|
US9492400B2
(en)
|
2004-11-04 |
2016-11-15 |
Massachusetts Institute Of Technology |
Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals
|
|
WO2006066158A2
(en)
*
|
2004-12-14 |
2006-06-22 |
Alnylam Pharmaceuticals, Inc. |
Rnai modulation of mll-af4 and uses thereof
|
|
JP5489459B2
(ja)
*
|
2005-08-01 |
2014-05-14 |
ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション |
乳癌の診断、予後及び治療のためのマイクロrnaに基づいた方法及び組成物
|
|
CA2845251A1
(en)
*
|
2005-09-12 |
2007-03-22 |
The Ohio State University Research Foundation |
Compositions for the therapy of bcl2-associated cancers and methods of preparation thereof
|
|
US20090270484A1
(en)
*
|
2005-10-05 |
2009-10-29 |
The Ohio State University Research Foundation |
WWOX Vectors and Uses in Treatment of Cancer
|
|
US9267937B2
(en)
|
2005-12-15 |
2016-02-23 |
Massachusetts Institute Of Technology |
System for screening particles
|
|
EP2487258B1
(en)
|
2006-01-05 |
2014-10-01 |
The Ohio State University Research Foundation |
MicroRNA-based methods for the diagnosis of colon, pancreas and stomach cancer
|
|
JP5490413B2
(ja)
|
2006-01-05 |
2014-05-14 |
ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション |
膵内分泌腫瘍及び膵腺房腫瘍におけるマイクロrna発現異常
|
|
CN102943108B
(zh)
|
2006-01-05 |
2014-05-21 |
俄亥俄州立大学研究基金会 |
用于肺癌的诊断、预后和治疗的基于微小rna的方法和组合物
|
|
ES2446362T3
(es)
|
2006-03-20 |
2014-03-07 |
The Ohio State University Research Foundation |
Huellas de microARN durante megacariocipoyesis humana
|
|
US8367113B2
(en)
|
2006-05-15 |
2013-02-05 |
Massachusetts Institute Of Technology |
Polymers for functional particles
|
|
WO2007150030A2
(en)
|
2006-06-23 |
2007-12-27 |
Massachusetts Institute Of Technology |
Microfluidic synthesis of organic nanoparticles
|
|
CA2657030A1
(en)
|
2006-07-13 |
2008-01-17 |
The Ohio State University Research Foundation, An Instrumentality Of The State Of Ohio |
Micro-rna-based methods and compositions for the diagnosis and treatment of colon cancer-related diseases
|
|
CN101535505A
(zh)
|
2006-09-19 |
2009-09-16 |
俄亥俄州立大学研究基金会 |
慢性淋巴细胞性白血病(CLL)中受miR-29和miR-181调控的TCL1的表达
|
|
EP2087135B8
(en)
|
2006-11-01 |
2013-07-24 |
The Ohio State University Research Foundation |
Microrna expression signature for predicting survival and metastases in hepatocellular carcinoma
|
|
CN105256004A
(zh)
*
|
2007-01-31 |
2016-01-20 |
俄亥俄州立大学研究基金会 |
用于急性髓细胞白血病(aml)的诊断、预后和治疗的基于微rna的方法和组合物
|
|
US9217129B2
(en)
|
2007-02-09 |
2015-12-22 |
Massachusetts Institute Of Technology |
Oscillating cell culture bioreactor
|
|
EP2136788B1
(en)
|
2007-03-30 |
2011-10-26 |
Bind Biosciences, Inc. |
Cancer cell targeting using nanoparticles
|
|
WO2008124632A1
(en)
|
2007-04-04 |
2008-10-16 |
Massachusetts Institute Of Technology |
Amphiphilic compound assisted nanoparticles for targeted delivery
|
|
CA2685840C
(en)
*
|
2007-04-30 |
2016-12-13 |
The Ohio State University Research Foundation |
Methods for differentiating pancreatic cancer from normal pancreatic function and/or chronic pancreatitis
|
|
ES2527648T3
(es)
*
|
2007-06-08 |
2015-01-28 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Métodos para determinar el subtipo de carcinoma hepatocelular
