JP2008523102A5 - - Google Patents
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- Publication number
- JP2008523102A5 JP2008523102A5 JP2007545718A JP2007545718A JP2008523102A5 JP 2008523102 A5 JP2008523102 A5 JP 2008523102A5 JP 2007545718 A JP2007545718 A JP 2007545718A JP 2007545718 A JP2007545718 A JP 2007545718A JP 2008523102 A5 JP2008523102 A5 JP 2008523102A5
- Authority
- JP
- Japan
- Prior art keywords
- carbon atoms
- pharmaceutical composition
- alkyl
- hydrogen atom
- pde4 modulator
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 0 CCN(C(*)*C)C(C)=O Chemical compound CCN(C(*)*C)C(C)=O 0.000 description 3
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63498204P | 2004-12-13 | 2004-12-13 | |
| PCT/US2005/045071 WO2006065814A1 (en) | 2004-12-13 | 2005-12-12 | Compositions comprising pde4 modulators and their use for the treatment or prevention of airway inflammation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008523102A JP2008523102A (ja) | 2008-07-03 |
| JP2008523102A5 true JP2008523102A5 (enExample) | 2009-02-12 |
Family
ID=36121316
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007545718A Abandoned JP2008523102A (ja) | 2004-12-13 | 2005-12-12 | Ｐｄｅ４モジュレーターを含有する組成物及び気道炎症の治療又は予防のためのそれらの使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20060148882A1 (enExample) |
| EP (1) | EP1838294A1 (enExample) |
| JP (1) | JP2008523102A (enExample) |
| KR (1) | KR20070092276A (enExample) |
| CN (1) | CN101111235A (enExample) |
| AR (1) | AR052047A1 (enExample) |
| AU (1) | AU2005316593A1 (enExample) |
| BR (1) | BRPI0519030A2 (enExample) |
| CA (1) | CA2590903A1 (enExample) |
| IL (1) | IL183858A0 (enExample) |
| MX (1) | MX2007006992A (enExample) |
| WO (1) | WO2006065814A1 (enExample) |
| ZA (1) | ZA200705540B (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050100529A1 (en) * | 2003-11-06 | 2005-05-12 | Zeldis Jerome B. | Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of asbestos-related diseases and disorders |
| CA2563377A1 (en) * | 2004-04-23 | 2005-11-03 | Celgene Corporation | Methods of using and compositions comprising pde4 modulators for the treatment and management of pulmonary hypertension |
| AU2006305620A1 (en) * | 2005-10-19 | 2007-04-26 | Ranbaxy Laboratories Limited | Compositions of phosphodiesterase type IV inhibitors |
| MY160002A (en) * | 2009-02-10 | 2017-02-15 | Celgene Corp | Methods of using and compositions comprising pde4 modulators for treatment, prevention and management of tuberculosis |
| KR101514866B1 (ko) | 2009-05-14 | 2015-04-24 | 티안진 헤메이 바이오-텍 컴퍼니 리미티드 | 티오펜 유도체 |
| WO2011127019A2 (en) * | 2010-04-07 | 2011-10-13 | Celgene Corporation | Methods for treating respiratory viral infection |
| MX354210B (es) | 2010-12-16 | 2018-02-16 | Celgene Corp | Formas farmaceuticas orales de liberacion controlada de farmacos escasamente solubles y los usos de estas. |
| ES2632979T3 (es) * | 2011-01-10 | 2017-09-18 | Celgene Corporation | Formas de dosificación oral de {2-[(1S)-1-(3-etoxi-4-metoxi-fenil)-2-metanosulfonil-etil]-3-oxo-2,3-dihidro-1H-isoindol-4-il}-amida de ácido ciclopropanocarboxílico |
| ES2673114T3 (es) * | 2011-01-10 | 2018-06-19 | Celgene Corporation | Derivados de fenetilsulfona isoindolina como inhibidores de PDE 4 y/o citoquinas |
| ES2711100T3 (es) * | 2011-03-07 | 2019-04-30 | Celgene Corp | Métodos para tratar enfermedades usando compuestos isoindolina |
| ES2661583T3 (es) | 2011-04-28 | 2018-04-02 | Celgene Corporation | Métodos y composiciones usando inhibidores de PDE4 para el tratamiento y gestión de enfermedades autoinmunes e inflamatorias |
