JP2008521189A - 質量分析計 - Google Patents
質量分析計 Download PDFInfo
- Publication number
- JP2008521189A JP2008521189A JP2007542101A JP2007542101A JP2008521189A JP 2008521189 A JP2008521189 A JP 2008521189A JP 2007542101 A JP2007542101 A JP 2007542101A JP 2007542101 A JP2007542101 A JP 2007542101A JP 2008521189 A JP2008521189 A JP 2008521189A
- Authority
- JP
- Japan
- Prior art keywords
- mass
- ion
- ion guide
- filter device
- ions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
- H01J49/34—Dynamic spectrometers
- H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
- H01J49/4205—Device types
- H01J49/421—Mass filters, i.e. deviating unwanted ions without trapping
- H01J49/4215—Quadrupole mass filters
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
- H01J49/34—Dynamic spectrometers
- H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
- H01J49/426—Methods for controlling ions
- H01J49/427—Ejection and selection methods
- H01J49/428—Applying a notched broadband signal
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Electron Tubes For Measurement (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0425426.4A GB0425426D0 (en) | 2004-11-18 | 2004-11-18 | Mass spectrometer |
| US63195604P | 2004-11-30 | 2004-11-30 | |
| PCT/GB2005/004457 WO2006054101A2 (en) | 2004-11-18 | 2005-11-18 | Mass spectrometer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008521189A true JP2008521189A (ja) | 2008-06-19 |
| JP2008521189A5 JP2008521189A5 (enExample) | 2008-12-11 |
Family
ID=33548493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007542101A Pending JP2008521189A (ja) | 2004-11-18 | 2005-11-18 | 質量分析計 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8952320B2 (enExample) |
| EP (1) | EP1812950A2 (enExample) |
| JP (1) | JP2008521189A (enExample) |
| CA (1) | CA2586519A1 (enExample) |
| GB (2) | GB0425426D0 (enExample) |
| WO (1) | WO2006054101A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4756096B2 (ja) * | 2007-01-25 | 2011-08-24 | マイクロマス ユーケー リミテッド | 質量分析計 |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020115056A1 (en) * | 2000-12-26 | 2002-08-22 | Goodlett David R. | Rapid and quantitative proteome analysis and related methods |
| GB0305796D0 (en) | 2002-07-24 | 2003-04-16 | Micromass Ltd | Method of mass spectrometry and a mass spectrometer |
| GB0514964D0 (en) * | 2005-07-21 | 2005-08-24 | Ms Horizons Ltd | Mass spectrometer devices & methods of performing mass spectrometry |
| JP4911781B2 (ja) * | 2004-12-07 | 2012-04-04 | マイクロマス ユーケー リミテッド | 質量分析計 |
| GB2432712B (en) * | 2005-11-23 | 2007-12-27 | Micromass Ltd | Mass spectrometer |
| CA2656197C (en) * | 2006-07-10 | 2015-06-16 | John Brian Hoyes | Mass spectrometer |
| GB0622780D0 (en) * | 2006-11-15 | 2006-12-27 | Micromass Ltd | Mass spectrometer |
| EP2126961B1 (en) * | 2007-02-24 | 2014-06-18 | Sociedad Europea De Analisis Diferencial De Movilidad S.L. | Method to accurately discriminate gas phase ions with several filtering devices in tandem |
| DE102007009272B3 (de) * | 2007-02-26 | 2008-05-15 | Bruker Daltonik Gmbh | Auswertung von Spektren in Schwingungs-Massenspektrometern |
| DE102007017055B4 (de) * | 2007-04-11 | 2011-06-22 | Bruker Daltonik GmbH, 28359 | Messung der Mobilität massenselektierter Ionen |
| US8901487B2 (en) | 2007-07-20 | 2014-12-02 | George Washington University | Subcellular analysis by laser ablation electrospray ionization mass spectrometry |
