JP2008517884A5 - - Google Patents
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- Publication number
- JP2008517884A5 JP2008517884A5 JP2007537190A JP2007537190A JP2008517884A5 JP 2008517884 A5 JP2008517884 A5 JP 2008517884A5 JP 2007537190 A JP2007537190 A JP 2007537190A JP 2007537190 A JP2007537190 A JP 2007537190A JP 2008517884 A5 JP2008517884 A5 JP 2008517884A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- hydrogen
- group
- compound according
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 9
- 229910052739 hydrogen Inorganic materials 0.000 claims 5
- 239000001257 hydrogen Substances 0.000 claims 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 3
- 229910052736 halogen Inorganic materials 0.000 claims 3
- 150000002367 halogens Chemical class 0.000 claims 3
- 125000000094 2-phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 claims 2
- 125000003118 aryl group Chemical group 0.000 claims 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 2
- 150000002431 hydrogen Chemical class 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 230000004968 inflammatory condition Effects 0.000 claims 2
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- -1 2- iodo-4-hydroxy-5-methoxy-benzyl Chemical group 0.000 claims 1
- 208000000094 Chronic Pain Diseases 0.000 claims 1
- 208000004454 Hyperalgesia Diseases 0.000 claims 1
- 208000035154 Hyperesthesia Diseases 0.000 claims 1
- 208000002193 Pain Diseases 0.000 claims 1
- 125000003545 alkoxy group Chemical group 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000002757 inflammatory effect Effects 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 claims 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT002042A ITMI20042042A1 (it) | 2004-10-26 | 2004-10-26 | Derivati solfonammidici antagonisti del recettore dei vanilloidi trpv1 |
| ITMI2004A002042 | 2004-10-26 | ||
| PCT/EP2005/011206 WO2006045498A1 (en) | 2004-10-26 | 2005-10-18 | Sulfonamido compounds that antagonise the vanilloid trpv1 receptor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008517884A JP2008517884A (ja) | 2008-05-29 |
| JP2008517884A5 true JP2008517884A5 (enExample) | 2008-12-25 |
| JP5080260B2 JP5080260B2 (ja) | 2012-11-21 |
Family
ID=35501228
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007537190A Expired - Fee Related JP5080260B2 (ja) | 2004-10-26 | 2005-10-18 | バニロイドｔｒｐｖ１受容体に拮抗するスルホンアミド化合物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7579378B2 (enExample) |
| EP (1) | EP1805138B1 (enExample) |
| JP (1) | JP5080260B2 (enExample) |
| AT (1) | ATE389634T1 (enExample) |
| DE (1) | DE602005005512T2 (enExample) |
| ES (1) | ES2303275T3 (enExample) |
| IT (1) | ITMI20042042A1 (enExample) |
| WO (1) | WO2006045498A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2006225496A1 (en) * | 2005-03-19 | 2006-09-28 | Amorepacific Corporation | Novel compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and pharmaceutical compositions containing the same |
| WO2009081222A1 (en) | 2007-12-21 | 2009-07-02 | Glenmark Pharmaceuticals, S.A. | Substituted tricyclic pyridine or pyrimidine vanilloid receptor ligands |
| CN106146362B (zh) * | 2015-04-15 | 2018-04-03 | 南京理工大学 | 一种合成c‑7280948的方法 |
| CN107759477A (zh) * | 2017-11-20 | 2018-03-06 | 阿里化学(常州)有限公司 | 一种对硝基苯乙胺盐酸盐的生产制备方法 |
| EP4074317A1 (en) | 2021-04-14 | 2022-10-19 | Bayer AG | Phosphorus derivatives as novel sos1 inhibitors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0693386B1 (en) | 1994-07-21 | 1997-02-05 | Nippon Paper Industries Co., Ltd. | Aminobenzenesulfonamide derivatives as colour-developers for thermosensitive recording materials |
| EP1311478B1 (en) * | 2000-08-21 | 2006-06-07 | Pacific Corporation | Novel (thio)urea compounds and the pharmaceutical compositions containing the same |
| EP1303483B1 (en) * | 2000-08-21 | 2008-04-23 | Pacific Corporation | Novel thiourea derivatives and the pharmaceutical compositions containing the same |
| EP1395548A1 (en) * | 2001-02-26 | 2004-03-10 | 4Sc Ag | Derivatives of diphenylurea, diphenyloxalic acid diamide and diphenylsulfuric acid diamide and their use as medicaments |
-
2004
- 2004-10-26 IT IT002042A patent/ITMI20042042A1/it unknown
-
2005
- 2005-10-18 DE DE602005005512T patent/DE602005005512T2/de not_active Expired - Lifetime
- 2005-10-18 AT AT05796943T patent/ATE389634T1/de not_active IP Right Cessation
- 2005-10-18 US US11/577,857 patent/US7579378B2/en not_active Expired - Fee Related
- 2005-10-18 JP JP2007537190A patent/JP5080260B2/ja not_active Expired - Fee Related
- 2005-10-18 WO PCT/EP2005/011206 patent/WO2006045498A1/en not_active Ceased
- 2005-10-18 ES ES05796943T patent/ES2303275T3/es not_active Expired - Lifetime
- 2005-10-18 EP EP05796943A patent/EP1805138B1/en not_active Expired - Lifetime
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