JP2008518999A5 - - Google Patents

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Publication number
JP2008518999A5
JP2008518999A5 JP2007539549A JP2007539549A JP2008518999A5 JP 2008518999 A5 JP2008518999 A5 JP 2008518999A5 JP 2007539549 A JP2007539549 A JP 2007539549A JP 2007539549 A JP2007539549 A JP 2007539549A JP 2008518999 A5 JP2008518999 A5 JP 2008518999A5
Authority
JP
Japan
Prior art keywords
alkyl
cycloalkyl
phenyl
optionally substituted
heterocyclyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
JP2007539549A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008518999A (ja
Filing date
Publication date
Priority claimed from EP04026441A external-priority patent/EP1655283A1/en
Application filed filed Critical
Publication of JP2008518999A publication Critical patent/JP2008518999A/ja
Publication of JP2008518999A5 publication Critical patent/JP2008518999A5/ja
Abandoned legal-status Critical Current

Links

JP2007539549A 2004-11-08 2005-11-08 11β−HSD1阻害剤 Abandoned JP2008518999A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04026441A EP1655283A1 (en) 2004-11-08 2004-11-08 11beta-HSD1 Inhibitors
PCT/EP2005/011933 WO2006048330A1 (en) 2004-11-08 2005-11-08 11βετα-hsd1 inhibitors

Publications (2)

Publication Number Publication Date
JP2008518999A JP2008518999A (ja) 2008-06-05
JP2008518999A5 true JP2008518999A5 (US07928230-20110419-C00074.png) 2008-12-25

Family

ID=34927280

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007539549A Abandoned JP2008518999A (ja) 2004-11-08 2005-11-08 11β−HSD1阻害剤

Country Status (7)

