JP2025512474A5 - - Google Patents
Info
- Publication number
- JP2025512474A5 JP2025512474A5 JP2024560695A JP2024560695A JP2025512474A5 JP 2025512474 A5 JP2025512474 A5 JP 2025512474A5 JP 2024560695 A JP2024560695 A JP 2024560695A JP 2024560695 A JP2024560695 A JP 2024560695A JP 2025512474 A5 JP2025512474 A5 JP 2025512474A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- pharmaceutically acceptable
- acceptable salt
- jak
- heteroarylene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263331463P | 2022-04-15 | 2022-04-15 | |
| US63/331,463 | 2022-04-15 | ||
| PCT/US2023/018658 WO2023201044A2 (en) | 2022-04-15 | 2023-04-14 | Jak inhibitor analogs, formulations, and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025512474A JP2025512474A (ja) | 2025-04-17 |
| JP2025512474A5 true JP2025512474A5 (enExample) | 2026-04-21 |
Family
ID=88330277
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024560695A Pending JP2025512474A (ja) | 2022-04-15 | 2023-04-14 | Ｊａｋ阻害アナログ、製剤、及びそれらの使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20250257069A1 (enExample) |
| EP (1) | EP4507691A4 (enExample) |
| JP (1) | JP2025512474A (enExample) |
| KR (1) | KR20250003838A (enExample) |
| CN (1) | CN119923257A (enExample) |
| WO (1) | WO2023201044A2 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20260019479A (ko) | 2023-05-04 | 2026-02-10 | 레볼루션 메디슨즈, 인크. | Ras 관련 질환 또는 장애를 위한 병용 요법 |
| CN121889155A (zh) | 2023-08-07 | 2026-04-17 | 锐新医药公司 | 用于治疗ras蛋白相关疾病或病症的rmc-6291 |
| AU2024360465A1 (en) | 2023-10-12 | 2026-04-09 | Revolution Medicines, Inc. | Macrocyclic ras inhibitors |
| WO2025171296A1 (en) | 2024-02-09 | 2025-08-14 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2025240847A1 (en) | 2024-05-17 | 2025-11-20 | Revolution Medicines, Inc. | Ras inhibitors |
| US20250375445A1 (en) | 2024-06-07 | 2025-12-11 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
| WO2025265060A1 (en) | 2024-06-21 | 2025-12-26 | Revolution Medicines, Inc. | Therapeutic compositions and methods for managing treatment-related effects |
| WO2026006747A1 (en) | 2024-06-28 | 2026-01-02 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026015790A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015801A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015825A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Use of ras inhibitor for treating pancreatic cancer |
| WO2026015796A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026050446A1 (en) | 2024-08-29 | 2026-03-05 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026072904A2 (en) | 2024-09-26 | 2026-04-02 | Revolution Medicines, Inc. | Compositions and methods for treating lung cancer |
| WO2026090116A2 (en) | 2024-10-21 | 2026-04-30 | Revolution Medicines, Inc. | Ras inhibitors |
| US20260108528A1 (en) | 2024-10-22 | 2026-04-23 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
| WO2026090245A1 (en) | 2024-10-22 | 2026-04-30 | Revolution Medicines, Inc. | Use of ras inhibitors for treating cancer |
| WO2026106912A1 (en) | 2024-11-12 | 2026-05-21 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026112260A1 (en) | 2024-11-21 | 2026-05-28 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026122764A2 (en) | 2024-12-06 | 2026-06-11 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026128688A2 (en) | 2024-12-13 | 2026-06-18 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026161839A1 (en) | 2025-01-27 | 2026-07-30 | Revolution Medicines, Inc. | Ras inhibitors |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008009458A1 (en) * | 2006-07-21 | 2008-01-24 | Novartis Ag | 2, 4 -di (arylaminio) -pyrimidine-5-carboxamide compounds as jak kinases inhibitors |
| EP3609903A1 (en) * | 2017-05-23 | 2020-02-19 | Theravance Biopharma R&D IP, LLC | Thiocarbamate prodrugs of tofacitinib |
| BR112019024509A2 (pt) * | 2017-05-23 | 2020-06-23 | Theravance Biopharma R&D Ip, Llc | Glicuronídeo de pró-fármacos dos inibidores da janus quinase |
| AU2020228662A1 (en) * | 2019-02-28 | 2021-09-09 | Monash University | Lipid prodrugs of JAK inhibitors and uses thereof |
| WO2022068933A1 (en) * | 2020-09-30 | 2022-04-07 | Cullgen (Shanghai) , Inc. | Compounds and methods of treating diseases |
| CN114262321B (zh) * | 2021-12-07 | 2024-08-09 | 中国药科大学 | 一种双稳态光调控小分子蛋白降解剂、制备方法及应用 |
-
2023
- 2023-04-14 CN CN202380040536.3A patent/CN119923257A/zh active Pending
- 2023-04-14 US US18/856,839 patent/US20250257069A1/en active Pending
- 2023-04-14 KR KR1020247037966A patent/KR20250003838A/ko active Pending
- 2023-04-14 EP EP23789005.8A patent/EP4507691A4/en active Pending
- 2023-04-14 JP JP2024560695A patent/JP2025512474A/ja active Pending
- 2023-04-14 WO PCT/US2023/018658 patent/WO2023201044A2/en not_active Ceased
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