JP2008511008A5 - - Google Patents
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- JP2008511008A5 JP2008511008A5 JP2007530178A JP2007530178A JP2008511008A5 JP 2008511008 A5 JP2008511008 A5 JP 2008511008A5 JP 2007530178 A JP2007530178 A JP 2007530178A JP 2007530178 A JP2007530178 A JP 2007530178A JP 2008511008 A5 JP2008511008 A5 JP 2008511008A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- nanotube
- constraining
- sensor
- sensor system
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000002071 nanotube Substances 0.000 claims 41
- 102000040430 polynucleotide Human genes 0.000 claims 21
- 108091033319 polynucleotide Proteins 0.000 claims 21
- 239000002157 polynucleotide Substances 0.000 claims 21
- 238000001514 detection method Methods 0.000 claims 19
- 125000005647 linker group Chemical group 0.000 claims 15
- 238000000034 method Methods 0.000 claims 14
- 239000000758 substrate Substances 0.000 claims 14
- 108020004414 DNA Proteins 0.000 claims 10
- 102000053602 DNA Human genes 0.000 claims 10
- 238000005259 measurement Methods 0.000 claims 10
- 108020004682 Single-Stranded DNA Proteins 0.000 claims 9
- 230000027455 binding Effects 0.000 claims 9
- 108010001857 Cell Surface Receptors Proteins 0.000 claims 4
- 230000000295 complement effect Effects 0.000 claims 4
- 102000006240 membrane receptors Human genes 0.000 claims 4
- 239000000523 sample Substances 0.000 claims 4
- 239000000243 solution Substances 0.000 claims 4
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 3
- 238000000151 deposition Methods 0.000 claims 3
- 239000002086 nanomaterial Substances 0.000 claims 3
- 102000005962 receptors Human genes 0.000 claims 3
- 239000002109 single walled nanotube Substances 0.000 claims 3
- 229910052582 BN Inorganic materials 0.000 claims 2
- 108010069941 DNA receptor Proteins 0.000 claims 2
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 229920001222 biopolymer Polymers 0.000 claims 2
- 229910052799 carbon Inorganic materials 0.000 claims 2
- 239000003446 ligand Substances 0.000 claims 2
- 229910052751 metal Inorganic materials 0.000 claims 2
- 239000002184 metal Substances 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 230000001737 promoting effect Effects 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 108010032595 Antibody Binding Sites Proteins 0.000 claims 1
- ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 claims 1
- PZNSFCLAULLKQX-UHFFFAOYSA-N Boron nitride Chemical compound N#B PZNSFCLAULLKQX-UHFFFAOYSA-N 0.000 claims 1
- 229910002601 GaN Inorganic materials 0.000 claims 1
- JMASRVWKEDWRBT-UHFFFAOYSA-N Gallium nitride Chemical compound [Ga]#N JMASRVWKEDWRBT-UHFFFAOYSA-N 0.000 claims 1
- GPXJNWSHGFTCBW-UHFFFAOYSA-N Indium phosphide Chemical compound [In]#P GPXJNWSHGFTCBW-UHFFFAOYSA-N 0.000 claims 1
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
- 108091034117 Oligonucleotide Proteins 0.000 claims 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims 1
- 108091023040 Transcription factor Proteins 0.000 claims 1
- 102000040945 Transcription factor Human genes 0.000 claims 1
- PPWPWBNSKBDSPK-UHFFFAOYSA-N [B].[C] Chemical compound [B].[C] PPWPWBNSKBDSPK-UHFFFAOYSA-N 0.000 claims 1
- 230000025845 adhesion to host Effects 0.000 claims 1
