JP2008526695A5 - - Google Patents
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- Publication number
- JP2008526695A5 JP2008526695A5 JP2007548720A JP2007548720A JP2008526695A5 JP 2008526695 A5 JP2008526695 A5 JP 2008526695A5 JP 2007548720 A JP2007548720 A JP 2007548720A JP 2007548720 A JP2007548720 A JP 2007548720A JP 2008526695 A5 JP2008526695 A5 JP 2008526695A5
- Authority
- JP
- Japan
- Prior art keywords
- carbonyl
- amino
- naphthalene
- acid
- ylmethoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04031009.6 | 2004-12-30 | ||
| EP04031009A EP1676834A1 (en) | 2004-12-30 | 2004-12-30 | Fused bicyclic carboxamide derivates for use as CXCR2 inhibitors in the treatment of inflammation |
| PCT/EP2005/013624 WO2006069656A1 (en) | 2004-12-30 | 2005-12-17 | Fused bicyclic carboxamide derivatives for use as cxcr2 inhibitors in the treatment of inflammation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008526695A JP2008526695A (ja) | 2008-07-24 |
| JP2008526695A5 true JP2008526695A5 (enExample) | 2009-02-12 |
| JP5123667B2 JP5123667B2 (ja) | 2013-01-23 |
Family
ID=34928051
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007548720A Expired - Fee Related JP5123667B2 (ja) | 2004-12-30 | 2005-12-17 | 炎症の治療においてｃｘｃｒ２阻害剤として使用される縮合二環式カルボキサミド誘導体 |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US7919628B2 (enExample) |
| EP (2) | EP1676834A1 (enExample) |
| JP (1) | JP5123667B2 (enExample) |
| KR (1) | KR20070091634A (enExample) |
| CN (1) | CN101094830A (enExample) |
| AR (1) | AR055830A1 (enExample) |
| AT (1) | ATE543795T1 (enExample) |
| AU (1) | AU2005321609B2 (enExample) |
| BR (1) | BRPI0519452A2 (enExample) |
| CA (1) | CA2592430A1 (enExample) |
| IL (1) | IL184173A (enExample) |
| MA (1) | MA29113B1 (enExample) |
| MX (1) | MX2007007068A (enExample) |
| NO (1) | NO20073932L (enExample) |
| NZ (1) | NZ556192A (enExample) |
| PE (1) | PE20060855A1 (enExample) |
| RU (1) | RU2404962C2 (enExample) |
| TW (1) | TW200639141A (enExample) |
| UY (1) | UY29322A1 (enExample) |
| WO (1) | WO2006069656A1 (enExample) |
| ZA (1) | ZA200704089B (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1749000A4 (en) * | 2004-05-25 | 2009-12-30 | Metabolex Inc | BICYCLIC SUBSTITUTED TRIAZOLE AS PPAR MODULATORS AND METHOD FOR THE PRODUCTION THEREOF |
| EP1676834A1 (en) | 2004-12-30 | 2006-07-05 | Sanofi-Aventis Deutschland GmbH | Fused bicyclic carboxamide derivates for use as CXCR2 inhibitors in the treatment of inflammation |
| EP2044028B1 (en) | 2006-01-27 | 2012-05-16 | Fibrogen, Inc. | Cyanoisoquinoline compounds that stabilize hypoxia inducible factor (hif) |
| BRPI0710527B8 (pt) | 2006-04-04 | 2021-05-25 | Fibrogen Inc | compostos de pirrolo- e tiazolo-piridina e composição farmacêutica que os compreende |
| AU2007264114A1 (en) | 2006-06-28 | 2008-01-03 | Sanofi-Aventis | New CXCR2 inhibitors |
| EP2041072B1 (en) * | 2006-06-28 | 2013-09-11 | Sanofi | Cxcr2 antagonists |
| JP5232144B2 (ja) * | 2006-06-28 | 2013-07-10 | サノフイ | Ｃｘｃｒ２阻害剤 |
| EP2041073B1 (en) * | 2006-06-30 | 2016-07-27 | Sanofi | Cxcr2 inhibitors |
| DE602007009865D1 (de) * | 2006-11-23 | 2010-11-25 | Novartis Ag | 5-sulfanylmethylä1,2,4ütriazolä1,5-aüpyrimidin-7-olderivate als cxcr2-antagonisten |
| AU2007324472A1 (en) * | 2006-11-23 | 2008-05-29 | Novartis Ag | 5-sulfanylmethyl-pyrazolo [1,5-a] pyrimidin-7-ol derivatives as CXCR2 antagonists |
| US7705154B2 (en) * | 2006-11-30 | 2010-04-27 | Dow Agrosciences Llc | Process for the preparation of 2-substituted-5-(1-alkylthio)alkylpyridines |
| RU2477279C2 (ru) * | 2007-06-05 | 2013-03-10 | Санофи-Авентис | Замещенные бензоиламиноиндан-2-карбоновые кислоты и родственные соединения |
| NZ592741A (en) | 2008-11-14 | 2013-03-28 | Fibrogen Inc | Thiochromene derivatives as hif hydroxylase inhibitors |
