JP2008512399A - 医薬組成物およびアルギナーゼを用いる肝炎の処置方法 - Google Patents

医薬組成物およびアルギナーゼを用いる肝炎の処置方法 Download PDF

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JP2008512399A
JP2008512399A JP2007530572A JP2007530572A JP2008512399A JP 2008512399 A JP2008512399 A JP 2008512399A JP 2007530572 A JP2007530572 A JP 2007530572A JP 2007530572 A JP2007530572 A JP 2007530572A JP 2008512399 A JP2008512399 A JP 2008512399A
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Prior art keywords
arginase
pharmaceutical composition
enzyme
composition according
use according
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Pending
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JP2007530572A
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Japanese (ja)
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JP2008512399A5 (OSRAM
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寧 民 鄭
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康達医藥科技有限公司
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Publication of JP2008512399A5 publication Critical patent/JP2008512399A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/50—Hydrolases (3) acting on carbon-nitrogen bonds, other than peptide bonds (3.5), e.g. asparaginase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2007530572A 2004-09-08 2005-09-06 医薬組成物およびアルギナーゼを用いる肝炎の処置方法 Pending JP2008512399A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CNA2004100768544A CN1745847A (zh) 2004-09-08 2004-09-08 用精氨酸酶治疗肝炎的药物组合物和方法
PCT/CN2005/001411 WO2006026915A1 (fr) 2004-09-08 2005-09-06 Composition pharmaceutique et methode de traitement de l'hepatite avec des arginases

Publications (2)

Publication Number Publication Date
JP2008512399A true JP2008512399A (ja) 2008-04-24
JP2008512399A5 JP2008512399A5 (OSRAM) 2008-10-02

Family

ID=36036072

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007530572A Pending JP2008512399A (ja) 2004-09-08 2005-09-06 医薬組成物およびアルギナーゼを用いる肝炎の処置方法

Country Status (6)

Country Link
US (1) US20080299638A1 (OSRAM)
EP (1) EP1803465A4 (OSRAM)
JP (1) JP2008512399A (OSRAM)
KR (1) KR20070100875A (OSRAM)
CN (1) CN1745847A (OSRAM)
WO (1) WO2006026915A1 (OSRAM)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3778885T (pt) 2008-10-31 2023-05-31 Aerase Inc Composições de arginases humanas modificadas e métodos para o tratamento do cancro
WO2010124547A1 (en) * 2009-03-26 2010-11-04 The Hong Kong Polytechnic University Site-directed pegylation of arginases and the use thereof as anti-cancer and anti-viral agents
CN103184209B (zh) * 2011-12-27 2015-09-16 拜奥生物科技(上海)有限公司 人精氨酸酶和聚乙二醇化人精氨酸酶及其应用
ES2897635T3 (es) 2014-04-29 2022-03-02 Bio Cancer Treat International Ltd Métodos y composiciones para modular el sistema inmunológico con la arginasa I
BR112019002458A2 (pt) 2016-08-08 2019-05-14 Aerase, Inc. composições e métodos para tratar câncer com depleção de arginina e agentes imuno-oncológicos
US11717562B2 (en) 2017-12-05 2023-08-08 Aerase, Inc. Method and composition for treating arginase 1 deficiency
JP7667931B2 (ja) 2018-10-19 2025-04-24 イメディカ・ファーマ・アー・ベー Gamt欠損症の治療のためのアルギニン枯渇療法
CA3149592A1 (en) 2019-08-30 2021-03-04 Scott W. Rowlinson Methods for production of human recombinant arginase 1 and uses thereof
CN116056720A (zh) * 2020-04-17 2023-05-02 香港商康达医药科技有限公司 使用精胺酸酶治疗病毒感染的方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004000349A1 (en) * 2002-06-20 2003-12-31 Bio-Cancer Treatment International Limited Pharmaceutical preparation and method of treatment of human malignancies with arginine deprivation
WO2004001048A1 (en) * 2002-06-20 2003-12-31 Bio-Cancer Treatment International Limited Pharmaceutical composition and method of treatment of human malignancies with arginine deprivation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1059127C (zh) * 1995-07-19 2000-12-06 郝文学 治疗肝病的药物“疏肝酶”的制法
US5780286A (en) * 1996-03-14 1998-07-14 Smithkline Beecham Corporation Arginase II
US5851985A (en) * 1996-08-16 1998-12-22 Tepic; Slobodan Treatment of tumors by arginine deprivation
US6183738B1 (en) * 1997-05-12 2001-02-06 Phoenix Pharamacologics, Inc. Modified arginine deiminase

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004000349A1 (en) * 2002-06-20 2003-12-31 Bio-Cancer Treatment International Limited Pharmaceutical preparation and method of treatment of human malignancies with arginine deprivation
WO2004001048A1 (en) * 2002-06-20 2003-12-31 Bio-Cancer Treatment International Limited Pharmaceutical composition and method of treatment of human malignancies with arginine deprivation

Also Published As

Publication number Publication date
EP1803465A1 (en) 2007-07-04
WO2006026915A1 (fr) 2006-03-16
CN1745847A (zh) 2006-03-15
US20080299638A1 (en) 2008-12-04
KR20070100875A (ko) 2007-10-12
EP1803465A4 (en) 2009-08-12

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