JP2008525513A5 - - Google Patents

Download PDF

Info

Publication number
JP2008525513A5
JP2008525513A5 JP2007548747A JP2007548747A JP2008525513A5 JP 2008525513 A5 JP2008525513 A5 JP 2008525513A5 JP 2007548747 A JP2007548747 A JP 2007548747A JP 2007548747 A JP2007548747 A JP 2007548747A JP 2008525513 A5 JP2008525513 A5 JP 2008525513A5
Authority
JP
Japan
Prior art keywords
substituted
unsubstituted
compound
formula
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007548747A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008525513A (ja
Filing date
Publication date
Priority claimed from EP04380279A external-priority patent/EP1676844A1/en
Application filed filed Critical
Publication of JP2008525513A publication Critical patent/JP2008525513A/ja
Publication of JP2008525513A5 publication Critical patent/JP2008525513A5/ja
Pending legal-status Critical Current

Links

JP2007548747A 2004-12-28 2005-12-27 5−ht7受容体拮抗薬 Pending JP2008525513A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04380279A EP1676844A1 (en) 2004-12-28 2004-12-28 5-HT7 receptor antagonists
US11/048,992 US7345057B2 (en) 2004-12-28 2005-02-02 5-HT7 receptor antagonists
PCT/EP2005/014046 WO2006069776A1 (en) 2004-12-28 2005-12-27 5-ht7 receptor antagonists

Publications (2)

Publication Number Publication Date
JP2008525513A JP2008525513A (ja) 2008-07-17
JP2008525513A5 true JP2008525513A5 (OSRAM) 2009-02-12

Family

ID=34931894

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007548747A Pending JP2008525513A (ja) 2004-12-28 2005-12-27 5−ht7受容体拮抗薬

Country Status (11)

Country Link
US (1) US7345057B2 (OSRAM)
EP (2) EP1676844A1 (OSRAM)
JP (1) JP2008525513A (OSRAM)
KR (1) KR20070091040A (OSRAM)
CN (1) CN101090898A (OSRAM)
AU (1) AU2005321463A1 (OSRAM)
BR (1) BRPI0519792A2 (OSRAM)
CA (1) CA2590666A1 (OSRAM)
MX (1) MX2007007894A (OSRAM)
RU (1) RU2007128926A (OSRAM)
WO (1) WO2006069776A1 (OSRAM)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103880827B (zh) 2004-07-15 2017-01-04 阿尔巴尼分子研究公司 芳基和杂芳基取代的四氢异喹啉及其阻断去甲肾上腺素、多巴胺和血清素的重摄取的应用
US8507523B2 (en) * 2006-11-21 2013-08-13 Renukadevi Patil Therapeutic tetrahydroisoquinoline-based compositions for cancer therapy
US8202873B2 (en) * 2007-05-11 2012-06-19 Eli Lilly And Company 2-[4-(pyrazol-4-ylalkyl)piperazin-1-yl]-3-phenyl pyrazines as 5-HT7 receptor antagonists
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
WO2010080864A1 (en) 2009-01-12 2010-07-15 Array Biopharma Inc. Piperidine-containing compounds and use thereof
KR101830447B1 (ko) * 2009-05-12 2018-02-20 알바니 몰레큘라 리써치, 인크. 7-([1,2,4]트리아졸로[1,5-α]피리딘-6-일)-4-(3,4-디클로로페닐)-1,2,3,4-테트라하이드로이소퀴놀린 및 이의 용도
US8815894B2 (en) * 2009-05-12 2014-08-26 Bristol-Myers Squibb Company Crystalline forms of (S)-7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline and use thereof
EP2429295B1 (en) 2009-05-12 2013-12-25 Albany Molecular Research, Inc. Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof
GB201209587D0 (en) 2012-05-30 2012-07-11 Takeda Pharmaceutical Therapeutic compounds
EA029430B1 (ru) * 2013-06-21 2018-03-30 Такеда Фармасьютикл Компани Лимитед Производные 1-сульфонилпиперидина в качестве модуляторов рецепторов прокинетицина
GB201420095D0 (en) 2014-11-12 2014-12-24 Takeda Pharmaceutical New use
EP3589626B1 (en) * 2017-03-03 2024-06-12 National Taiwan University 8-phenyl-isoquinolines and pharmaceutical composition thereof used in the treatment of irritable bowel syndrome
US10357493B2 (en) 2017-03-10 2019-07-23 Selenity Therapeutics (Bermuda), Ltd. Metalloenzyme inhibitor compounds
CN112083107B (zh) * 2020-09-28 2022-07-05 中国计量科学研究院 检测蜂蜜基质中磺胺类药物葡萄糖醛酸结合物的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ193654A (en) 1979-05-16 1984-08-24 Wuelfing Johann A Naphthalene sulphonamido-alkyl-piperidines,pyrrolidines or piperazines and pharmaceutical compositions
EP0076072B1 (en) 1981-09-24 1987-05-13 BEECHAM - WUELFING GmbH & Co. KG Sulphonamides
WO1997029097A1 (en) 1996-02-09 1997-08-14 Smithkline Beecham Plc Sulfonamide derivatives as 5ht7 receptor antagonists
GB9612884D0 (en) 1996-06-20 1996-08-21 Smithkline Beecham Plc Novel compounds
WO1997049695A1 (en) * 1996-06-25 1997-12-31 Smithkline Beecham P.L.C. Sulfonamide derivatives as 5ht7 receptor antagonists
WO1999024022A2 (en) 1997-11-10 1999-05-20 F. Hoffmann-La Roche Ag Isoquinoline derivatives for treating disorders associated with 5ht7 receptors
AU4698299A (en) * 1998-06-30 2000-01-17 Du Pont Pharmaceuticals Company 5-HT7 receptor antagonists
GB0128885D0 (en) 2001-12-03 2002-01-23 Merck Sharp & Dohme Therapeutic agents

