JP2008515565A5 - - Google Patents
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- JP2008515565A5 JP2008515565A5 JP2007535895A JP2007535895A JP2008515565A5 JP 2008515565 A5 JP2008515565 A5 JP 2008515565A5 JP 2007535895 A JP2007535895 A JP 2007535895A JP 2007535895 A JP2007535895 A JP 2007535895A JP 2008515565 A5 JP2008515565 A5 JP 2008515565A5
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- 210000001519 tissue Anatomy 0.000 claims 54
- 239000000203 mixture Substances 0.000 claims 52
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 45
- 238000000034 method Methods 0.000 claims 42
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 23
- 239000000243 solution Substances 0.000 claims 20
- 239000000758 substrate Substances 0.000 claims 20
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 18
- 238000006073 displacement reaction Methods 0.000 claims 18
- 239000003795 chemical substances by application Substances 0.000 claims 15
- 239000011159 matrix material Substances 0.000 claims 13
- 239000000126 substance Substances 0.000 claims 8
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims 6
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 6
- 241000251539 Vertebrata <Metazoa> Species 0.000 claims 5
- 210000000056 organ Anatomy 0.000 claims 5
- 229920001612 Hydroxyethyl starch Polymers 0.000 claims 4
- 229920000881 Modified starch Polymers 0.000 claims 4
- 239000002202 Polyethylene glycol Substances 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 4
- 210000004195 gingiva Anatomy 0.000 claims 4
- 229940050526 hydroxyethylstarch Drugs 0.000 claims 4
- 230000001678 irradiating effect Effects 0.000 claims 4
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims 4
- 235000019426 modified starch Nutrition 0.000 claims 4
- 229920001223 polyethylene glycol Polymers 0.000 claims 4
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 4
- 235000019422 polyvinyl alcohol Nutrition 0.000 claims 4
- 150000005846 sugar alcohols Chemical class 0.000 claims 4
- 210000004207 dermis Anatomy 0.000 claims 3
- 150000002016 disaccharides Chemical class 0.000 claims 3
- 150000004676 glycans Chemical class 0.000 claims 3
- 210000003041 ligament Anatomy 0.000 claims 3
- 239000000463 material Substances 0.000 claims 3
- 150000002772 monosaccharides Chemical class 0.000 claims 3
- 229920001542 oligosaccharide Polymers 0.000 claims 3
- 150000002482 oligosaccharides Chemical class 0.000 claims 3
- 229920001282 polysaccharide Polymers 0.000 claims 3
- 239000005017 polysaccharide Substances 0.000 claims 3
- 210000002435 tendon Anatomy 0.000 claims 3
- 210000000626 ureter Anatomy 0.000 claims 3
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 2
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 claims 2
- 241000283690 Bos taurus Species 0.000 claims 2
- 229920001287 Chondroitin sulfate Polymers 0.000 claims 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims 2
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 2
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims 2
- 239000004386 Erythritol Substances 0.000 claims 2
- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 claims 2
- 229940123457 Free radical scavenger Drugs 0.000 claims 2
- AYRXSINWFIIFAE-SCLMCMATSA-N Isomaltose Natural products OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O)[C@@H](O)[C@@H](O)[C@@H]1O AYRXSINWFIIFAE-SCLMCMATSA-N 0.000 claims 2
- 229920002774 Maltodextrin Polymers 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 229930195725 Mannitol Natural products 0.000 claims 2
- 108010009736 Protein Hydrolysates Proteins 0.000 claims 2
- 102000016611 Proteoglycans Human genes 0.000 claims 2
- 108010067787 Proteoglycans Proteins 0.000 claims 2
- 229920002472 Starch Polymers 0.000 claims 2
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims 2
- 210000003815 abdominal wall Anatomy 0.000 claims 2
- 210000005068 bladder tissue Anatomy 0.000 claims 2
- 229940059329 chondroitin sulfate Drugs 0.000 claims 2
- 150000003999 cyclitols Chemical class 0.000 claims 2
- 210000001951 dura mater Anatomy 0.000 claims 2
- 235000019414 erythritol Nutrition 0.000 claims 2
