JP2008509084A5 - - Google Patents
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- Publication number
- JP2008509084A5 JP2008509084A5 JP2007513303A JP2007513303A JP2008509084A5 JP 2008509084 A5 JP2008509084 A5 JP 2008509084A5 JP 2007513303 A JP2007513303 A JP 2007513303A JP 2007513303 A JP2007513303 A JP 2007513303A JP 2008509084 A5 JP2008509084 A5 JP 2008509084A5
- Authority
- JP
- Japan
- Prior art keywords
- epitope
- activated
- polypeptide
- cells
- pro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001184 polypeptide Polymers 0.000 claims 27
- 102000004196 processed proteins & peptides Human genes 0.000 claims 27
- 108090000765 processed proteins & peptides Proteins 0.000 claims 27
- 210000001744 T-lymphocyte Anatomy 0.000 claims 23
- 150000001875 compounds Chemical class 0.000 claims 19
- 230000030833 cell death Effects 0.000 claims 17
- 150000001413 amino acids Chemical class 0.000 claims 14
- 238000000034 method Methods 0.000 claims 12
- 239000003937 drug carrier Substances 0.000 claims 9
- 239000008194 pharmaceutical composition Substances 0.000 claims 9
- 230000001939 inductive effect Effects 0.000 claims 6
- 239000003446 ligand Substances 0.000 claims 6
- 230000000694 effects Effects 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 210000004027 cell Anatomy 0.000 claims 1
- 230000034994 death Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57016104P | 2004-05-11 | 2004-05-11 | |
| US60/570,161 | 2004-05-11 | ||
| PCT/US2005/016441 WO2005110456A2 (en) | 2004-05-11 | 2005-05-11 | T-cell death-inducing epitopes |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012223627A Division JP2013049679A (ja) | 2004-05-11 | 2012-10-05 | T細胞死誘導エピトープ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008509084A JP2008509084A (ja) | 2008-03-27 |
| JP2008509084A5 true JP2008509084A5 (enExample) | 2008-06-26 |
| JP5710854B2 JP5710854B2 (ja) | 2015-04-30 |
Family
ID=35394670
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007513303A Expired - Fee Related JP5710854B2 (ja) | 2004-05-11 | 2005-05-11 | T細胞死誘導エピトープ |
| JP2012223627A Pending JP2013049679A (ja) | 2004-05-11 | 2012-10-05 | T細胞死誘導エピトープ |
| JP2015093320A Expired - Fee Related JP6109234B2 (ja) | 2004-05-11 | 2015-04-30 | T細胞死誘導エピトープ |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012223627A Pending JP2013049679A (ja) | 2004-05-11 | 2012-10-05 | T細胞死誘導エピトープ |
| JP2015093320A Expired - Fee Related JP6109234B2 (ja) | 2004-05-11 | 2015-04-30 | T細胞死誘導エピトープ |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US20060003940A1 (enExample) |
| EP (2) | EP1751300B1 (enExample) |
| JP (3) | JP5710854B2 (enExample) |
| KR (3) | KR20130018989A (enExample) |
| CN (3) | CN105777867A (enExample) |
| AR (1) | AR048840A1 (enExample) |
| AU (1) | AU2005244081B2 (enExample) |
| BR (1) | BRPI0510561A (enExample) |
| CA (1) | CA2565872C (enExample) |
| CL (1) | CL2008003587A1 (enExample) |
| EC (1) | ECSP067055A (enExample) |
| ES (1) | ES2655833T3 (enExample) |
| IL (1) | IL178837A (enExample) |
| MX (1) | MXPA06012987A (enExample) |
| NO (1) | NO20065648L (enExample) |
| NZ (3) | NZ578356A (enExample) |
| RU (1) | RU2412945C2 (enExample) |
| TW (3) | TWI454275B (enExample) |
| UA (3) | UA105492C2 (enExample) |
| WO (1) | WO2005110456A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7744888B2 (en) | 2001-08-03 | 2010-06-29 | Abgenomics Cooperatief U.A. | Methods of modulating T cell or natural killer cell activity with anti-P-selectin glycoprotein ligand 1 antibodies |
