JP2008273908A - Composition for oral cavity - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a composition for oral cavity at a low cost having no problem in the feeling in use such as flavor and taste and enhanced in sensation of coolness of menthol. <P>SOLUTION: This composition for oral cavity contains components (A) and (B), and the weight ratio of component (B) to component (A), (B)/(A), is 1/0.001-1/0.1 wherein component (A) is at least one selected from the group consisting of α-phellandrene, aromadendrene, sabinene, 3-carene, terpinene, elemene, ocimene, and nerolidol, and component (B) is menthol. <P>COPYRIGHT: (C)2009,JPO&INPIT

Description

  The present invention relates to an oral composition such as a toothpaste, a mouthwash, and a mouth freshener.

  Mouthol, which is the main ingredient of peppermint oil and peppermint oil, is added to oral compositions such as toothpaste, mouthwash, chewing gum, and refreshing confectionery in the mouth to make the mouth feel refreshed during and after use. . In order to give and maintain a higher refreshing feeling, it is effective to increase the amount of menthol. However, when menthol is highly blended, there is a problem that a bitter taste derived from menthol appears and the feeling of use deteriorates. .

  Therefore, various methods for enhancing the refreshing feeling of menthol have been devised. For example, menthol includes dioxolane-2-acetic acid derivatives (Patent Document 1), ketones, alcohols, tetrahydrofuran derivatives and the like (Patent Document 2), S compounds (Patent Document 3), tea tree (Patent Document 4), p- A method for enhancing the refreshing feeling of menthol by using a menthane derivative (Patent Document 5), a quinic acid derivative (Patent Document 6), etc., and a cooling sensation agent and a fragrance composition using the method have been proposed. Yes.

  However, with the techniques described in Patent Documents 1 to 4, it is difficult to obtain an oral composition having a good feeling of use due to the strong flavor of the refreshing feeling enhancing material itself. Moreover, the raw material used by patent documents 5-6 is expensive, and it is difficult to mix | blend abundantly with oral compositions, such as toothpaste.

Japanese Patent Laid-Open No. 7-228887 Japanese Patent Laid-Open No. 8-157862 JP 9-104891 A JP-A-9-263786 JP 2004-59474 A JP 2006-104229 A

  Therefore, an object of the present invention is to provide an oral composition having no problem in feeling of use such as flavor and enhanced menthol refreshment at low cost.

  The present inventors have found that the above-mentioned problems can be solved by using a specific terpene together with menthol in a certain ratio.

The present invention includes components (A) and (B), and a weight ratio (B) :( A) between component (B) and component (A) is from 1: 0.001 to 1: 0.1. Is to provide.
(A) one or more terpenes selected from α-ferrandolene, aromadendrene, sabinene, 3-carene, tarpinene, elemen, ocimene and nerolidol
(B) Menthol

  The composition for oral cavity of the present invention has no problem in use feeling such as flavor, enhances the refreshing feeling of menthol, and is inexpensive.

  As the component (A), terpenes selected from α-ferrandrene, aromadendrene, sabinene, 3-carene, tarpinene, elemen, ocimene and nerolidol are used alone or in combination of two or more. be able to. Moreover, although these terpenes itself may be used, you may use the plant essential oil containing 1 or more of these compounds. These essential oils may be used as they are, but those having a strong odor may be further fractionated by redistillation, silica gel column, liquid-liquid extraction or the like.

  Examples of plant essential oils rich in α-ferrandrene include African nutmeg, dill, sinus, fennel, and warmwood. Examples of plant essential oils that contain a large amount of aromadendren include tamarind and tage. Examples of plant essential oils that contain a large amount of sabinene include sabin juniper, lisea cubeba, grapefruit leaf, orange leaf, cedar leaf, and nutmeg. Examples of plant essential oils rich in 3-carene include mango, false acacia and black pepper. Examples of plant essential oils that contain a large amount of tarpinene include Italian citron, tea tree, and grapefruit leaf. Examples of plant essential oils that contain a large amount of elements include African blue basil, gypsophila, and daisy. Examples of plant essential oils that contain a large amount of ocimen include cinnamon, magnolia, and symbidium. Examples of plant essential oils containing a large amount of nerolidol include magnolia, pomelo, lemon flower, plumeria and the like.

