JP2008208114A5 - - Google Patents
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- JP2008208114A5 JP2008208114A5 JP2007327323A JP2007327323A JP2008208114A5 JP 2008208114 A5 JP2008208114 A5 JP 2008208114A5 JP 2007327323 A JP2007327323 A JP 2007327323A JP 2007327323 A JP2007327323 A JP 2007327323A JP 2008208114 A5 JP2008208114 A5 JP 2008208114A5
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Claims (10)
- 式Ｉのコハク酸塩。
- 銅放射線を用いて測定したとき、２θが１５．８、２１．０および２６．６の±０．１°で特徴的なＸ線粉末回折ピークを有する、請求項１に記載の塩。
- 銅放射線を用いて測定したとき、２θが１５．８、１６．７、２１．０、２４．２および２６．６の±０．１°で特徴的なＸ線粉末回折ピークを有する、請求項１に記載の塩。
- 図１の特徴的なＸ線粉末回折パターンを有する、請求項１に記載の塩。
＜図１＞
- 融解開始温度が１８４±３℃である、請求項１に記載の塩。
- 湿度約１％〜９０％（±２％）で行った等温（２５．１±０．１℃）水分吸着試験において、９０±２％の相対湿度で０．５％未満重量が増加する、請求項１に記載の塩。
- 無水である、請求項１に記載の塩。
- 請求項１〜７のいずれか一項に記載のコハク酸塩と、薬学的に許容できる担体とを含む医薬組成物。
- 精神病性障害、妄想性障害、および薬物精神病；不安障害、運動障害、気分障害、神経変性障害、および薬物嗜癖を治療するための、請求項８に記載の組成物。
- 認知症、アルツハイマー病、多発梗塞性認知症、アルコール認知症、または他の薬物関連認知症、頭蓋内腫瘍もしくは脳外傷に関連する認知症、ハンチントン病もしくはパーキンソン病に関連する認知症、またはＡＩＤＳに関連した認知症；せん妄；健忘性障害；外傷後ストレス障害；知能障害；学習障害；注意欠陥／多動性障害；加齢関連認知機能低下、軽度、中等度、または重度の型の大うつ病エピソード；躁病気分エピソードまたは混合性気分エピソード；軽躁病気分エピソード；非定型の特徴を有するうつ病エピソード；メランコリー型の特徴を有するうつ病エピソード；緊張病性の特徴を有するうつ病エピソード；産後の発症を伴う気分エピソード；脳卒中後うつ病；大うつ病性障害；気分変調障害；軽症うつ病性障害；月経前不快気分障害；統合失調症の精神病後うつ病性障害；妄想性障害または統合失調症を含む精神病性障害との混合型の大うつ病性障害；双極Ｉ型障害、双極ＩＩ型障害、気分循環性障害を含む双極性障害；パーキンソン病；ハンチントン病；認知症、アルツハイマー病、多発梗塞性認知症、ＡＩＤＳに関連した認知症、前頭側頭型認知症；脳外傷に関連する神経変性；脳卒中に関連する神経変性；脳梗塞に関連する神経変性；低血糖によって誘発される神経変性；てんかん性痙攣に関連する神経変性；神経毒中毒に関連する神経変性；多系統萎縮症、妄想型、解体型、緊張型、鑑別不能型、または残遺型；統合失調症様障害；妄想型またはうつ病型の分裂感情障害；妄想性障害；物質誘発性精神病性障害、アルコール、アンフェタミン、カンナビス、コカイン、幻覚発現物質、吸入剤、オピオイド、またはフェンシクリジンによって誘発される精神病；妄想型の人格障害；統合失調型の人格障害からなる群から選択される障害を治療するための、請求項８に記載の組成物。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87126006P | 2006-12-21 | 2006-12-21 | |
| US60/871260 | 2006-12-21 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008208114A JP2008208114A (ja) | 2008-09-11 |
| JP2008208114A5 true JP2008208114A5 (ja) | 2011-02-03 |
| JP5254602B2 JP5254602B2 (ja) | 2013-08-07 |
Family
ID=39321475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007327323A Expired - Fee Related JP5254602B2 (ja) | 2006-12-21 | 2007-12-19 | ２−（（４−（１−メチル−４−（ピリジン−４−イル）−１ｈ−ピラゾール−３−イル）フェノキシ）メチル）キノリンのコハク酸塩 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US8283471B2 (ja) |
| EP (1) | EP2125786B1 (ja) |
| JP (1) | JP5254602B2 (ja) |
| KR (2) | KR20120043775A (ja) |
| CN (1) | CN101611029B (ja) |
| AR (1) | AR064417A1 (ja) |
| AT (1) | ATE502028T1 (ja) |
| AU (1) | AU2007343135B2 (ja) |
| BR (1) | BRPI0720936A2 (ja) |
| CA (1) | CA2673435C (ja) |
| CY (1) | CY1111919T1 (ja) |
| DE (1) | DE602007013294D1 (ja) |
| DK (1) | DK2125786T3 (ja) |
| ES (1) | ES2360014T3 (ja) |
| HK (1) | HK1134670A1 (ja) |
| IL (1) | IL199389A (ja) |
| MX (1) | MX2009006528A (ja) |
| NZ (1) | NZ577716A (ja) |
| PL (1) | PL2125786T3 (ja) |
| PT (1) | PT2125786E (ja) |
| RU (1) | RU2430918C2 (ja) |
| SI (1) | SI2125786T1 (ja) |
| TW (1) | TWI359660B (ja) |
| WO (1) | WO2008084299A1 (ja) |
| ZA (1) | ZA200904230B (ja) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010033045A1 (en) * | 2008-09-16 | 2010-03-25 | Igor Anatolievich Pomytkin | Compositions and methods for prevention or treatment of beta amyloid deposition |
| TWI396689B (zh) * | 2008-11-14 | 2013-05-21 | Amgen Inc | 作為磷酸二酯酶１０抑制劑之吡衍生物 |
| US20120214842A1 (en) | 2011-02-18 | 2012-08-23 | Exonhit Therapeutics Sa | Methods for treating diseases of the retina |
| EP2975037A4 (en) | 2013-03-15 | 2016-08-10 | Daiichi Sankyo Co Ltd | BENZOTHIOPHENE DERIVATIVE |
