JP2008514586A - 新規な抗菌剤 - Google Patents

新規な抗菌剤 Download PDF

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Publication number
JP2008514586A
JP2008514586A JP2007533055A JP2007533055A JP2008514586A JP 2008514586 A JP2008514586 A JP 2008514586A JP 2007533055 A JP2007533055 A JP 2007533055A JP 2007533055 A JP2007533055 A JP 2007533055A JP 2008514586 A JP2008514586 A JP 2008514586A
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JP
Japan
Prior art keywords
polymer
residue
amino acid
residues
acid
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Pending
Application number
JP2007533055A
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English (en)
Japanese (ja)
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JP2008514586A5 (enExample
Inventor
アムラム モル,
インナ ラドジシェヴスキー,
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Technion Research and Development Foundation Ltd
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Technion Research and Development Foundation Ltd
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Application filed by Technion Research and Development Foundation Ltd filed Critical Technion Research and Development Foundation Ltd
Publication of JP2008514586A publication Critical patent/JP2008514586A/ja
Publication of JP2008514586A5 publication Critical patent/JP2008514586A5/ja
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/02Peptides of undefined number of amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23BPRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00Preservation of foods or foodstuffs, in general
    • A23B2/70Preservation of foods or foodstuffs, in general by treatment with chemicals
    • A23B2/725Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
    • A23B2/729Organic compounds; Microorganisms; Enzymes
    • A23B2/742Organic compounds containing oxygen
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23BPRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00Preservation of foods or foodstuffs, in general
    • A23B2/70Preservation of foods or foodstuffs, in general by treatment with chemicals
    • A23B2/725Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
    • A23B2/729Organic compounds; Microorganisms; Enzymes
    • A23B2/762Organic compounds containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542Carboxylic acids, e.g. a fatty acid or an amino acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0002General or multifunctional contrast agents, e.g. chelated agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723Cationic antimicrobial peptides, e.g. defensins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polyamides (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Peptides Or Proteins (AREA)
JP2007533055A 2004-09-27 2005-09-26 新規な抗菌剤 Pending JP2008514586A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61277804P 2004-09-27 2004-09-27
PCT/IL2005/001030 WO2006035431A2 (en) 2004-09-27 2005-09-26 Fatty acid modified polylysines as antimicrobial agents

Publications (2)

Publication Number Publication Date
JP2008514586A true JP2008514586A (ja) 2008-05-08
JP2008514586A5 JP2008514586A5 (enExample) 2008-10-16

Family

ID=35930003

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007533055A Pending JP2008514586A (ja) 2004-09-27 2005-09-26 新規な抗菌剤

Country Status (8)

Country Link
US (3) US7504381B2 (enExample)
EP (1) EP1793837A2 (enExample)
JP (1) JP2008514586A (enExample)
CN (1) CN101065131B (enExample)
AU (1) AU2005288519A1 (enExample)
CA (1) CA2581883A1 (enExample)
MX (1) MX2007003608A (enExample)
WO (1) WO2006035431A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010154765A (ja) * 2008-12-26 2010-07-15 Hiroshi Kaino 健康食材
JP2010279329A (ja) * 2009-06-08 2010-12-16 Hiroshi Kaino 健康食材