Similar Documents

Publication Publication Date Title
JP2008525513A5 (OSRAM)
JP2010520869A5 (OSRAM)
JP2008133297A5 (OSRAM)
WO2010129467A1 (en) Compounds and methods for inhibition of renin, and indications therefor
KR20060027338A (ko) 벤즈 아미드 유도체 또는 그 염
JPWO2012102254A1 (ja) インドール誘導体、またはその薬理学的に許容される塩
JP2009538358A (ja) 脂肪酸アミド加水分解酵素のオキサゾリルピペリジン・モジュレーター
JP2008505107A5 (OSRAM)
JP2015178458A (ja) ベンゼン環縮合含窒素5員複素環式化合物、またはその薬理学的に許容される塩
JP2007015928A (ja) 新規オレフィン誘導体
CA2570197A1 (en) Nk1 antagonists
RU2582337C2 (ru) Производные триазола в качестве лигандов рецепторов гамк
JP2010504351A5 (OSRAM)
US7671056B2 (en) Piperazine-piperidine antagonists and agonists of the 5-HT1A receptor
JP2004507527A5 (OSRAM)
WO2011013624A1 (ja) インドール誘導体、またはその薬理学的に許容される塩
JP2007530648A (ja) Cns障害の処置のための、5−ht6受容体アンタゴニストとしての3−((ヘテロ)アリールスルフォニル)−8−((アミノアルキル)オキシ)キノリン
JP6943239B2 (ja) Kcnq2〜5チャネル活性化剤
JP2005528367A5 (OSRAM)
JP2008525512A5 (OSRAM)
CA2720461C (en) Classes of gabaa/bzr ligands
JP3887785B2 (ja) 5−ht2レセプター親和性を有する置換四環状オキサゼピン及びチアゼピン誘導体
JPWO2006132438A1 (ja) 1,3−ベンゾチアジノン誘導体およびその用途
JP2006523223A5 (OSRAM)
JP4042566B2 (ja) ピペリジン化合物およびその医薬用途