CA2565872C - T-cell death-inducing epitopes - Google Patents

T-cell death-inducing epitopes Download PDF

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Publication number
CA2565872C
CA2565872C CA2565872A CA2565872A CA2565872C CA 2565872 C CA2565872 C CA 2565872C CA 2565872 A CA2565872 A CA 2565872A CA 2565872 A CA2565872 A CA 2565872A CA 2565872 C CA2565872 C CA 2565872C
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Canada
Prior art keywords
polypeptide
cells
compound
epitope
activated
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Expired - Fee Related
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CA2565872A
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English (en)
French (fr)
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CA2565872A1 (en
Inventor
Ronghwa Lin
Chunqnan Chang
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Abgenomics Cooperatief UA
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Abgenomics Cooperatief UA
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
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    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1761—Apoptosis related proteins, e.g. Apoptotic protease-activating factor-1 (APAF-1), Bax, Bax-inhibitory protein(s)(BI; bax-I), Myeloid cell leukemia associated protein (MCL-1), Inhibitor of apoptosis [IAP] or Bcl-2
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    • C—CHEMISTRY; METALLURGY
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    • C07K14/4747—Apoptosis related proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1021—Tetrapeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
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    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
    • C—CHEMISTRY; METALLURGY
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    • G—PHYSICS
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CA2565872A 2004-05-11 2005-05-11 T-cell death-inducing epitopes Expired - Fee Related CA2565872C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57016104P 2004-05-11 2004-05-11
US60/570,161 2004-05-11
PCT/US2005/016441 WO2005110456A2 (en) 2004-05-11 2005-05-11 T-cell death-inducing epitopes

Publications (2)

Publication Number Publication Date
CA2565872A1 CA2565872A1 (en) 2005-11-24
CA2565872C true CA2565872C (en) 2016-06-21

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CA2565872A Expired - Fee Related CA2565872C (en) 2004-05-11 2005-05-11 T-cell death-inducing epitopes

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US (3) US20060003940A1 (enExample)
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TWI446920B (zh) 2014-08-01
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IL178837A0 (en) 2007-03-08
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