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060013862A1 (en) * 2004-07-19 2006-01-19 Held Jerry M Onychomycosis: a new process for cure
US7915223B2 (en) 2004-09-27 2011-03-29 Technion Research & Development Foundation Ltd. Antimicrobial agents
EP2390255B1 (en) * 2006-04-03 2016-07-13 Technion Research & Development Foundation Ltd. Novel aminoglycosides and uses thereof in the treatment of genetic disorders
KR101487719B1 (ko) 2006-05-16 2015-01-29 페르가뭄 아베 개선된 항미생물성 펩타이드
EP2092071B1 (en) * 2006-12-14 2014-11-12 Technion Research & Development Foundation Ltd. Compositions and methods for concentrating and depleting microorganisms
CN101622271B (zh) * 2007-01-16 2014-08-27 加利福尼亚大学董事会 抗微生物肽
US20080214417A1 (en) * 2007-02-07 2008-09-04 University Of Waterloo Lubricant for wear testing of joint replacements and associated materials
FR2913335B1 (fr) * 2007-03-06 2009-06-05 Michel Geffard Utilisation de conjugues d'acides gras et de poly-l-lysine pour lutter contre des microorganismes pathogenes.
WO2008132737A1 (en) * 2007-04-30 2008-11-06 Technion Research & Development Foundation Ltd. Novel antimicrobial agents
WO2008132738A2 (en) * 2007-04-30 2008-11-06 Technion Research & Development Foundation Ltd. Anticancerous polymeric agents
AU2009269702B2 (en) 2008-07-11 2016-07-21 Universal Biosensors Pty Ltd Enhanced immunoassay sensor
CZ301719B6 (cs) * 2009-02-12 2010-06-02 Ústav organické chemie a biochemie Akademie ved Ceské republiky, v. v. i. Antimikrobiální peptidy
RU2400069C1 (ru) * 2009-06-11 2010-09-27 Галина Ивановна Эль-Регистан Способ защиты материалов от микробного разрушения
WO2011016043A2 (en) 2009-08-06 2011-02-10 Technion Research & Development Foundation Ltd. Antibiotic drug delivery and potentiation
US9264184B2 (en) * 2009-10-30 2016-02-16 Sony Corporation Coordinated signaling of scheduling information for uplink and downlink communications
US20120305482A1 (en) * 2010-02-09 2012-12-06 Exthera Medical, Llc Removal of virulence factors through extracorporeal therapy
WO2012081944A2 (en) * 2010-12-16 2012-06-21 Republic Of Korea(Management : Rural Development Administration) Dental membrane and method of manufacturing the same
US20120219682A1 (en) * 2011-02-28 2012-08-30 Frank Monteleone Antimicrobial compositions within antioxidant solutions used to protect whole protein foods
BR112014011868A2 (pt) * 2011-11-16 2017-05-16 3M Innovative Properties Co composições corantes poliméricas e métodos de uso
RU2666605C2 (ru) * 2013-05-01 2018-09-11 Неокули Пти Лтд Способы лечения бактериальных инфекций
BR112018076309A8 (pt) * 2016-06-17 2022-06-28 Univ Erasmus Med Ct Rotterdam Compostos de geminóide e seus usos
CN112386563A (zh) * 2019-08-12 2021-02-23 湖南早晨纳米机器人有限公司 微纳米载药机器人及其制备方法
CN113563261B (zh) * 2021-07-28 2023-09-01 西北大学 一种水溶性多脲抗菌分子及其制备方法和应用
CN114533679B (zh) * 2022-01-28 2023-03-14 马超锋 一种磺胺氯哒嗪缓释纳米胶粒及其制备方法
CN119837867B (zh) * 2025-01-13 2025-10-03 中国水产科学研究院长江水产研究所 防耐药复方氟苯尼考与盐酸小檗碱粉剂的制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003035677A2 (en) * 2001-08-17 2003-05-01 University Of Bern Antimicrobial peptides from the venom of the spider cupiennius salei

Family Cites Families (12)

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US5965525A (en) * 1992-03-19 1999-10-12 Eli Lilly And Company Cyclic peptide antifungal agents
AU7935494A (en) * 1993-10-25 1995-05-22 National Research Council Of Canada Bivalent thrombin inhibitors
US6057291A (en) * 1995-06-02 2000-05-02 University Of British Columbia Antimicrobial cationic peptides
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US6571790B1 (en) 1997-05-12 2003-06-03 Robert E. Weinstein Method and device for organizing and coordinating the combined use of liquid medications for continuous nebulization for the treatment of respiratory disorders
US6548048B1 (en) * 1998-04-28 2003-04-15 Amersham Health As Lipopeptide stabilized microbubbles as diagnostic/therapeutic agents
HRP20010119B1 (hr) 1998-08-18 2008-05-31 The Regents Of The University Of California Sprječavanje stvaranja sluzi u dišnim putevima primjenom antagonista egf-r
GB9928323D0 (en) * 1999-11-30 2000-01-26 Cyclacel Ltd Peptides
US6637430B1 (en) 2000-06-16 2003-10-28 Ponwell Enterprises Limited Respiratory delivery system with power/medicament recharge assembly
FR2813080B1 (fr) * 2000-08-17 2002-11-29 Stago Diagnostica Peptides anti-heparine
US6652323B2 (en) 2002-02-19 2003-11-25 Leon M. Yanda Precision parking device
JP2007512234A (ja) * 2003-10-17 2007-05-17 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ 治療活性を有する修飾ポリペプチド及びその使用方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003035677A2 (en) * 2001-08-17 2003-05-01 University Of Bern Antimicrobial peptides from the venom of the spider cupiennius salei

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010154765A (ja) * 2008-12-26 2010-07-15 Hiroshi Kaino 健康食材
JP2010279329A (ja) * 2009-06-08 2010-12-16 Hiroshi Kaino 健康食材

Also Published As

Publication number Publication date
AU2005288519A1 (en) 2006-04-06
CN101065131B (zh) 2012-10-24
WO2006035431A2 (en) 2006-04-06
US20120295837A1 (en) 2012-11-22
CA2581883A1 (en) 2006-04-06
US7504381B2 (en) 2009-03-17
US20060074021A1 (en) 2006-04-06
CN101065131A (zh) 2007-10-31
EP1793837A2 (en) 2007-06-13
US20100278807A1 (en) 2010-11-04
WO2006035431A3 (en) 2007-05-24
MX2007003608A (es) 2007-08-14

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