- 150000001491 aromatic compounds Chemical class 0.000 claims 1
- 230000000903 blocking effect Effects 0.000 claims 1
- 229910052796 boron Inorganic materials 0.000 claims 1
- 239000002041 carbon nanotube Substances 0.000 claims 1
- 229910021393 carbon nanotube Inorganic materials 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 239000002299 complementary DNA Substances 0.000 claims 1
- 229920001940 conductive polymer Polymers 0.000 claims 1
- 239000002079 double walled nanotube Substances 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- 230000012202 endocytosis Effects 0.000 claims 1
- 230000005669 field effect Effects 0.000 claims 1
- 229910052732 germanium Inorganic materials 0.000 claims 1
- GNPVGFCGXDBREM-UHFFFAOYSA-N germanium atom Chemical compound [Ge] GNPVGFCGXDBREM-UHFFFAOYSA-N 0.000 claims 1
- 238000009396 hybridization Methods 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 210000004962 mammalian cell Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- CWQXQMHSOZUFJS-UHFFFAOYSA-N molybdenum disulfide Chemical compound S=[Mo]=S CWQXQMHSOZUFJS-UHFFFAOYSA-N 0.000 claims 1
- 229910052982 molybdenum disulfide Inorganic materials 0.000 claims 1
- 239000002048 multi walled nanotube Substances 0.000 claims 1
- 238000001338 self-assembly Methods 0.000 claims 1
- 229910052710 silicon Inorganic materials 0.000 claims 1
- 239000010703 silicon Substances 0.000 claims 1
- 229910052709 silver Inorganic materials 0.000 claims 1
- 239000004332 silver Substances 0.000 claims 1
- 230000009870 specific binding Effects 0.000 claims 1
- 229920002994 synthetic fiber Polymers 0.000 claims 1
- 229920001059 synthetic polymer Polymers 0.000 claims 1
- 239000012085 test solution Substances 0.000 claims 1
- 238000013518 transcription Methods 0.000 claims 1
- 230000035897 transcription Effects 0.000 claims 1
- 210000002845 virion Anatomy 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 239000011787 zinc oxide Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60429304P | 2004-08-24 | 2004-08-24 | |
| US62960404P | 2004-11-19 | 2004-11-19 | |
| PCT/US2005/030487 WO2006024023A2 (en) | 2004-08-24 | 2005-08-24 | Nanotube sensor devices for dna detection |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012175154A Division JP5743974B2 (ja) | 2004-08-24 | 2012-08-07 | Dna検出用ナノチューブセンサー装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008511008A JP2008511008A (ja) | 2008-04-10 |
| JP2008511008A5 true JP2008511008A5 (enExample) | 2008-10-09 |
Family
ID=35968333
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007530178A Pending JP2008511008A (ja) | 2004-08-24 | 2005-08-24 | Dna検出用ナノチューブセンサー装置 |
| JP2012175154A Expired - Fee Related JP5743974B2 (ja) | 2004-08-24 | 2012-08-07 | Dna検出用ナノチューブセンサー装置 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012175154A Expired - Fee Related JP5743974B2 (ja) | 2004-08-24 | 2012-08-07 | Dna検出用ナノチューブセンサー装置 |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP1781771A2 (enExample) |
| JP (2) | JP2008511008A (enExample) |
| WO (1) | WO2006024023A2 (enExample) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8154093B2 (en) | 2002-01-16 | 2012-04-10 | Nanomix, Inc. | Nano-electronic sensors for chemical and biological analytes, including capacitance and bio-membrane devices |
