JP2008526188A5 - - Google Patents

Download PDF

Info

Publication number
JP2008526188A5
JP2008526188A5 JP2007548837A JP2007548837A JP2008526188A5 JP 2008526188 A5 JP2008526188 A5 JP 2008526188A5 JP 2007548837 A JP2007548837 A JP 2007548837A JP 2007548837 A JP2007548837 A JP 2007548837A JP 2008526188 A5 JP2008526188 A5 JP 2008526188A5
Authority
JP
Japan
Prior art keywords
use according
protein
promoter
nucleic acid
virus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2007548837A
Other languages
English (en)
Japanese (ja)
Other versions
JP5584393B2 (ja
JP2008526188A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2006/000009 external-priority patent/WO2006070023A2/en
Publication of JP2008526188A publication Critical patent/JP2008526188A/ja
Publication of JP2008526188A5 publication Critical patent/JP2008526188A5/ja
Application granted granted Critical
Publication of JP5584393B2 publication Critical patent/JP5584393B2/ja
Anticipated expiration legal-status Critical
Active legal-status Critical Current

Links

JP2007548837A 2004-12-31 2006-01-02 動物細胞における多剤耐性を逆転させる方法 Active JP5584393B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE102004063639.7 2004-12-31
DE102004063639 2004-12-31
US65108505P 2005-02-08 2005-02-08
US60/651,085 2005-02-08
PCT/EP2006/000009 WO2006070023A2 (en) 2004-12-31 2006-01-02 Method for reversing multiple resistance in animal cells

Publications (3)

Publication Number Publication Date
JP2008526188A JP2008526188A (ja) 2008-07-24
JP2008526188A5 true JP2008526188A5 (enExample) 2009-02-19
JP5584393B2 JP5584393B2 (ja) 2014-09-03

Family

ID=36582063

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007548837A Active JP5584393B2 (ja) 2004-12-31 2006-01-02 動物細胞における多剤耐性を逆転させる方法

Country Status (10)

Country Link
US (4) US20100310554A1 (enExample)
EP (1) EP1831382B1 (enExample)
JP (1) JP5584393B2 (enExample)
KR (1) KR101527213B1 (enExample)
CN (1) CN101128593B (enExample)
AU (1) AU2006203736B2 (enExample)
CA (1) CA2592699C (enExample)
MX (1) MX2007008136A (enExample)
SG (1) SG158133A1 (enExample)
WO (1) WO2006070023A2 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1655827B (zh) 2002-05-27 2010-06-23 佩尔·松内·霍尔姆 腺病毒和编码其的核酸的新应用
WO2005051430A1 (de) 2003-11-14 2005-06-09 Per Sonne Holm Neue verwendung von adenoviren und dafür codierenden nukleinsäuren
EP1830864A2 (de) * 2004-12-31 2007-09-12 Per Sonne Holm E1 -minus adenoviren und deren verwendung
WO2010068794A2 (en) 2008-12-10 2010-06-17 The General Hospital Corporation Hif inhibitors and use thereof
CN107982548A (zh) 2012-02-07 2018-05-04 全球生物疗法有限公司 核酸输送的区室化方法及其组合物和应用
CA2903582C (en) 2013-03-14 2021-06-08 Salk Institute For Biological Studies Oncolytic adenovirus compositions
EP3033414A4 (en) 2013-08-12 2017-03-22 Invivosciences Inc. Automated cell culture system and method
WO2017147265A1 (en) 2016-02-23 2017-08-31 Salk Institute For Biological Studies High throughput assay for measuring adenovirus replication kinetics
JP7015551B2 (ja) 2016-02-23 2022-02-15 ソーク インスティテュート フォー バイオロジカル スタディーズ ウイルス動態への影響を最小限にするための治療用アデノウイルスにおける外因性遺伝子発現
US10813957B2 (en) * 2016-10-07 2020-10-27 Miami University Engineered oncolytic viruses containing hyper-binding sites to sequester and suppress activity of oncogenic transcription factors as a novel treatment for human cancer
CA3045892A1 (en) 2016-12-12 2018-06-21 Salk Institute For Biological Studies Tumor-targeting synthetic adenoviruses and uses thereof
EP3610870A4 (en) * 2017-03-31 2020-12-09 Ogata, Hisanobu METHOD OF EXPANSION OF AN ONCOLYTIC VIRUS AND ANTI-TUMOR AGENT
EA201990822A1 (ru) 2017-04-12 2020-01-09 Эписентарикс, Инк. Иммуномодулирующие слитые белки
EP3630959A4 (en) * 2017-05-24 2021-03-17 EpicentRx, Inc. ANTI-ANGIOGENIC ADENOVIRUS
CN109576231B (zh) * 2017-09-28 2022-03-25 北京康万达医药科技有限公司 分离的重组溶瘤腺病毒、药物组合物及其在治疗肿瘤和/或癌症的药物中的用途
BR112020019942A2 (pt) 2018-04-09 2021-01-26 Salk Institute For Biological Studies composições de adenovírus oncolítico com propriedades de replicação aprimoradas
CN113774031B (zh) * 2020-06-10 2024-04-02 广州恩宝生物医药科技有限公司 一种复制型人腺病毒及其应用
CN118119703A (zh) * 2021-09-30 2024-05-31 富士胶片株式会社 腺相关病毒的制造方法、细胞及表达载体