|
|
AR066984A1
(es)
*
|
2007-06-15 |
2009-09-23 |
Novartis Ag |
Inhibicion de la expresion de la subunidad alfa del canal epitelial de sodio (enac) por medio de arni (arn de interferencia)
|
|
EP2719773A3
(en)
|
2007-06-15 |
2014-07-30 |
The Ohio State University Research Foundation |
miRNA as marker for acute lamphomic leucemia
|
|
ES2496172T3
(es)
*
|
2007-07-31 |
2014-09-18 |
The Ohio State University Research Foundation |
Métodos para invertir la metilación por selección dirigida de DNMT3A y DNMT3B
|
|
JP2010535473A
(ja)
|
2007-08-03 |
2010-11-25 |
ズィ、オハイオウ、ステイト、ユーニヴァーサティ、リサーチ、ファウンデイシャン |
ncRNAをコードする超保存領域
|
|
CA2696887C
(en)
*
|
2007-08-22 |
2016-06-28 |
The Ohio State University Research Foundation |
Methods and compositions for inducing deregulation of epha7 and erk phosphorylation in human acute leukemias
|
|
KR20100065190A
(ko)
|
2007-09-14 |
2010-06-15 |
닛토덴코 가부시키가이샤 |
약물 담체
|
|
EP2630966B1
(en)
|
2007-10-12 |
2017-04-19 |
Massachusetts Institute of Technology |
Vaccine nanotechnology
|
|
CN102137927B
(zh)
|
2007-10-26 |
2014-03-12 |
俄亥俄州立大学研究基金会 |
鉴定脆性组氨酸三联体(Fhit)相互作用的方法及其用途
|
|
JP2011505143A
(ja)
*
|
2007-11-30 |
2011-02-24 |
ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション |
マイクロrna発現プロファイリング及び肺癌における末梢血ターゲティング
|
|
US8188060B2
(en)
|
2008-02-11 |
2012-05-29 |
Dharmacon, Inc. |
Duplex oligonucleotides with enhanced functionality in gene regulation
|
|
AU2009219193A1
(en)
*
|
2008-02-28 |
2009-09-03 |
The Ohio State University Research Foundation |
MicroRNA signatures associated with human chronic lymphocytic leukemia (CCL) and uses thereof
|
|
US20110054009A1
(en)
*
|
2008-02-28 |
2011-03-03 |
The Ohio State University Research Foundation |
MicroRNA-Based Methods and Compositions for the Diagnosis, Prognosis and Treatment of Prostate Related Disorders
|
|
ES2433940T3
(es)
|
2008-06-11 |
2013-12-13 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Uso de la familia miR-26 como marcador predictivo del carcinoma hepatocelular y sensibilidad a la terapia
|
|
WO2010023544A1
(en)
*
|
2008-08-28 |
2010-03-04 |
Council Of Scientific & Industrial Research |
Compositions and methods for delivery of protein-coding rnas to correct mitochondrial dysfunction
|
|
US8343498B2
(en)
|
2008-10-12 |
2013-01-01 |
Massachusetts Institute Of Technology |
Adjuvant incorporation in immunonanotherapeutics
|
|
US8591905B2
(en)
|
2008-10-12 |
2013-11-26 |
The Brigham And Women's Hospital, Inc. |
Nicotine immunonanotherapeutics
|
|
US8277812B2
(en)
|
2008-10-12 |
2012-10-02 |
Massachusetts Institute Of Technology |
Immunonanotherapeutics that provide IgG humoral response without T-cell antigen
|
|
US8343497B2
(en)
|
2008-10-12 |
2013-01-01 |
The Brigham And Women's Hospital, Inc. |
Targeting of antigen presenting cells with immunonanotherapeutics
|
|
CA2762653A1
(en)
|
2009-05-27 |
2010-12-02 |
Selecta Biosciences, Inc. |
Immunomodulatory agent-polymeric compounds
|
|
ES2804764T3
(es)
|
2009-06-01 |
2021-02-09 |
Halo Bio Rnai Therapeutics Inc |
Polinucleótidos para la interferencia de ARN multivalente, composiciones y métodos de uso de los mismos