| AU2013203591B2 (en) * | 2009-05-01 | 2017-01-19 | University Court Of The University Of Dundee | Treatment or prophylaxis of proliferative conditions |
| GB0907551D0 (en) * | 2009-05-01 | 2009-06-10 | Univ Dundee | Treatment or prophylaxis of proliferative conditions |
| WO2012079154A1 (en) * | 2010-12-14 | 2012-06-21 | Dalhousie University | Selective estrogen receptor modulators |
| MX2014014708A (es) * | 2012-06-19 | 2015-02-24 | Hoffmann La Roche | Nuevos compuestos biciclicos de tiofenilamida. |
| CN104619705B (zh) * | 2012-09-12 | 2018-01-02 | 霍夫曼-拉罗奇有限公司 | 作为脂肪酸结合蛋白(fabp)4和/或5的抑制剂的非成环噻吩基酰胺 |
| JP6437456B2 (ja) | 2013-01-24 | 2018-12-12 | フィブロジェン インコーポレイテッド | ｛［１−シアノ−５−（４−クロロフェノキシ）−４−ヒドロキシ−イソキノリン−３−カルボニル］−アミノ｝−酢酸の結晶形態 |
| WO2014114603A1 (en) * | 2013-01-24 | 2014-07-31 | F. Hoffmann-La Roche Ag | Substituted thiazole compounds |
| US9828399B2 (en) * | 2014-02-28 | 2017-11-28 | The Royal Institution For The Advancement Of Learning/Mcgill University | TC-PTP inhibitors as APC activators for immunotherapy |
| CA2944140C (en) * | 2014-04-15 | 2022-10-04 | Vertex Pharmaceuticals Incorporated | Pharmaceutical compositions for the treatment of cystic fibrosis transmembrane conductance regulator mediated diseases |
| RU2017106172A (ru) * | 2014-07-31 | 2018-08-28 | Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед | Применение антагонистов cxcr2 для предотвращения и/или лечения периферической невропатии, вызванной химиотерапией (cipn) |
| CN105906608B (zh) * | 2016-05-03 | 2018-10-19 | 中山大学 | 8-氨基喹啉-松果体素杂联体及其药物组合物 |
| CN106187974B (zh) * | 2016-07-01 | 2018-01-12 | 广州军区广州总医院 | 具有抗肿瘤作用的鱼藤素断环结构与氨基酸衍生物的合成方法 |
| PT3717646T (pt) | 2017-12-01 | 2025-07-28 | Texas A & M Univ Sys | Tratamento antisense da síndrome de angelman |
| AU2019216531A1 (en) | 2018-02-02 | 2020-09-24 | Maverix Oncology, Inc. | Small molecule drug conjugates of gemcitabine monophosphate |
| GB201807924D0 (en) * | 2018-05-16 | 2018-06-27 | Ctxt Pty Ltd | Compounds |
| PE20211275A1 (es) | 2018-07-09 | 2021-07-19 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos heterociclicos antihelminticos |
| KR20220002890A (ko) | 2019-03-19 | 2022-01-07 | 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 | 구충성 아자-벤조티오펜 및 아자-벤조푸란 화합물 |
| WO2021113806A1 (en) * | 2019-12-05 | 2021-06-10 | Genzyme Corporation | Arylamides and methods of use thereof |
| WO2021113808A1 (en) * | 2019-12-05 | 2021-06-10 | Genzyme Corporation | Cftr-modulating arylamides |
| JP7662644B2 (ja) | 2019-12-18 | 2025-04-15 | シーティーエックスティー・ピーティーワイ・リミテッド | 化合物 |
| MX2022015038A (es) | 2020-05-29 | 2023-01-04 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos heterociclicos como anthelminticos. |
| CN111559991B (zh) * | 2020-06-01 | 2022-01-25 | 河南省锐达医药科技有限公司 | 一种萘胺类化合物及其盐的制备方法和应用 |
| PE20250675A1 (es) | 2021-11-01 | 2025-03-04 | Boehringer Ingelheim Vetmedica Gmbh | Compuestos de pirrolopiridazina como antihelminticos |
| CN115385865B (zh) * | 2022-06-29 | 2023-06-16 | 深圳大学 | 一种具有cxcr2抑制活性的小分子抑制剂及其制备方法与应用 |
| CN116041300B (zh) * | 2023-02-20 | 2024-04-26 | 沈阳药科大学 | 一种2,2-二甲基苯并吡喃类衍生物及其制备方法和应用 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4962224A (en) * | 1987-12-23 | 1990-10-09 | American Home Products Corporation | N-naphthoylglycines as aldose reductase inhibitors |
| US4994477A (en) * | 1988-03-24 | 1991-02-19 | Abbott Laboratories | Heterocyclic renin inhibitors |
| US6531467B2 (en) * | 1996-09-12 | 2003-03-11 | Idun Pharmaceuticals, Inc. | Inhibition of inflammation using interleukin-1β-converting enzyme (ICE)/CED-3 family inhibitors |
| GB9716657D0 (en) * | 1997-08-07 | 1997-10-15 | Zeneca Ltd | Chemical compounds |
| IT1317826B1 (it) | 2000-02-11 | 2003-07-15 | Dompe Spa | Ammidi, utili nell'inibizione della chemiotassi dei neutrofiliindotta da il-8. |
