JP2008523140A5 - - Google Patents
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- Publication number
- JP2008523140A5 JP2008523140A5 JP2007546603A JP2007546603A JP2008523140A5 JP 2008523140 A5 JP2008523140 A5 JP 2008523140A5 JP 2007546603 A JP2007546603 A JP 2007546603A JP 2007546603 A JP2007546603 A JP 2007546603A JP 2008523140 A5 JP2008523140 A5 JP 2008523140A5
- Authority
- JP
- Japan
- Prior art keywords
- separation matrix
- matrix according
- particles
- binding protein
- ligand
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000011159 matrix material Substances 0.000 claims 12
- 238000000926 separation method Methods 0.000 claims 11
- 239000002245 particle Substances 0.000 claims 6
- 239000003446 ligand Substances 0.000 claims 4
- 102000014914 Carrier Proteins Human genes 0.000 claims 3
- 108091008324 binding proteins Proteins 0.000 claims 3
- 229920002307 Dextran Polymers 0.000 claims 2
- 150000001720 carbohydrates Chemical class 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- 229920000936 Agarose Polymers 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 238000005192 partition Methods 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0403057-3 | 2004-12-14 | ||
| SE0403057A SE0403057D0 (sv) | 2004-12-14 | 2004-12-14 | Purification of immunoglobulins |
| US63831604P | 2004-12-22 | 2004-12-22 | |
| US60/638,316 | 2004-12-22 | ||
| PCT/SE2005/001900 WO2006065208A1 (en) | 2004-12-14 | 2005-12-12 | Purification of immunoglobulins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008523140A JP2008523140A (ja) | 2008-07-03 |
| JP2008523140A5 true JP2008523140A5 (enExample) | 2008-12-11 |
| JP5787461B2 JP5787461B2 (ja) | 2015-09-30 |
Family
ID=36588164
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007546603A Expired - Lifetime JP5787461B2 (ja) | 2004-12-14 | 2005-12-12 | 免疫グロブリンの精製方法 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1830947A4 (enExample) |
| JP (1) | JP5787461B2 (enExample) |
| AU (1) | AU2005317279C1 (enExample) |
| CA (1) | CA2586803C (enExample) |
| WO (1) | WO2006065208A1 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5620626B2 (ja) | 2005-03-31 | 2014-11-05 | 中外製薬株式会社 | 会合制御によるポリペプチド製造方法 |
| DK2006381T3 (en) | 2006-03-31 | 2016-02-22 | Chugai Pharmaceutical Co Ltd | PROCEDURE FOR REGULATING ANTIBODIES BLOOD PHARMACOKINETICS |
| EP2009101B1 (en) | 2006-03-31 | 2017-10-25 | Chugai Seiyaku Kabushiki Kaisha | Antibody modification method for purifying bispecific antibody |
| JP5345539B2 (ja) * | 2006-09-29 | 2013-11-20 | ジーイー・ヘルスケア・バイオ−サイエンシズ・アーベー | 抗体単離のためのスタフィロコッカスアウレウス由来のドメインcを含むクロマトグラフィーリガンド |
| SG149759A1 (en) * | 2007-07-10 | 2009-02-27 | Millipore Corp | Media for affinity chromatography |
| ES2687808T3 (es) | 2007-09-26 | 2018-10-29 | Chugai Seiyaku Kabushiki Kaisha | Región constante de anticuerpo modificado |
| DK2202245T3 (en) | 2007-09-26 | 2016-11-21 | Chugai Pharmaceutical Co Ltd | A method of modifying an antibody isoelectric point VIA amino acid substitution in CDR |
| US8277649B2 (en) * | 2009-12-14 | 2012-10-02 | General Electric Company | Membranes and associated methods for purification of antibodies |
| EP2543730B1 (en) | 2010-03-04 | 2018-10-31 | Chugai Seiyaku Kabushiki Kaisha | Antibody constant region variant |
| CA2791918C (en) | 2010-03-05 | 2019-11-19 | Boehringer Ingelheim International Gmbh | Selective enrichment of antibodies |
| CN102388061A (zh) * | 2010-03-17 | 2012-03-21 | 松下电器产业株式会社 | 将由a蛋白或a蛋白的a至e结构域中的至少一个结构域所组成的蛋白质结合到基材上的方法 |
| US8859294B2 (en) | 2010-03-17 | 2014-10-14 | Panasonic Corporation | Method for binding a protein consisting of protein A or consisting of at least one domain of the A to E domains of the protein A to the substrate |
| US9090665B2 (en) | 2010-03-31 | 2015-07-28 | Jsr Corporation | Filler for affinity chromatography |
| JP5998050B2 (ja) | 2010-03-31 | 2016-09-28 | Jsr株式会社 | アフィニティークロマトグラフィー用充填剤 |
| TR201802772T4 (tr) | 2010-11-17 | 2018-03-21 | Chugai Pharmaceutical Co Ltd | Kan pıhtılaşma faktörü VIII in işlevi için alternatif işleve sahip multi-spesifik antijen bağlayıcı molekül. |
| LT2647707T (lt) | 2010-11-30 | 2018-11-12 | Chugai Seiyaku Kabushiki Kaisha | Citotoksiškumą indukuojantis terapinis agentas |
| WO2015030094A1 (ja) | 2013-08-30 | 2015-03-05 | 株式会社カネカ | Fab領域結合性ペプチド |
