JP2008508188A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2008508188A5 JP2008508188A5 JP2007504792A JP2007504792A JP2008508188A5 JP 2008508188 A5 JP2008508188 A5 JP 2008508188A5 JP 2007504792 A JP2007504792 A JP 2007504792A JP 2007504792 A JP2007504792 A JP 2007504792A JP 2008508188 A5 JP2008508188 A5 JP 2008508188A5
- Authority
- JP
- Japan
- Prior art keywords
- thiazol
- ethyl
- phenyl
- amino
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CCN(*)C(c1ccccc1)=O Chemical compound CCN(*)C(c1ccccc1)=O 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2004904196 | 2004-07-27 | ||
| AU2004904196A AU2004904196A0 (en) | 2004-07-27 | Thiazole Derivatives Having VAP-1 Inhibitory Activity | |
| PCT/JP2005/014136 WO2006011631A2 (en) | 2004-07-27 | 2005-07-27 | Thiazole derivatives having vap-1 inhibitory activity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008508188A JP2008508188A (ja) | 2008-03-21 |
| JP2008508188A5 true JP2008508188A5 (enExample) | 2008-08-14 |
| JP4978464B2 JP4978464B2 (ja) | 2012-07-18 |
Family
ID=35734947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007504792A Expired - Fee Related JP4978464B2 (ja) | 2004-07-27 | 2005-07-27 | Ｖａｐ−１阻害剤活性を有するチアゾール誘導体 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20070254931A1 (enExample) |
| EP (1) | EP1786792B1 (enExample) |
| JP (1) | JP4978464B2 (enExample) |
| KR (1) | KR20070050932A (enExample) |
| CN (1) | CN101031555A (enExample) |
| AT (1) | ATE427941T1 (enExample) |
| CA (1) | CA2575411A1 (enExample) |
| DE (1) | DE602005013793D1 (enExample) |
| ES (1) | ES2324922T3 (enExample) |
| WO (1) | WO2006011631A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103554095A (zh) | 2006-02-15 | 2014-02-05 | Abbvie公司 | 新的乙酰辅酶a羧化酶(acc)抑制剂及其在糖尿病、肥胖症和代谢综合征中的应用 |
| CN101384568B (zh) * | 2006-02-15 | 2012-12-12 | 雅培制药有限公司 | 乙酰辅酶a羧化酶(acc)抑制剂及其在糖尿病、肥胖症和代谢综合征中的应用 |
| US20100190834A1 (en) * | 2007-06-25 | 2010-07-29 | R-Tech Ueno, Ltd. | Composition for ophtalmic disease associated with hypoxia or ischemia |
| KR20100096094A (ko) | 2007-10-19 | 2010-09-01 | 가부시키가이샤 아루떼꾸 우에노 | 백내장 처치를 위한 의약 조성물 |
| US20090170770A1 (en) * | 2007-11-06 | 2009-07-02 | Ali Hafezi-Moghadam | Methods and compositions for treating conditions associated with angiogenesis using a vascular adhesion protein-1 (vap 1) inhibitor |
| BRPI0906925A2 (pt) * | 2008-01-18 | 2019-09-24 | Allergan Inc | agentes adrenérgicos do subtipo alfa 2 seletivos e métodos de uso dos mesmos |
| TWI437986B (zh) | 2008-01-31 | 2014-05-21 | R Tech Ueno Ltd | 噻唑衍生物及使用該衍生物作為ｖａｐ－１抑制劑之用途 |
| TWI490214B (zh) | 2008-05-30 | 2015-07-01 | 艾德克 上野股份有限公司 | 苯或噻吩衍生物及該等作為ｖａｐ－１抑制劑之用途 |
| JP2012506386A (ja) * | 2008-10-21 | 2012-03-15 | メタボレックス， インコーポレイテッド | アリールｇｐｒ１２０受容体アゴニストおよびその使用 |
| UA112154C2 (uk) | 2009-09-08 | 2016-08-10 | Біоті Терапіс Корп. | Застосування повністю людського анти-vap-1-антитіла для лікування фіброзних станів |
| FI20115234A0 (fi) | 2011-03-08 | 2011-03-08 | Biotie Therapies Corp | Uusia pyridatsinoni- ja pyridoniyhdisteitä |
| EA024102B1 (ru) | 2011-03-15 | 2016-08-31 | Астеллас Фарма Инк. | Гуанидиновые соединения, полезные для предотвращения и/или лечения диабетической нефропатии или диабетического отека желтого пятна |
| JP6050238B2 (ja) | 2011-10-19 | 2016-12-21 | 興和株式会社 | 新規なスピロインドリン化合物、及びそれを含有する医薬 |
| US20160113893A1 (en) | 2013-06-12 | 2016-04-28 | Proximagen Limited | New therapeutic uses of enzyme inhibitors |
| ES2714125T3 (es) | 2014-04-15 | 2019-05-27 | Pecsi Tudomanyegyetem | Inhibidores de la amino oxidasa sensible a la semicarbazida para uso como analgésicos en una neuropatía traumática y una inflamación neurogénica |
| WO2015189534A1 (en) | 2014-06-12 | 2015-12-17 | Proximagen Limited | Vap-1 inhibitors for treating muscular dystrophy |
| CN104478828B (zh) * | 2014-12-10 | 2016-07-06 | 漳州片仔癀药业股份有限公司 | 2-氨基-7-取代苯并噻唑类化合物及其制备方法与用途 |
| JO3546B1 (ar) | 2015-01-09 | 2020-07-05 | Kyowa Kirin Co Ltd | طريقة لإنتاج مشتق ثيازول |
| JP2018076236A (ja) | 2015-06-05 | 2018-05-17 | 株式会社アールテック・ウエノ | がんを処置するための医薬組成物 |