| US7964843B2 (en) | 2008-07-18 | 2011-06-21 | The George Washington University | Three-dimensional molecular imaging by infrared laser ablation electrospray ionization mass spectrometry |
| US8067730B2 (en) | 2007-07-20 | 2011-11-29 | The George Washington University | Laser ablation electrospray ionization (LAESI) for atmospheric pressure, In vivo, and imaging mass spectrometry |
| US7718957B2 (en) * | 2008-06-03 | 2010-05-18 | Battelle Memorial Institute | Dynamic multiplexed analysis method using ion mobility spectrometer |
| US20100237236A1 (en) * | 2009-03-20 | 2010-09-23 | Applera Corporation | Method Of Processing Multiple Precursor Ions In A Tandem Mass Spectrometer |
| US8829426B2 (en) | 2011-07-14 | 2014-09-09 | The George Washington University | Plume collimation for laser ablation electrospray ionization mass spectrometry |
| GB201118579D0 (en) * | 2011-10-27 | 2011-12-07 | Micromass Ltd | Control of ion populations |
| EP2807669A2 (en) | 2012-01-24 | 2014-12-03 | Thermo Finnigan LLC | Multinotch isolation for ms3 mass analysis |
| GB201205009D0 (en) * | 2012-03-22 | 2012-05-09 | Micromass Ltd | Multi-dimensional survey scans for improved data dependent acquisitions (DDA) |
| WO2013176901A1 (en) | 2012-05-23 | 2013-11-28 | President And Fellows Of Harvard College | Mass spectrometry for multiplexed quantitation using multiple frequency notches |
| CN103515183B (zh) * | 2012-06-20 | 2017-06-23 | 株式会社岛津制作所 | 离子导引装置和离子导引方法 |
| JP6491097B2 (ja) | 2012-10-22 | 2019-03-27 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 質量分析法を使用する正確で干渉のない多重定量プロテオミクス |
| EP2956957B1 (en) * | 2013-02-18 | 2020-01-22 | Micromass UK Limited | Device allowing improved reaction monitoring of gas phase reactions in mass spectrometers using an auto ejection ion trap |
| US20150380231A1 (en) * | 2013-02-18 | 2015-12-31 | Micromass Uk Limited | Improved Efficiency and Precise Control of Gas Phase Reactions in Mass Spectrometers Using an Auto Ejection Ion Trap |
| WO2014159478A1 (en) * | 2013-03-14 | 2014-10-02 | President And Fellows Of Harvard College | Adjusting precursor ion populations in mass spectrometry using dynamic isolation waveforms |
| GB201315145D0 (en) | 2013-08-23 | 2013-10-09 | Smiths Detection Watford Ltd | Ion Modification |
| US9997340B2 (en) * | 2013-09-13 | 2018-06-12 | Dh Technologies Development Pte. Ltd. | RF-only detection scheme and simultaneous detection of multiple ions |
| WO2015056066A1 (en) * | 2013-10-16 | 2015-04-23 | Dh Technologies Development Pte. Ltd. | Systems and methods for identifying precursor ions from product ions using arbitrary transmission windowing |
| WO2015068001A1 (en) | 2013-11-07 | 2015-05-14 | Dh Technologies Development Pte. Ltd. | Multiplexing of ions for improved sensitivity |
| WO2015071648A2 (en) | 2013-11-12 | 2015-05-21 | Micromass Uk Limited | Ion trap mass spectrometers |
| GB201319942D0 (en) * | 2013-11-12 | 2013-12-25 | Micromass Ltd | Ion Trap Mass Spectrometers |
| WO2015118321A1 (en) | 2014-02-04 | 2015-08-13 | Micromass Uk Limited | Optimized multiple reaction monitoring or single ion recording method |
| WO2015162415A1 (en) * | 2014-04-23 | 2015-10-29 | Micromass Uk Limited | Identification and removal of chemical noise for improved ms and ms/ms analysis |
| CN106663590B (zh) * | 2014-06-10 | 2019-03-26 | 英国质谱公司 | 离子引导器 |
| US9875885B2 (en) * | 2015-05-11 | 2018-01-23 | Thermo Finnigan Llc | Systems and methods for ion isolation |
| EP3357080B1 (en) | 2015-10-01 | 2024-05-01 | DH Technologies Development PTE. Ltd. | Mass-selective axial ejection linear ion trap |