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 claims 2
- 229940009714 erythritol Drugs 0.000 claims 2
- 210000003709 heart valve Anatomy 0.000 claims 2
- 229920002674 hyaluronan Polymers 0.000 claims 2
- 229960003160 hyaluronic acid Drugs 0.000 claims 2
- 230000000968 intestinal effect Effects 0.000 claims 2
- DLRVVLDZNNYCBX-RTPHMHGBSA-N isomaltose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)C(O)O1 DLRVVLDZNNYCBX-RTPHMHGBSA-N 0.000 claims 2
- 239000000832 lactitol Substances 0.000 claims 2
- 235000010448 lactitol Nutrition 0.000 claims 2
- VQHSOMBJVWLPSR-JVCRWLNRSA-N lactitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-JVCRWLNRSA-N 0.000 claims 2
- 229960003451 lactitol Drugs 0.000 claims 2
- 239000000845 maltitol Substances 0.000 claims 2
- 235000010449 maltitol Nutrition 0.000 claims 2
- VQHSOMBJVWLPSR-WUJBLJFYSA-N maltitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-WUJBLJFYSA-N 0.000 claims 2
- 229940035436 maltitol Drugs 0.000 claims 2
- 239000000594 mannitol Substances 0.000 claims 2
- 235000010355 mannitol Nutrition 0.000 claims 2
- 229960001855 mannitol Drugs 0.000 claims 2
- 210000000944 nerve tissue Anatomy 0.000 claims 2
- 210000005059 placental tissue Anatomy 0.000 claims 2
- 229920000223 polyglycerol Polymers 0.000 claims 2
- 239000003531 protein hydrolysate Substances 0.000 claims 2
- 230000005855 radiation Effects 0.000 claims 2
- 239000002516 radical scavenger Substances 0.000 claims 2
- HEBKCHPVOIAQTA-ZXFHETKHSA-N ribitol Chemical compound OC[C@H](O)[C@H](O)[C@H](O)CO HEBKCHPVOIAQTA-ZXFHETKHSA-N 0.000 claims 2
- 239000000600 sorbitol Substances 0.000 claims 2
- 229960002920 sorbitol Drugs 0.000 claims 2
- 235000010356 sorbitol Nutrition 0.000 claims 2
- 235000019698 starch Nutrition 0.000 claims 2
- 239000008107 starch Substances 0.000 claims 2
- 229930003799 tocopherol Natural products 0.000 claims 2
- 239000011732 tocopherol Substances 0.000 claims 2
- 235000019149 tocopherols Nutrition 0.000 claims 2
- 210000003954 umbilical cord Anatomy 0.000 claims 2
- 239000000811 xylitol Substances 0.000 claims 2
- 235000010447 xylitol Nutrition 0.000 claims 2
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims 2
- 229960002675 xylitol Drugs 0.000 claims 2
- QUEDXNHFTDJVIY-UHFFFAOYSA-N γ-tocopherol Chemical class OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 QUEDXNHFTDJVIY-UHFFFAOYSA-N 0.000 claims 2
- 208000006735 Periostitis Diseases 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 210000001367 artery Anatomy 0.000 claims 1
- 210000000988 bone and bone Anatomy 0.000 claims 1
- 229940036811 bone meal Drugs 0.000 claims 1
- 239000002374 bone meal Substances 0.000 claims 1
- 210000000845 cartilage Anatomy 0.000 claims 1
- 230000008602 contraction Effects 0.000 claims 1
- 230000007547 defect Effects 0.000 claims 1
- 210000000188 diaphragm Anatomy 0.000 claims 1
- 238000000605 extraction Methods 0.000 claims 1
- 210000003195 fascia Anatomy 0.000 claims 1
- 238000010438 heat treatment Methods 0.000 claims 1
- 230000002427 irreversible effect Effects 0.000 claims 1
- 210000005067 joint tissue Anatomy 0.000 claims 1
- 210000002429 large intestine Anatomy 0.000 claims 1
- 230000005499 meniscus Effects 0.000 claims 1
- 210000004165 myocardium Anatomy 0.000 claims 1
- 230000001537 neural effect Effects 0.000 claims 1
- 210000003460 periosteum Anatomy 0.000 claims 1
- 210000003491 skin Anatomy 0.000 claims 1
- 210000000813 small intestine Anatomy 0.000 claims 1
- 210000002460 smooth muscle Anatomy 0.000 claims 1
- 210000002784 stomach Anatomy 0.000 claims 1
- 210000003699 striated muscle Anatomy 0.000 claims 1
- 210000003708 urethra Anatomy 0.000 claims 1
- 210000003932 urinary bladder Anatomy 0.000 claims 1
- 210000003462 vein Anatomy 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/959,780 US20060073592A1 (en) | 2004-10-06 | 2004-10-06 | Methods of storing tissue matrices |
| PCT/US2005/036433 WO2006042238A2 (en) | 2004-10-06 | 2005-10-06 | Methods of storing tissue matrices |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008515565A JP2008515565A (ja) | 2008-05-15 |
| JP2008515565A5 true JP2008515565A5 (https=) | 2008-11-27 |