Country Link
US (1) US20090069323A1 (US07928230-20110419-C00074.png)
EP (2) EP1655283A1 (US07928230-20110419-C00074.png)
JP (1) JP2008518999A (US07928230-20110419-C00074.png)
AT (1) ATE427932T1 (US07928230-20110419-C00074.png)
DE (1) DE602005013812D1 (US07928230-20110419-C00074.png)
DK (1) DK1814846T3 (US07928230-20110419-C00074.png)
WO (1) WO2006048330A1 (US07928230-20110419-C00074.png)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100222316A1 (en) 2004-04-29 2010-09-02 Abbott Laboratories Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
US7880001B2 (en) 2004-04-29 2011-02-01 Abbott Laboratories Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme
US8415354B2 (en) 2004-04-29 2013-04-09 Abbott Laboratories Methods of use of inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
CA2594098C (en) 2005-01-05 2014-04-01 Abbott Laboratories Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
US8198331B2 (en) 2005-01-05 2012-06-12 Abbott Laboratories Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
CN101142172A (zh) 2005-01-05 2008-03-12 艾博特公司 11-β-羟甾类脱氢酶1型酶的抑制剂
US20090192198A1 (en) 2005-01-05 2009-07-30 Abbott Laboratories Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
US7572807B2 (en) 2005-06-09 2009-08-11 Bristol-Myers Squibb Company Heteroaryl 11-beta-hydroxysteroid dehydrogenase type I inhibitors
US7579360B2 (en) 2005-06-09 2009-08-25 Bristol-Myers Squibb Company Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
WO2007067817A1 (en) * 2005-12-07 2007-06-14 Cv Therapeutics, Inc. Abca1 elevating compounds
PE20110235A1 (es) 2006-05-04 2011-04-14 Boehringer Ingelheim Int Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
WO2007138112A2 (en) * 2006-06-01 2007-12-06 Devgen N.V. Compounds that interact with ion channels, in particular with ion channels from the kv family
CA2695613A1 (en) 2006-12-19 2008-06-26 Pharmos Corporation Sulfonamide derivatives with therapeutic indications
TW200845991A (en) 2007-01-12 2008-12-01 Smithkline Beecham Corp N-substituted glycine derivatives: hydroxylase inhibitors
JP5736098B2 (ja) 2007-08-21 2015-06-17 アッヴィ・インコーポレイテッド 中枢神経系障害を治療するための医薬組成物
US8119658B2 (en) 2007-10-01 2012-02-21 Bristol-Myers Squibb Company Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
US8927549B2 (en) 2008-11-21 2015-01-06 High Point Pharmaceuticals, Llc Adamantyl benzamide derivatives
ES2350077B1 (es) 2009-06-04 2011-11-04 Laboratorios Salvat, S.A. Compuestos inhibidores de 11beta-hidroxiesteroide deshidrogenasa de tipo 1.
US8394858B2 (en) 2009-12-03 2013-03-12 Novartis Ag Cyclohexane derivatives and uses thereof
CN101838227A (zh) * 2010-04-30 2010-09-22 孙德群 一种苯甲酰胺类除草剂的安全剂
WO2012015715A1 (en) 2010-07-27 2012-02-02 High Point Pharmaceuticals, Llc Substituted thiazol-2-ylamine derivatives, pharmaceutical compositions, and methods of use as 11-beta hsd1 modulators
JP2013539786A (ja) * 2010-10-11 2013-10-28 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 置換ベンズアミドおよびその使用法
BR112013020874A2 (pt) 2011-02-18 2019-05-21 Endo Pharmaceuticals Inc. composto, regime, método para a preparação do referido composto, e, uso de um composto
US9346795B2 (en) 2011-05-25 2016-05-24 Bristol-Myers Squibb Company Substituted sulfonamides useful as antiapoptotic Bcl inhibitors
WO2013112323A1 (en) 2012-01-23 2013-08-01 Eli Lilly And Company Phenyl methanesulfonamide derivatives useful as mgat - 2 inhibitors
AR089771A1 (es) * 2012-01-31 2014-09-17 Lilly Co Eli Derivados de bencil sulfonamida utiles como inhibidores de mogat-2
US8993568B2 (en) 2012-01-31 2015-03-31 Eli Lilly And Company Morpholinyl derivatives useful as MOGAT-2 inhibitors
TWI603957B (zh) 2012-08-15 2017-11-01 阿沙納生物科學有限責任公司 胺基氫茚化合物用於治療膀胱過動症及間質性膀胱炎之用途
EA201590696A1 (ru) * 2012-11-06 2015-08-31 Эли Лилли Энд Компани Новые бензилсульфонамидные соединения, подходящие в качестве ингибиторов mogat-2
CA2988147C (en) 2015-06-03 2023-06-13 Bristol-Myers Squibb Company 4-hydroxy-3-(heteroaryl)pyridine-2-one apj agonists for use in the treatment of cardiovascular disorders
AU2017275657B2 (en) 2016-06-02 2021-08-19 Novartis Ag Potassium channel modulators
CN110198935B (zh) 2017-01-23 2022-05-31 卡登特治疗公司 钾通道调节剂
CN111108105B (zh) 2017-09-22 2023-03-31 朱比兰特埃皮帕德有限公司 作为pad抑制剂的杂环化合物
SG11202003463XA (en) 2017-10-18 2020-05-28 Jubilant Epipad LLC Imidazo-pyridine compounds as pad inhibitors
CA3080677A1 (en) 2017-11-06 2019-05-09 Jubilant Prodel LLC Pyrimidine derivatives as inhibitors of pd1/pd-l1 activation
IL274762B2 (en) 2017-11-24 2023-10-01 Jubilant Episcribe Llc Novel heterocyclic compounds as PRMT5 inhibitors
SG11202008950PA (en) 2018-03-13 2020-10-29 Jubilant Prodel LLC Bicyclic compounds as inhibitors of pd1/pd-l1 interaction/activation
MA53978A (fr) 2018-10-22 2021-09-01 Cadent Therapeutics Inc Formes cristallines de modulateurs des canaux potassiques

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0206219D0 (en) * 2002-03-15 2002-05-01 Ferring Bv Non-Peptide GnRH antagonists
US20060058315A1 (en) * 2002-11-07 2006-03-16 Astrazeneca Ab 2-Oxo-ethanesulfonamide derivates

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