| US7948041B2 (en) | 2005-05-19 | 2011-05-24 | Nanomix, Inc. | Sensor having a thin-film inhibition layer |
| US8052932B2 (en) * | 2006-12-22 | 2011-11-08 | Research Triangle Institute | Polymer nanofiber-based electronic nose |
| PT1885176T (pt) | 2005-05-27 | 2016-11-28 | Monsanto Technology Llc | Evento mon89788 de soja e métodos para a sua deteção |
| EP1999277B1 (en) * | 2006-03-17 | 2015-07-08 | The Government of the United States of America, as represented by The Department of Health and Human Services | Apparatus for biosensor microarrays based on carbon nanotube transistors having biological probe materials, method for its production and method of electronically detecting a biological target material |
| JP2009532064A (ja) * | 2006-04-04 | 2009-09-10 | ナノミックス・インコーポレーテッド | 被検体増幅とレポーターを用いる生体分子のナノ電子的検出 |
| KR100842886B1 (ko) * | 2006-04-04 | 2008-07-02 | 재단법인서울대학교산학협력재단 | 나노선을 이용한 식품 첨가물 l-글루타민산나트륨 검출용바이오센서 및 이의 제조 방법 |
| JP5513883B2 (ja) | 2006-05-26 | 2014-06-04 | モンサント テクノロジー エルエルシー | トランスジェニック事象mon89034に対応するトウモロコシ植物および種子ならびにそれらを検出および使用するための方法 |
| EP2054525A1 (en) * | 2006-07-27 | 2009-05-06 | Koninklijke Philips Electronics N.V. | Device for molecular diagnosis |
| EP2210093A4 (en) * | 2007-10-01 | 2012-12-05 | Univ Southern California | METHODS OF USING AND CONSTRUCTING NANOCAPTOR PLATFORMS |
| CN101939437A (zh) | 2008-02-15 | 2011-01-05 | 孟山都技术公司 | 对应于转基因事件mon87769的大豆植物和种子及其检测方法 |
| CN102586236B (zh) | 2008-02-29 | 2014-10-15 | 孟山都技术公司 | 玉米植物事件mon87460以及用于其检测的组合物和方法 |
| JP5767585B2 (ja) | 2008-09-29 | 2015-08-19 | モンサント テクノロジー エルエルシー | 大豆遺伝子組換え事象mon87705およびその検出方法 |
| WO2010039941A2 (en) | 2008-10-02 | 2010-04-08 | University Of New Haven | Bionanosensor detection device |
| WO2013154750A1 (en) | 2012-04-10 | 2013-10-17 | The Trustees Of Columbia Unversity In The City Of New York | Systems and methods for biological ion channel interfaces |
| US8106428B2 (en) | 2009-03-03 | 2012-01-31 | Board Of Regents, The University Of Texas System | Nano-scale bridge biosensors |
| EP2462051A4 (en) | 2009-08-07 | 2013-06-26 | Nanomix Inc | MAGNETIC CARBON NANOTUBES BASED BIO RECOGNITION |
| US8519489B2 (en) * | 2009-08-26 | 2013-08-27 | Indian Institute Of Technology Madras | Method and apparatus for tunable electrical conductivity |
| RU2425887C1 (ru) * | 2010-01-14 | 2011-08-10 | Государственное образовательное учреждение высшего профессионального образования "Российский университет дружбы народов" (РУДН) | Способ маркирования биообъектов в водном растворе |
| MX2012014066A (es) | 2010-06-04 | 2013-01-24 | Monsanto Technology Llc | Evento de brassica transgenica mon 88302 y metodos para su uso. |
| US9880126B2 (en) | 2010-09-24 | 2018-01-30 | Ajou University Industry-Academic Cooperation Foundation | Biosensor based on carbon nanotube-electric field effect transistor and method for producing the same |
| MX346994B (es) | 2010-10-12 | 2017-04-06 | Monsanto Technology Llc | Planta y semilla de soja correspondiente al evento transgénico mon87712 y métodos para su detección. |
| EP3444600B1 (en) | 2011-01-11 | 2020-05-13 | The Trustees of Columbia University in the City of New York | System and methods for single-molecule detection using nanotubes |