| US9872854B2 (en) | 2013-03-14 | 2018-01-23 | Celgene Corporation | Methods for the treatment of psoriatic arthritis using apremilast |
| EP3096749B1 (en) * | 2014-01-24 | 2019-05-15 | Celgene Corporation | Methods for the treatment of obesity using apremilast |
| WO2016025686A1 (en) | 2014-08-15 | 2016-02-18 | Celgene Corporation | Dosage titration of apremilast for the treatment of diseases ameliorated by pde4 inhibition |
| US10011611B2 (en) | 2015-08-14 | 2018-07-03 | Reaction Biology Corp. | Histone deacetylase inhibitors and methods for use thereof |
| WO2018036469A1 (zh) * | 2016-08-22 | 2018-03-01 | 南京明德新药研发股份有限公司 | Pde4抑制剂 |
| US11337964B2 (en) * | 2017-02-28 | 2022-05-24 | Kangpu Biopharmaceuticals, Ltd. | Isoindoline derivative, pharmaceutical composition and use thereof |
| CN110573148A (zh) * | 2017-03-16 | 2019-12-13 | 武田有限公司 | 特发性肺纤维化的治疗 |
| GB202306663D0 (en) | 2023-05-05 | 2023-06-21 | Union Therapeutics As | Combination therapy |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6020358A (en) * | 1998-10-30 | 2000-02-01 | Celgene Corporation | Substituted phenethylsulfones and method of reducing TNFα levels |
| US6667316B1 (en) * | 1999-11-12 | 2003-12-23 | Celgene Corporation | Pharmaceutically active isoindoline derivatives |
| US6699899B1 (en) * | 1999-12-21 | 2004-03-02 | Celgene Corporation | Substituted acylhydroxamic acids and method of reducing TNFα levels |
| US7276529B2 (en) * | 2002-03-20 | 2007-10-02 | Celgene Corporation | Methods of the treatment or prevention of exercise-induced asthma using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione |
| US6962940B2 (en) * | 2002-03-20 | 2005-11-08 | Celgene Corporation | (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof |
| WO2004043378A2 (en) * | 2002-11-06 | 2004-05-27 | Celgene Corporation | Methods and compositions using selective cytokine inhibitory drugs for treatment and management of cancers and other diseases |
| KR20050075435A (ko) * | 2002-11-18 | 2005-07-20 | 셀진 코포레이션 | (＋)-３-(３,４-디메톡시-페닐)-３-(１-옥소-１,３-디히드로-이소인돌-２-일)-프로피온아미드의 사용 방법 및 그를포함하는 조성물 |
| KR20050090435A (ko) * | 2002-12-30 | 2005-09-13 | 셀진 코포레이션 | 플루오로알콕시-치환된 1,3-디히드로-이소인돌릴 화합물 및그의 제약학적 용도 |
| CA2563377A1 (en) * | 2004-04-23 | 2005-11-03 | Celgene Corporation | Methods of using and compositions comprising pde4 modulators for the treatment and management of pulmonary hypertension |
| CN1984651A (zh) * | 2004-05-05 | 2007-06-20 | 细胞基因公司 | 使用选择性细胞因子抑制药治疗和控制癌症和其它疾病的方法和组合物 |
| US7244759B2 (en) * | 2004-07-28 | 2007-07-17 | Celgene Corporation | Isoindoline compounds and methods of making and using the same |
-
2005
- 2005-12-12 MX MX2007006992A patent/MX2007006992A/es unknown
- 2005-12-12 WO PCT/US2005/045071 patent/WO2006065814A1/en not_active Ceased
- 2005-12-12 EP EP05853888A patent/EP1838294A1/en not_active Withdrawn
- 2005-12-12 CN CNA2005800476591A patent/CN101111235A/zh active Pending
- 2005-12-12 CA CA002590903A patent/CA2590903A1/en not_active Abandoned
- 2005-12-12 ZA ZA200705540A patent/ZA200705540B/xx unknown
- 2005-12-12 JP JP2007545718A patent/JP2008523102A/ja not_active Abandoned
- 2005-12-12 AU AU2005316593A patent/AU2005316593A1/en not_active Abandoned
- 2005-12-12 BR BRPI0519030-4A patent/BRPI0519030A2/pt not_active IP Right Cessation
- 2005-12-12 KR KR1020077015958A patent/KR20070092276A/ko not_active Withdrawn
- 2005-12-13 AR ARP050105222A patent/AR052047A1/es not_active Application Discontinuation
- 2005-12-13 US US11/299,702 patent/US20060148882A1/en not_active Abandoned
-
2007
- 2007-06-12 IL IL183858A patent/IL183858A0/en unknown
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