  Weight ratio of component (B) menthol to component (A) (B): (A) suppresses oily odor, which is characteristic of component (A), and sufficiently improves the effect of component (A) From the viewpoint of exhibiting, it is set to 1: 0.001 to 1: 0.1. In order to prepare various types of fragrances as a composition for the oral cavity, the amount of 1: 0.001 to 1: 0.05, which is an amount in which the oiliness peculiar to the component (A) is less felt, is more preferable.

  When using a plant essential oil that contains a large amount of component (A) or a fractionated essential oil, the content of component (A) is calculated using an instrument such as gas chromatography. (B) The weight ratio with menthol can be determined.

  The menthol content of component (B) may be the amount normally used in oral compositions, but the refreshing effect of component (A) is more likely to develop as the amount of menthol decreases. The amount of menthol is preferably 0.001 to 0.6% by weight, more preferably 0.001 to 0.4% by weight, from the viewpoint of ease of manifesting the refreshing effect of component (A) and the suppression of irritation caused by menthol and the excessively cool feeling. . In particular, 0.001 to 0.2% by weight is preferable since there is no irritation of menthol and the effect of enhancing the refreshing feeling of component (A) can be confirmed. In the case where menthol is not blended, since there is no refreshing feeling, the effect of component (A) that enhances it is not exhibited.

  Menthol may be chemically synthesized, or may be an essential oil or extract obtained from a plant derived from Menta Piperita species or Menta Albensis species such as peppermint oil and light-loading oil. When using a natural extract such as peppermint oil or thin cargo oil, the amount of menthol is calculated by quantitatively using an analytical instrument such as gas chromatography.

  Menthol may be blended with component (A) and other flavor components and blended in the oral composition of the present invention as a flavor or may be blended alone. In this case, examples of the flavor component (fragrance) used as a flavor include spearmint oil, anethole, eucapritol, eugenol, methyl salicylate, cinnamic aldehyde, cis-3-hexenol, limonene, fruit flavor and the like.

  The oral composition of the present invention preferably contains a surfactant in addition to the components (A) and (B). The surfactant is not particularly limited as long as it is used for an oral composition, but an anionic surfactant and a nonionic surfactant are preferable.

  Anionic surfactants include alkyl sulfate salts such as sodium lauryl sulfate and sodium myristyl sulfate; N-acyl amino acid salts such as sodium lauroyl sarcosine; acyl taurine salts such as sodium lauroyl methyl taurine; sodium coconut oil fatty acid ethyl ester sodium sulfonate And fatty acid ester sulfonates such as salts. Of these, alkyl sulfate salts such as sodium lauryl sulfate and sodium myristyl sulfate and acyl taurine salts such as sodium lauroylmethyl taurate are preferred from the viewpoint of irritation and aftertaste.

  These anionic surfactants can be used alone or in combination of two or more, and the content thereof is 0.001 to 2% by mass in the oral composition of the present invention from the viewpoint of stability and irritation. More preferably, the content is 0.001 to 1.5% by mass, particularly 0.001 to 1% by mass.

  Nonionic surfactants include polyoxyethylene hydrogenated castor oil, sucrose fatty acid ester, sorbitan fatty acid ester, glycerin fatty acid ester, polyglycerin fatty acid ester, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene sorbit fatty acid ester, polyoxyethylene Fatty acid esters such as glycerin fatty acid ester and polyethylene glycol fatty acid ester, polyoxyethylene phytosterol, polyoxyethylene phytostanol, polyoxyethylene lanolin, polyoxyethylene lanolin alcohol, polyoxyethylene alkylamine, polyoxyethylene fatty acid amide, polyoxy Ethylene alkyl phenyl formaldehyde condensate, polyoxyethylene alkyl ether, polyoxyethylene Emissions polyoxypropylene alkyl ethers, polyoxyethylene polyoxypropylene copolymers, polyoxyethylene alkyl phenyl ethers, polyoxyethylene fatty acid ethanol amides. Among these, in terms of aftertaste, polyoxyethylene hydrogenated castor oil, sucrose fatty acid esters and glycerin fatty acid esters having about 8 to 20 carbon atoms in the fatty acid are preferable.

