JP2008506362A5 - - Google Patents
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- Publication number
- JP2008506362A5 JP2008506362A5 JP2007511013A JP2007511013A JP2008506362A5 JP 2008506362 A5 JP2008506362 A5 JP 2008506362A5 JP 2007511013 A JP2007511013 A JP 2007511013A JP 2007511013 A JP2007511013 A JP 2007511013A JP 2008506362 A5 JP2008506362 A5 JP 2008506362A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nicotiana
- tobacco
- nucleic acid
- plant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000007523 nucleic acids Chemical class 0.000 claims description 390
- 108091028043 Nucleic acid sequence Proteins 0.000 claims description 317
- 235000002637 Nicotiana tabacum Nutrition 0.000 claims description 138
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 97
- 238000000034 method Methods 0.000 claims description 70
- 241000196324 Embryophyta Species 0.000 claims description 68
- 108020004707 nucleic acids Proteins 0.000 claims description 32
- 102000039446 nucleic acids Human genes 0.000 claims description 32
- 230000014509 gene expression Effects 0.000 claims description 25
- 241000208125 Nicotiana Species 0.000 claims description 19
- 229920001184 polypeptide Polymers 0.000 claims description 17
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 17
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 17
- 230000001939 inductive effect Effects 0.000 claims description 16
- 108090000623 proteins and genes Proteins 0.000 claims description 11
- 108090000790 Enzymes Proteins 0.000 claims description 7
- 102000004190 Enzymes Human genes 0.000 claims description 7
- 108700019146 Transgenes Proteins 0.000 claims description 7
- 230000000694 effects Effects 0.000 claims description 7
- 230000000692 anti-sense effect Effects 0.000 claims description 6
- 239000012634 fragment Substances 0.000 claims description 6
- 150000001413 amino acids Chemical class 0.000 claims description 4
- 230000000295 complement effect Effects 0.000 claims description 2
- 244000061176 Nicotiana tabacum Species 0.000 claims 137
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 claims 18
- 101000615488 Homo sapiens Methyl-CpG-binding domain protein 2 Proteins 0.000 claims 18
- 210000004027 cell Anatomy 0.000 claims 18
- 229960002715 nicotine Drugs 0.000 claims 18
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 claims 18
- 235000019505 tobacco product Nutrition 0.000 claims 18
- 239000003550 marker Substances 0.000 claims 15
- 238000009395 breeding Methods 0.000 claims 13
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 claims 12
- 239000005977 Ethylene Substances 0.000 claims 12
- 102100021299 Methyl-CpG-binding domain protein 2 Human genes 0.000 claims 12
- 230000009758 senescence Effects 0.000 claims 10
- 230000035772 mutation Effects 0.000 claims 9
- 230000001488 breeding effect Effects 0.000 claims 8
- 238000004519 manufacturing process Methods 0.000 claims 8
- 230000002068 genetic effect Effects 0.000 claims 6
- 241000250377 Nicotiana amplexicaulis Species 0.000 claims 5
- 241000207746 Nicotiana benthamiana Species 0.000 claims 5
- 241000208113 Nicotiana debneyi Species 0.000 claims 5
- 241000862464 Nicotiana excelsior Species 0.000 claims 5
- 241001495644 Nicotiana glutinosa Species 0.000 claims 5
- 241000493375 Nicotiana quadrivalvis Species 0.000 claims 5
- 241001290303 Nicotiana repanda Species 0.000 claims 5
- 241001144480 Nicotiana suaveolens Species 0.000 claims 5
- 108020004414 DNA Proteins 0.000 claims 4
