JP2008231046A5 - - Google Patents
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- Publication number
- JP2008231046A5 JP2008231046A5 JP2007074531A JP2007074531A JP2008231046A5 JP 2008231046 A5 JP2008231046 A5 JP 2008231046A5 JP 2007074531 A JP2007074531 A JP 2007074531A JP 2007074531 A JP2007074531 A JP 2007074531A JP 2008231046 A5 JP2008231046 A5 JP 2008231046A5
- Authority
- JP
- Japan
- Prior art keywords
- optically active
- carnitine amide
- amide halide
- optical purity
- crystallization
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000003287 optical effect Effects 0.000 claims description 9
- 238000002425 crystallisation Methods 0.000 claims description 5
- 230000008025 crystallization Effects 0.000 claims description 4
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 claims description 3
- 239000013078 crystal Substances 0.000 claims description 3
- -1 carnitine amide halide Chemical class 0.000 claims 7
- 238000000034 method Methods 0.000 claims 3
- 150000004820 halides Chemical class 0.000 claims 2
- PHIQHXFUZVPYII-LURJTMIESA-N (S)-carnitine Chemical compound C[N+](C)(C)C[C@@H](O)CC([O-])=O PHIQHXFUZVPYII-LURJTMIESA-N 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- 238000000746 purification Methods 0.000 claims 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
- 150000001875 compounds Chemical class 0.000 description 4
- 239000000706 filtrate Substances 0.000 description 2
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007074531A JP2008231046A (ja) | 2007-03-22 | 2007-03-22 | 光学活性カルニチンアミドハロゲン化物の精製方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007074531A JP2008231046A (ja) | 2007-03-22 | 2007-03-22 | 光学活性カルニチンアミドハロゲン化物の精製方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008231046A JP2008231046A (ja) | 2008-10-02 |
| JP2008231046A5 true JP2008231046A5 (enExample) | 2010-04-22 |
Family
ID=39904281
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007074531A Pending JP2008231046A (ja) | 2007-03-22 | 2007-03-22 | 光学活性カルニチンアミドハロゲン化物の精製方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2008231046A (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI485126B (zh) * | 2009-11-18 | 2015-05-21 | Lonza Ag | 製造ｌ－肉鹼的方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1156852B (it) * | 1978-07-10 | 1987-02-04 | Sigma Tau Ind Farmaceuti | Procedimento industriale per la preparazione del d'canforato della l carnitinammide e del d canforato della d carnitinammide e sue applicazioni |
| JPS6191160A (ja) * | 1984-10-09 | 1986-05-09 | Nisshin Flour Milling Co Ltd | Ｌ−カルニチンの製造法 |
| JP2588930B2 (ja) * | 1988-05-13 | 1997-03-12 | 鐘淵化学工業株式会社 | カルニチンの製造方法 |
| US4847409A (en) * | 1988-12-14 | 1989-07-11 | The Nutrasweet Company | Recovery of L-amino acid isomers from their racemic mixtures |
| DE4111913A1 (de) * | 1991-04-12 | 1992-10-15 | Degussa | Verfahren zur herstellung von l-carnitin aus d,l-carnitinnitrilsalzen |
| JPH08119921A (ja) * | 1994-10-24 | 1996-05-14 | Ajinomoto Co Inc | ＤＬ−α−アミノ酸−Ｎ−（Ｓ）−α−アルキルベンジルアミドのジアステレオマ−分割法 |
| JPH10101628A (ja) * | 1996-09-27 | 1998-04-21 | Tosoh Corp | アミノ酸及びその誘導体の高光学純度の光学活性体の製造法 |
| WO2006028068A1 (ja) * | 2004-09-08 | 2006-03-16 | Wako Pure Chemical Industries, Ltd. | Ｌ－カルニチンの精製方法 |
-
2007
- 2007-03-22 JP JP2007074531A patent/JP2008231046A/ja active Pending
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