  These nonionic surfactants can be used alone or in combination of two or more thereof, and the content thereof is 0.001 to 4% by mass in the oral composition of the present invention in terms of stability and aftertaste. In particular, 0.001-2 mass% is preferable.

  The oral composition of the present invention can further contain various components generally used in oral compositions. Examples of such components include sodium monofluorophosphate, sodium fluoride, potassium fluoride, stannous fluoride, sodium chloride, aluminum lactate, glycyrrhetinic acid, allantochlorohydroxyaluminum, lysozyme chloride, epsilon aminocaproic acid, azulene, Copper chlorophyllin sodium, copper gluconate, aluminum lactate, dl-tocopherol acetate, potassium nitrate, sodium tripolyphosphate, zeolite, dextranase, amylase, zinc citrate, zinc chloride and other active ingredients: anhydrous silicic acid, calcium hydrogen phosphate, Abrasives such as calcium carbonate; wetting agents such as propylene glycol, polyethylene glycol, sorbitol, xylitol, erythritol, reduced maltose starch syrup (maltitol), glycerin; carboxy Binders such as sodium tilcellulose and carrageenan; preservatives such as methyl paraoxybenzoate; fungicides such as triclosan, isopropylmethylphenol, chlorhexidine salts, cetylpyridinium chloride; anti-inflammatory agents such as tranexamic acid; sodium hydroxide and hydroxide PH adjusting agents such as potassium; coloring agents; foaming agents and the like. In addition, water such as purified water is used as the medium.

  The oral composition of the present invention can be used as, for example, a powder dentifrice, a moisturizing dentifrice, a toothpaste, a liquid dentifrice, a mouthwash, etc. It can be produced according to a general production method.

Examples 1-9 and Comparative Examples 1-6
According to conventional methods, toothpaste shown in Table 1 (Examples 1-1 to 1-9, Comparative Examples 1-1 to 1-6) and mouthwashes shown in Table 2 (Examples 2-1 to 2-6, Comparative examples 2-1 to 2-9) were prepared. As the “fragrance” in the table, the one containing neither component (A) nor component (B) (Reference 1) was used. These toothpastes and mouthwashes were evaluated by three specialist panels for “freshness of flavor” and “sustainability of coolness” after rinsing.

Reference 1 (fragrance composition described in Table 1 and Table 2)
Spearmint oil 600 (parts by weight)
Anetor 180
Eucalyptol 160
Limonene 40
Eugenol 20
Total 1000

<Evaluation method>
Toothbrushing: 1 g of the prepared toothpaste was taken in a toothbrush and brushed for 1 minute to evaluate the refreshing flavor and the refreshing strength 15 minutes after rinsing.
Mouthwash: 10 ml of the prepared mouthwash was contained in the mouth, and after mouthwash for 20 seconds, the freshness of the flavor and the strength of the refreshing feeling 15 minutes after exhaling were evaluated.

・ Evaluation criteria of freshness of flavor 1: Not refreshing 2: Not very refreshing 3: Slightly refreshing 4: Refreshing

・ Evaluation criteria for the refreshing sensation 1: not remaining 2: slightly remaining 3: slightly remaining 4: strongly remaining 5: very strong

  As is clear from Tables 1 and 2, the toothpastes (Examples 1-1 to 1-9) and mouthwashes (Examples 2-1 to 2-9) that are the products of the present invention are both contained in menthol. However, compared with the same comparative example, the refreshing feeling continued and the refreshing flavor was provided.

Claims (2)

An oral composition comprising components (A) and (B), wherein the weight ratio (B) :( A) of component (B) to component (A) is from 1: 0.001 to 1: 0.1.
(A) one or more terpenes selected from α-ferrandolene, aromadendrene, sabinene, 3-carene, tarpinene, elemen, ocimene and nerolidol
(B) Menthol   The composition for oral cavity according to claim 1, wherein the content of the component (B) is 0.001 to 0.6% by weight.