| CN103380369B (zh) | 2011-02-23 | 2016-12-28 | 纽约市哥伦比亚大学理事会 | 使用纳米孔进行单分子检测的系统和方法 |
| CA2835194A1 (en) * | 2011-05-05 | 2012-11-08 | Daktari Diagnostics, Inc. | Conductive patterns and methods for making conductive patterns |
| JP6223332B2 (ja) | 2011-06-30 | 2017-11-01 | モンサント テクノロジー エルエルシー | 形質転換事象kk179−2に対応するアルファルファ植物および種子、ならびにその検出方法 |
| JP5825095B2 (ja) * | 2011-12-26 | 2015-12-02 | 日本精工株式会社 | 標的物質検出バイオセンサー |
| WO2013158280A1 (en) | 2012-04-20 | 2013-10-24 | The Trustees Of Columbia University In The City Of New York | Systems and methods for single-molecule nucleic-acid assay platforms |
| GB201306097D0 (en) * | 2013-04-04 | 2013-05-22 | Isis Innovation | Sensor |
| FI130841B1 (en) | 2013-05-29 | 2024-04-18 | Csir | A channel transistor and a gas detector comprising multiple channel transistors |
| EP3026014A4 (en) * | 2013-07-25 | 2017-03-29 | Toray Industries, Inc. | Carbon nanotube composite, semiconductor device, and sensor using same |
| WO2015053998A1 (en) | 2013-10-09 | 2015-04-16 | Monsanto Technology Llc | Transgenic corn event mon87403 and methods for detection thereof |
| US11484560B2 (en) | 2014-11-14 | 2022-11-01 | Basf Plant Science Company Gmbh | Stabilising fatty acid compositions |
| CN104597082B (zh) * | 2015-01-23 | 2017-02-22 | 清华大学 | 基于二维材料的杂化分级结构敏感薄膜传感器件制备方法 |
| CN104923777A (zh) * | 2015-03-18 | 2015-09-23 | 华南理工大学 | 一种高耐盐性金属纳米粒子组装体及其制备方法 |
| US10999986B2 (en) | 2015-06-05 | 2021-05-11 | International Rice Research Institute | Increasing hybrid seed production through higher outcrossing rate in cytoplasmic male sterile rice and related materials and methods |
| WO2017033922A1 (ja) * | 2015-08-24 | 2017-03-02 | 国立大学法人 東京大学 | 電界効果トランジスタを用いた目的物質の検出方法 |
| KR101663910B1 (ko) * | 2015-09-01 | 2016-10-07 | 고려대학교 산학협력단 | 산화아연 나노와이어 검출용 센서 및 이를 이용한 수계 중 산화아연 나노와이어 검출방법 |
| WO2017173042A2 (en) * | 2016-03-30 | 2017-10-05 | Khalid Waqas | Nanostructure array based sensors for electrochemical sensing, capacitive sensing and field-emission sensing |
| JP6949397B2 (ja) * | 2016-08-31 | 2021-10-13 | 国立大学法人大阪大学 | 標的物質の電気的定量方法、定量システム及び試薬 |
| JP2018036154A (ja) * | 2016-08-31 | 2018-03-08 | 国立大学法人大阪大学 | 標的物質の電気的検出方法、定量方法、検出システム、定量システム及び試薬 |
| CN106841351B (zh) * | 2017-02-15 | 2019-07-19 | 暨南大学 | 一种二硫化钼纳米片电化学传感器及其制备方法与应用 |
| WO2018224861A1 (en) | 2017-06-07 | 2018-12-13 | International Rice Research Institute | Increasing hybrid seed production through higher outcrossing rate in cytoplasmic male sterile gramineae plants and related materials and methods |
| JP2020537131A (ja) * | 2017-10-10 | 2020-12-17 | サーモ エレクトロン サイエンティフィック インストルメンツ リミテッド ライアビリティ カンパニー | 分子相互作用を検知するためのカーボンナノチューブベースのデバイス |
| US10957626B2 (en) * | 2017-12-19 | 2021-03-23 | Thermo Electron Scientific Instruments Llc | Sensor device with carbon nanotube sensor positioned on first and second substrates |
| US11846622B2 (en) | 2018-03-12 | 2023-12-19 | The Trustees Of The University Of Pennsylvania | Multiplexed detection of toxins using graphene-based aptasensors |
| JP6876661B2 (ja) * | 2018-09-13 | 2021-05-26 | 株式会社東芝 | 有機物プローブ及び分子検出装置 |
| WO2022038536A1 (en) | 2020-08-18 | 2022-02-24 | International Rice Research Institute | Methods of increasing outcrossing rates in gramineae |