|
|
EP3284494A1
(en)
|
2009-07-30 |
2018-02-21 |
Tandem Diabetes Care, Inc. |
Portable infusion pump system
|
|
US8916533B2
(en)
|
2009-11-23 |
2014-12-23 |
The Ohio State University |
Materials and methods useful for affecting tumor cell growth, migration and invasion
|
|
US8349308B2
(en)
|
2010-03-26 |
2013-01-08 |
Mersana Therapeutics, Inc. |
Modified polymers for delivery of polynucleotides, method of manufacture, and methods of use thereof
|
|
AU2011258165B2
(en)
|
2010-05-26 |
2016-11-17 |
Selecta Biosciences, Inc. |
Dose selection of adjuvanted synthetic nanocarriers
|
|
JP5931897B2
(ja)
|
2010-11-12 |
2016-06-08 |
ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイションThe Ohio State University Research Foundation |
マイクロrna−21、ミスマッチ修復および結腸直腸癌に関連する物質および方法
|
|
CA2817982C
(en)
|
2010-11-15 |
2020-06-30 |
The Regents Of The University Of Michigan |
Controlled release mucoadhesive systems
|
|
WO2012082894A1
(en)
*
|
2010-12-17 |
2012-06-21 |
Arrowhead Research Corporation |
Compositions and methods for inhibiting expression of mll genes
|
|
WO2012122239A1
(en)
|
2011-03-07 |
2012-09-13 |
The Ohio State University |
MUTATOR ACTIVITY INDUCED BY MICRORNA-155 (miR-155) LINKS INFLAMMATION AND CANCER
|
|
JP2014521687A
(ja)
|
2011-07-29 |
2014-08-28 |
セレクタ バイオサイエンシーズ インコーポレーテッド |
体液性および細胞傷害性tリンパ球(ctl)免疫応答を生成する合成ナノキャリア
|
|
AU2012323924A1
(en)
|
2011-10-14 |
2014-05-29 |
The Ohio State University |
Methods and materials related to ovarian cancer
|
|
CA2859430A1
(en)
|
2011-12-13 |
2013-06-20 |
Ohio State Innovation Foundation |
Methods and compositions related to mir-21 and mir-29a, exosome inhibition, and cancer metastasis
|
|
US8859202B2
(en)
|
2012-01-20 |
2014-10-14 |
The Ohio State University |
Breast cancer biomarker signatures for invasiveness and prognosis
|
|
US9180242B2
(en)
|
2012-05-17 |
2015-11-10 |
Tandem Diabetes Care, Inc. |
Methods and devices for multiple fluid transfer
|
|
US9173998B2
(en)
|
2013-03-14 |
2015-11-03 |
Tandem Diabetes Care, Inc. |
System and method for detecting occlusions in an infusion pump
|
|
JP2018525037A
(ja)
|
2015-08-24 |
2018-09-06 |
ハロー−バイオ・アールエヌエーアイ・セラピューティックス、インコーポレイテッド |
遺伝子発現の調節のためのポリヌクレオチドナノ粒子及びその使用
|
|
TN2019000308A1
(en)
|
2017-07-06 |
2021-05-07 |
Arrowhead Pharmaceuticals Inc |
RNAi AGENTS FOR INHIBITING EXPRESSION OF ALPHA-ENaC AND METHODS OF USE
|
|
CN107964536B
(zh)
*
|
2018-01-19 |
2021-10-22 |
上海交通大学医学院附属瑞金医院 |
一种实现人的诱导多能干细胞来源的造血干祖细胞强效体内移植的方法
|
|
AU2022366987A1
(en)
|
2021-10-14 |
2024-05-16 |
Arsenal Biosciences, Inc. |
Immune cells having co-expressed shrnas and logic gate systems
|
|
KR20250068649A
(ko)
|
2022-09-13 |
2025-05-16 |
아스널 바이오사이언시스, 인크. |
공동 발현된 tgfbr shrna를 갖는 면역 세포
|
|
EP4587570A2
(en)
|
2022-09-16 |
2025-07-23 |
Arsenal Biosciences, Inc. |
Immune cells with combination gene perturbations
|
|
KR20250158048A
(ko)
|
2023-03-03 |
2025-11-05 |
아스널 바이오사이언시스, 인크. |
Psma 및 ca9을 표적으로 하는 시스템
|
|
WO2025199338A1
(en)
|
2024-03-20 |
2025-09-25 |
Arsenal Biosciences, Inc. |
Systems targeting slc34a2 and tmprss4 and methods of use thereof
|