- 241001144497 Nicotiana africana Species 0.000 claims 4
- 241001144490 Nicotiana arentsii Species 0.000 claims 4
- 241001144496 Nicotiana corymbosa Species 0.000 claims 4
- 241000250379 Nicotiana exigua Species 0.000 claims 4
- 241000250030 Nicotiana miersii Species 0.000 claims 4
- 241001144476 Nicotiana nesophila Species 0.000 claims 4
- 241000250041 Nicotiana noctiflora Species 0.000 claims 4
- 241000228665 Nicotiana nudicaulis Species 0.000 claims 4
- 241001144493 Nicotiana obtusifolia Species 0.000 claims 4
- 241000208132 Nicotiana otophora Species 0.000 claims 4
- 241000228667 Nicotiana palmeri Species 0.000 claims 4
- 241000876839 Nicotiana paniculata Species 0.000 claims 4
- 241000250042 Nicotiana petunioides Species 0.000 claims 4
- 241000208133 Nicotiana plumbaginifolia Species 0.000 claims 4
- 238000003976 plant breeding Methods 0.000 claims 4
- 241001144503 Nicotiana goodspeedii Species 0.000 claims 3
- 241000250366 Nicotiana gossei Species 0.000 claims 3
- 241001144499 Nicotiana maritima Species 0.000 claims 3
- 230000001055 chewing effect Effects 0.000 claims 3
- 235000019506 cigar Nutrition 0.000 claims 3
- 235000019504 cigarettes Nutrition 0.000 claims 3
- 230000001965 increasing effect Effects 0.000 claims 3
- 230000013011 mating Effects 0.000 claims 3
- 208000035240 Disease Resistance Diseases 0.000 claims 2
- 206010020649 Hyperkeratosis Diseases 0.000 claims 2
- 108091092878 Microsatellite Proteins 0.000 claims 2
- 241000250031 Nicotiana megalosiphon Species 0.000 claims 2
- 241001144500 Nicotiana rosulata Species 0.000 claims 2
- 230000003321 amplification Effects 0.000 claims 2
- 230000003247 decreasing effect Effects 0.000 claims 2
- 230000037430 deletion Effects 0.000 claims 2
- 238000012217 deletion Methods 0.000 claims 2
- 210000002257 embryonic structure Anatomy 0.000 claims 2
- 238000003306 harvesting Methods 0.000 claims 2
- 230000037431 insertion Effects 0.000 claims 2
- 238000003780 insertion Methods 0.000 claims 2
- 230000003902 lesion Effects 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- 230000000877 morphologic effect Effects 0.000 claims 2
- 238000003199 nucleic acid amplification method Methods 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 230000010152 pollination Effects 0.000 claims 2
- 230000001323 posttranslational effect Effects 0.000 claims 2
- 210000001938 protoplast Anatomy 0.000 claims 2
- 238000007894 restriction fragment length polymorphism technique Methods 0.000 claims 2
- 230000010153 self-pollination Effects 0.000 claims 2
- 238000006467 substitution reaction Methods 0.000 claims 2
- 230000008685 targeting Effects 0.000 claims 2
- 230000002103 transcriptional effect Effects 0.000 claims 2
- 230000009261 transgenic effect Effects 0.000 claims 2
- 230000005945 translocation Effects 0.000 claims 2
- 241000250368 Nicotiana knightiana Species 0.000 claims 1
- 241001144504 Nicotiana occidentalis subsp. hesperis Species 0.000 claims 1
- 241000208134 Nicotiana rustica Species 0.000 claims 1
- 230000032683 aging Effects 0.000 claims 1
- 230000002950 deficient Effects 0.000 claims 1
- 230000007613 environmental effect Effects 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 244000052769 pathogen Species 0.000 claims 1
- 230000001717 pathogenic effect Effects 0.000 claims 1
- 230000001172 regenerating effect Effects 0.000 claims 1
- 238000002864 sequence alignment Methods 0.000 description 22
- 108010029162 tobacco nicotine demethylase Proteins 0.000 description 13