Family
ID=36126049
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007535895A Pending JP2008515565A (ja) | 2004-10-06 | 2005-10-06 | 組織基質の保存法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20060073592A1 (https=) |
| EP (1) | EP1809735A4 (https=) |
| JP (1) | JP2008515565A (https=) |
| AU (1) | AU2005295039B2 (https=) |
| CA (1) | CA2582528A1 (https=) |
| WO (1) | WO2006042238A2 (https=) |
Families Citing this family (79)
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| US20100112543A1 (en) * | 2005-03-16 | 2010-05-06 | Manh-Dan Ngo | Processing soft tissue, methods and compositions related thereto |
| US7723108B2 (en) * | 2005-03-16 | 2010-05-25 | Musculoskeletal Transplant Foundation | Soft tissue processing |
| US8568761B2 (en) | 2005-07-15 | 2013-10-29 | Cormatrix Cardiovascular, Inc. | Compositions for regenerating defective or absent myocardium |
| US20070014869A1 (en) * | 2005-07-15 | 2007-01-18 | Cormatrix Cardiovascular, Inc. | Compositions for reconstruction, replacement or repair of intracardiac tissue |
| CN103173401A (zh) * | 2005-12-22 | 2013-06-26 | 简·恩尼斯 | 来自冷冻的脐带组织的活细胞 |
| US20070248575A1 (en) * | 2006-04-19 | 2007-10-25 | Jerome Connor | Bone graft composition |
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| US11504231B2 (en) | 2018-05-23 | 2022-11-22 | Corcym S.R.L. | Cardiac valve prosthesis |
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| BR102018073510A2 (pt) * | 2018-11-14 | 2020-05-26 | Edmar Maciel Lima Junior | processo de obtenção de pele de tilápia liofilizada e uso da pele de tilápia liofilizada |
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| CN111265717B (zh) * | 2020-03-04 | 2020-11-03 | 动之医学技术(上海)有限公司 | 医用套管及其制备方法 |
| MX2023000120A (es) * | 2020-06-20 | 2023-02-09 | The Steadman Clinic And Steadman Philippon Res Institute | Metodos de matriz de tendon descelularizada y usos de los mismos. |
| US12532881B2 (en) | 2020-08-19 | 2026-01-27 | Lifecell Corporation | Tissue packaging and method of using same |
| KR102719780B1 (ko) * | 2024-03-06 | 2024-10-21 | (주)시지바이오 | 무세포 진피 기질을 포함하는 저압출 조성물 및 그 제조방법 |
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|---|---|---|---|---|
| US5336616A (en) * | 1990-09-12 | 1994-08-09 | Lifecell Corporation | Method for processing and preserving collagen-based tissues for transplantation |
| JP3471967B2 (ja) * | 1995-03-28 | 2003-12-02 | カネボウ株式会社 | ハイブリッド型人工歯根 |
| US7063726B2 (en) * | 1998-06-30 | 2006-06-20 | Lifenet | Plasticized bone grafts and methods of making and using same |
| US6734018B2 (en) * | 1999-06-07 | 2004-05-11 | Lifenet | Process for decellularizing soft-tissue engineered medical implants, and decellularized soft-tissue medical implants produced |
| DE19940426A1 (de) * | 1999-08-26 | 2001-03-01 | Tutogen Medical Gmbh | Verfahren zum Dehydratisieren von biologischen Geweben zur Herstellung von Transplantat-Konserven |
| US6872357B1 (en) * | 2000-11-22 | 2005-03-29 | Quadrant Drug Delivery Limited | Formulation of preservation mixtures containing sensitive biologicals to be stabilized for ambient temperature storage by drying |
| WO2003024496A1 (en) * | 2001-09-05 | 2003-03-27 | Hans Biomed Corporation | A process for preparing a biomaterial for tissue repair |
| US20030185702A1 (en) * | 2002-02-01 | 2003-10-02 | Wilson Burgess | Methods for sterilizing tissue |
| WO2003032735A1 (en) * | 2001-10-18 | 2003-04-24 | Lifecell Corporation | Remodeling of tissues and organs |
| CA2533259C (en) * | 2003-07-21 | 2014-01-28 | Lifecell Corporation | Acellular tissue matrices made from galactose .alpha.-1,3-galactose-deficient tissue |
-
2004
- 2004-10-06 US US10/959,780 patent/US20060073592A1/en not_active Abandoned
-
2005
- 2005-10-06 EP EP05808684A patent/EP1809735A4/en not_active Withdrawn
- 2005-10-06 JP JP2007535895A patent/JP2008515565A/ja active Pending
- 2005-10-06 WO PCT/US2005/036433 patent/WO2006042238A2/en not_active Ceased
- 2005-10-06 CA CA002582528A patent/CA2582528A1/en not_active Abandoned
- 2005-10-06 AU AU2005295039A patent/AU2005295039B2/en not_active Expired
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