JP2001122751A - Composition for oral cavity - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a composition for the oral cavity which is excellent in halitosis protective effect and also has good flavor and sensation in taking the composition. SOLUTION: The composition for the oral cavity comprises (A) >=0.05 wt.% of tea tree oil, (B) L-menthol in the same or more amount based on the weight of the ingredient (A) and (C) alcohols selected from the group consisting of ethanol, propylene glycol, glycerol and 1,3-butylene glycol in an amount of 30-450 times the weight of the ingredient (A).

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a composition for oral cavity which has an excellent effect of preventing bad breath and has a good feeling of taking.

[0002]

2. Description of the Related Art Tea tree oil is known to be useful as a compounding component for cosmetics, pharmaceuticals, etc. because of its broad antibacterial spectrum. It is also known that the compound has an effect of preventing bad breath and can be added to a composition for oral cavity (Japanese Patent Application Laid-Open No. 6-345616). Also, L-
It is also known that the use of tea tree oil in combination with menthol improves the refreshing feeling of L-menthol (JP-A-9-263786).

[0003]

By the way, it is necessary to add about 0.05% by weight (hereinafter simply referred to as "%") of the composition for oral cavity to incorporate tea tree oil to exhibit an antibacterial effect and obtain a sufficient effect of preventing bad breath. ).
However, a composition containing 0.05% or more of tea tree oil has a noticeable odor of the tea tree oil itself, and has a problem in application to the oral cavity. Therefore, an object of the present invention is to provide a composition for oral cavity which is excellent in the effect of preventing bad breath by tea tree oil and has a good feeling of taking.

[0004]

The inventors of the present invention have conducted various studies in order to achieve both the effect of preventing bad breath and the feeling of ingestion. As a result, a certain amount or more of L-menthol and a certain amount of L-menthol have been added. It has been found that this problem can be solved by using in combination with specific alcohols.

That is, the present invention relates to the following components (A), (B) and (C), (A) tea tree oil 0.05% or more, (B) L-menthol, an equivalent weight of the component (A). As described above, (C) an oral composition containing 30 to 450 times by weight of one or more alcohol components (A) selected from ethanol, propylene glycol, glycerin and 1,3-butylene glycol is provided.

[0006]

BEST MODE FOR CARRYING OUT THE INVENTION The tea tree oil (A) used in the present invention is extracted by steam distillation or a hydrophobic organic solvent from leaves, bark or trees of shrub tea trees (Melaleuca alternifolia) growing in wetlands in Australia. Essential oil. In the case of extracting with an organic solvent, an organic solvent such as ethanol, methanol, propylene glycol, 1,3-butylene glycol, water, or a mixture of water and an organic solvent is used as the extraction solvent. As a purification method after the extraction, a method known per se such as filtration or fractionation treatment can be adopted.

The content of the tea tree oil is 0.00 in terms of essential oil having a terpinen-4-ol content of 35% in the total amount of the oral composition from the viewpoint of the effect of preventing bad breath and the feeling of taking.
5% or more is required, and 0.05 to 1%, particularly 0.05
~ 0.3% is preferred. If it is less than 0.05%, a sufficient bad breath preventing effect cannot be obtained.

[0008] The (B) L-menthol used in the present invention may be isolated or synthesized from an essential oil, or an essential oil containing L-menthol, for example, Japanese peppermint oil, peppermint oil, spearmint oil, mitcham. Seaweed oil or the like may be used as it is.

From the viewpoint of masking the odor of tea tree oil, the compounding amount of L-menthol must be equal to or more than 1 times the weight of tea tree oil (A).
It is preferably from 10 to 10 times by weight, particularly preferably from 1 to 6 times by weight. If the amount is less than the equivalent weight of the component (A), a sufficient masking effect cannot be obtained.

In addition, L-menthol is preferably incorporated in the oral composition of the present invention in an amount of 0.05 to 2%, particularly 0.05 to 1%, from the viewpoint of refreshing feeling and bitterness.

The alcohol (C) used in the present invention is at least one selected from ethanol, propylene glycol, glycerin and 1,3-butylene glycol. These alcohols may be used in combination of two or more. Good.

The amount of the component (C) is from 30 to 4 with respect to the tea tree oil (A) from the viewpoint of the masking effect of the odor of tea tree oil and the effect of improving the feeling of taking.
50 times by weight is required, and 40 to 400 times by weight, especially 4 times
It is preferably from 0 to 200 times by weight.

The form of the oral composition of the present invention includes toothpaste, liquid dentifrice, mouthwash, mouth freshener, liquid impregnated dental floss, and the like.

The oral composition of the present invention contains, in addition to the above-mentioned components,
Depending on the form, water and other appropriate components are used.
For example, in the case of toothpaste, dibasic calcium phosphate
Abrasives such as dihydrate and anhydride, calcium carbonate, calcium pyrophosphate, calcium sulfate, insoluble sodium metaphosphate, non-quality silica, crystalline silica, aluminosilicate, aluminum hydroxide, aluminum oxide, resin, etc. Binders such as carboxymethylcellulose, hydroxyethylcellulose, alginate, carrageenan, gum arabic, and polyvinyl alcohol (0.3 to 5%); sodium lauryl sulfate, sodium dodecylbenzenesulfonate, and hydrogenated coconut fatty acids Sodium monoglyceride monosulfate, sodium lauryl sulfoacetate, sodium N-lauroyl sarcosinate, N-acyl glutamate,
Foaming agents (0-5%) such as lauryl diethanol amide and sucrose fatty acid ester; and sweeteners such as saccharin sodium, stevioside, neohesperidyl dihydrochalcone, glycyrrhizin, perillartin, p-methoxycinamic aldehyde, thaumatin, preservatives, etc. Is mixed with water and produced according to a conventional method. In addition, in a mouthwash and the like, components according to the properties of the product are appropriately compounded. In addition, it is also possible to appropriately mix perfume material components other than L-menthol, such as carvone, anethole, cineol, methyl salicylate, eugenol, cinnamaldehyde, and menthyl lactate.