| US20040116333A1 (en) | 2001-08-03 | 2004-06-17 | Rong-Hwa Lin | Modulators of P-selectin glycoprotein ligand 1 |
| UY28886A1 (es) | 2004-05-10 | 2005-12-30 | Boehringer Ingelheim Int | Anticuerpos que consisten en polipéptidos y derivados conprendiendo tres secuencias conteniendo respectivamente los siguientes números de seq. id: 1-3 y 4-6; 7-9 y 10-12 y 13-15 ó 16-18 |
| BRPI0510561A (pt) * | 2004-05-11 | 2007-11-20 | Abgenomics Corp | epìtopos que induzem morte de célula t |
| WO2009093251A2 (en) * | 2008-01-24 | 2009-07-30 | Gavish-Galilee Bio Applications Ltd | Reovirus vaccine based on sigma c protein sequence |
| CN116063522A (zh) | 2011-06-13 | 2023-05-05 | 美国全心医药生技股份有限公司 | 抗psgl-1抗体及其用途 |
| ES2880731T3 (es) | 2016-01-08 | 2021-11-25 | Altrubio Inc | Anticuerpos anti-PSGL-1 tetravalentes y usos de los mismos |
| JP7244422B2 (ja) | 2017-01-11 | 2023-03-22 | ブリストル-マイヤーズ スクイブ カンパニー | Psgl-1アンタゴニスト及びその使用 |
| SG11201907848YA (en) | 2017-03-14 | 2019-09-27 | Five Prime Therapeutics Inc | Antibodies binding to vista at acidic ph |
| MX2020009786A (es) | 2018-03-21 | 2020-10-12 | Five Prime Therapeutics Inc | Anticuerpos de union a supresor de la activacion de celulas t que contiene el dominio variable de inmunoglobulina (vista) a ph acido. |
| US12091462B2 (en) | 2018-07-11 | 2024-09-17 | Five Prime Therapeutics, Inc. | Antibodies binding to vista at acidic pH |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| JPS61134325A (ja) * | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
| US5866363A (en) | 1985-08-28 | 1999-02-02 | Pieczenik; George | Method and means for sorting and identifying biological information |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US4704692A (en) | 1986-09-02 | 1987-11-03 | Ladner Robert C | Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5464778A (en) * | 1989-03-08 | 1995-11-07 | Board Of Regents Of The University Of Oklahoma | Glycoprotein ligand for P-selectin and methods of use thereof |
| US5378464A (en) * | 1989-03-08 | 1995-01-03 | Board Of Regents Of The University Of Oklahoma | Modulation of inflammatory responses by administration of GMP-140 or antibody to GMP-140 |
| US5690933A (en) * | 1989-05-31 | 1997-11-25 | Glaxo Wellcome Inc. | Monoclonal antibodies for inducing tolerance |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| KR100272077B1 (ko) | 1990-08-29 | 2000-11-15 | 젠팜인터내셔날,인코포레이티드 | 이종 항체를 생산할 수 있는 전이유전자를 가진 인간이외의 동물 |
| US5709859A (en) * | 1991-01-24 | 1998-01-20 | Bristol-Myers Squibb Company | Mixed specificity fusion proteins |
| US6124267A (en) * | 1991-02-05 | 2000-09-26 | Southpac Trust Internationals, Inc. | O-glycan inhibitors of selectin mediated inflammation derived from PSGL-1 |
| US6309639B1 (en) * | 1991-02-05 | 2001-10-30 | The Board Of Regents Of The University Of Oklahoma | Method for inhibiting an inflammatory response using antibodies to P-selectin glycoprotein ligand |
| US5972625A (en) * | 1991-05-06 | 1999-10-26 | The Regents Of The University Of California | Assays for inhibitors of leukocyte adhesion |
| US5843707A (en) * | 1992-10-23 | 1998-12-01 | Genetics Institute, Inc. | Nucleic acid encoding a novel P-selectin ligand protein |
| WO1994014836A1 (en) * | 1992-12-18 | 1994-07-07 | Centocor, Inc. | Peptide inhibitors of selectin binding |
| ES2126742T3 (es) * | 1993-01-25 | 1999-04-01 | Dana Farber Cancer Inst Inc | Selectinas quimericas obtenidas mediante intercambio de dominios - sus usos. |
