JP2025512771A5 - - Google Patents

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Publication number
JP2025512771A5
JP2025512771A5 JP2024555941A JP2024555941A JP2025512771A5 JP 2025512771 A5 JP2025512771 A5 JP 2025512771A5 JP 2024555941 A JP2024555941 A JP 2024555941A JP 2024555941 A JP2024555941 A JP 2024555941A JP 2025512771 A5 JP2025512771 A5 JP 2025512771A5
Authority
JP
Japan
Prior art keywords
rnai construct
construct according
antisense strand
sense strand
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024555941A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025512771A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/064765 external-priority patent/WO2023183801A2/en
Publication of JP2025512771A publication Critical patent/JP2025512771A/ja
Publication of JP2025512771A5 publication Critical patent/JP2025512771A5/ja
Pending legal-status Critical Current

Links

JP2024555941A 2022-03-23 2023-03-21 PNPLA3発現を阻害するためのRNAiコンストラクト及びその使用方法 Pending JP2025512771A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263322845P 2022-03-23 2022-03-23
US63/322,845 2022-03-23
PCT/US2023/064765 WO2023183801A2 (en) 2022-03-23 2023-03-21 Rnai constructs for inhibiting pnpla3 expression and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2025512771A JP2025512771A (ja) 2025-04-22
JP2025512771A5 true JP2025512771A5 (https=) 2026-03-30

Family

ID=88102183

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024555941A Pending JP2025512771A (ja) 2022-03-23 2023-03-21 PNPLA3発現を阻害するためのRNAiコンストラクト及びその使用方法

Country Status (13)

Country Link
US (1) US20250207138A1 (https=)
EP (1) EP4496893A2 (https=)
JP (1) JP2025512771A (https=)
KR (1) KR20240162559A (https=)
CN (1) CN118891364A (https=)
AR (1) AR128877A1 (https=)
AU (1) AU2023237880A1 (https=)
CA (1) CA3254112A1 (https=)
CL (1) CL2024002802A1 (https=)
IL (1) IL315078A (https=)
MX (1) MX2024011595A (https=)
TW (1) TW202345869A (https=)
WO (1) WO2023183801A2 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025252063A1 (zh) * 2024-06-04 2025-12-11 正大天晴药业集团股份有限公司 靶向pnpla3的双链核糖核酸

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2976445A1 (en) * 2015-02-13 2016-08-18 Alnylam Pharmaceuticals, Inc. Patatin-like phospholipase domain containing 3 (pnpla3) irna compositions and methods of use thereof
TW202542311A (zh) * 2018-09-19 2025-11-01 美商Ionis製藥公司 Pnpla3表現之調節劑

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