| US9741552B2 (en) * | 2015-12-22 | 2017-08-22 | Bruker Daltonics, Inc. | Triple quadrupole mass spectrometry coupled to trapped ion mobility separation |
| US11085927B2 (en) | 2016-06-03 | 2021-08-10 | President And Fellows Of Harvard College | Techniques for high throughput targeted proteomic analysis and related systems and methods |
| CN109643635B (zh) * | 2016-07-25 | 2021-08-17 | Dh科技发展私人贸易有限公司 | 用于在扫描swath数据中识别前体及产物离子对的系统及方法 |
| EP3577677B1 (en) | 2017-02-01 | 2024-09-04 | DH Technologies Development PTE. Ltd. | Fourier transform mass spectrometer |
| GB2563565B (en) * | 2017-04-13 | 2022-05-11 | Micromass Ltd | Mass spectrometry with increased duty cycle |
| GB2572846B (en) | 2018-02-16 | 2020-09-16 | Micromass Ltd | Quadrupole devices |
| WO2020183160A1 (en) | 2019-03-11 | 2020-09-17 | Micromass Uk Limited | Quadrupole devices |
| JP2022534468A (ja) | 2019-05-31 | 2022-08-01 | ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド | 走査型swathデータのリアルタイムエンコーディングおよび前駆体推測のための確率的フレームワークのための方法 |
| CN111309060A (zh) * | 2020-03-27 | 2020-06-19 | 北京环拓科技有限公司 | 一种大气负氧离子观测仪的控制方法 |
| EP3916755A1 (en) * | 2020-05-26 | 2021-12-01 | Thermo Finnigan LLC | Methods and apparatus for high speed mass spectrometry |
| GB202011470D0 (en) | 2020-07-24 | 2020-09-09 | Micromass Ltd | ION mobility separation |
| GB202306186D0 (en) * | 2023-04-27 | 2023-06-14 | Micromass Ltd | Mass spectrometer having parallel precursor ion isolation |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5187365A (en) * | 1991-02-28 | 1993-02-16 | Teledyne Mec | Mass spectrometry method using time-varying filtered noise |
| JPH09180672A (ja) * | 1995-12-18 | 1997-07-11 | Hewlett Packard Co <Hp> | ノッチ・フィルタ及び目標イオンの除去方法 |
| JPH11154486A (ja) * | 1997-08-22 | 1999-06-08 | Micromass Ltd | タンデム式質量分光分析の方法とタンデム式質量分光分析計 |
| US6093929A (en) * | 1997-05-16 | 2000-07-25 | Mds Inc. | High pressure MS/MS system |
| JP2001526448A (ja) * | 1997-12-04 | 2001-12-18 | ユニヴァーシティー オブ マニトバ | 四重極イオンガイド中でイオンを選択的に衝突誘発解離する方法および装置 |
| WO2003091721A1 (en) * | 2002-04-24 | 2003-11-06 | Mds Inc. , Doing Business As Mds Sciex | Apparatus and method for mobility separation of ions utilizing an ion guide with an axial field and counterflow of gas |
| JP2003338261A (ja) * | 2002-05-20 | 2003-11-28 | Shimadzu Corp | イオントラップ型質量分析装置 |
| JP2005524211A (ja) * | 2002-04-29 | 2005-08-11 | エムディーエス インコーポレイテッド ドゥーイング ビジネス アズ エムディーエス サイエックス | 衝突エネルギーを変化させることによる質量分析における広いイオンフラグメント化範囲を得る方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3334225A (en) | 1964-04-24 | 1967-08-01 | California Inst Res Found | Quadrupole mass filter with means to generate a noise spectrum exclusive of the resonant frequency of the desired ions to deflect stable ions |
| US5134286A (en) * | 1991-02-28 | 1992-07-28 | Teledyne Cme | Mass spectrometry method using notch filter |
| US5449905A (en) * | 1992-05-14 | 1995-09-12 | Teledyne Et | Method for generating filtered noise signal and broadband signal having reduced dynamic range for use in mass spectrometry |
| US5598001A (en) * | 1996-01-30 | 1997-01-28 | Hewlett-Packard Company | Mass selective multinotch filter with orthogonal excision fields |
| US6177668B1 (en) | 1996-06-06 | 2001-01-23 | Mds Inc. | Axial ejection in a multipole mass spectrometer |
| US5793038A (en) * | 1996-12-10 | 1998-08-11 | Varian Associates, Inc. | Method of operating an ion trap mass spectrometer |