| WO1995014787A1 (en) * | 1993-11-22 | 1995-06-01 | Centocor, Inc. | Peptide inhibitors of selecting binding |
| US6719972B1 (en) * | 1994-06-03 | 2004-04-13 | Repligen Corporation | Methods of inhibiting T cell proliferation or IL-2 accumulation with CTLA4- specific antibodies |
| ES2208759T3 (es) | 1995-08-03 | 2004-06-16 | Board Of Regents Of The University Of Oklahoma | O-glicanos inhibidores de la inflamacion mediada por selectina. |
| DE19629938C1 (de) | 1996-07-24 | 1997-11-27 | Gsf Forschungszentrum Umwelt | E-Cadherin-Mutationen als Grundlage zur Diagnostik und Therapie humaner maligner Tumoren |
| ATE252602T1 (de) * | 1996-08-27 | 2003-11-15 | Chiron Corp | Meningokokkus b-epitop ausbildende monoklonale antikoerper und deren verwendung zur herstellung von impfstoffzusammenstellungen |
| US5955259A (en) * | 1996-12-19 | 1999-09-21 | Brandeis University | Method for assessing modulation of potassium ion channel activity |
| DE69837529T2 (de) * | 1997-02-12 | 2007-07-26 | Electrophoretics Ltd., Cobham | Proteinmarker für lungenkrebs und deren verwendung |
| US6551994B1 (en) | 1997-04-10 | 2003-04-22 | Mcgill University | Compounds and methods for inhibiting the interaction between α-catenin and β-catenin |
| PT1032674E (pt) | 1997-11-21 | 2007-03-30 | Serono Genetics Inst Sa | Sequência genómica e polipéptidos (de chlamydia pneumoniae), seus fragmentos e suas utilizações, em particular para o diagnóstico, prevenção e tratamento de infacção |
| WO1999043353A2 (en) * | 1998-02-26 | 1999-09-02 | Boehringer Ingelheim Pharmaceuticals, Inc. | Combination anti-selectin and immunosuppressant therapy |
| NZ528610A (en) | 1998-10-30 | 2005-03-24 | Inst Genetics Llc | Inhibition of differentiation of cytotoxic T-cells by P-selectin ligand (PSGL) antagonists |
| DE19925199A1 (de) * | 1999-06-01 | 2000-12-07 | Medigene Ag | Zytotoxische T-Zellepitope des Papillomavirus L1-Proteins und ihre Verwendung in Diagnostik und Therapie |
| AU2001251612A1 (en) * | 2000-04-14 | 2001-10-30 | Millennium Pharmaceuticals, Inc. | Roles of jak/stat family members in tolerance induction |
| AU2000274809A1 (en) * | 2000-09-12 | 2002-03-26 | Genetics Institute Llc | Inhibition of stenosis or restenosis by p-selectin antagonists |
| US20040002450A1 (en) * | 2000-12-29 | 2004-01-01 | Janette Lazarovits | Y17 - isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof |
| JP2005503756A (ja) * | 2000-12-29 | 2005-02-10 | サビエント ファーマシューティカルズ,インコーポレイティド | 硫酸化部分を含むエピトープを含む単離分子、当該エピトープに対する抗体、及びその使用 |
| US20040001839A1 (en) * | 2000-12-29 | 2004-01-01 | Avigdor Levanon | Multimers - isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof |
| NZ512341A (en) * | 2001-06-13 | 2004-02-27 | Bayer Ag | Polynucleotides between 15 and 100 base pairs in length coding for parapoxvirus ovis (PPVO)/vaccinia virus recombinant (VVOV) viral genome fragments |
| US20040116333A1 (en) | 2001-08-03 | 2004-06-17 | Rong-Hwa Lin | Modulators of P-selectin glycoprotein ligand 1 |
| US7744888B2 (en) | 2001-08-03 | 2010-06-29 | Abgenomics Cooperatief U.A. | Methods of modulating T cell or natural killer cell activity with anti-P-selectin glycoprotein ligand 1 antibodies |
| WO2003032925A2 (en) * | 2001-10-19 | 2003-04-24 | Cummings Richard D | Glycosulfopeptide inhibitors and methods of use thereof |
| RU2005101621A (ru) * | 2002-07-01 | 2005-11-20 | Савиент Фармасьютикалс, Инк. (Us) | Антитела и их применения |
| AU2003297573A1 (en) * | 2002-11-27 | 2004-06-23 | Cedric Francois | Compositions and methods for treating transplants |