| WO2015035076A1 (en) * | 2013-09-04 | 2015-03-12 | Sten Ohlson | Weak affinity chromatography |
| JP6230853B2 (ja) * | 2013-09-06 | 2017-11-15 | 株式会社日立製作所 | タンパク質の精製方法及び精製装置 |
| ES2881306T3 (es) | 2013-09-27 | 2021-11-29 | Chugai Pharmaceutical Co Ltd | Método para la producción de heteromultímeros de polipéptidos |
| US20170043320A1 (en) | 2013-11-27 | 2017-02-16 | Jsr Corporation | Solid-phase carrier, production method for solid-phase carrier, carrier for affinity refining, production method for filler for affinity chromatography, filler for affinity chromatography, chromatography column, and refining method |
| EP3094391B1 (en) | 2014-01-17 | 2024-11-20 | Repligen Corporation | Sterilizing chromatography columns |
| CN119751653A (zh) | 2014-06-24 | 2025-04-04 | 思拓凡生物工艺研发有限公司 | 层析方法 |
| KR102410991B1 (ko) | 2014-06-27 | 2022-06-17 | 제이에스알 가부시끼가이샤 | 친화성 크로마토그래피용 담체 |
| US20170334947A1 (en) * | 2014-08-28 | 2017-11-23 | Kaneka Corporation | Affinity separation matrix for fab region-containing peptide |
| JPWO2016121701A1 (ja) | 2015-01-26 | 2017-11-09 | 株式会社カネカ | 免疫グロブリンκ鎖可変領域含有タンパク質精製用アフィニティー分離マトリックス |
| JP6663360B2 (ja) | 2015-01-26 | 2020-03-11 | 株式会社カネカ | 変異型免疫グロブリンκ鎖可変領域結合性ペプチド |
| WO2016159213A1 (ja) | 2015-04-01 | 2016-10-06 | 中外製薬株式会社 | ポリペプチド異種多量体の製造方法 |
| JP7219005B2 (ja) * | 2015-12-28 | 2023-02-07 | 中外製薬株式会社 | Fc領域含有ポリペプチドの精製を効率化するための方法 |
| JP7320943B2 (ja) | 2016-04-28 | 2023-08-04 | 中外製薬株式会社 | 抗体含有製剤 |
| WO2017195638A1 (ja) | 2016-05-09 | 2017-11-16 | 株式会社カネカ | 抗体またはκ鎖可変領域含有抗体断片の精製方法 |
| WO2017195641A1 (ja) * | 2016-05-11 | 2017-11-16 | 株式会社カネカ | アフィニティ分離マトリックスの製造方法およびアフィニティ分離マトリックス |
| GB201703116D0 (en) * | 2017-02-27 | 2017-04-12 | Ge Healthcare Bioprocess R&D Ab | A seperation matrix and a method of seperating antibodies |
| AU2018361430B2 (en) | 2017-11-01 | 2025-08-14 | Chugai Seiyaku Kabushiki Kaisha | Antibody variant and isoform with lowered biological activity |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4444879A (en) * | 1981-01-29 | 1984-04-24 | Science Research Center, Inc. | Immunoassay with article having support film and immunological counterpart of analyte |
| US5089605A (en) * | 1987-03-13 | 1992-02-18 | Repligen Corporation | Immobilized immunoglobulin-binding proteins |
| US5445732A (en) * | 1992-06-19 | 1995-08-29 | Sepracor Inc. | Passivated porous polymer supports and methods for the preparation and use of same |
| WO1994022918A1 (en) * | 1993-03-29 | 1994-10-13 | Minnesota Mining And Manufacturing Company | Method of coupling ligands within porous supports (p.e. azlactone) and uses thereof |
| SE9503925D0 (sv) * | 1995-11-07 | 1995-11-07 | Pharmacia Biotech Ab | Separationsmedium för IgG |
| SE9601368D0 (sv) * | 1996-04-11 | 1996-04-11 | Pharmacia Biotech Ab | Process for the production of a porous cross-linked polysaccharide gel |
| US6599620B2 (en) * | 1997-01-07 | 2003-07-29 | Kaneka Corporation | Cellulosic particles, spherical object comprising cross-linked polymer particles, and adsorbent for body fluid purification |
| SE9700383D0 (sv) * | 1997-02-04 | 1997-02-04 | Pharmacia Biotech Ab | An adsorption/separation method and a medium for adsorption/separation |
| SE0004929D0 (sv) * | 2000-12-29 | 2000-12-29 | Apbiotech Ab | A method for producing liquid chromatography matrices |
| SE0200943D0 (sv) * | 2002-03-25 | 2002-03-25 | Amersham Biosciences Ab | Mutant protein |
| SE0300482D0 (sv) * | 2003-02-21 | 2003-02-21 | Amersham Biosciences Ab | Inorganic beads with hierarchical pore structures |
| US7700743B2 (en) * | 2003-07-22 | 2010-04-20 | Millipore Corporation | Immobilised affinity medium and its use in separation |
| WO2006024497A1 (en) * | 2004-08-30 | 2006-03-09 | Lonza Biologics Plc. | Affinity- plus ion exchange- chromatography for purifying antibodies |
-
2005
- 2005-12-12 WO PCT/SE2005/001900 patent/WO2006065208A1/en not_active Ceased
- 2005-12-12 EP EP05815565A patent/EP1830947A4/en not_active Withdrawn
- 2005-12-12 CA CA2586803A patent/CA2586803C/en not_active Expired - Lifetime
- 2005-12-12 JP JP2007546603A patent/JP5787461B2/ja not_active Expired - Lifetime
- 2005-12-12 AU AU2005317279A patent/AU2005317279C1/en not_active Expired
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