JP2025512474A5 - - Google Patents

Info

Publication number
JP2025512474A5
JP2025512474A5 JP2024560695A JP2024560695A JP2025512474A5 JP 2025512474 A5 JP2025512474 A5 JP 2025512474A5 JP 2024560695 A JP2024560695 A JP 2024560695A JP 2024560695 A JP2024560695 A JP 2024560695A JP 2025512474 A5 JP2025512474 A5 JP 2025512474A5
Authority
JP
Japan
Prior art keywords
alkyl
pharmaceutically acceptable
acceptable salt
jak
heteroarylene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024560695A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025512474A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/018658 external-priority patent/WO2023201044A2/en
Publication of JP2025512474A publication Critical patent/JP2025512474A/ja
Publication of JP2025512474A5 publication Critical patent/JP2025512474A5/ja
Pending legal-status Critical Current

Links

JP2024560695A 2022-04-15 2023-04-14 Jak阻害アナログ、製剤、及びそれらの使用 Pending JP2025512474A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263331463P 2022-04-15 2022-04-15
US63/331,463 2022-04-15
PCT/US2023/018658 WO2023201044A2 (en) 2022-04-15 2023-04-14 Jak inhibitor analogs, formulations, and uses thereof

Publications (2)

Publication Number Publication Date
JP2025512474A JP2025512474A (ja) 2025-04-17
JP2025512474A5 true JP2025512474A5 (enExample) 2026-04-21

Family

ID=88330277

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024560695A Pending JP2025512474A (ja) 2022-04-15 2023-04-14 Jak阻害アナログ、製剤、及びそれらの使用

Country Status (6)

Country Link
US (1) US20250257069A1 (enExample)
EP (1) EP4507691A2 (enExample)
JP (1) JP2025512474A (enExample)
KR (1) KR20250003838A (enExample)
CN (1) CN119923257A (enExample)
WO (1) WO2023201044A2 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202508595A (zh) 2023-05-04 2025-03-01 美商銳新醫藥公司 用於ras相關疾病或病症之組合療法
US20250049810A1 (en) 2023-08-07 2025-02-13 Revolution Medicines, Inc. Methods of treating a ras protein-related disease or disorder
AU2024360465A1 (en) 2023-10-12 2026-04-09 Revolution Medicines, Inc. Macrocyclic ras inhibitors
WO2025171296A1 (en) 2024-02-09 2025-08-14 Revolution Medicines, Inc. Ras inhibitors
TW202547461A (zh) 2024-05-17 2025-12-16 美商銳新醫藥公司 Ras抑制劑
WO2025255438A1 (en) 2024-06-07 2025-12-11 Revolution Medicines, Inc. Methods of treating a ras protein-related disease or disorder
WO2025265060A1 (en) 2024-06-21 2025-12-26 Revolution Medicines, Inc. Therapeutic compositions and methods for managing treatment-related effects
WO2026006747A1 (en) 2024-06-28 2026-01-02 Revolution Medicines, Inc. Ras inhibitors
WO2026015801A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015790A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015796A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015825A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Use of ras inhibitor for treating pancreatic cancer
WO2026050446A1 (en) 2024-08-29 2026-03-05 Revolution Medicines, Inc. Ras inhibitors
WO2026072904A2 (en) 2024-09-26 2026-04-02 Revolution Medicines, Inc. Compositions and methods for treating lung cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH12019502605A1 (en) * 2017-05-23 2020-10-26 Theravance Biopharma R&D Ip Llc Glucuronide prodrugs of janus kinase inhibitors
EP3609903A1 (en) * 2017-05-23 2020-02-19 Theravance Biopharma R&D IP, LLC Thiocarbamate prodrugs of tofacitinib
CA3130349A1 (en) * 2019-02-28 2020-09-03 Puretech Lyt, Inc. Lipid prodrugs of jak inhibitors and uses thereof

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