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3827163B2 (ja) * 1995-03-24 2006-09-27 ジェンザイム・コーポレーション 遺伝子治療用のアデノウイルスベクター
AU2319497A (en) * 1996-03-07 1997-09-22 Regents Of The University Of California, The Helper-free, totally defective adenovirus for gene therapy
US6054467A (en) * 1996-07-05 2000-04-25 Sidney Kimmel Cancer Center Down-regulation of DNA repair to enhance sensitivity to P53-mediated apoptosis
DK1199368T3 (da) * 1998-07-07 2004-04-13 Transgene Sa Anvendelse af adenovirus-E4-læserammer til forbedring af ekspression af et gen af interesse
AU2145300A (en) * 1998-11-18 2000-06-05 Canji, Inc. Adenoviral vectors
US6764674B1 (en) * 1999-01-28 2004-07-20 Onyx Pharmaceuticals Inc. Adenovirus E1B shuttle vectors
DE19929569A1 (de) * 1999-06-21 2000-12-28 Holm Per Sonne Mittel zur Behandlung maligner Erkrankungen unter Verwendung des Proteins YB-1
AU6425800A (en) * 1999-06-30 2001-01-22 Max-Delbruck-Centrum Fur Molekulare Medizin Agents for the diagnosis, prognosis and treatment of malignant diseases
US6955808B2 (en) * 1999-09-24 2005-10-18 Uab Research Foundation Capsid-modified recombinant adenovirus and methods of use
US6635476B1 (en) * 1999-10-15 2003-10-21 Canji, Inc. Targeted vectors
US7048920B2 (en) * 2000-03-24 2006-05-23 Cell Genesys, Inc. Recombinant oncolytic adenovirus for human melanoma
US20030095989A1 (en) * 2000-12-18 2003-05-22 Irving John M. Chimeric cytolytic viruses for cancer treatment
AU2002343901A1 (en) * 2001-09-29 2003-04-14 Kim, Joo-Hang Recombinant adenovirus with enhanced therapeutic effect and pharmaceutical composition comprising said recombinant adenovirus
DE10150984A1 (de) * 2001-10-16 2003-04-17 Holm Per Sonne Verwendung des adenoviralen E2-late-Promotors
WO2004001032A2 (en) * 2002-04-25 2003-12-31 Crucell Holland B.V. Stable adenoviral vectors and methods for propagation thereof
CN1655827B (zh) * 2002-05-27 2010-06-23 佩尔·松内·霍尔姆 腺病毒和编码其的核酸的新应用
JP4988199B2 (ja) * 2002-10-15 2012-08-01 ホルム,ペル・ゾンネ 新規アデノウイルス、それをコードする核酸及びその使用
US8951772B2 (en) * 2002-10-15 2015-02-10 Per Sonne Holm Adenoviruses, nucleic acids coding therefor, and use thereof
CA2522380A1 (en) * 2003-03-19 2004-09-30 Isogenis, Inc. Specific inhibition of allorejection
JP4871726B2 (ja) * 2003-04-28 2012-02-08 ナノシス・インク. 超疎液性表面、その作製法及び用途
WO2005051430A1 (de) * 2003-11-14 2005-06-09 Per Sonne Holm Neue verwendung von adenoviren und dafür codierenden nukleinsäuren
US20060270016A1 (en) * 2003-11-14 2006-11-30 Holm Per S Novel adenoviruses, nucleic acids that code for the same and the use of said viruses
EP1830864A2 (de) 2004-12-31 2007-09-12 Per Sonne Holm E1 -minus adenoviren und deren verwendung
US20070292396A1 (en) * 2006-03-02 2007-12-20 Juan Fueyo Combination therapy with oncolytic adenovirus

Similar Documents

Publication Publication Date Title
JP2008526188A5 (enExample)
US11268073B2 (en) Use of adenovirus and nucleic acids coding therefor
Dash et al. mda-7/IL-24: a unique member of the IL-10 gene family promoting cancer-targeted toxicity
KR101396454B1 (ko) 내피 세포 특이성을 나타내는 프로모터 및 이를 이용하여 혈관신생을 조절하는 방법
Zhu et al. Oncolytic adenovirus armed with IL-24 inhibits the growth of breast cancer in vitro and in vivo
US20100311145A1 (en) Novel use of adenoviruses and nucleic acids that code for said viruses
KR102229084B1 (ko) 아데노바이러스를 사용하는 치료 방법
US20100151576A1 (en) Targeted tumor therapy by use of recombinant adenovirus vectors that selectively replicate in hypoxic regions of tumors
JP2007511212A5 (enExample)
JP2004500880A (ja) 肝臓特異的な遺伝子発現カセット、及びその使用法
JP2011200234A (ja) 新規アデノウイルス、それをコードする核酸及びその使用
JP2008526189A5 (enExample)
JP2006512284A5 (enExample)
JP5435871B2 (ja) E1−マイナスアデノウイルス及びその使用
JP5584393B2 (ja) 動物細胞における多剤耐性を逆転させる方法
US20040242523A1 (en) Chemo-inducible cancer gene therapy
WO2012022496A2 (en) Method for killing tumor stem cells
RU2005114516A (ru) Аденовирус с обращенной генной экспрессией и его применение
Hodish et al. Systemic administration of radiation-potentiated anti-angiogenic gene therapy against primary and metastatic cancer based on transcriptionally controlled HSV-TK
AU2015201828B2 (en) Novel use of adenoviruses and nucleic acids coding therefor
CN1705740B (zh) 具有反向基因表达的腺病毒及其应用
Parikh et al. 294. Herpes Simplex Virus Mediated Oncolysis is an Effective Intratumoral Therapy in High-Risk Neuroblastoma Tumor Models
RU2004138095A (ru) Новое применение аденовируса и кодирующих его нуклеиновых кислот