| US20050152906A1 (en) * | 2003-06-30 | 2005-07-14 | Avigdor Levanon | Specific human antibodies |
| AU2004273807B2 (en) * | 2003-09-15 | 2011-06-09 | Abgenomics Cooperatief U.A. | Modulators of P-Selectin Glycoprotein Ligand 1 |
| UY28886A1 (es) | 2004-05-10 | 2005-12-30 | Boehringer Ingelheim Int | Anticuerpos que consisten en polipéptidos y derivados conprendiendo tres secuencias conteniendo respectivamente los siguientes números de seq. id: 1-3 y 4-6; 7-9 y 10-12 y 13-15 ó 16-18 |
| BRPI0510561A (pt) | 2004-05-11 | 2007-11-20 | Abgenomics Corp | epìtopos que induzem morte de célula t |
| CN116063522A (zh) | 2011-06-13 | 2023-05-05 | 美国全心医药生技股份有限公司 | 抗psgl-1抗体及其用途 |
-
2005
- 2005-05-11 BR BRPI0510561-7A patent/BRPI0510561A/pt not_active Application Discontinuation
- 2005-05-11 US US11/127,804 patent/US20060003940A1/en not_active Abandoned
- 2005-05-11 KR KR1020137000714A patent/KR20130018989A/ko not_active Ceased
- 2005-05-11 ES ES05747869.5T patent/ES2655833T3/es not_active Expired - Lifetime
- 2005-05-11 CN CN201610245201.7A patent/CN105777867A/zh active Pending
- 2005-05-11 NZ NZ578356A patent/NZ578356A/en not_active IP Right Cessation
- 2005-05-11 KR KR1020127015966A patent/KR20120085921A/ko not_active Ceased
- 2005-05-11 UA UAA201100442A patent/UA105492C2/uk unknown
- 2005-05-11 EP EP05747869.5A patent/EP1751300B1/en not_active Expired - Lifetime
- 2005-05-11 TW TW100124987A patent/TWI454275B/zh not_active IP Right Cessation
- 2005-05-11 CA CA2565872A patent/CA2565872C/en not_active Expired - Fee Related
- 2005-05-11 TW TW094115275A patent/TWI446920B/zh not_active IP Right Cessation
- 2005-05-11 KR KR1020067024895A patent/KR101278077B1/ko not_active Expired - Fee Related
- 2005-05-11 NZ NZ551625A patent/NZ551625A/en not_active IP Right Cessation
- 2005-05-11 AU AU2005244081A patent/AU2005244081B2/en not_active Ceased
- 2005-05-11 JP JP2007513303A patent/JP5710854B2/ja not_active Expired - Fee Related
- 2005-05-11 RU RU2006143689/10A patent/RU2412945C2/ru not_active IP Right Cessation
- 2005-05-11 MX MXPA06012987A patent/MXPA06012987A/es active IP Right Grant
- 2005-05-11 CN CN201210079297.6A patent/CN102617708B/zh not_active Expired - Fee Related
- 2005-05-11 AR ARP050101904A patent/AR048840A1/es not_active Application Discontinuation
- 2005-05-11 UA UAA201100443A patent/UA105493C2/uk unknown
- 2005-05-11 NZ NZ590478A patent/NZ590478A/en not_active IP Right Cessation
- 2005-05-11 EP EP11187348A patent/EP2450365A1/en not_active Withdrawn
- 2005-05-11 TW TW100124986A patent/TWI454274B/zh not_active IP Right Cessation
- 2005-05-11 WO PCT/US2005/016441 patent/WO2005110456A2/en not_active Ceased
- 2005-05-11 CN CN2005800234022A patent/CN1985000B/zh not_active Expired - Fee Related
- 2005-11-05 UA UAA200613088A patent/UA94382C2/uk unknown
-
2006
- 2006-10-24 IL IL178837A patent/IL178837A/en not_active IP Right Cessation
- 2006-12-07 NO NO20065648A patent/NO20065648L/no not_active Application Discontinuation
- 2006-12-08 EC EC2006007055A patent/ECSP067055A/es unknown
-
2008
- 2008-12-01 CL CL2008003587A patent/CL2008003587A1/es unknown
-
2010
- 2010-07-28 US US12/845,036 patent/US9494574B2/en not_active Expired - Fee Related
-
2012
- 2012-10-05 JP JP2012223627A patent/JP2013049679A/ja active Pending
-
2013
- 2013-08-29 US US14/013,484 patent/US20140065176A1/en not_active Abandoned
-
2015
- 2015-04-30 JP JP2015093320A patent/JP6109234B2/ja not_active Expired - Fee Related
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