| DE10006139A1 (de) * | 2000-02-11 | 2001-08-16 | Merck Patent Gmbh | Indol-3-yl-Derivate |
| FR2825706B1 (fr) * | 2001-06-06 | 2003-12-12 | Pf Medicament | Nouveaux derives de benzothienyle ou d'indole, leur preparation et leur utilisation comme inhibiteurs de proteines prenyl transferase |
| US6673791B2 (en) * | 2001-07-30 | 2004-01-06 | Boehringer Ingelheim (Canada) Ltd. | Non-nucleoside reverse transcriptase inhibitors |
| GB2389580A (en) * | 2002-06-12 | 2003-12-17 | Bayer Ag | 2-Naphthamide PGI2 antagonists |
| CN103145616B (zh) * | 2003-06-06 | 2015-09-30 | 菲布罗根有限公司 | 含氮杂芳基化合物及其在增加内源性促红细胞生成素中的用途 |
| JP2007501844A (ja) * | 2003-08-08 | 2007-02-01 | トランス テック ファーマ，インコーポレイテッド | アリール及びヘテロアリール化合物、組成物並びに使用方法 |
| WO2005023818A2 (en) | 2003-09-10 | 2005-03-17 | Gpc Biotech Ag | Heterobicyclic compounds as pharmaceutically active agents |
| US20050085531A1 (en) | 2003-10-03 | 2005-04-21 | Hodge Carl N. | Thiophene-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof |
| WO2005051940A2 (en) | 2003-11-20 | 2005-06-09 | Eli Lilly And Company | Vitamin d receptor modulators |
| GB0401334D0 (en) | 2004-01-21 | 2004-02-25 | Novartis Ag | Organic compounds |
| WO2006040646A1 (en) | 2004-10-14 | 2006-04-20 | Pfizer, Inc. | Benzimidazole or indole amides as inhibitors of pin1 |
| BRPI0517567A (pt) | 2004-11-09 | 2008-06-17 | Smithkline Beecham Corp | composto ou um sal, solvato, ou derivado fisiologicamente funcional farmaceuticamente aceitável do mesmo, composição farmacêutica, usos de um composto ou um sal, solvato, ou derivado fisiologicamente funcional farmaceuticamente aceitável do mesmo e de uma composição farmacêutica, e, processo para preparar um composto |
| EP1676834A1 (en) * | 2004-12-30 | 2006-07-05 | Sanofi-Aventis Deutschland GmbH | Fused bicyclic carboxamide derivates for use as CXCR2 inhibitors in the treatment of inflammation |
| AR055319A1 (es) | 2005-03-17 | 2007-08-15 | Wyeth Corp | Derivados de isoquinoleina, composiciones farmaceuticas y usos |
-
2004
- 2004-12-30 EP EP04031009A patent/EP1676834A1/en not_active Withdrawn
-
2005
- 2005-12-17 NZ NZ556192A patent/NZ556192A/en not_active IP Right Cessation
- 2005-12-17 KR KR1020077015119A patent/KR20070091634A/ko not_active Withdrawn
- 2005-12-17 MX MX2007007068A patent/MX2007007068A/es active IP Right Grant
- 2005-12-17 EP EP05818685A patent/EP1836158B1/en not_active Expired - Lifetime
- 2005-12-17 BR BRPI0519452-0A patent/BRPI0519452A2/pt not_active Application Discontinuation
- 2005-12-17 AT AT05818685T patent/ATE543795T1/de active
- 2005-12-17 JP JP2007548720A patent/JP5123667B2/ja not_active Expired - Fee Related
- 2005-12-17 CA CA002592430A patent/CA2592430A1/en not_active Withdrawn
- 2005-12-17 RU RU2007128949/04A patent/RU2404962C2/ru not_active IP Right Cessation
- 2005-12-17 AU AU2005321609A patent/AU2005321609B2/en not_active Ceased
- 2005-12-17 CN CNA2005800454624A patent/CN101094830A/zh active Pending
- 2005-12-17 WO PCT/EP2005/013624 patent/WO2006069656A1/en not_active Ceased
- 2005-12-28 TW TW094146875A patent/TW200639141A/zh unknown
- 2005-12-28 AR ARP050105577A patent/AR055830A1/es unknown
- 2005-12-30 UY UY29322A patent/UY29322A1/es unknown
-
2006
- 2006-01-03 PE PE2006000027A patent/PE20060855A1/es not_active Application Discontinuation
-
2007
- 2007-05-21 ZA ZA200704089A patent/ZA200704089B/xx unknown
- 2007-06-24 IL IL184173A patent/IL184173A/en unknown
- 2007-06-26 MA MA30032A patent/MA29113B1/fr unknown
- 2007-06-29 US US11/771,958 patent/US7919628B2/en not_active Expired - Fee Related
- 2007-07-26 NO NO20073932A patent/NO20073932L/no unknown
-
2011
- 2011-04-04 US US13/079,522 patent/US8283479B2/en not_active Expired - Fee Related
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