[0015]

Examples 1 to 8 and Comparative Examples 1 to 6 Mouthwashes were prepared according to the formulations shown in Tables 1 and 2. Five expert panelists were used to gargle using these mouthwashes, and their flavor and bitterness were organoleptically evaluated based on the following evaluation criteria. The results are shown in Tables 1 and 2.

Flavor Evaluation Method The flavor of each sample was subjected to a sensory evaluation by five panelists. The evaluation was scored according to the following criteria, and the average flavor score of each sample was calculated. (Evaluation criteria) -2: Unpleasant flavor -1: Somewhat unpleasant flavor 0: Neither can be said +1: Somewhat good flavor +2: Good flavor

Bitterness evaluation method At the same time as flavor evaluation, bitterness was evaluated according to the following criteria, and an average bitterness score was calculated. (Evaluation criteria) ++: Strong bitterness is felt (Grade 2) +: Bitterness is felt (Grade 1) ±: Slightly bitterness is felt (Grade 0.5)-: Bitter taste is not felt (Grade 0)

[0018]

[Table 1]

[0019]

[Table 2]

As a result, when the mouthwash contains tea tree oil and L-menthol in an amount equal to or less than 1 part by weight of the same, the tea tree oil and L-menthol in an amount equal to or more than 30 parts by weight of the tea tree oil are added. When less than ethanol, propylene glycol or glycerin is blended, the flavor is unpleasant. When it is blended, it has a particularly bitter taste,
As a result, the flavor becomes unpleasant, but tea tree oil is mixed with L-menthol in an amount equal to or more than that by weight and ethanol, propylene glycol or glycerin in an amount of 30 to 450 times by weight, particularly 40 to 400 times by weight. It can be seen that the flavor becomes better and the feeling of ingestion is significantly improved without bitterness.

Example 9 (mouthwash) (%) dl-α-tocopherol acetate 0.10 benzethonium chloride 0.01 ethanol 5.00 sorbitol 10.00 paraben 0.05 sodium saccharin 0.02 polyoxyethylene hydrogenated castor oil 0.40 Fragrance 0.20 Tea tree oil 0.05 L-menthol 0.05 Purified water Balance total 100.00

Example 10 (mouth rinse) (%) Triclosan 0.10 Sodium fluoride 0.20 Ethanol 12.00 Xylitol 20.00 Paraben 0.05 Dipotassium glycyrrhizinate 0.02 Polyoxyethylene hydrogenated castor oil 50 Fragrance 0.10 Tea tree oil 0.10 L-menthol 0.10 Purified water Total balance 100.00

Example 11 (Dentifrice) (%) Calcium carbonate 30.00 Silicic anhydride 8.00 Triclosan 0.10 Sodium monofluorophosphate 0.70 Glycerin 7.00 Sorbitol (70%) 25.00 Carboxymethylcellulose Sodium 1.00 Carrageenan 0.50 Paraben 0.05 Saccharin sodium 0.20 Sodium lauryl sulfate 1.40 Fragrance 0.30 Tea tree oil 0.20 L-menthol 0.20 Purified water Total balance 100.00

Example 12 (Dentifrice) (%) hydrous silicic acid 25.00 silicic anhydride 2.00 benzethonium chloride 0.10 allantoinchlorohydroxyaluminum 0.30 glycerin 10.00 sorbitol (70%) 25.00 carboxy Sodium methylcellulose 1.70 Paraben 0.05 Saccharin sodium 0.30 Sodium lauryl sulfate 1.20 Polyoxyethylene hydrogenated castor oil 0.20 Fragrance 0.30 Tea tree oil 0.25 L-menthol 0.25 Purified water Total balance 100.00

Each of the mouthwashes and dentifrices of Examples 9 to 12 had a good flavor and an excellent effect of preventing bad breath.

[0026]

According to the present invention, excellent breath odor preventing effect is obtained,
In addition, an oral composition having a good flavor and a good feeling of taking can be obtained.

Continued on front page F-term (reference) 4C083 AA111 AA112 AA121 AA122 AB172 AB322 AB472 AC101 AC102 AC121 AC122 AC132 AC302 AC432 AC482 AC682 AC692 AC782 AC861 AC862 AD272 AD352 AD531 AD532 AD662 CC41 DD22 DD23 EE34

Claims (1)

[Claims] 1. The following components (A), (B) and (C), (A) at least 0.05% by weight of tea tree oil, (B) L-menthol, at least 1 times the weight of component (A), (C) An oral composition containing 30 to 450 times by weight of one or more alcohol components (A) selected from ethanol, propylene glycol, glycerin and 1,3-butylene glycol.