- 238000012228 RNA interference-mediated gene silencing Methods 0.000 description 9
- 230000009368 gene silencing by RNA Effects 0.000 description 9
- 108091032973 (ribonucleotides)n+m Proteins 0.000 description 8
- 108091026890 Coding region Proteins 0.000 description 3
- 102000040650 (ribonucleotides)n+m Human genes 0.000 description 2
- 238000002493 microarray Methods 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
Applications Claiming Priority (19)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56623504P | 2004-04-29 | 2004-04-29 | |
| US60/566,235 | 2004-04-29 | ||
| US60735704P | 2004-09-03 | 2004-09-03 | |
| US10/934,944 US7812227B2 (en) | 2001-11-13 | 2004-09-03 | Cloning of cytochrome p450 genes from nicotiana |
| US60/607,357 | 2004-09-03 | ||
| US10/934,944 | 2004-09-03 | ||
| US10/943,507 US7855318B2 (en) | 2001-11-13 | 2004-09-17 | Cloning of cytochrome P450 genes from Nicotiana |
| US10/943,507 | 2004-09-17 | ||
| USPCT/US/2004/34065 | 2004-10-15 | ||
| PCT/US2004/034218 WO2005038018A2 (en) | 2003-10-16 | 2004-10-15 | Cloning of cytochrome p450 genes from nicotiana |
| USPCT/US/2004/34218 | 2004-10-15 | ||
| PCT/US2004/034065 WO2005038033A2 (en) | 2003-10-16 | 2004-10-15 | Cloning of cytochrome p450 genes from nicotiana |
| US64676405P | 2005-01-25 | 2005-01-25 | |
| US60/646,764 | 2005-01-25 | ||
| US66509705P | 2005-03-24 | 2005-03-24 | |
| US66545105P | 2005-03-24 | 2005-03-24 | |
| US60/665,451 | 2005-03-24 | ||
| US60/665,097 | 2005-03-24 | ||
| PCT/US2005/014803 WO2005111217A2 (en) | 2004-04-29 | 2005-04-27 | Nicotiana nucleic acid molecules and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011062976A Division JP5289491B2 (ja) | 2004-04-29 | 2011-03-22 | Ｎｉｃｏｔｉａｎａ核酸分子およびその用途 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008506362A JP2008506362A (ja) | 2008-03-06 |
| JP2008506362A5 true JP2008506362A5 (enExample) | 2008-09-18 |
| JP4753937B2 JP4753937B2 (ja) | 2011-08-24 |
Family
ID=44597264
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007511013A Expired - Fee Related JP4753937B2 (ja) | 2004-04-29 | 2005-04-27 | Ｎｉｃｏｔｉａｎａ核酸分子およびその用途 |
| JP2011062976A Expired - Fee Related JP5289491B2 (ja) | 2004-04-29 | 2011-03-22 | Ｎｉｃｏｔｉａｎａ核酸分子およびその用途 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011062976A Expired - Fee Related JP5289491B2 (ja) | 2004-04-29 | 2011-03-22 | Ｎｉｃｏｔｉａｎａ核酸分子およびその用途 |
Country Status (1)
| Country | Link |
|---|---|
| JP (2) | JP4753937B2 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105586346B (zh) * | 2015-12-01 | 2019-07-02 | 贵州省烟草科学研究院 | 一种烟草基因NtTCTP及其用途 |
| EP4483710A1 (en) | 2022-02-24 | 2025-01-01 | Japan Tobacco Inc. | Low-reversion type tobacco plant having low nornicotine content, method for selecting same, and method for producing tobacco plant line |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7700851B2 (en) * | 2001-11-13 | 2010-04-20 | U.S. Smokeless Tobacco Company | Tobacco nicotine demethylase genomic clone and uses thereof |
| AU2003220165A1 (en) * | 2002-03-12 | 2003-09-29 | U.S. Smokeless Tobacco Company | Cloning of cytochrome p450 genes from nicotiana |
| WO2004035745A2 (en) * | 2002-10-16 | 2004-04-29 | U.S. Smokeless Tobacco Company | Cloning of cytochrome p450 genes from nicotiana |
-
2005
- 2005-04-27 JP JP2007511013A patent/JP4753937B2/ja not_active Expired - Fee Related
-
2011
- 2011-03-22 JP JP2011062976A patent/JP5289491B2/ja not_active Expired - Fee Related
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