| WO2022119471A1 (en) * | 2020-12-04 | 2022-06-09 | National University Of Science And Technology "Misis" | Field effect nanosized electrical potential sensor |
| KR20250080539A (ko) * | 2023-11-28 | 2025-06-05 | 순천향대학교 산학협력단 | 엔도뉴클레아제를 선택적으로 검출하기 위한 바이오 센서용 전계효과 트랜지스터, 이를 포함하는 바이오 센서 및 이의 제조방법 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3513168A1 (de) * | 1985-04-12 | 1986-10-16 | Thomas 8000 München Dandekar | Biosensor bestehend aus einem halbleiter auf silizium oder kohlenstoffbasis (elektronischer teil) und nukleinbasen (od. anderen biol. monomeren) |
| EP0213825A3 (en) * | 1985-08-22 | 1989-04-26 | Molecular Devices Corporation | Multiple chemically modulated capacitance |
| US4963478A (en) * | 1988-07-05 | 1990-10-16 | Immucor, Inc. | Article for preforming immunological assays utilizing organic dyes and method for producing and utilizing same |
| CA2121797A1 (en) * | 1991-10-21 | 1993-04-29 | James W. Holm-Kennedy | Method and device for biochemical sensing |
| US5849486A (en) * | 1993-11-01 | 1998-12-15 | Nanogen, Inc. | Methods for hybridization analysis utilizing electrically controlled hybridization |
| EP0637382A1 (en) * | 1992-04-22 | 1995-02-08 | THE DOW CHEMICAL COMPANY (a Delaware corporation) | Polymeric film-based electrochemical sensor apparatus |
| US5919626A (en) * | 1997-06-06 | 1999-07-06 | Orchid Bio Computer, Inc. | Attachment of unmodified nucleic acids to silanized solid phase surfaces |
| US6232066B1 (en) * | 1997-12-19 | 2001-05-15 | Neogen, Inc. | High throughput assay system |
| ATE402407T1 (de) * | 1999-12-15 | 2008-08-15 | Univ Leland Stanford Junior | Kohlenstoff-nano-röhrchen-vorrichtung |
| US20040191260A1 (en) * | 2003-03-26 | 2004-09-30 | Technion Research & Development Foundation Ltd. | Compositions capable of specifically binding particular human antigen presenting molecule/pathogen-derived antigen complexes and uses thereof |
| EP1342075B1 (en) * | 2000-12-11 | 2008-09-10 | President And Fellows Of Harvard College | Device contaning nanosensors for detecting an analyte and its method of manufacture |
| CA2439188A1 (en) * | 2001-02-27 | 2002-09-19 | Institut Pasteur | Mhc-i-restricted presentation of hiv-1 virion antigens without viral replication. application to the stimulation of ctl and vaccination in vivo; analysis of vaccinating composition in vitro |
| EP1461606A4 (en) * | 2001-12-05 | 2005-06-29 | Univ Washington | MICROFLUIDIC DEVICE AND SURFACE DECORATION PROCESS FOR SOLID PHASE AFFINITY BINDING ASSAYS |
| JP2003322653A (ja) * | 2002-05-07 | 2003-11-14 | Toshiba Corp | プローブ固定支持体及びプローブ固定担体 |
| JP2006505806A (ja) * | 2002-11-08 | 2006-02-16 | ナノミックス・インコーポレーテッド | ナノチューブをベースとする生体分子の電子検知 |
| JP2004347532A (ja) * | 2003-05-23 | 2004-12-09 | Japan Science & Technology Agency | バイオセンサー |
| JP2008525822A (ja) * | 2004-12-28 | 2008-07-17 | ナノミックス・インコーポレーテッド | ポリヌクレオチド配列のdna検出/認識用ナノ電子装置 |
-
2005
- 2005-08-24 EP EP05810377A patent/EP1781771A2/en not_active Withdrawn
- 2005-08-24 WO PCT/US2005/030487 patent/WO2006024023A2/en not_active Ceased
- 2005-08-24 JP JP2007530178A patent/JP2008511008A/ja active Pending
-
2012
- 2012-08-07 JP JP2012175154A patent/JP5743974B2/ja not_active Expired - Fee Related
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