| WO1998052209A1 (en) * | 1997-05-12 | 1998-11-19 | Mds Inc. | Rf-only mass spectrometer with auxiliary excitation |
| GB2381653A (en) * | 2001-11-05 | 2003-05-07 | Shimadzu Res Lab Europe Ltd | A quadrupole ion trap device and methods of operating a quadrupole ion trap device |
| WO2003056604A1 (en) * | 2001-12-21 | 2003-07-10 | Mds Inc., Doing Business As Mds Sciex | Use of notched broadband waveforms in a linear ion trap |
| US6900431B2 (en) * | 2003-03-21 | 2005-05-31 | Predicant Biosciences, Inc. | Multiplexed orthogonal time-of-flight mass spectrometer |
| CA2574965A1 (en) * | 2004-07-27 | 2006-02-09 | John A. Mclean | Multiplex data acquisition modes for ion mobility-mass spectrometry |
| US7456396B2 (en) * | 2004-08-19 | 2008-11-25 | Thermo Finnigan Llc | Isolating ions in quadrupole ion traps for mass spectrometry |
-
2004
- 2004-11-18 GB GBGB0425426.4A patent/GB0425426D0/en not_active Ceased
-
2005
- 2005-11-18 GB GB0523569A patent/GB2421842B/en not_active Expired - Fee Related
- 2005-11-18 WO PCT/GB2005/004457 patent/WO2006054101A2/en not_active Ceased
- 2005-11-18 US US11/719,665 patent/US8952320B2/en active Active
- 2005-11-18 CA CA002586519A patent/CA2586519A1/en not_active Abandoned
- 2005-11-18 JP JP2007542101A patent/JP2008521189A/ja active Pending
- 2005-11-18 EP EP05804395A patent/EP1812950A2/en not_active Withdrawn
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5187365A (en) * | 1991-02-28 | 1993-02-16 | Teledyne Mec | Mass spectrometry method using time-varying filtered noise |
| JPH09180672A (ja) * | 1995-12-18 | 1997-07-11 | Hewlett Packard Co <Hp> | ノッチ・フィルタ及び目標イオンの除去方法 |
| US6093929A (en) * | 1997-05-16 | 2000-07-25 | Mds Inc. | High pressure MS/MS system |
| JPH11154486A (ja) * | 1997-08-22 | 1999-06-08 | Micromass Ltd | タンデム式質量分光分析の方法とタンデム式質量分光分析計 |
| JP2001526448A (ja) * | 1997-12-04 | 2001-12-18 | ユニヴァーシティー オブ マニトバ | 四重極イオンガイド中でイオンを選択的に衝突誘発解離する方法および装置 |
| WO2003091721A1 (en) * | 2002-04-24 | 2003-11-06 | Mds Inc. , Doing Business As Mds Sciex | Apparatus and method for mobility separation of ions utilizing an ion guide with an axial field and counterflow of gas |
| JP2005524211A (ja) * | 2002-04-29 | 2005-08-11 | エムディーエス インコーポレイテッド ドゥーイング ビジネス アズ エムディーエス サイエックス | 衝突エネルギーを変化させることによる質量分析における広いイオンフラグメント化範囲を得る方法 |
| JP2003338261A (ja) * | 2002-05-20 | 2003-11-28 | Shimadzu Corp | イオントラップ型質量分析装置 |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4756096B2 (ja) * | 2007-01-25 | 2011-08-24 | マイクロマス ユーケー リミテッド | 質量分析計 |
| US8076637B2 (en) | 2007-01-25 | 2011-12-13 | Micromass Uk Limited | Mass spectrometer |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2421842B (en) | 2007-08-01 |
| GB0523569D0 (en) | 2005-12-28 |
| WO2006054101A2 (en) | 2006-05-26 |
| US20090194688A1 (en) | 2009-08-06 |
| US8952320B2 (en) | 2015-02-10 |
| GB2421842A (en) | 2006-07-05 |
| GB0425426D0 (en) | 2004-12-22 |
| WO2006054101A3 (en) | 2007-01-18 |
| EP1812950A2 (en) | 2007-08-01 |
| CA2586519A1 (en) | 2006-05-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20081023 |
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| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20081023 |
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| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20110721 |
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| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20110726 |
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| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20111220 |