20 サノビオン ファーマシューティカルズ インクＳｕｎｏｖｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． ヘテロアリール化合物及びその使用方法
US9598387B2 (en) 2012-10-11 2017-03-21 Southern Research Institute Urea and amide derivatives of aminoalkylpiperazines and use thereof
MX2015014905A (es) * 2013-04-23 2016-03-07 Esteve Labor Dr Compuestos de pirazino - [1,2-a] indol, su preparacion y su uso en medicamentos.
WO2015014256A1 (en) 2013-07-29 2015-02-05 Sunshine Lake Pharma Co., Ltd. Substituted heteroaryl compounds and methods of use thereof
EP3083589B1 (en) 2013-12-20 2019-12-18 Sunshine Lake Pharma Co., Ltd. Substituted piperazine compounds and methods of use thereof
MA41168A (fr) * 2014-12-17 2017-10-24 Acraf Nouveaux composés antibactériens
CN107249592A (zh) * 2015-01-12 2017-10-13 雷维瓦药品公司 用于治疗阿尔茨海默病的方法
WO2016115039A1 (en) 2015-01-12 2016-07-21 Reviva Pharmaceuticals Inc. Methods for treating pulmonary hypertension
CN107206006A (zh) * 2015-01-12 2017-09-26 雷维瓦药品公司 用于治疗与帕金森病相关联的精神病的方法
US10316025B2 (en) 2015-06-03 2019-06-11 Sunshine Lake Pharma Co., Ltd. Substituted piperazine compounds and methods of use and use thereof
CN107787322B (zh) 2015-06-17 2023-07-07 辉瑞大药厂 三环化合物以及它们作为磷酸二酯酶抑制剂的用途
US11299476B2 (en) 2016-03-14 2022-04-12 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Dopamine D3 receptor selective antagonists/partial agonists; method of making; and use thereof
SI3429993T1 (sl) 2016-03-14 2021-09-30 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, National Institutes Of Health, Office Of Technology Transfer Selektivni antagonisti/delni agonisti dopaminskega receptorja D3; postopki izdelave; in uporaba le-teh
JP7017797B2 (ja) * 2017-02-24 2022-02-09 深▲チェン▼市霊蘭生物医薬科技有限公司 新規なドーパミンｄ３受容体選択的リガンド及びびその調製方法並びに医薬使用
TW201837034A (zh) * 2017-03-13 2018-10-16 日商大日本住友製藥股份有限公司 2, 6-二取代吡啶衍生物
GB201704325D0 (en) * 2017-03-17 2017-05-03 Argonaut Therapeutics Ltd Compounds
WO2020055725A1 (en) 2018-09-11 2020-03-19 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Dopamine d3 receptor selective antagonists/partial agonists and uses thereof
IL298941A (en) 2020-06-11 2023-02-01 Chdi Foundation Inc Heterocyclic compounds and imaging agents for the imaging of huntingtin protein

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