| MX383577B (es) * | 2015-08-06 | 2025-03-14 | Ube Industries | Derivados sustituidos de guanidina. |
| CA3007768A1 (en) | 2015-12-07 | 2017-06-15 | Benevolentai Cambridge Limited | Vap-1 inhibitors for treating pain |
| EP3455216B1 (en) * | 2016-05-12 | 2020-11-04 | Boehringer Ingelheim International GmbH | Pyridinyl derivatives, pharmaceutical compositions and uses thereof as aoc3 inhibitors |
| MX2019007786A (es) * | 2016-12-28 | 2019-08-16 | Ube Industries | Compuestos sustituidos de guanidina. |
| US10213306B2 (en) | 2017-03-31 | 2019-02-26 | Neochord, Inc. | Minimally invasive heart valve repair in a beating heart |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4511574A (en) * | 1981-01-08 | 1985-04-16 | Mitsui Toatsu Kagaku Kabushiki Kaisha | N-(4-Phenyl-2-thiazolyl)carbamate derivatives |
| US4699928A (en) * | 1984-07-13 | 1987-10-13 | Merrell Dow Pharmaceuticals Inc. | Fluoroallylamine derivatives |
| IT1181871B (it) * | 1985-04-01 | 1987-09-30 | Consiglio Nazionale Ricerche | Inibitori selettivi delle benzilamminossidasi rispetto ad altre amminossidasi |
| US4650907A (en) * | 1985-12-05 | 1987-03-17 | Merrell Dow Pharmaceuticals Inc. | Nonaromatic fluoroallylamine MAO inhibitors |
| US4916151A (en) * | 1985-12-05 | 1990-04-10 | Merrell Dow Pharmaceuticals Inc. | Method of treating parkinson's syndrome |
| US4965288A (en) * | 1988-02-25 | 1990-10-23 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of lysyl oxidase |
| US4943593A (en) * | 1988-02-25 | 1990-07-24 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of lysyl oxidase |
| US5021456A (en) * | 1988-02-25 | 1991-06-04 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of lysyl oxidase |
| US5059814A (en) * | 1988-11-30 | 1991-10-22 | The California Institute Of Technology | Winner-take-all circuits for neural computing systems |
| JPH0848664A (ja) * | 1994-08-05 | 1996-02-20 | Hisamitsu Pharmaceut Co Inc | 新規なグアニジノ安息香酸エステル誘導体 |
| GB9506188D0 (en) * | 1995-03-27 | 1995-05-17 | Fujisawa Pharmaceutical Co | Amidine derivatives |
| IL153767A0 (en) * | 2000-07-05 | 2003-07-06 | Biotie Therapies Corp | Inhibitors of copper-containing amine oxidases |
| AU2002214505A1 (en) * | 2000-11-09 | 2002-05-21 | Biovitrum Ab | New use of 4, 5, 6, 7-tetrahydroimidazo-(4,5-c)pyridine derivatives |
| CA2514573A1 (en) * | 2003-01-27 | 2004-08-12 | Astellas Pharma Inc. | Thiazole derivatives and their use as vap-1 inhibitors |
| KR20120045062A (ko) * | 2003-03-31 | 2012-05-08 | 가부시키가이샤 아루떼꾸 우에노 | 혈관 과투과 질환의 치료방법 |
| US20070208068A1 (en) * | 2004-03-18 | 2007-09-06 | R-Tech Ueno, Ltd. & Astellas Pharma Inc. | Aqueous Composition Comprising Thiazole Derivative |
-
2005
- 2005-07-27 JP JP2007504792A patent/JP4978464B2/ja not_active Expired - Fee Related
- 2005-07-27 CN CNA200580031703XA patent/CN101031555A/zh active Pending
- 2005-07-27 AT AT05768525T patent/ATE427941T1/de not_active IP Right Cessation
- 2005-07-27 KR KR1020077004487A patent/KR20070050932A/ko not_active Ceased
- 2005-07-27 ES ES05768525T patent/ES2324922T3/es not_active Expired - Lifetime
- 2005-07-27 EP EP05768525A patent/EP1786792B1/en not_active Expired - Lifetime
- 2005-07-27 WO PCT/JP2005/014136 patent/WO2006011631A2/en not_active Ceased
- 2005-07-27 CA CA002575411A patent/CA2575411A1/en not_active Abandoned
- 2005-07-27 US US11/572,772 patent/US20070254931A1/en not_active Abandoned
- 2005-07-27 DE DE602005013793T patent/DE602005013793D1/de not_active Expired - Lifetime
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4978464B2 (ja) | Ｖａｐ−１阻害剤活性を有するチアゾール誘導体 | |
| JP4650412B2 (ja) | チアゾール誘導体およびｖａｐ−１阻害剤としてのその使用 | |
| AU2009209885B2 (en) | Thiazole derivative and use thereof as VAP-1 inhibitor | |
| JP4758337B2 (ja) | 血管透過性亢進疾患を治療する方法 | |
| US20080015202A1 (en) | Thiazole Derivatives Having Vap-1 Inhibitory Activity | |
| JP2008512346A5 (enExample) | ||
| CN1209352C (zh) | 肼衍生物 | |
| US20110269953A1 (en) | Nitrogen and Sulfur-Containing Heterocycle Derivatives |