| US10039764B2 (en) | 2013-07-12 | 2018-08-07 | University Of South Alabama | Treatment and diagnosis of cancer and precancerous conditions using PDE10A inhibitors and methods to measure PDE10A expression |
| KR102233916B1 (ko) * | 2019-05-28 | 2021-03-30 | 주식회사 엘지생활건강 | Pq1 숙신산을 포함하는 피부 보습, 주름 개선 및 탄력 증진용 조성물 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5795909A (en) * | 1996-05-22 | 1998-08-18 | Neuromedica, Inc. | DHA-pharmaceutical agent conjugates of taxanes |
| ATE369330T1 (de) * | 2001-02-12 | 2007-08-15 | Wyeth Corp | O-desmethyl-venlafaxine succinat salz |
| ES2258652T3 (es) * | 2001-11-29 | 2006-09-01 | Pfizer Products Inc. | Sales de succinato de 5,8,14-triazatetraciclo(10.3.1.02,11.04,9)-hexadeca-2(11),3,5,7,9-pentaeno y composiciones farmaceuticas de los mismos. |
| UA75482C2 (en) * | 2001-12-12 | 2006-04-17 | Pfizer Prod Inc | Salts of e-2-methoxy-n-(3-{4-[3-methyl-4-(6-methylpyridine-3-yloxy)phenylamino]quinozaline -6-yl}alyl)acetamide, a method for the preparation and use thereof for the treatment of cancer |
| BRPI0413595B8 (pt) * | 2003-08-18 | 2021-05-25 | H Lundbeck As | sal de malonato, composição farmacêutica, uso de um sal de malonato, e, método de fabricação de um composto |
| PL1841757T3 (pl) * | 2005-01-07 | 2010-10-29 | Pfizer Prod Inc | Heteroaromatyczne związki chinoliny i ich zastosowanie jako inhibitorów PDE10 |
| WO2006078825A2 (en) | 2005-01-21 | 2006-07-27 | Cabot Corporation | Processes for forming nanoparticles |
| BRPI0619962A2 (pt) * | 2005-12-16 | 2011-10-25 | Wyeth Corp | composições liofilizadas de um composto triazolopirimidina |
-
2007
- 2007-12-03 ES ES07858987T patent/ES2360014T3/es active Active
- 2007-12-03 AU AU2007343135A patent/AU2007343135B2/en not_active Ceased
- 2007-12-03 NZ NZ577716A patent/NZ577716A/xx not_active IP Right Cessation
- 2007-12-03 KR KR1020127009903A patent/KR20120043775A/ko not_active Application Discontinuation
- 2007-12-03 DK DK07858987.6T patent/DK2125786T3/da active
- 2007-12-03 CA CA2673435A patent/CA2673435C/en not_active Expired - Fee Related
- 2007-12-03 EP EP07858987A patent/EP2125786B1/en not_active Not-in-force
- 2007-12-03 BR BRPI0720936-3A patent/BRPI0720936A2/pt not_active IP Right Cessation
- 2007-12-03 DE DE602007013294T patent/DE602007013294D1/de active Active
- 2007-12-03 AT AT07858987T patent/ATE502028T1/de active
- 2007-12-03 SI SI200730561T patent/SI2125786T1/sl unknown
- 2007-12-03 WO PCT/IB2007/003819 patent/WO2008084299A1/en active Application Filing
- 2007-12-03 CN CN200780051566.5A patent/CN101611029B/zh not_active Expired - Fee Related
- 2007-12-03 US US12/515,612 patent/US8283471B2/en not_active Expired - Fee Related
- 2007-12-03 PL PL07858987T patent/PL2125786T3/pl unknown
- 2007-12-03 PT PT07858987T patent/PT2125786E/pt unknown
- 2007-12-03 KR KR1020097015193A patent/KR20090092338A/ko not_active Application Discontinuation
- 2007-12-03 RU RU2009123347/04A patent/RU2430918C2/ru not_active IP Right Cessation
- 2007-12-03 MX MX2009006528A patent/MX2009006528A/es active IP Right Grant
- 2007-12-18 AR ARP070105692A patent/AR064417A1/es not_active Application Discontinuation
- 2007-12-19 JP JP2007327323A patent/JP5254602B2/ja not_active Expired - Fee Related
- 2007-12-20 TW TW096148920A patent/TWI359660B/zh not_active IP Right Cessation
-
2009
- 2009-06-16 IL IL199389A patent/IL199389A/en active IP Right Review Request
- 2009-06-17 ZA ZA200904230A patent/ZA200904230B/xx unknown
-
2010
- 2010-02-10 HK HK10101480.3A patent/HK1134670A1/xx not_active IP Right Cessation
-
2011
- 2011-05-17 CY CY20111100481T patent/CY1111919T1/el unknown
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